Department of Pediatrics

Education

• BS, University of Southern California, 2001
• MS, American University of the Caribbean School of Medicine, 2002
• MD, American University of the Caribbean School of Medicine, 2005

Training

• Pediatric Residency, University of Illinois College of Medicine, 2005 - 2008
• Chief Residency, University of Illinois College of Medicine, 2007 - 2008
• Neonatal-Perinatal Fellowship, University of Pittsburgh School of Medicine, 2008 - 2011

Licensure and Board Certification

• IL, Illinois Medical License , 2007
• United States Department of Justice Drug Enforcement Administration Controlled Substance Registration Certificate , 2007
• Illinois State Medical Board Division of Professional Regulation Licensed Physician and Surgeon Controlled Substance License , 2007
• Neonatal Resuscitation Program – Regional Trainer , 2008
• PA, Pennsylvania Medical License , 2008
• Pediatrics , 2008
• Neonatal-Perinatal Medicine , 2012
• Bureau of Narcotics and Dangerous Drugs Missouri Department of Heath and Senior Services Missouri Controlled Substances License , 2016
• MO, Missouri Medical License , 2016

Honors

• Alpha Epsilon Delta Premedical Honor Society, University of Southern California, 1999 - 2001
• Vice President, Phi Sigma Biology Honor Society, University of Southern California, 2000 - 2001
• Student Government Class Representative, American University of the Caribbean School of Medicine, 2001 - 2002
• Student Government Secretary, American University of the Caribbean School of Medicine, 2002 - 2002
• Outstanding Intern of the Year Award, Department of Pediatrics, Children’s Hospital of Illinois, 2006
• Chief Resident, University of Illinois College of Medicine at Peoria, Children’s Hospital of Illinois, 2007 - 2008
• Fellowship Program Delegate, American Academy of Pediatrics, University of Pittsburgh School of Medicine, 2010 - 2011
• Frederick M. Kenny Award in Pediatric Research, Midwest Society of Pediatric Research Annual Meeting, 2010
• David G. Nathan Award in Basic Science Research, Pediatric Academic Societies Annual Meeting, 2011
• Department of Pediatrics Endowed Instructorship Award, Children’s Hospital of Pittsburgh, 2011
• NIH Institutional K12 Research Faculty Training Award, 2011 - 2013
• NIH Pediatric Research Loan Repayment Award, 2013 - 2018
• The Jon F. Watchko, MD Fellowship Mentoring Award, 2014
• Career Mentoring Program (CaMP) Scholar, University of Pittsburgh School of Medicine, 2014 - 2015
• Deans Summer Research Program (SRP) Merit Award to Zerina Hodzic, Medical Student, 2014
• Travel Award for Eastern Society of Pediatric Research to Zerina Hodzic, Medical Student, 2016
• Society for Pediatric Research (SPR) Student Research Award to Olivia Parks, University of Pittsburgh Undergraduate Student, 2016
• Philip Troen, MD, Excellence in Medical Student Research Mentoring Award, University of Pittsburgh School of Medicine, 2016
• Young Investigator Travel Award. Mucosal Immunology Course and Symposium, 2016
• American Association of Immunology Travel Grant for the International Congress of Immunology, 2016
• Travel Award to International Cytokine and Interferon Society to Zerina Hodzic, Medical Student, 2016
• Young Investigator Travel Award. Mucosal Immunology Course and Symposium, MICS 2016, 2016
• Washington University Department of Pediatrics Educational Loan Repayment Award, 2017

Recent Publications view all (38)

Publication Co-Authors

Clifford J. Luke, Ph.D.

Stephen C. Pak, Ph.D.

Gary A. Silverman, M.D., Ph.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Misty Good, M.D., M.S.

