Department of Pediatrics

Clinical Interests

Dr. Goldsmith is an Assistant Professor of Pediatrics and Genetics, He is an attending physician in the Division of Critical Care Medicine and a member of the Developmental Biology and Genetics Unit. Dr. Goldsmith received his medical degree from the University of Toronto. He did his residency and fellowship at Washington University School of Medicine and Saint Louis Children's Hospital. Dr. Goldsmith joined the faculty of the Department of Pediatrics at Washington University School of Medicine in 2002. He is board certified in pediatrics and in pediatric critical care medicine. He is a member of the Society for Critical Care Medicine.

Education

• BSc, University of Toronto, 1987
• MSc, University of Toronto, 1990
• MD, University of Toronto, 1995

Training

• Resident, Pediatrics, St. Louis Children's Hospital, 1995 - 1998
• Chief Resident, Pediatrics, St. Louis Children's Hospital, 1998 - 1999
• Fellow, Pediatric Critical Care Medicine, Washington University School of Medicine/St. Louis Children's Hospital, 1999 - 2002
• Solutions for Patient Safety, St. Louis Children's Hospital, 2014
• Program for Leading Innovation in Healthcare and Education, Harvard Macy Institute, 2015
• Lean Leader Training, St. Louis Children's Hospital, 2015
• Academic Medical Leadership Program for Physicians and Scientists, Washington University School of Medicine/Olin Business School/BJC Healthcare, 2017
• Leadership Development for Physicians in Academic Health Centers, Harvard T.H. Chan School of Public Health, 2017

Licensure and Board Certification

• 1996 - PresMO
• 1999 - 2016Pediatrics
• 2002 - PresPediatric Critical Care
• 2014 - PresAdvanced Cardiac Life Support
• 2014 - PresBasic Life Support
• 2014 - PresPediatric Advanced Life Support
• 2017 - PresPediatric Advanced Life Support Instructor

Honors and Awards

• Ann Shepard Memorial Scholarship for Biology, 1986
• Daniel Wilson Scholarship for Physiology/Biochemistry, 1986
• Margaret J. Santalo Memorial Scholarship for Physiology, 1987
• NSERC Summer Research Scholarship, 1987
• University of Toronto Open Graduate Fellowship, 1988 - 1989
• Ontario Graduate Scholarship, 1988 - 1990
• MRC (Canada) Studentship, 1989 - 1990
• Dr. R.E. Haist Award in Physiology, 1991 - 1992
• Dean's Honor Roll in Medicine, 1991 - 1995
• Dr. C.S. Wainwright Memorial Scholarship, 1992
• Robert and Annie McDonnell Trust Fund Research Scholarship, 1992
• MDS Scholarship in Laboratory Medicine, 1993
• MRC (Canada) Summer Research Scholarship, 1993
• Alpha Omega Alpha Honor Medical Society, 1994
• Dr. Carl Witus Prize in Pediatrics, 1994
• Merck Sharp and Dohme Award, 1994
• Cody Gold Medal (graduated 1st overall, School of Medicine, class of 1995), 1995
• Ellen Mickle Fellowship, 1995
• Pediatric Scientist Development Award, 2000 - 2003
• HHMI Young Investigator Award, 2000 - 2004
• Mallinckrodt Foundation Award, 2003 - 2006
• Clinical Nutrition Research Unit Award, 2004 - 2005
• Scholar of the Child Health Research Center of Excellence in Developmental Biology, 2004 - 2006
• James Sutherland Award for Outstanding Research by a Young Investigator, 2006
• Best Doctors in St. Louis, 2007 - Pres
• Best Doctors in America, 2007 - Pres
• Elected to Society for Pediatric Research, 2010
• Faculty Member, F1000, 2019
• Doctor Honoris Causa, Riga Stradins University, 2019

Recent Publications view all (12)

Publication Co-Authors

Todd Druley, M.D., Ph.D.

Laura Schuettpelz, M.D, Ph.D.

S. Paul Hmiel, M.D., Ph.D.

Dennis J. Dietzen, Ph.D.

Ahmed, Said, M.D., Ph.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Matthew I. Goldsmith, M.D.

1. Buchan JG, Gray RS, Gansner JM, Alvarado DM, Burgert L, Gitlin JD, Gurnett CA, Goldsmith MI. Kinesin family member 6 (kif6) is necessary for spine development in zebrafish. Dev Dyn. 2014;243(12):1646-57. doi:10.1002/dvdy.24208  PMID:25283277 
2. Said A, Hmiel P, Goldsmith MI, Dietzen D, Hartman ME. Successful use of plasma exchange for profound hemolysis in a child with loxoscelism. Pediatrics. 2014;134(5):e1464-7. doi:10.1542/peds.2013-3338  PMID:25349320 
3. Ha K, Buchan JG, Alvarado DM, McCall K, Vydyanath A, Luther PK, Goldsmith MI, Dobbs MB, Gurnett CA. MYBPC1 mutations impair skeletal muscle function in zebrafish models of arthrogryposis. Hum Mol Genet. 2013;22(24):4967-77. doi:10.1093/hmg/ddt344  PMCID:PMC3836476  PMID:23873045 
4. Oppedal D, Goldsmith MI. A chemical screen to identify novel inhibitors of fin regeneration in zebrafish. Zebrafish. 2010;7(1):53-60. doi:10.1089/zeb.2009.0633  PMCID:PMC2946367  PMID:20384483 
5. Schuettpelz LG, Behrens D, Goldsmith MI, Druley TE. Severe ceftriaxone-induced hemolysis complicated by diffuse cerebral ischemia in a child with sickle cell disease. J Pediatr Hematol Oncol. 2009;31(11):870-2. doi:10.1097/MPH.0b013e3181b7eda2  PMID:19829151 
6. Green J, Taylor JJ, Hindes A, