Jennifer A Wambach, M.D.  wambach_j@kids.wustl.edu

Assistant Professor of Pediatrics, Newborn Medicine
Researcher, Pathobiology
Newborn MedicinePathobiology

phone: (314) 454-6148

Education

  • BS, Vanderbilt University1997
  • MD, Vanderbilt University School of Medicine2001
  • MS, Washington University School of Medicine2010

Training

  • Resident, Pediatrics, Northwestern University School of Medicine2001 - 2004
  • Chief Resident, Pediatrics, Northwestern University School of Medicine2004 - 2005
  • Fellow, Newborn Medicine, Washington University School of Medicine2005 - 2008

Licensure and Board Certification

  • American Board of Pediatrics, General Pediatrics 2004
  • American Board of Pediatrics, Neonatal-Perinatal Medicine 2010

Honors

  • Phi Beta Kappa, Vanderbilt University1997
  • Amos Christie Scholar in Pediatrics, Vanderbilt University School of Medicine1998
  • Microbes and Defense Academic Honor Society, Vanderbilt University School of Medicine1998
  • Dean's Award, Vanderbilt University School of Medicine2001
  • Resident Teaching Award, Northwestern University School of Medicine2002
  • National Institutes of Health, Loan Repayment Program2007 - 2013
  • Spotlight on Women in Medicine, Washington University School of Medicine, Invited Speaker2009
  • American Thoracic Society & chILD Travel Award2010
  • Pediatric UPDATE “Hyaline Membrane Disease and Other Surfactant Disorders.” Volume 32, Issue 8, Invited Discussant2011
  • NHLBI Workshop on Genomics and Lung Diseases2011
  • Japanese Respiratory Society, International Session Award2015
  • American Thoracic Society Meeting, Lead Facilitator for Thematic Poster Session: Lung Development, Pulmonary Hypertension, and Rare Lung Diseases2015
  • Childhood Interstitial Lung Disease (chILD) Annual Meeting, Invited Speaker, Genetic Disorders of Surfactant Function2015
  • NHLBI Workshop on Pediatric Rare Lung Diseases, Invited Participant2015
  • Childhood Interstitial Lung Disease (chILD) Surfactant Week, Invited Webinar Speaker2015
  • American Thoracic Society, Pediatric Core Curriculum, Invited Speaker2016
  • American Thoracic Society, Moderator for Poster Symposium, Neonatal and Congenital Lung Disorders2016
  • NIH Respiratory Integrative Biology and Translational Research Study Section, Early Career Reviewer2016
  • Illumina Whole Genome Sequencing Customer Advisory Group2017
  • Rare Pediatric Respiratory Disease: Science Shapes Precision Care, Scientific Advisory2017

Recent Publications view all (31)