1. Hodzic Z, Schill EM, Bolock AM, Good M. IL-33 and the intestine: The good, the bad, and the inflammatory. Cytokine. 2017. PMID:28687373 
2. Rusconi B, Good M, Warner BB. The Microbiome and Biomarkers for Necrotizing Enterocolitis: Are We Any Closer to Prediction? J Pediatr. 2017. PMID:28669607 
3. Cunningham KE, Okolo FC, Baker R, Mollen KP, Good M. Red blood cell transfusion in premature infants leads to worse necrotizing enterocolitis outcomes. J Surg Res. 2017;213:158-165. PMID:28601308 
4. Hodzic Z, Bolock AM, Good M. The Role of Mucosal Immunity in the Pathogenesis of Necrotizing Enterocolitis. Front Pediatr. 2017;5:40. PMCID:PMC5334327  PMID:28316967 
5. Bohnhoff JC, DiSilvio SA, Aneja RK, Shenk JR. Domnina YA, Brozanski BS, Good M. Treatment and follow-up of venous thrombosis in the neonatal intensive care unit: A retrospective study. J Perinatol. 2017;37(3):306-310. doi:10.1038/jp.2016.218   PMID:27906197 
6. Drummond CG, Bolock AM, Ma C, Luke CJ, Good M*, Coyne CB*. Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner. Proc Natl Acad Sci U S A. 2017;114(7):1672-1677. PMCID:PMC5320971  PMID:28137842 
7. Niño DF, Sodhi CP, Egan CE, Zhou Q, Lin J, Lu P, Yamaguchi Y, Jia H, Martin LY, Good M, Fulton WB, Prindle T Jr, Ozolek JA, Hackam DJ. Retinoic Acid Improves Incidence and Severity of Necrotizing Enterocolitis by Lymphocyte Balance Restitution and Repopulation of LGR5+ Intestinal Stem Cells. Shock. 2017;47(1):22-32. PMCID:PMC5167667  PMID:27488085 
8. Good M, Sodhi CP, Yamaguchi Y, Jia H, Lu P, Fulton WB, Martin LY, Prindle T, Nino DF, Zhou Q, Ma C, Ozolek JA, Buck RH, Goehring KC, Hackam DJ. The human milk oligosaccharide 2'-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine. Br J Nutr. 2016;116(7):1175-1187. PMCID:PMC5124125  PMID:27609061 
9. Jia H, Sodhi CP, Yamaguchi Y, Lu P, Martin LY, Good M, Zhou Q, Sung J, Fulton WB, Nino DF, Prindle T Jr, Ozolek JA, Hackam DJ. Pulmonary Epithelial TLR4 Activation Leads to Lung Injury in Neonatal Necrotizing Enterocolitis. J Immunol. 2016;197(3):859-71. PMCID:PMC4955761  PMID:27307558 
10. Kumar P, Monin L, Castillo P, Elsegeiny W, Horne W, Eddens T, Vikram A, Good M, Schoenborn AA, Bibby K, Montelaro RC, Metzger DW, Gulati AS, Kolls JK. Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation. Immunity. 2016;44(3):659-71. PMCID:PMC4794750  PMID:26982366 
11. Egan CE, Sodhi CP, Good M, Lin J, Jia H, Yamaguchi Y, Lu P, Ma C, Branca MF, Weyandt S, Fulton WB, Niño DF, Prindle T Jr, Ozolek JA, Hackam DJ. Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis. J Clin Invest. 2016;126(2):495-508. PMCID:PMC4731173  PMID:26690704 
12. Orabi AI, Sah S, Javed TA, Lemon KL, Good ML, Guo P, Xiao X, Prasadan K, Gittes GK, Jin S, Husain SZ. Dynamic imaging of pancreatic nuclear factor κB (NF-κB) activation in live mice using adeno-associated virus (AAV) infusion and bioluminescence. J Biol Chem. 2016;291(3):1202. PMCID:PMC4714208  PMID:26773130 
13. Zheng M, Horne W, McAleer JP, Pociask D, Eddens T, Good M, Gao B, Kolls JK. Therapeutic Role of Interleukin 22 in Experimental Intra-abdominal Klebsiella pneumoniae Infection in Mice. Infect Immun. 2016;84(3):782-9. PMCID:PMC4771339  PMID:26729763 
