Kenneth E. Remy, M.D., MHSc.  Remy_K@kids.wustl.edu

Assistant Professor of Pediatrics, Critical Care Medicine
Critical Care MedicinePathobiology

phone: (314) 454-2527

Clinical Interests

Dr. Remy is an Assistant Professor of Pediatrics in the Division of Pediatric Critical Care Medicine. He completed dual residencies in Internal Medicine and Pediatrics at Case Western University/University Hospitals of Cleveland/Rainbow Babies and Children’s Hospital in Cleveland, Ohio, Pediatric Critical Care fellowship at New York Presbyterian Hospital-Columbia University in New York City, and Adult Critical Care Fellowship at the National Institutes of Health in Bethesda, MD. He is quadruple boarded in each of these specialties. Additionally, he is formally trained in Global Health and emergency and disaster preparedness; and has received a certificate of clinical research from the National Institutes of Health. He is also the medical director (ICU captain) for Heart Care International’s Medical Missions. Dr. Remy’s has clinical interests in both adults and children in bioethics, international health, humor therapy, and palliative care. Previous research has been in calcium activated chloride channels in airway smooth muscle and in therapeutics to bacillus anthracis induced shock. His research interests are in sepsis, host inflammatory response, and transfusion related immunosuppression.

Education

  • B.S., Advanced Honors Certificate, The University of Delaware1999
  • B.A., Advanced Honors Certificate, The University of Delaware1999
  • M.D., Jefferson Medical College of Thomas Jefferson University2004
  • MSc, Duke University2015

Training

  • Internal Medicine and Pediatrics Combined Residency, Case Medical Center; University Hospitals of Cleveland; Rainbow Babies and Childrens Hospital2004 - 2008
  • Global Health Track Training Certificate, Case Western University, School of Medicine2004 - 2008
  • Management of Humanitarian Emergencies: Focus on Children and Families, Case Western School of Medicine2008 - 2008
  • Pediatric Critical Care Medicine Fellowship, Columbia University School of Medicine; New York Presbyterian Hospital2008 - 2011
  • Adult Critical Care Medicine Fellowship, The National Institutes of Health2011 - 2013
  • Clinical Research Training Certificate With Commendation, The National Insitutes of Health2012 - 2014
  • Critical Care Medicine Postdoctoral Clinical Research Fellowship , National Institutes of Health2013 - 2015

Licensure and Board Certification

  • NY, New York State Office of the Professions; Medical Board2008
  • American Board of Internal Medicine; Internal Medicine2009
  • American Board of Pediatrics; General Pediatrics2009
  • Adult Advanced Cardiac Life Support2012
  • Pediatric Advanced LIfe Support2012
  • MD, Maryland Board of Physicians2012
  • Adult Trauma Life Support2012
  • American Board of Internal Medicine; Critical Care Medicine2013
  • American Board of Pediatrics; Pediatric Critical Care Medicine2014

Honors

  • University Hospitals of Cleveland "UH IDOL" Semifinalist2006
  • Gary Onady National Internal Medicine-Pediatrics Award Recipient2007
  • Who's Who Among American Doctors2007
  • America's Top Pediatricians2007 - 2015
  • Rainbow Ambulatory Practice Senior Resident Award2008
  • Co-Chief Fellow (Selected Position), Columbia University School of Physicians and Surgeons/New York Presbyterian Hospital, Pediatric Critical Care Medicine2010 - 2011
  • Who's Who Among American Pediatricians2011 - 2015
  • The National Institutes of Health Intramural Loan l Repayment Program Award2011 - 2015
  • Chair; Clinical Fellows Committee (Selected Position), The National Institutes of Health2012 - 2014
  • Who's Who Among American Physicians2012 - 2015
  • Chair; Fellow Committee (Selected Position), The National Institutes of Health2012 - 2014
  • National Food and Drug Regulatory Science Symposium First Place Research Award (Top Award)2013
  • The National Institutes of Health Clinical Center Director's Award Recipient2013
  • The Accreditation Council for Graduate Medical Education 2014 David C. Leach Award Recipient2015
  • American Thoracic Society; Critical Care Section Scientific Abstract Award2015
  • The National Institutes of Health Extramural Loan l Repayment Program Award2016 - Pres

