Bess A. Marshall, M.D.

Profile picture
Endocrinology and Diabetes

phone: (314) 454-6051

Licensure and Board Certification

  • MO, State Medical License 1990
  • American Board of Pediatrics 1991
  • American Board of Pediatrics, Endocrinology 1995


  • National Merit Scholar
  • Phi Beta Kappa
  • Scholar of the Child Health Research Center of Excellence in Developmental Biology

Recent Publications view all (48)

Publication Co-Authors

  1. Lower Urinary Tract Dysfunction and Associated Pons Volume in Patients with Wolfram Syndrome. J Urol. 2018. PMID:29883657 
  2. Monogenic diabetes syndromes: Locus-specific databases for Alström, Wolfram, and Thiamine-responsive megaloblastic anemia. Hum Mutat. 2017;38(7):764-777. PMCID:PMC5535005  PMID:28432734 
  3. Sulfonylurea challenge test in subjects diagnosed with type 1 diabetes mellitus. Pediatr Diabetes. 2017. PMCID:PMC5522783  PMID:28111849 
  4. Neuroimaging evidence of deficient axon myelination in Wolfram syndrome. Sci Rep. 2016;6:21167. PMCID:PMC4758056  PMID:26888576 
  5. Selective cognitive and psychiatric manifestations in Wolfram Syndrome. Orphanet J Rare Dis. 2015;10(1):66. doi:10.1186/s13023-015-0282-1  PMCID:PMC4450481  PMID:26025012 
  6. Remission of severe neonatal diabetes with very early sulfonylurea treatment. Diabetes Care. 2015;38(3):e38-9. doi:10.2337/dc14-2124  PMID:25715421 
  7. A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome. Proc Natl Acad Sci U S A. 2014;111(49):E5292-301. doi:10.1073/pnas.1421055111  PMCID:PMC4267371  PMID:25422446 
  8. Ophthalmologic correlates of disease severity in children and adolescents with Wolfram syndrome. J AAPOS. 2014;18(5):461-465.e1. doi:10.1016/j.jaapos.2014.07.162  PMID:25439303 
  9. Phenotypic characteristics of early Wolfram syndrome. Orphanet J Rare Dis. 2013;8:64. doi:10.1186/1750-1172-8-64  PMCID:PMC3651298  PMID:23981289 
  10. Early presentation of gait impairment in Wolfram Syndrome. Orphanet J Rare Dis. 2012;7:92. doi:10.1186/1750-1172-7-92  PMCID:PMC3551701  PMID:23217193 
  11. Reliability and validity of the Wolfram Unified Rating Scale (WURS). Orphanet J Rare Dis. 2012;7:89. doi:10.1186/1750-1172-7-89  PMCID:PMC3552944  PMID:23148655 
  12. Balance impairment in individuals with Wolfram syndrome. Gait Posture. 2012;36(3):619-24. doi:10.1016/j.gaitpost.2012.06.008  PMCID:PMC3417287  PMID:22771154 
  13. Early brain vulnerability in Wolfram syndrome. PLoS One. 2012;7(7):e40604. doi:10.1371/journal.pone.0040604  PMCID:PMC3394712  PMID:22792385 
  14. Successful sulfonylurea treatment of an insulin-naïve neonate with diabetes mellitus due to a KCNJ11 mutation. Pediatr Diabetes. 2010;11(4):286-8. doi:10.1111/j.1399-5448.2009.00557.x  PMCID:PMC3245710  PMID:19656320 
  15. Hypoglycemia, defective islet glucagon secretion, but normal islet mass in mice with a disruption of the gastrin gene. Gastroenterology. 2003;125(4):1164-74. PMID:14517799 
  16. Fatal malignant hyperthermia-like syndrome with rhabdomyolysis complicating the presentation of diabetes mellitus in adolescent males. Pediatrics. 2003;111(6 Pt 1):1447-52. PMID:12777570 
  17. Hyperinsulinism induced by targeted suppression of beta cell KATP channels. Proc Natl Acad Sci U S A. 2002;99(26):16992-7. doi:10.1073/pnas.012479199  PMCID:PMC139257  PMID:12486236 
  18. Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles. Am J Physiol Endocrinol Metab. 2002;283(2):E241-50. doi:10.1152/ajpendo.00060.2002  PMID:12110528 
  19. Transgenic overexpression of hexokinase II in skeletal muscle does not increase glucose disposal in wild-type or Glut1-overexpressing mice. J Biol Chem. 2000;275(29):22381-6. doi:10.1074/jbc.M001946200  PMID:10764781 
  20. Defective insulin receptors in Rabson-Mendenhall syndrome cause complete peripheral insulin resistance but minimal hepatic insulin response remains. Pediatr Diabetes. 2000;1(2):66-73. doi:10.1034/j.1399-5448.2000.010203.x  PMID:15016231 
  21. Transgenic mice overexpressing GLUT-1 protein in muscle exhibit increased muscle glycogenesis after exercise. Am J Physiol Endocrinol Metab. 2000;278(4):E588-92. PMID:10751190 
  22. Targeted overactivity of beta cell K(ATP) channels induces profound neonatal diabetes. Cell. 2000;100(6):645-54. PMID:10761930 
  23. The head arterial glucose level is not the reference site for generation of the portal signal in conscious dogs. Am J Physiol. 1999;277(4 Pt 1):E678-84. PMID:10516127 
  24. Relative hypoglycemia and hyperinsulinemia in mice with heterozygous lipoprotein lipase (LPL) deficiency. Islet LPL regulates insulin secretion. J Biol Chem. 1999;274(39):27426-32. PMID:10488074 
  25. Differential response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains. Physiol Genomics. 1999;1(1):33-9. PMID:11015559 
  26. GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance. Am J Physiol. 1999;276(2 Pt 1):E390-400. PMID:9950801 
  27. A high fat diet impairs stimulation of glucose transport in muscle. Functional evaluation of potential mechanisms. J Biol Chem. 1998;273(40):26157-63. PMID:9748297 
  28. Dissociation of GLUT4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing GLUT1 in skeletal muscle. J Biol Chem. 1998;273(29):18173-9. PMID:9660777 
  29. Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling. Diabetes. 1998;47(4):632-9. PMID:9568697 
  30. Insulin unmasks a COOH-terminal Glut4 epitope and increases glucose transport across T-tubules in skeletal muscle. J Cell Biol. 1996;135(2):415-30. PMCID:PMC2121045  PMID:8896598 
  31. Differential effects of GLUT1 or GLUT4 overexpression on hexosamine biosynthesis by muscles of transgenic mice. J Biol Chem. 1996;271(38):23197-202. PMID:8798515 
  32. Counterregulation by epinephrine and glucagon during insulin-induced hypoglycemia in the conscious dog. Diabetes Res Clin Pract. 1996;31(1-3):45-56. PMID:8792101 
  33. Skeletal muscle glucose transport and metabolism are enhanced in transgenic mice overexpressing the Glut4 glucose transporter. J Biol Chem. 1995;270(4):1679-84. PMID:7829503 
  34. Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice. J Clin Invest. 1995;95(1):429-32. doi:10.1172/JCI117673  PMCID:PMC295454  PMID:7814644 
  35. Discrete structural domains determine differential endoplasmic reticulum to Golgi transit times for glucose transporter isoforms. J Biol Chem. 1994;269(51):32110-9. PMID:7798206 
  36. Differential effects of GLUT-1 or GLUT-4 overexpression on insulin responsiveness in transgenic mice. Am J Physiol. 1994;267(5 Pt 1):E738-44. PMID:7977725 
  37. Glucose transport activity in skeletal muscles from transgenic mice overexpressing GLUT1. Increased basal transport is associated with a defective response to diverse stimuli that activate GLUT4. J Biol Chem. 1994;269(28):18366-70. PMID:8034582 
  38. Domains that confer intracellular sequestration of the Glut4 glucose transporter in Xenopus oocytes. J Biol Chem. 1993;268(35):26193-9. PMID:8253739 
  39. Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle. J Biol Chem. 1993;268(25):18442-5. PMID:8360145 
  40. Evidence from transgenic mice that glucose transport is rate-limiting for glycogen deposition and glycolysis in skeletal muscle. J Biol Chem. 1993;268(22):16113-5. PMID:8344895 
  41. Relationship between decrements in glucose level and metabolic response to hypoglycemia in absence of counterregulatory hormones in the conscious dog. Diabetes. 1992;41(10):1308-19. PMID:1397705 
  42. Role of hepatic nerves in response of liver to intraportal glucose delivery in dogs. Am J Physiol. 1992;262(5 Pt 1):E679-86. PMID:1590377 
  43. The effects of epinephrine on ketogenesis in the dog after a prolonged fast. Metabolism. 1991;40(10):1057-62. PMID:1943732 
  44. Factors which regulate net hepatic glucose uptake in vivo. JPEN J Parenter Enteral Nutr. 1991;15(3):71S-73S. PMID:1865561 
  45. Effects of small changes in glucagon on glucose production during a euglycemic, hyperinsulinemic clamp. Metabolism. 1991;40(1):66-71. PMID:1984573 
  46. Interaction between insulin and glucose-delivery route in regulation of net hepatic glucose uptake in conscious dogs. Diabetes. 1990;39(1):87-95. PMID:2210065 
  47. Importance of the route of intravenous glucose delivery to hepatic glucose balance in the conscious dog. J Clin Invest. 1987;79(2):557-65. doi:10.1172/JCI112847  PMCID:PMC424126  PMID:2879854 
  48. Insulin, glucagon, and glucose as regulators of hepatic glucose uptake and production in vivo. Diabetes Metab Rev. 1987;3(1):307-32. PMID:3552525 
Last updated: 08/24/2018
© 2019 by Washington University in St. Louis
One Brookings Drive, St. Louis, MO 63130