Department of Pediatrics

Clinical Interests

Dr. Bacharier is the Robert C Strunk Endowed Chair for Lung and Respiratory Research, Professor of Pediatrics and Medicine at Washington University School of Medicine, USA Clinical Director of the Division of Pediatric Allergy, Immunology and Pulmonary Medicine, and Unit Co-Leader for the Pediatric Patient Oriented Research Unit. He received his undergraduate degree in biophysics from The Johns Hopkins University, USA and his medical degree from Washington University School of Medicine. Dr. Bacharier was an intern and resident in pediatrics at St. Louis Children's Hospital and a fellow in Pediatric Allergy and Immunology at Children's Hospital, Boston and Harvard Medical School. He was a recipient of the 2005 Samuel R. Goldstein Leadership Award in Medical Student Education from Washington University School of Medicine and is a member of several organizations including the American Academy of Allergy, Asthma and Immunology, the American College of Allergy, Asthma and Immunology, and the American Thoracic Society. Dr. Bacharier's research focuses on childhood asthma. Specifically, he is a Principal Investigator in the NHLBI-funded AsthmaNet, a multi-centered network examining therapeutic approaches to childhood asthma. He is an investigator in the NHLBI’s PrecISE Program for Severe Asthma and the Inner City Asthma Consortium’s URECA study examining the influence of urban environments on the development of asthma and allergic disorders. He is also an Investigator in the American Lung Association’s Asthma Clinical Research Center Network. Dr. Bacharier is also currently investigating the role of early infection with Respiratory Syncytial Virus upon the subsequent development of asthma.

Education

• BA, General and Department Honors, The Johns Hopkins University, 1988
• MD, Washington University School of Medicine, 1992

Training

• Internship and Residency, St. Louis Children's Hospital, 1992 - 1995
• Fellowship , Children's Hospital, Boston and Harvard Medical School , 1995 - 1998

Licensure and Board Certification

• 1993 - PresDiplomate, National Board of Medical Examiners
• 1996 - PresDiplomate, American Board of Pediatrics, Recertified 2002
• 1997 - PresDiplomate, American Board of Allergy and Immunology, Recertified 2006
• 1998 - PresMO, Medical License

Honors and Awards

• Washington University Student Research Fellowship, 1989
• ACAAI Travel Grant, 1996
• The Distinguished Residents and Fellows Asthma Education Program, London, England, 1996
• AAAAI Travel Grant, 1997 and 1998, 1997
• National Institutes of Health Pediatric Research Loan Repayment Award (renewal 2004-6), 2002 - 2004
• Samuel R. Goldstein Leadership Award in Medical Student Education, Washington University School of Medicine, St. Louis, MO, 2005
• Alpha Omega Alpha, Washington University School of Medicine, St. Louis, MO, 2013
• Harvey R. Colten, MD Scholar in Pediatrics, 2015 - 2016

Recent Publications view all (196)

Publication Co-Authors

Gregory A. Storch, M.D.

Todd Druley, M.D., Ph.D.

Caroline C. Horner, M.D.

Mayte Figueroa, MD, FACC

Kristine Wylie, Ph.D.

Richard Buller, Ph.D. D(ABMM)

Maleewan Kitcharoensakkul, MD, MSCI

Andrea Coverstone, M.D.

Mario Castro

Charles Canter, M.D.

Aimée Baumann-Dudenhoeffer, M.D.

Katherine Rivera-Spoljaric, M.D., MSCI

Avraham Beigelman, M.D.

Jane M. Garbutt, M.D.

Ana María Arbeláez, M.D. MSCI

Gordon R. Bloomberg, M.D.

