Department of Pediatrics

Education

• BS, California Lutheran University, 2005
• PhD, University of Alabama at Birmingham, 2013

Training

• Post-doctoral Fellow, University of California, Los Angeles, 2013 - 2016
• Post-doctoral Fellow, Washington University in St. Louis, 2016 - 2017

Recent Publications view all (23)

1. van den Brink DP, Kleinveld DJB, Sloos PH, Thomas KA, Stensballe J, Johansson PI, Pati S, Sperry J, Spinella PC, Juffermans NP. Plasma as a resuscitation fluid for volume-depleted shock: Potential benefits and risks. Transfusion. 2021;61 Suppl 1:S301-S312. PMCID:PMC8361764  PMID:34057210 
2. Thomas KA, Shea SM, Spinella PC. Effects of pathogen reduction technology and storage duration on the ability of cryoprecipitate to rescue induced coagulopathies in vitro. Transfusion. 2021. PMID:33755208 
3. Faustino EVS, Shabanova V, Raffini LJ, Kandil SB, Li S, Pinto MG, Cholette JM, Hanson SJ, Nellis ME, Silva CT, Chima R, Sharathkumar A, Thomas KA, McPartland T, Tala JA, Spinella PC, CRETE Trial Investigators and the Pediatric Critical Care Blood Research Network (BloodNet) of the Pediatric Acute Lung Injury and Sepsis Investigators Network (PALISI).. Efficacy of Early Prophylaxis Against Catheter-Associated Thrombosis in Critically Ill Children: A Bayesian Phase 2b Randomized Clinical Trial. Crit Care Med. 2021;49(3):e235-e246. PMCID:PMC7902342  PMID:33372745 
4. Spinella PC, Thomas KA, Turnbull IR, Fuchs A, Bochicchio K, Schuerer D, Reese S, Coleoglou Centeno AA, Horn CB, Baty J, Shea SM, Meledeo MA, Pusateri AE, Levy JH, Cap AP, Bochicchio GV, TAMPITI Investigators.. The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial. Front Immunol. 2020;11:2085. PMCID:PMC7506112  PMID:33013880 
5. Dunlap MD, Prince OA, Rangel-Moreno J, Thomas KA, Scordo JM, Torrelles JB, Cox J, Steyn AJC, Zúñiga J, Kaushal D, Khader SA. Formation of Lung Inducible Bronchus Associated Lymphoid Tissue Is Regulated by Mycobacterium tuberculosis Expressed Determinants. Front Immunol. 2020;11:1325. PMCID:PMC7338767  PMID:32695111 
6. Shea SM, Staudt AM, Thomas KA, Schuerer D, Mielke JE, Folkerts D, Lowder E, Martin C, Bochicchio GV, Spinella PC. The use of low-titer group O whole blood is independently associated with improved survival compared to component therapy in adults with severe traumatic hemorrhage. Transfusion. 2020;60 Suppl 3:S2-S9. PMID:32478896 
7. D'Alessandro A, Thomas KA, Stefanoni D, Gamboni F, Shea SM, Reisz JA, Spinella PC. Metabolic phenotypes of standard and cold-stored platelets. Transfusion. 2020;60 Suppl 3:S96-S106. PMCID:PMC7971209  PMID:31880330 
8. Ahmed M, Thirunavukkarasu S, Rosa BA, Thomas KA, Das S, Rangel-Moreno J, Lu L, Mehra S, Mbandi SK, Thackray LB, Diamond MS, Murphy KM, Means T, Martin J, Kaushal D, Scriba TJ, Mitreva M, Khader SA. Immune correlates of tuberculosis disease and risk translate across species. Sci Transl Med. 2020;12(528). PMCID:PMC7354419  PMID:31996462 
9. Scorer TG, Reddoch-Cardenas KM, Thomas KA, Cap AP, Spinella PC. Therapeutic Utility of Cold-Stored Platelets or Cold-Stored Whole Blood for the Bleeding Hematology-Oncology Patient. Hematol Oncol Clin North Am. 2019;33(5):873-885. PMID:31466610 
10. Muisyo T, Bernardo EO, Camazine M, Colvin R, Thomas KA, Borgman MA, Spinella PC. Mortality prediction in pediatric trauma. J Pediatr Surg. 2019;54(8):1613-1616. PMID:30270118 
