Brooke Sadler  sadler@wustl.edu

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Education

  • MA, Arizona State University2010
  • PhD, Arizona State University2014

Training

  • Postdoctoral Research Associate, Washington University School of Medicine2014 - 2016
  • Postdoctoral Research Associate, Washington University School of Medicine2016 - 2019

Honors and Awards

  • NIAMS R01 Diversity Supplement Awardee2017 - 2020
  • Institute for Clinical and Translational Sciences (ICTS) Just in Time Grant Awardee2019

Recent Publications view all (21)


Publication Co-Authors

  1. Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders. Nat Neurosci. 2021. PMID:34239129 
  2. Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report. Crit Care Explor. 2021;3(7):e0500. PMCID:PMC8322565  PMID:34345826 
  3. Extradural decompression versus duraplasty in Chiari malformation type I with syrinx: outcomes on scoliosis from the Park-Reeves Syringomyelia Research Consortium. J Neurosurg Pediatr. 2021;1-9. PMID:34144521 
  4. Rare and de novo coding variants in chromodomain genes in Chiari I malformation. Am J Hum Genet. 2021;108(3):530-531. PMCID:PMC8008482  PMID:33667397 
  5. VWF antigen levels are associated with burden of rare nonsynonymous variants in the VWF gene. Blood. 2021. PMID:33556167 
  6. Rare and de novo coding variants in chromodomain genes in Chiari I malformation. Am J Hum Genet. 2021;108(2):368. PMCID:PMC7895838  PMID:33545031 
  7. Rare and de novo coding variants in chromodomain genes in Chiari I malformation. Am J Hum Genet. 2020. PMID:33352116 
  8. Rare and de novo duplications containing SHOX in clubfoot. J Med Genet. 2020. PMID:32518174 
  9. Prevalence and Impact of Underlying Diagnosis and Comorbidities on Chiari 1 Malformation. Pediatr Neurol. 2020;106:32-37. PMCID:PMC7156318  PMID:32113729 
  10. Obex position is associated with syringomyelia and use of posterior fossa decompression among patients with Chiari I malformation. J Neurosurg Pediatr. 2020;1-8. PMID:32276247 
  11. The Genetics of Idiopathic and Syndromic Clubfoot Journal of Children’s Orthopaedics. 2019;(13):238-244. PMCID:PMC6598048  
  12. How I learned to stop researching and live in the moment Neurology. 2019;92(24):1157-58. doi:https://doi.org/10.1212/WNL.0000000000007656   
  13. Distal chromosome 16p11.2 duplications containing SH2B1 in patients with scoliosis. J Med Genet. 2019;56(7):427-433. PMCID:PMC6592771  PMID:30803986 
  14. A missense variant in SLC39A8 is associated with severe idiopathic scoliosis. Nat Commun. 2018;9(1):4171. PMCID:PMC6177404  PMID:30301978 
  15. The Influence of Paternal Separation, Paternal History of Alcohol Use Disorder Risk, and Early Substance Use on Offspring Educational Attainment by Young Adulthood. J Stud Alcohol Drugs. 2017;78(3):426-434. PMCID:PMC5440366  PMID:28499110 
  16. Genetic and environmental contributions to initiation of cigarette smoking in young African-American and European-American women. Drug Alcohol Depend. 2015;157:54-9. PMCID:PMC4663123  PMID:26482091 
  17. Positive Selection on Loci Associated with Drug and Alcohol Dependence. PLoS One. 2015;10(8):e0134393. PMCID:PMC4536217  PMID:26270548 
  18. Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans. Addiction. 2014;109(5):814-22. PMCID:PMC3984604  PMID:24401102 
  19. Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy. Sci Rep. 2014;4:4497. PMCID:PMC4894386  PMID:24675634 
  20. Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease. PLoS One. 2011;6(2):e15918. PMCID:PMC3036586  PMID:21347408 
  21. Genetic and environmental contributions to variation in baboon cranial morphology. Am J Phys Anthropol. 2010;143(1):1-12. PMCID:PMC3258659  PMID:20623673 
Last updated: 08/30/2021
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