Todd N. Wylie

Christina G. Kwong, MD

Joseph P. Bradley, MD, FACS

S. Celeste Morley, M.D., Ph.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Leonard B. Bacharier, M.D.

1. Wechsler ME, Szefler SJ, Ortega VE, Pongracic JA, Chinchilli V, Lima JJ, Krishnan JA, Kunselman SJ, Mauger D, Bleecker ER, Bacharier LB, Beigelman A, Benson M, Blake KV, Cabana MD, Cardet JC, Castro M, Chmiel JF, Covar R, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Grossman N, Holguin F, Jackson DJ, Kumar H, Kraft M, LaForce CF, Lang J, Lazarus SC, Lemanske RF Jr, Long D, Lugogo N, Martinez F, Meyers DA, Moore WC, Moy J, Naureckas E, Olin JT, Peters SP, Phipatanakul W, Que L, Raissy H, Robison RG, Ross K, Sheehan W, Smith LJ, Solway J, Sorkness CA, Sullivan-Vedder L, Wenzel S, White S, Israel E, NHLBI AsthmaNet.. Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma. N Engl J Med. 2019;381(13):1227-1239. PMID:31553835 
2. Kanchongkittiphon W, Kabil N, Bacharier LB, Kitcharoensakkul M. Ecallantide: An alternative treatment of refractory angioedema in adolescents with systemic lupus erythematosus. J Allergy Clin Immunol Pract. 2019. PMID:31541765 
3. Grossman NL, Ortega VE, King TS, Bleecker ER, Ampleford EA, Bacharier LB, Cabana MD, Cardet JC, Carr TF, Castro M, Denlinger LC, Denson JL, Fandino N, Fitzpatrick AM, Hawkins GA, Holguin F, Krishnan JA, Lazarus SC, Nyenhuis SM, Phipatanakul W, Ramratnam SK, Wenzel S, Peters SP, Meyers DA, Wechsler ME, Israel E. Exacerbation-Prone Asthma in the Context of Race and Ancestry in Asthma Clinical Research Network Trials. J Allergy Clin Immunol. 2019. PMID:31520679 
4. Lee-Sarwar KA, Kelly RS, Lasky-Su J, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Rifas-Shiman SL, Carey VJ, Harshfield BJ, Laranjo N, Gold DR, Weiss ST, Litonjua AA. Fecal short-chain fatty acids in pregnancy and offspring asthma and allergic outcomes. J Allergy Clin Immunol Pract. 2019. PMID:31494295 
5. Mirzakhani H, Carey VJ, McElrath TF, Hollis BW, O'Connor GT, Zeiger RS, Bacharier L, Litonjua AA, Weiss ST. Maternal Asthma, Preeclampsia, and Risk for Childhood Asthma at Age Six. Am J Respir Crit Care Med. 2019;200(5):638-642. PMID:31059286 
6. Lang JE, Bunnell HT, Lima JJ, Hossain MJ, Wysocki T, Bacharier L, Dempsey A, Ulrich L, Test MR, Forrest CB. Effects of age, sex, race/ethnicity, and allergy status in obesity-related pediatric asthma. Pediatr Pulmonol. 2019. PMID:31469258 
7. Bacharier LB, Mori A, Kita H. Advances in Asthma, ACO, and Related Biologics in 2018. J Allergy Clin Immunol. 2019. PMID:31476323 
8. Coverstone AM, Bacharier LB, Wilson BS, Fitzpatrick AM, Teague WG, Phipatanakul W, Wenzel SE, Gaston BM, Bleecker ER, Moore WC, Ramratnam S, Jarjour NN, Ly NP, Fahy JV, Mauger DT, Schechtman KB, Yin-DeClue H, Boomer JS, Castro M. Clinical significance of the bronchodilator response in children with severe asthma. Pediatr Pulmonol. 2019. PMID:31424170 
9. Lee-Sarwar KA, Kelly RS, Lasky-Su J, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Weiss ST, Litonjua AA. Integrative analysis of the intestinal metabolome of childhood asthma. J Allergy Clin Immunol. 2019;144(2):442-454. PMCID:PMC6688902  PMID:30914378 