14. Niehaus JZ, Miedel MT, Good M, Wyatt AN, Pak SC, Silverman GA, Luke CJ. SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin. Biochemistry. 2015;54(45):6756-9. PMCID:PMC4900762  PMID:26497600 
15. Niehaus JZ, Good M, Jackson LE, Ozolek JA, Silverman GA, Luke CJ. Human SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia. J Histochem Cytochem. 2015;63(11):854-65. PMCID:PMC4812677  PMID:26220980 
16. Barragan M, Good M, Kolls JK. Regulation of Dendritic Cell Function by Vitamin D. Nutrients. 2015;7(9):8127-51. PMCID:PMC4586578  PMID:26402698 
17. Good M, Sodhi CP, Egan CE, Afrazi A, Jia H, Yamaguchi Y, Lu P, Branca MF, Ma C, Prindle T Jr, Mielo S, Pompa A, Hodzic Z, Ozolek JA, Hackam DJ. Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor. Mucosal Immunol. 2015;8(5):1166-79. PMCID:PMC4540669  PMID:25899687 
18. Harmon CM, Azzuqa AA, Ranganathan S, Mahmood B, Good M. Mid-Aortic Syndrome in a Preterm Infant: A Rare Cause of Hypertension. J Pediatr. 2015;167(2):492-e1. PMCID:PMC4516603  PMID:26037732 
19. Wipf P, Eyer BR, Yamaguchi Y, Zhang F, Neal MD, Sodhi CP, Good M, Branca M, Prindle T Jr, Lu P, Brodsky JL, Hackam DJ. Synthesis of anti-inflammatory α-and β-linked acetamidopyranosides as inhibitors of toll-like receptor 4 (TLR4). Tetrahedron Lett. 2015;56(23):3097-3100. PMCID:PMC4518473  PMID:26236050 
20. Sodhi CP, Jia H, Yamaguchi Y, Lu P, Good M, Egan C, Ozolek J, Zhu X, Billiar TR, Hackam DJ. Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the Gut. J Immunol. 2015;194(10):4931-9. PMCID:PMC4417407  PMID:25862813 
21. Orabi AI, Sah S, Javed TA, Lemon KL, Good ML, Guo P, Xiao X, Prasadan K, Gittes GK, Jin S, Husain SZ. Dynamic imaging of pancreatic nuclear factor κB (NF-κB) activation in live mice using adeno-associated virus (AAV) infusion and bioluminescence. J Biol Chem. 2015;290(18):11309-20. PMCID:PMC4416837  PMID:25802340 
22. Raveh-Sadka T, Thomas BC, Singh A, Firek B, Brooks B, Castelle CJ, Sharon I, Baker R, Good M, Morowitz MJ, Banfield JF. Gut bacteria are rarely shared by co-hospitalized premature infants, regardless of necrotizing enterocolitis development. Elife. 2015;4. PMCID:PMC4384745  PMID:25735037 
23. Parks OB, Pociask DA, Hodzic Z, Kolls JK, Good M. Interleukin-22 Signaling in the Regulation of Intestinal Health and Disease. Front Cell Dev Biol. 2015;3:85. PMCID:PMC4710696  PMID:26793707 
24. Good M, Sodhi CP, Hackam DJ. Evidence-based feeding strategies before and after the development of necrotizing enterocolitis. Expert Rev Clin Immunol. 2014;10(7):875-84. PMCID:PMC4113601  PMID:24898361 
25. Lu P, Sodhi CP, Jia H, Shaffiey S, Good M, Branca MF, Hackam DJ. Animal models of gastrointestinal and liver diseases. Animal models of necrotizing enterocolitis: pathophysiology, translational relevance, and challenges. Am J Physiol Gastrointest Liver Physiol. 2014;306(11):G917-28. PMCID:PMC4042110  PMID:24763555 
26. Good M, Sodhi CP, Ozolek JA, Buck RH, Goehring KC, Thomas DL, Vikram A, Bibby K, Morowitz MJ, Firek B, Lu P, Hackam DJ. Lactobacillus rhamnosus HN001 decreases the severity of necrotizing enterocolitis in neonatal mice and preterm piglets: evidence in mice for a role of TLR9. Am J Physiol Gastrointest Liver Physiol. 2014;306(11):G1021-32. PMCID:PMC4042115  PMID:24742987 
27. Afrazi A, Branca MF, Sodhi CP, Good M, Yamaguchi Y, Egan CE, Lu P, Jia H, Shaffiey S, Lin J, Ma C, Vincent G, Prindle T Jr, Weyandt S, Neal MD, Ozolek JA, Wiersch J, Tschurtschenthaler M, Shiota C, Gittes GK, Billiar TR, Mollen K, Kaser A, Blumberg R, Hackam DJ. Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis. J Biol Chem. 2014;289(14):9584-99. PMCID:PMC3975009  PMID:24519940 
28. Brower-Sinning R, Zhong D, Good M, Firek B, Baker R, Sodhi CP, Hackam DJ, Morowitz MJ. Mucosa-associated bacterial diversity in necrotizing enterocolitis. PLoS One. 2014;9(9):e105046. PMCID:PMC4159227  PMID:25203729 
29. Neal MD, Jia H, Eyer B, Good M, Guerriero CJ, Sodhi CP, Afrazi A, Prindle T Jr, Ma C, Branca M, Ozolek J, Brodsky JL, Wipf P, Hackam DJ. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013;8(6):e65779. PMCID:PMC3680486  PMID:23776545 
30. Yazji I, Sodhi CP, Lee EK, Good M, Egan CE, Afrazi A, Neal MD, Jia H, Lin J, Ma C, Branca MF, Prindle T, Richardson WM, Ozolek J, Billiar TR, Binion DG, Gladwin MT, Hackam DJ. Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling. Proc Natl Acad Sci U S A. 2013;110(23):9451-6. PMCID:PMC3677476  PMID:23650378 
31. Hackam DJ, Good M, Sodhi CP. Mechanisms of gut barrier failure in the pathogenesis of necrotizing enterocolitis: Toll-like receptors throw the switch. Semin Pediatr Surg. 2013;22(2):76-82. PMCID:PMC3644853  PMID:23611610 
32. Neal MD, Sodhi CP, Dyer M, Craig BT, Good M, Jia H, Yazji I, Afrazi A, Richardson WM, Beer-Stolz D, Ma C, Prindle T, Grant Z, Branca MF, Ozolek J, Hackam DJ. A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis. J Immunol. 2013;190(7):3541-51. PMCID:PMC3608826  PMID:23455503 
33. Hackam DJ, Afrazi A, Good M, Sodhi CP. Innate immune signaling in the pathogenesis of necrotizing enterocolitis. Clin Dev Immunol. 2013;2013:475415. PMCID:PMC3677005  PMID:23762089 
34. Neal MD, Sodhi CP, Jia H, Dyer M, Egan CE, Yazji I, Good M, Afrazi A, Marino R, Slagle D, Ma C, Branca MF, Prindle T Jr, Grant Z, Ozolek J, Hackam DJ. Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis. J Biol Chem. 2012;287(44):37296-308. PMCID:PMC3481327  PMID:22955282 
35. Sodhi CP, Neal MD, Siggers R, Sho S, Ma C, Branca MF, Prindle T Jr, Russo AM, Afrazi A, Good M, Brower-Sinning R, Firek B, Morowitz MJ, Ozolek JA, Gittes GK, Billiar TR, Hackam DJ. Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice. Gastroenterology. 2012;143(3):708-18.e1-5. PMCID:PMC3584415  PMID:22796522 
36. Good M, Siggers RH, Sodhi CP, Afrazi A, Alkhudari F, Egan CE, Neal MD, Yazji I, Jia H, Lin J, Branca MF, Ma C, Prindle T, Grant Z, Shah S, Slagle D 2nd, Paredes J, Ozolek J, Gittes GK, Hackam DJ. Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium. Proc Natl Acad Sci U S A. 2012;109(28):11330-5. PMCID:PMC3396489  PMID:22733781 
37. Afrazi A, Sodhi CP, Good M, Jia H, Siggers R, Yazji I, Ma C, Neal MD, Prindle T, Grant ZS, Branca MF, Ozolek J, Chang EB, Hackam DJ. Intracellular heat shock protein-70 negatively regulates TLR4 signaling in the newborn intestinal epithelium. J Immunol. 2012;188(9):4543-57. PMCID:PMC3331906  PMID:22461698 
38. Afrazi A, Sodhi CP, Richardson W, Neal M, Good M, Siggers R, Hackam DJ. New insights into the pathogenesis and treatment of necrotizing enterocolitis: Toll-like receptors and beyond. Pediatr Res. 2011;69(3):183-8. PMCID:PMC3125129  PMID:21135755