Recent Publications view all (24)


Publication Co-Authors

  1. Kristen D. Coletti, Dayanand N. Bagdure, Linda K. Walker, Kenneth E. Remy, and Jason W. Custer. High Flow Nasal Cannula utilization in Pediatric Critical Care: An Observational Study Respiratory Care. 2017. 
  2. Kienzle M, Attebery J, Custer J, Remy K. HIGH-FLOW NASAL OXYGEN REDUCES INTUBATION IN CRITICALLY ILL CHILDREN WITH RESPIRATORY FAILURE. Critical Care Medicine. 2016;44. PMID:27850659  
  3. Allison M. Remy, Kenneth E. Remy, Joan L. Rosenbaum. Palliative Care–Led Meetings for Families of ICU Patients JAMA. 2016;316(15):1597-98. doi:10.1001/jama.2016.14316  PMID:27755629  
  4. Remy KE, Spinella PC. Red blood cell storage age - what we know from clinical trials. Expert Rev Hematol. 2016. PMID:27686118  
  5. Muszynski JA, Spinella PC, Cholette JM, Acker J, Hall MW, Juffermans NP, Kelly DP, Blumberg N, Nicol K, Liedel J, Doctor A, Remy KE, Tucci M, Lacroix J, Norris PJ for the Pediatric Critical Care Blood Research Network (Blood Net). . Transfusion-related Immunomodulation: Review of the literature and implications for pediatric critical illness. Transfusion. 2016. PMID: 27428147  
  6. Jonah E. Attebery, MD, John C. Lin, MD, and Kenneth E. Remy, MD, MHSc. High-Flow Oxygen as Noninvasive Ventilation May Complicate Timely Intubation in Patients with Acute Respiratory Distress Syndrome Critical Care Medicine. 2016. doi:10.1097/CCM.0000000000001782  PMID: 27428147  
  7. Kenneth E. Remy, Irene Cortes-Puch, Charles Natanson and Harvey G. Klein. Transfused fresh blood does not improve outcome, but safety of the oldest stored units still needs to be established compared to current practice Blood. 2016;127(4). 
  8. Remy KE, Sun J, Wang D, Welsh J, Solomon SB, Klein HG, Natanson C, Cortés-Puch I. Transfusion of recently donated (fresh) red blood cells (RBCs) does not improve survival in comparison with current practice, while safety of the oldest stored units is yet to be established: a meta-analysis. Vox Sang. 2016. doi:10.1111/vox.12380  PMID:26848822  
  9. Dante A. Suffredini, Hanish Sampath-Kumar, Yan Li, Lernik Ohanjanian, Kenneth E. Remy, Xizhong Cui, and Peter Q. Eichacker. Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies. Toxins. 2015;7(712):5417-5434. 
  10. Irene Cortés-Puch, Kenneth E. Remy, Steven B. Solomon, Junfeng Sun, Dong Wang, Mariam Al-Hamad, Seth M. Kelly, Derek Sinchar, Landon Bellavia, Tamir Kanias, Mark A. Popovsky, Daniel B. Kim-Shapiro, Harvey G. Klein and Charles Natanson. In a canine pneumonia model of exchange transfusion, altering the age but not the volume of older red blood cells markedly alters outcome Transfusion. 2015;00(0):0. 
  11. Shein SL, Remy KE. High-Flow Nasal Cannula Oxygen in Respiratory Failure. N Engl J Med. 2015;373(14):1373-1375. doi:10.1056/NEJMc1508390#SA3  PMID:26422732  
  12. Solomon SB, Cortés-Puch I, Sun J, Remy KE, Wang D, Feng J, Khan SS, Sinchar D, Kim-Shapiro DB, Klein HG, Natanson C. Transfused older stored red blood cells improve the clinical course and outcome in a canine lethal hemorrhage and reperfusion model. Transfusion. 2015. doi:10.1111/trf.13213  PMID:26175134  