10. Schulten V, Frazier A, Calatroni A, Kattan M, Bacharier LB, O'Connor GT, Sandel MT, Wood RA, Wheatley LM, Togias A, Visness CM, Dresen A, Gern JE, Sette A. The association of allergic sensitization patterns in early childhood with disease manifestations and immunological reactivity at 10 years of age. Clin Exp Allergy. 2019;49(8):1087-1094. PMID:31046157 
11. Sumino K, Bacharier LB, Taylor J, Chadwick-Mansker K, Curtis V, Nash A, Jackson-Triggs S, Moen J, Schechtman KB, Garbutt J, Castro M. A Pragmatic Trial of Symptom-Based Inhaled Corticosteroid Use in African-American Children with Mild Asthma. J Allergy Clin Immunol Pract. 2019. PMID:31371165 
12. Pomés A, Glesner J, Calatroni A, Visness CM, Wood RA, O'Connor GT, Kattan M, Bacharier LB, Wheatley LM, Gern JE, Busse WW, National Institute of Allergy and Infectious Diseases–funded Inner-City Asthma Consortium.. Cockroach allergen component analysis of children with or without asthma and rhinitis in an inner-city birth cohort. J Allergy Clin Immunol. 2019. PMID:31201891 
13. Gern JE, Jackson DJ, Lemanske RF Jr, Seroogy CM, Tachinardi U, Craven M, Hwang SY, Hamilton CM, Huggins W, O'Connor GT, Gold DR, Miller R, Kattan M, Johnson CC, Ownby D, Zoratti EM, Wood RA, Visness CM, Martinez F, Wright A, Lynch S, Ober C, Khurana Hershey GK, Ryan P, Hartert T, Bacharier LB. The Children's Respiratory and Environmental Workgroup (CREW) birth cohort consortium: design, methods, and study population. Respir Res. 2019;20(1):115. PMCID:PMC6558735  PMID:31182091 
14. Reddel HK, FitzGerald JM, Bateman ED, Bacharier LB, Becker A, Brusselle G, Buhl R, Cruz AA, Fleming L, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Pedersen SE, Sheikh A, Yorgancioglu A, Boulet LP. GINA 2019: a fundamental change in asthma management: Treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents. Eur Respir J. 2019;53(6). PMID:31249014 
15. Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour NN, Larkin A, Levy BD, Ly NP, Ortega VE, Peters SP, Phipatanakul W, Ramratnam S, Teague WG. Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol. 2019;143(6):2052-2061. PMCID:PMC6556425  PMID:30635198 
16. Lazarus SC, Krishnan JA, King TS, Lang JE, Blake KV, Covar R, Lugogo N, Wenzel S, Chinchilli VM, Mauger DT, Dyer AM, Boushey HA, Fahy JV, Woodruff PG, Bacharier LB, Cabana MD, Cardet JC, Castro M, Chmiel J, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Hastie A, Holguin F, Israel E, Jackson D, Kraft M, LaForce C, Lemanske RF Jr, Martinez FD, Moore W, Morgan WJ, Moy JN, Myers R, Peters SP, Phipatanakul W, Pongracic JA, Que L, Ross K, Smith L, Szefler SJ, Wechsler ME, Sorkness CA, National Heart, Lung, and Blood Institute AsthmaNet.. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019;380(21):2009-2019. PMCID:PMC6711475  PMID:31112384 
17. Wheatley LM, Wood R, Nadeau K, Liu A, Zoratti E, Bacharier L, Brittain E, Calderon M, Casale T, Chipps B, Cox L, Creticos PS, Desai M, Dreborg S, Durham S, Gergen PJ, Gruchalla R, Nelson H, O'Hehir RE, Plaut M, Schwaninger JM, Tilles S, Vickery B, Wittenberg KM, Togias A. Mind the gaps: Clinical trial concepts to address unanswered questions in aeroallergen immunotherapy-An NIAID/AHRQ Workshop. J Allergy Clin Immunol. 2019;143(5):1711-1726. PMID:30731123 