11. Shea SM, Thomas KA, Spinella PC. The effect of platelet storage temperature on haemostatic, immune, and endothelial function: potential for personalised medicine. Blood Transfus. 2019;17(4):321-330. PMCID:PMC6683864  PMID:31385802 
12. Rogers SC, Moynihan FT 4th, McDonough R, Timm DD, Hovmand-Warner E, Frazier E, Thomas KA, Spinella PC, Doctor A. Effect of plasma processing and storage on microparticle abundance, nitric oxide scavenging, and vasoactivity. Transfusion. 2019;59(S2):1568-1577. PMID:30980740 
13. Thomas KA, Shea SM, Yazer MH, Spinella PC. Effect of leukoreduction and pathogen reduction on the hemostatic function of whole blood. Transfusion. 2019;59(S2):1539-1548. PMID:30980757 
14. Roux A, Thomas KA, Sage E, Suberbielle-Boissel C, Beaumont-Azuar L, Parquin F, Le Guen M, Harre N, Hamid AM, Reed EF. Donor-specific HLA antibody-mediated complement activation is a significant indicator of antibody-mediated rejection and poor long-term graft outcome during lung transplantation: a single center cohort study. Transpl Int. 2018;31(7):761-772. PMCID:PMC5995657  PMID:29537702 
15. Roux A, Bendib Le Lan I, Holifanjaniaina S, Thomas KA, Picard C, Grenet D, De Miranda S, Douvry B, Beaumont-Azuar L, Sage E, Devaquet J, Cuquemelle E, Le Guen M, Suberbielle C, Gautreau C, Stern M, Rossetti M, Hamid AM, Parquin F. Characteristics of Donor-Specific Antibodies Associated With Antibody-Mediated Rejection in Lung Transplantation. Front Med (Lausanne). 2017;4:155. PMCID:PMC5641623  PMID:29075627 
16. Valenzuela NM, Thomas KA, Mulder A, Parry GC, Panicker S, Reed EF. Complement-Mediated Enhancement of Monocyte Adhesion to Endothelial Cells by HLA Antibodies, and Blockade by a Specific Inhibitor of the Classical Complement Cascade, TNT003. Transplantation. 2017;101(7):1559-1572. PMCID:PMC5482566  PMID:28640789 
17. Butler CL, Valenzuela NM, Thomas KA, Reed EF. Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection. J Immunol Res. 2017;2017:7903471. PMCID:PMC5360970  PMID:28373996 
18. Thomas KA, King RG, Sestero CM, Justement LB. TREM-like transcript 2 is stored in human neutrophil primary granules and is up-regulated in response to inflammatory mediators. J Leukoc Biol. 2016;100(1):177-84. PMCID:PMC6608082  PMID:26753760 
19. Roux A, Bendib Le Lan I, Holifanjaniaina S, Thomas KA, Hamid AM, Picard C, Grenet D, De Miranda S, Douvry B, Beaumont-Azuar L, Sage E, Devaquet J, Cuquemelle E, Le Guen M, Spreafico R, Suberbielle-Boissel C, Stern M, Parquin F, Foch Lung Transplantation Group.. Antibody-Mediated Rejection in Lung Transplantation: Clinical Outcomes and Donor-Specific Antibody Characteristics. Am J Transplant. 2016;16(4):1216-28. PMID:26845386 
20. Thomas KA, Valenzuela NM, Gjertson D, Mulder A, Fishbein MC, Parry GC, Panicker S, Reed EF. An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA. Am J Transplant. 2015;15(8):2037-49. PMCID:PMC4654252  PMID:25904443 
21. Thomas KA, Valenzuela NM, Reed EF. The perfect storm: HLA antibodies, complement, FcγRs, and endothelium in transplant rejection. Trends Mol Med. 2015;21(5):319-29. PMCID:PMC4424065  PMID:25801125 
22. Lan JH, Yin Y, Reed EF, Moua K, Thomas K, Zhang Q. Impact of three Illumina library construction methods on GC bias and HLA genotype calling. Hum Immunol. 2015;76(2-3):166-75. PMCID:PMC5089167  PMID:25543015 
23. Halpert MM, Thomas KA, King RG, Justement LB. TLT2 potentiates neutrophil antibacterial activity and chemotaxis in response to G protein-coupled receptor-mediated signaling. J Immunol. 2011;187(5):2346-55. PMCID:PMC3159717  PMID:21804015