  13. Remy KE. Sedation protocol for critically ill pediatric patients. JAMA. 2015;313(17):1754. doi:10.1001/jama.2015.3459  PMID:25942730  
  14. Ohanjanian L, Remy KE, Li Y, Cui X, Eichacker PQ. An overview of investigational toxin-directed therapies for the adjunctive management of Bacillus anthracis infection and sepsis. Expert Opin Investig Drugs. 2015;1-15. doi:10.1517/13543784.2015.1041587  PMID:25920540  
  15. Remy KE, Natanson C, Klein HG. The influence of the storage lesion(s) on pediatric red cell transfusion. Curr Opin Pediatr. 2015. doi:10.1097/MOP.0000000000000224  PMID:25888156  
  16. Kadri SS, Remy KE, Strich JR, Gea-Banacloche J, Leitman SF. Role of granulocyte transfusions in invasive fusariosis: systematic review and single-center experience. Transfusion. 2015. doi:10.1111/trf.13099  PMID:25857209  
  17. Remy KE, Chertow DS. A place at the table for children in the ebola virus disease discussion. Pediatr Crit Care Med. 2015;16(2):184-5. doi:10.1097/PCC.0000000000000368  PMID:25647125  
  18. Remy KE, Cui X, Li Y, Sun J, Solomon SB, Fitz Y, Barochia AV, Al-Hamad M, Moayeri M, Leppla SH, Eichacker PQ. Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines. Intensive Care Med Exp. 2015;3(9). doi:10.1186/s40635-015-0043-4  PMID:26097803  
  19. Wang D, Cortés-Puch I, Sun J, Solomon SB, Kanias T, Remy KE, Feng J, Alimchandani M, Quezado M, Helms C, Perlegas A, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C. Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of pneumonia. Transfusion. 2014;54(7):1712-24. doi:10.1111/trf.12607  PMCID:PMC4214924  PMID:24588210  
  20. Cortés-Puch I, Wang D, Sun J, Solomon SB, Remy KE, Fernandez M, Feng J, Kanias T, Bellavia L, Sinchar D, Perlegas A, Solomon MA, Kelley WE, Popovsky MA, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C. Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine pneumonia. Blood. 2014;123(9):1403-11. doi:10.1182/blood-2013-11-539353  PMCID:PMC3938151  PMID:24366359  
  21. Gallos G, Remy KE, Danielsson J, Funayama H, Fu XW, Chang HY, Yim P, Xu D, Emala CW Sr. Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2013;305(9):L625-34. doi:10.1152/ajplung.00068.2013  PMCID:PMC3840275  PMID:23997176  
  22. Remy KE, Qiu P, Li Y, Cui X, Eichacker PQ. B. anthracis associated cardiovascular dysfunction and shock: the potential contribution of both non-toxin and toxin components. BMC Med. 2013;11:217. doi:10.1186/1741-7015-11-217  PMCID:PMC3851549  PMID:24107194  
  23. Li Y, Cui X, Solomon SB, Remy K, Fitz Y, Eichacker PQ. B. anthracis edema toxin increases cAMP levels and inhibits phenylephrine-stimulated contraction in a rat aortic ring model. Am J Physiol Heart Circ Physiol. 2013;305(2):H238-50. doi:10.1152/ajpheart.00185.2013  PMCID:PMC3726957  PMID:23585140  
  24. Remy KE, Elder RW, Tsankova NM, Conroy RM. Cerebellar metastatic papillary thyroid carcinoma in a pediatric patient with complex congenital heart disease. J Pediatr Endocrinol Metab. 2012;25(11-12):1195-9. doi:10.1515/jpem-2012-0162  PMID:23329771  
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