18. Altman MC, Gill MA, Whalen E, Babineau DC, Shao B, Liu AH, Jepson B, Gruchalla RS, O'Connor GT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Zoratti EM, Johnson CC, Teach SJ, Kattan M, Bacharier LB, Beigelman A, Sigelman SM, Presnell S, Gern JE, Gergen PJ, Wheatley LM, Togias A, Busse WW, Jackson DJ. Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children. Nat Immunol. 2019;20(5):637-651. PMCID:PMC6472965  PMID:30962590 
19. Kitcharoensakkul M, Kau AL, Bacharier LB, Goss CW, Beigelman A. Using only a subset of pneumococcal serotypes is reliable for the diagnosis of specific antibody deficiency in children: A proof-of-concept study. Pediatr Allergy Immunol. 2019;30(3):392-395. PMCID:PMC6488433  PMID:30681739 
20. Guilbert TW, Bacharier LB, Mauger DT, Phipatanakul W, Szefler SJ, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana MD, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin JT, Peters SP, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Teague WG, Thyne S, Martinez FD, National Heart, Lung, and Blood Institute's AsthmaNet.. Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. J Allergy Clin Immunol. 2019;143(5):1934-1937.e4. PMCID:PMC6504562  PMID:30660645 
21. Mirzakhani H, Carey VJ, Zeiger R, Bacharier LB, O'Connor GT, Schatz MX, Laranjo N, Weiss ST, Litonjua AA. Impact of parental asthma, prenatal maternal asthma control, and vitamin D status on risk of asthma and recurrent wheeze in 3-year-old children. Clin Exp Allergy. 2019;49(4):419-429. PMCID:PMC6438751  PMID:30461089 
22. Cardet JC, Codispoti CD, King TS, Bacharier L, Carr T, Castro M, Chinchilli V, Dunn R, Holquing F, Engle L, Nelson K, Ortega VE, Peters M, Ramratnam S, Krishnan JA, Wechsler ME, Israel E, National Heart, Lung, and Blood Institute Asthmanet.. Predictors of inhaled corticosteroid taper failure in adults with asthma. J Allergy Clin Immunol Pract. 2019;7(4):1335-1337.e3. PMCID:PMC6424637  PMID:30240889 
23. Glesner J, Filep S, Vailes LD, Wünschmann S, Chapman MD, Birrueta G, Frazier A, Jeong KY, Schal C, Bacharier L, Beigelman A, Busse P, Schulten V, Sette A, Pomés A. Allergen content in German cockroach extracts and sensitization profiles to a new expanded set of cockroach allergens determine in vitro extract potency for IgE reactivity. J Allergy Clin Immunol. 2019;143(4):1474-1481.e8. PMCID:PMC6395535  PMID:30170124 
24. Karvonen AM, Sordillo JE, Gold DR, Bacharier LB, O'Connor GT, Zeiger RS, Beigelman A, Weiss ST, Litonjua AA. Gut microbiota and overweight in 3-year old children. Int J Obes (Lond). 2019;43(4):713-723. PMCID:PMC6457121  PMID:30568265 
25. Kwong CG, Bacharier LB. Phenotypes of wheezing and asthma in preschool children. Curr Opin Allergy Clin Immunol. 2019;19(2):148-153. PMCID:PMC6395501  PMID:30640211 
26. Chipps BE, Bacharier LB, Murphy KR, Lang D, Farrar JR, Rank M, Oppenheimer J, Zeiger RS. The Asthma Controller Step-down Yardstick. Ann Allergy Asthma Immunol. 2019;122(3):241-262.e4. PMID:30550809 
27. Togias A, Gergen PJ, Hu JW, Babineau DC, Wood RA, Cohen RT, Makhija MM, Khurana Hershey GK, Kercsmar CM, Gruchalla RS, Liu AH, Wang E, Kim H, Lamm CI, Bacharier LB, Pillai D, Sigelman SM, Gern JE, Busse WW. Rhinitis in children and adolescents with asthma: Ubiquitous, difficult to control, and associated with asthma outcomes. J Allergy Clin Immunol. 2019;143(3):1003-1011.e10. PMCID:PMC6408960  PMID:30213627 
