Michael Shoykhet, M.D., Ph.D.  shoykhet_m@kids.wustl.edu

Assistant Professor of Pediatrics, Critical Care Medicine
Critical Care MedicineDevelopmental Biology

phone: (314) 454-2527

Clinical Interests

Cardiac Arrest, Neurocritical Care, Resuscitation


  • B.A., Cornell University 1996
  • Ph.D., University of Pittsburgh2003
  • M.D., University of Pittsburgh2005


  • Internship in Pediatrics, Children’s Hospital of Pittsburgh of UPMC2005 - 2006
  • Residency, Children’s Hospital of Pittsburgh of UPMC2006 - 2007
  • Fellowship in Pediatric Critical Care, Children’s Hospital of Pittsburgh of UPMC2007 - 2010

Licensure and Board Certification

  • PA, Pennsylvania MD2007
  • General Pediatrics2009
  • MO, Missouri2010
  • Pediatric Critical Care2010


  • Howard Hughes Undergraduate Research Fellowship Cornell University1995
  • Cum Laude, Cornell University1996
  • NIH Medical Scientist Training Program Fellowship University of Pittsburgh School of Medicine1996
  • Morris H. and Gertrude M. Harris Foundation Scholarship University of Pittsburgh School of Medicine2004
  • Alpha Omega Alpha University of Pittsburgh School of Medicine2005
  • Cum Laude, University of Pittsburgh School of Medicine2005
  • Richard L. Day Prize in Pediatrics Department of Pediatrics, University of Pittsburgh School of Medicine2005
  • “Praise from Patients” Certificate of Recognition Children’s Hospital of Pittsburgh of UPMC2009
  • McGrevin Foundation Award for Excellence in Patient-Centered Research Department of Critical Care, University of Pittsburgh School of Medicine2009
  • Young Investigator’s Travel Award Pediatric Academic Societies/Society for Pediatric Research2009
  • Child Health Research Center in Developmental Biology Fellow2011
  • Children’s Discovery Institute Faculty Fellow, St Louis Children’s Hospital, Washington University School of Medicine2011
  • Pediatric Critical Care Scientist Development Program Fellow2011
  • Child Health Research Center in Developmental Biology Fellow2011 - 2013
  • NIH Loan Repayment Fellow2014 - 2016

Recent Publications view all (15)

Publication Co-Authors

  1. Shoykhet M, Middleton JW. Cardiac Arrest-Induced Global Brain Hypoxia-Ischemia during Development Affects Spontaneous Activity Organization in Rat Sensory and Motor Thalamocortical Circuits during Adulthood. Front Neural Circuits. 2016;10:68. PMCID:PMC4996986  PMID:27610077  
  2. Stevens RD, Shoykhet M, Cadena R. Emergency Neurological Life Support: Intracranial Hypertension and Herniation. Neurocrit Care. 2015;23 Suppl 2:S76-82. PMCID:PMC4791176  PMID:26438459  
  3. Aravamuthan BR, Shoykhet M. Long-term increase in coherence between the basal ganglia and motor cortex after asphyxial cardiac arrest and resuscitation in developing rats. Pediatr Res. 2015;78(4):371-9. PMCID:PMC4791178  PMID:26083760  
  4. Fu M, Landreville S, Agapova OA, Wiley LA, Shoykhet M, Harbour JW, Heuckeroth RO. Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction. J Clin Invest. 2013;123(12):5152-64. doi:10.1172/JCI67653  PMCID:PMC3859411  PMID:24177421  
  5. Guilliams K, Rosen M, Buttram S, Zempel J, Pineda J, Miller B, Shoykhet M. Hypothermia for pediatric refractory status epilepticus. Epilepsia. 2013;54(9):1586-94. doi:10.1111/epi.12331  PMCID:PMC3975144  PMID:23906244  
  6. Pihlajoki M, Gretzinger E, Cochran R, Kyrönlahti A, Schrade A, Hiller T, Sullivan L, Shoykhet M, Schoeller EL, Brooks MD, Heikinheimo M, Wilson DB. Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice. Endocrinology. 2013;154(5):1754-67. doi:10.1210/en.2012-1892  PMCID:PMC3628026  PMID:23471215  
  7. Kirk KA, Shoykhet M, Jeong JH, Tyler-Kabara EC, Henderson MJ, Bell MJ, Fink EL. Dysautonomia after pediatric brain injury. Dev Med Child Neurol. 2012;54(8):759-64. doi:10.1111/j.1469-8749.2012.04322.x  PMCID:PMC3393822  PMID:22712762  
  8. Shoykhet M, Simons DJ, Alexander H, Hosler C, Kochanek PM, Clark RS. Thalamocortical dysfunction and thalamic injury after asphyxial cardiac arrest in developing rats. J Neurosci. 2012;32(14):4972-81. doi:10.1523/JNEUROSCI.5597-11.2012  PMCID:PMC3350787  PMID:22492052  
  9. Su E, Shoykhet M, Bell MJ. Severe hypernatremia in a hospitalized child: munchausen by proxy. Pediatr Neurol. 2010;43(4):270-3. doi:10.1016/j.pediatrneurol.2010.05.002  PMCID:PMC3095029  PMID:20837306  
  10. Baltagi SA, Shoykhet M, Felmet K, Kochanek PM, Bell MJ. Neurological sequelae of 2009 influenza A (H1N1) in children: a case series observed during a pandemic. Pediatr Crit Care Med. 2010;11(2):179-84. doi:10.1097/PCC.0b013e3181cf4652  PMID:20081552  
  11. Shoykhet M, Simons DJ. Development of thalamocortical response transformations in the rat whisker-barrel system. J Neurophysiol. 2008;99(1):356-66. doi:10.1152/jn.01063.2007  PMID:17989240  
  12. Shoykhet M, Land PW, Simons DJ. Whisker trimming begun at birth or on postnatal day 12 affects excitatory and inhibitory receptive fields of layer IV barrel neurons. J Neurophysiol. 2005;94(6):3987-95. doi:10.1152/jn.00569.2005  PMID:16093330  
  13. Shoykhet M, Shetty P, Minnery BS, Simons DJ. Protracted development of responses to whisker deflection in rat trigeminal ganglion neurons. J Neurophysiol. 2003;90(3):1432-7. doi:10.1152/jn.00419.2003  PMID:12801899  
  14. Shetty P, Shoykhet M, Simons DJ. Whisker plucking alters responses of rat trigeminal ganglion neurons. Somatosens Mot Res. 2003;20(3-4):233-8. doi:10.1080/08990220310001622951  PMID:14675962  
  15. Shoykhet M, Doherty D, Simons DJ. Coding of deflection velocity and amplitude by whisker primary afferent neurons: implications for higher level processing. Somatosens Mot Res. 2000;17(2):171-80. PMID:10895887  
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