Publication Co-Authors

  1. Survival among Children with “Lethal” Congenital Contracture Syndrome Caused by Novel Mutations in the Gliomedin Gene (GLDN) Hum Mutat. 2017. PMID:28726266 
  2. Generation of mature lung alveolar epithelial cells from human pluripotent stem cells. Cell Stem Cell. 2017. 
  3. Outcomes of Lung Transplantation for Infants and Children with Genetic Disorders of Surfactant Metabolism. J Pediatr. 2017;184:157-164.e2. PMCID:PMC5443678  PMID:28215425 
  4. Accelerating Scientific Advancement for Pediatric Rare Lung Disease Research: Report from a NIH-NHLBI Workshop, September 3-4, 2015. Ann Am Thorac Soc. 2016;12:385-393. PMID:27925785 
  5. Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome. Am J Respir Cell Mol Biol. 2016;55(5):716-721. PMCID:PMC5105181  PMID:27374344 
  6. ATS Core Curriculum 2016: Part III. Pediatric Pulmonary Medicine. Ann Am Thorac Soc. 2016;13(6):955-66. PMID:27295156 
  7. Population-based frequency of surfactant dysfunction mutations in a native Chinese cohort. World J Pediatr. 2016;12(2):190-5. PMID:26547207 
  8. Genetic Factors Contribute to Risk for Neonatal Respiratory Distress Syndrome among Moderately Preterm, Late Preterm, and Term Infants. J Pediatr. 2016;172:69-74.e2. PMCID:PMC4876036  PMID:26935785 
  9. De novo 9q gain in an infant with tetralogy of Fallot with absent pulmonary valve: Patient report and review of congenital heart disease in 9q duplication syndrome. Am J Med Genet A. 2015;167A(12):2966-74. PMID:26768185 
  10. Congenital Acute Myeloid Leukemia with Unique Translocation t(11;19)(q23;p13.3). Cureus. 2015;7(7):e289. PMCID:PMC4523210  PMID:26244121 
  11. Respiratory failure in a term infant with cis and trans mutations in ABCA3. J Perinatol. 2015;35(3):231-2. doi:10.1038/jp.2014.236  PMCID:PMC4341920   PMID:25712598 
  12. Remission of severe neonatal diabetes with very early sulfonylurea treatment. Diabetes Care. 2015;38(3):e38-9. doi:10.2337/dc14-2124  PMID:25715421 
  13. New clinical practice guidelines on the classification, evaluation and management of childhood interstitial lung disease in infants: what do they mean? Expert Rev Respir Med. 2014;1-3. doi:10.1586/17476348.2014.951334  PMID:25138715 
  14. Genotype-phenotype correlations for infants and children with ABCA3 deficiency. Am J Respir Crit Care Med. 2014;189(12):1538-43. doi:10.1164/rccm.201402-0342OC  PMID:24871971 
  15. Synonymous ABCA3 variants do not increase risk for neonatal respiratory distress syndrome. J Pediatr. 2014;164(6):1316-1321.e3. doi:10.1016/j.jpeds.2014.02.021  PMCID:PMC4035386  PMID:24657120 
  16. Two deletions overlapping a distant FOXF1 enhancer unravel the role of lncRNA LINC01081 in etiology of alveolar capillary dysplasia with misalignment of pulmonary veins. Am J Med Genet A. 2014. doi:10.1002/ajmg.a.36606  PMID:24842713 
  17. Neural Tube Defect in Infant of Epileptic Mother Neoreviews. 2013;14:e412. 
  18. Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat. 2013;34(6):801-11. doi:10.1002/humu.22313  PMCID:PMC3663886  PMID:23505205 
  19. Visual Diagnosis: Term Newborn with Abdominal Wall Defect, Ambiguous Genitalia, and Respiratory Distress Neoreviews. 2013;14:e211. 
  20. Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome. Pediatrics. 2012;130(6):e1575-82. doi:10.1542/peds.2012-0918  PMCID:PMC3507255  PMID:23166334 
  21. An intronic ABCA3 mutation that is responsible for respiratory disease. Pediatr Res. 2012;71(6):633-7. doi:10.1038/pr.2012.21  PMCID:PMC3607324  PMID:22337229 
  22. Blueberry Muffin Rash and Respiratory Distress in a Late Preterm Infant American Academy of Pediatrics-Neoreviews. 2012;13:e506. 
  23. Respiratory Distress, Flaccid Abdominal Musculature, and Cryptorchidism American Academy of Pediatrics-Neoreviews. 2011;12:e55-60. 
  24. Surfactant protein-C promoter variants associated with neonatal respiratory distress syndrome reduce transcription. Pediatr Res. 2010;68(3):216-20. doi:10.1203/PDR.0b013e3181eb5d68  PMCID:PMC2921462  PMID:20539253 
  25. Successful sulfonylurea treatment of an insulin-naïve neonate with diabetes mellitus due to a KCNJ11 mutation. Pediatr Diabetes. 2010;11(4):286-8. doi:10.1111/j.1399-5448.2009.00557.x  PMCID:PMC3245710  PMID:19656320 
  26. Women's lifelong exposure to neighborhood poverty and low birth weight: a population-based study. Matern Child Health J. 2009;13(3):326-33. doi:10.1007/s10995-008-0354-0  PMID:18459039 
  27. Skin ulcerations in a preterm newborn American Academy of Pediatrics - Neoreviews. 2009;10:e575-81. 
  28. Population and disease-based prevalence of the common mutations associated with surfactant deficiency. Pediatr Res. 2008;63(6):645-9. doi:10.1203/PDR.0b013e31816fdbeb  PMCID:PMC2765719  PMID:18317237 
  29. Recombination as a mechanism for sporadic mutation in the surfactant protein-C gene. Pediatr Pulmonol. 2008;43(5):443-50. doi:10.1002/ppul.20782  PMCID:PMC2765708  PMID:18383112 
  30. Gastrointestinal polyps in children: advances in molecular genetics, diagnosis, and management. J Pediatr. 2001;138(5):621-8. doi:10.1067/mpd.2001.113619  PMID:11343034 
  31. SMAD4 germline mutations in juvenile polyposis coli. J Pediatr Gastroenterol Nutr. 1999;28(5):538-9. PMID:10328134 
Last updated: 08/29/2017
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