28. Sordillo JE, Korrick S, Laranjo N, Carey V, Weinstock GM, Gold DR, O'Connor G, Sandel M, Bacharier LB, Beigelman A, Zeiger R, Litonjua AA, Weiss ST. Association of the Infant Gut Microbiome With Early Childhood Neurodevelopmental Outcomes: An Ancillary Study to the VDAART Randomized Clinical Trial. JAMA Netw Open. 2019;2(3):e190905. PMCID:PMC6583279  PMID:30901046 
29. Fitzpatrick AM, Bacharier LB, Guilbert TW, Jackson DJ, Szefler SJ, Beigelman A, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Zeiger RS, Mauger DT, NIH/NHLBI AsthmaNet.. Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation. J Allergy Clin Immunol Pract. 2019;7(3):915-924.e7. PMCID:PMC6401237  PMID:30267890 
30. Birrueta G, Frazier A, Pomés A, Glesner J, Filep S, Schal C, Jeong KY, McMurtrey C, Vander Schans T, Hildebrand WH, Busse P, Beigelman A, Bacharier LB, Peters B, Sette A, Schulten V. Variability in German Cockroach Extract Composition Greatly Impacts T Cell Potency in Cockroach-Allergic Donors. Front Immunol. 2019;10:313. PMCID:PMC6413722  PMID:30891032 
31. Lee-Sarwar K, Kelly RS, Lasky-Su J, Kachroo P, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Weiss ST, Litonjua AA. Dietary and Plasma Polyunsaturated Fatty Acids Are Inversely Associated with Asthma and Atopy in Early Childhood. J Allergy Clin Immunol Pract. 2019;7(2):529-538.e8. PMCID:PMC6400588  PMID:30145365 
32. Bacharier LB, Beigelman A, Calatroni A, Jackson DJ, Gergen PJ, O'Connor GT, Kattan M, Wood RA, Sandel MT, Lynch SV, Fujimura KE, Fadrosh DW, Santee CA, Boushey H, Visness CM, Gern JE, NIAID sponsored Inner-City Asthma Consortium.. Longitudinal Phenotypes of Respiratory Health in a High-Risk Urban Birth Cohort. Am J Respir Crit Care Med. 2019;199(1):71-82. PMCID:PMC6353010  PMID:30079758 
33. Mirzakhani H, Carey VJ, McElrath TF, Qiu W, Hollis BW, O'Connor GT, Zeiger RS, Bacharier L, Litonjua AA, Weiss ST. Impact of Preeclampsia on the Relationship between Maternal Asthma and Offspring Asthma. An Observation from the VDAART Clinical Trial. Am J Respir Crit Care Med. 2019;199(1):32-42. PMCID:PMC6353019  PMID:30153046 
34. Krings JG, McGregor MC, Bacharier LB, Castro M. Biologics for Severe Asthma: Treatment-Specific Effects Are Important in Choosing a Specific Agent. J Allergy Clin Immunol Pract. 2019;7(5):1379-1392. PMID:31076056 
35. Savage JH, Lee-Sarwar KA, Sordillo JE, Lange NE, Zhou Y, O'Connor GT, Sandel M, Bacharier LB, Zeiger R, Sodergren E, Weinstock GM, Gold DR, Weiss ST, Litonjua AA. Diet during Pregnancy and Infancy and the Infant Intestinal Microbiome. J Pediatr. 2018;203:47-54.e4. PMCID:PMC6371799  PMID:30173873 
36. Lang JE, Bunnell HT, Hossain MJ, Wysocki T, Lima JJ, Finkel TH, Bacharier L, Dempsey A, Sarzynski L, Test M, Forrest CB. Being Overweight or Obese and the Development of Asthma. Pediatrics. 2018;142(6). PMID:30478238 
37. Lee-Sarwar K, Kelly RS, Lasky-Su J, Moody DB, Mola AR, Cheng TY, Comstock LE, Zeiger RS, O'Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Bunyavanich S, Savage JH, Weiss ST, Brennan PJ, Litonjua AA. Intestinal microbial-derived sphingolipids are inversely associated with childhood food allergy. J Allergy Clin Immunol. 2018;142(1):335-338.e9. PMID:29729303 
