Cardiology | Antiarrhythmic Drug Guide | Other | Midodrine

Midodrine

IV Dose No IV form
Oral dose Adults: 10 mg TID recommended, 3rd dose not later than 6 pm.
Levels unknown
Kinetics Direct effect of metabolite on alpha receptors. Peak levels of metabolite at 1-2 hours, half-life of 3-4 hours.
Cautions Supine and/or sitting hypertension should be checked for after initiation of therapy. Symptoms may include heart pounding, headache, blurred vision.
Interactions May potentiate vagal bradycardia with digoxin. Avoid other vasoconstrictors (e.g. phenylephrine, phenylpropanolamine, dihydroergotamine) Effects antagonized by prazosin)
Preparations ProAmatine scored tablets, 2.5, 5 mg
FDA approval in children no

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