R. Mark Grady, M.D.  grady@kids.wustl.edu

Associate Professor of Pediatrics, Cardiology
Cardiology

phone: (314) 454-6095

Education

  • BA, Princeton University1984
  • MD, Washington University School of Medicine1989
  • MA, Washington University School of Medicine1989

Training

  • Residency, St. Louis Children's Hospital, Washington University School of Medicine1989 - 1992
  • Fellow, Washington University School of Medicine, St. Louis Children's Hospital1992 - 1997

Licensure and Board Certification

  • MO, 1997
  • American Board of Pediatrics, certificate number 1377 1998
  • American Board of Pediatrics, Subboard of Pediatric Cardiology, certificate number 001377 2005
  • IL, 2011
  • MO, DEA 2011
  • MO, BNDD 2012

Honors

  • Alpha Omege Alpha
  • Merck manual award for oustanding medical student
  • Phi Beta kappa
  • Recipient of the 1999 Richard D. Rowe award for research in pediatric cardiology given by the Society for Pediatric Research
  • Senior book prize for excellence in scholarship
  • Sigma Xi
  • Summa cum laude graduate

Recent Publications view all (31)


Publication Co-Authors

  1. Glucocorticoids for treating paediatric pulmonary hypertension: a novel use for a common medication Cardiol Young. 2017;16:1-3. 
  2. Pulmonary artery acceleration time provides a reliable estimate of invasive pulmonary hemodynamics in children J Am Soc Echocardiogr. 2017;29(11):1056-1065. PMID:27641101 
  3. Potts Shunt and Pediatric Pulmonary Hypertension: What We Have Learned. Ann Thorac Surg. 2016;101(4):1539-43. PMID:26518375 
  4. Recommendations for utilization of the paracorporeal lung assist device in neonates and young children with pulmonary hypertension. Pediatr Transplant. 2016;20(2):256-70. PMID:26899454 
  5. Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction. J Cell Sci. 2016;129(5):898-911. PMCID:PMC4813319  PMID:26769899 
  6. Two deletions overlapping a distant FOXF1 enhancer unravel the role of lncRNA LINC01081 in etiology of alveolar capillary dysplasia with misalignment of pulmonary veins. Am J Med Genet A. 2014. doi:10.1002/ajmg.a.36606  PMID:24842713 
  7. Paracorporeal lung assist devices as a bridge to recovery or lung transplantation in neonates and young children. J Thorac Cardiovasc Surg. 2014;147(1):420-6. doi:10.1016/j.jtcvs.2013.08.078  PMID:24199759 
  8. Molecular and phenotypic characterization of atypical Williams-Beuren syndrome. Clin Genet. 2013. doi:10.1111/cge.12305  PMID:24246242 
  9. Neonatal paracorporeal lung assist device for respiratory failure. Ann Thorac Surg. 2013;95(2):692-4. doi:10.1016/j.athoracsur.2012.05.128  PMID:23336880 
  10. Noncardiac chest pain in children and adolescents: a biopsychosocial conceptualization. Child Psychiatry Hum Dev. 2012;43(1):1-26. doi:10.1007/s10578-011-0240-7  PMID:21701910 
  11. Lung transplantation in children with idiopathic pulmonary arterial hypertension: an 18-year experience. J Heart Lung Transplant. 2011;30(10):1148-52. doi:10.1016/j.healun.2011.04.009  PMID:21620736 
  12. First experience with a paracorporeal artificial lung in a small child with pulmonary hypertension. J Thorac Cardiovasc Surg. 2011;141(6):e48-50. doi:10.1016/j.jtcvs.2011.02.005  PMID:21420104 
  13. Dismal lung transplant outcomes in children with tetralogy of Fallot with pulmonary atresia compared to Eisenmenger syndrome or pulmonary vein stenosis. J Heart Lung Transplant. 2009;28(11):1221-5. doi:10.1016/j.healun.2009.07.010  PMID:19783168 
  14. Beyond Berlin: heart transplantation in the "untransplantable". J Thorac Cardiovasc Surg. 2008;136(2):529-31. doi:10.1016/j.jtcvs.2008.01.032  PMID:18692672 
  15. Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin. J Neurosci. 2006;26(11):2841-51. doi:10.1523/JNEUROSCI.4823-05.2006  PMID:16540561 
  16. Syne proteins anchor muscle nuclei at the neuromuscular junction. Proc Natl Acad Sci U S A. 2005;102(12):4359-64. doi:10.1073/pnas.0500711102  PMCID:PMC555524  PMID:15749817 
  17. Tyrosine-phosphorylated and nonphosphorylated isoforms of alpha-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions. J Cell Biol. 2003;160(5):741-52. doi:10.1083/jcb.200209045  PMCID:PMC2173352  PMID:12604589 
  18. Neurotransmitter receptor dynamics studied in vivo by reversible photo-unbinding of fluorescent ligands. Neuron. 2002;34(6):865-76. PMID:12086635 
  19. Dystroglycan is selectively associated with inhibitory GABAergic synapses but is dispensable for their differentiation. J Neurosci. 2002;22(11):4274-85. doi:20026440  PMID:12040032 
  20. Increased vulnerability to kainate-induced seizures in utrophin-knockout mice. Eur J Neurosci. 2002;15(9):1474-84. PMID:12028357 
  21. Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction. J Biol Chem. 2000;275(41):31986-95. doi:10.1074/jbc.M004775200  PMID:10878022 
  22. Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex. Neuron. 2000;25(2):279-93. PMID:10719885 
  23. Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies. Nat Cell Biol. 1999;1(4):215-20. doi:10.1038/12034  PMID:10559919 
  24. Membrane targeting and stabilization of sarcospan is mediated by the sarcoglycan subcomplex. J Cell Biol. 1999;145(1):153-65. PMCID:PMC2148225  PMID:10189375 
  25. Agrin receptors at the skeletal neuromuscular junction Ann N Y Acad Sci. 1998;841:1-13. PMID:9668217 
  26. Development of the neuromuscular junction: genetic analysis in mice. J Physiol Paris. 1998;92(3-4):167-72. PMID:9789802 
  27. Differential membrane localization and intermolecular associations of ?-dystrobrevin isoforms in skeletal muscle Journal of Cell Biology. 1998;142:1269-1278. 
  28. Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy. Cell. 1997;90(4):729-38. PMID:9288752 
  29. Subtle neuromuscular defects in utrophin-deficient mice. J Cell Biol. 1997;136(4):871-82. PMCID:PMC2132496  PMID:9049252 
  30. Rational approach to use of heparin during cardiac catheterization in children. J Am Coll Cardiol. 1995;25(3):725-9. doi:10.1016/0735-1097(94)00438-V  PMID:7860920 
  31. Transcatheter coil embolisation of a pulmonary arteriovenous malformation in a neonate. Br Heart J. 1994;71(4):370-1. PMCID:PMC483690  PMID:8198890 
Last updated: 08/07/2017
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