38. Coverstone AM, Wilson B, Burgdorf D, Schechtman KB, Storch GA, Holtzman MJ, Castro M, Bacharier LB, Sumino K. Recurrent wheezing in children following human metapneumovirus infection. J Allergy Clin Immunol. 2018;142(1):297-301.e2. PMID:29481834 
39. Lee-Sarwar K, Hauser R, Calafat AM, Ye X, O'Connor GT, Sandel M, Bacharier LB, Zeiger RS, Laranjo N, Gold DR, Weiss ST, Litonjua AA, Savage JH. Prenatal and early-life triclosan and paraben exposure and allergic outcomes. J Allergy Clin Immunol. 2018;142(1):269-278.e15. PMCID:PMC5924494  PMID:29111213 
40. Bacharier LB, Covar RA, Haselkorn T, Iqbal A, Alvarez C, Mink DR, Chen H, Zeiger RS. Consistently very poorly controlled asthma is associated with greater activity and school impairment in children with severe or difficult-to-treat asthma. J Allergy Clin Immunol Pract. 2018. PMID:29883753 
41. Chipps BE, Bacharier LB, Farrar JR, Jackson DJ, Murphy KR, Phipatanakul W, Szefler SJ, Teague WG, Zeiger RS. The pediatric asthma yardstick: Practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma. Ann Allergy Asthma Immunol. 2018;120(6):559-579.e11. PMID:29653238 
42. Jackson DJ, Bacharier LB, Lemanske RF Jr. Inhaled Glucocorticoids in Asthma. N Engl J Med. 2018;378(21):2051. PMID:29791825 
43. Krishnan S, Dozor AJ, Bacharier L, Lang JE, Irvin CG, Kaminsky D, Farber HJ, Gerald L, Brown M, Holbrook JT, Wise RA, Ryu J, Bose S, Yasin R, Saams J, Henderson RJ, Teague WG, American Lung Association Airway Clinical Research Centers (ALA-ACRC) Network.. Clinical characterization of children with resistant airflow obstruction, a multicenter study. J Asthma. 2018;1-7. PMID:29771599 
44. DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague W. Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. BMC Pulm Med. 2018;18(1):58. PMCID:PMC5891903  PMID:29631584 
45. O'Connor GT, Lynch SV, Bloomberg GR, Kattan M, Wood RA, Gergen PJ, Jaffee KF, Calatroni A, Bacharier LB, Beigelman A, Sandel MT, Johnson CC, Faruqi A, Santee C, Fujimura KE, Fadrosh D, Boushey H, Visness CM, Gern JE. Early-life home environment and risk of asthma among inner-city children. J Allergy Clin Immunol. 2018;141(4):1468-1475. PMID:28939248 
46. Dy T, Lewis EM, Murugan V, Gehlert S, Taylor J, Garbutt J, Bacharier LB, Castro M, Sumino K. Caregiver and pediatric provider perspectives on symptom-based inhaled corticosteroid therapy in asthma. Respir Med. 2018;137:201-205. PMID:29605205 
47. Lang JE, Fitzpatrick AM, Mauger DT, Guilbert TW, Jackson DJ, Lemanske RF Jr, Martinez FD, Strunk RC, Zeiger RS, Phipatanakul W, Bacharier LB, Pongracic JA, Holguin F, Cabana MD, Covar RA, Raissy HH, Tang M, Szefler SJ, National Institutes of Health/National Heart, Lung and Blood Institute AsthmaNet.. Overweight/obesity status in preschool children associates with worse asthma but robust improvement on inhaled corticosteroids. J Allergy Clin Immunol. 2018;141(4):1459-1467.e2. PMID:29273557 
48. Chandra S, Wingender G, Greenbaum JA, Khurana A, Gholami AM, Ganesan AP, Rosenbach M, Jaffee K, Gern JE, Wood R, O'Connor G, Sandel M, Kattan M, Bacharier L, Togias A, Horner AA, Kronenberg M. Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment. J Immunol. 2018;200(6):1995-2003. PMCID:PMC5840005  PMID:29431692 
49. Jackson DJ, Bacharier LB, Mauger DT, Boehmer S, Beigelman A, Chmiel JF, Fitzpatrick AM, Gaffin JM, Morgan WJ, Peters SP, Phipatanakul W, Sheehan WJ, Cabana MD, Holguin F, Martinez FD, Pongracic JA, Baxi SN, Benson M, Blake K, Covar R, Gentile DA, Israel E, Krishnan JA, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Long D, Ly N, Marbin J, Moy JN, Myers RE, Olin JT, Raissy HH, Robison RG, Ross K, Sorkness CA, Lemanske RF Jr, National Heart, Lung, and Blood Institute AsthmaNet.. Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations. N Engl J Med. 2018;378(10):891-901. PMCID:PMC5972517  PMID:29504498 
50. Altman MC, Whalen E, Togias A, O'Connor GT, Bacharier LB, Bloomberg GR, Kattan M, Wood RA, Presnell S, LeBeau P, Jaffee K, Visness CM, Busse WW, Gern JE. Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma. J Allergy Clin Immunol. 2018. PMID:29518416 
51. Kattan M, Bacharier LB, O'Connor GT, Cohen R, Sorkness RL, Morgan W, Gergen PJ, Jaffee KF, Visness CM, Wood RA, Bloomberg GR, Doyle S, Burton R, Gern JE. Spirometry and Impulse Oscillometry in Preschool Children: Acceptability and Relationship to Maternal Smoking in Pregnancy. J Allergy Clin Immunol Pract. 2018. PMID:29449165 
52. Willen SM, Rodeghier M, Strunk RC, Bacharier LB, Rosen CL, Kirkham FJ, DeBaun MR, Cohen RT. Aeroallergen sensitization predicts acute chest syndrome in children with sickle cell anaemia. Br J Haematol. 2018;180(4):571-577. PMCID:PMC5945280  PMID:29363738 
53. Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN. Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract. 2018;6(2):545-554.e4. PMCID:PMC5832534  PMID:28866107 
54. Mirzakhani H, Carey VJ, McElrath TF, Laranjo N, O'Connor G, Iverson RE, Lee-Parritz A, Strunk RC, Bacharier LB, Macones GA, Zeiger RS, Schatz M, Hollis BW, Litonjua AA, Weiss ST. The Association of Maternal Asthma and Early Pregnancy Vitamin D with Risk of Preeclampsia: An Observation From Vitamin D Antenatal Asthma Reduction Trial (VDAART). J Allergy Clin Immunol Pract. 2018;6(2):600-608.e2. PMCID:PMC5843492  PMID:28923490 
55. Rota AP, Bacharier LB, Jaffee K, Visness CM, Kattan M, O'Connor GT, Wood RA, Gergen PJ, Gern JE, Bloomberg GR. Screen Time Engagement Is Increased in Urban Children With Asthma. Clin Pediatr (Phila). 2017;56(11):1048-1053. PMID:28871879 
56. Ramratnam SK, Bacharier LB, Guilbert TW. Severe Asthma in Children J Allergy Clin Immunol Pract. 2017;5(4):889-898. doi:10.1016/j.jaip.2017.04.031  PMID:28689839 
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59. Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel E, Severe Asthma Research Program. Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma. Am J Respir Crit Care Med. 2017;195(11):1439-1448. PMCID:PMC5470749  PMID:27967215 
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61. Ehlers A, Xie W, Agapov E, Brown S, Steinberg D, Tidwell R, Sajol G, Schutz R, Weaver R, Yu H, Castro M, Bacharier LB, Wang X, Holtzman MJ, Haspel JA. BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes. Mucosal Immunol. 2017. PMID:28401936 
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65. Bacharier LB. Reducing Exposure to Mouse Allergen Among Children and Adolescents With Asthma Is Achievable, but Is It Enough? JAMA. 2017;317(10):1023-1025. PMID:28264092 
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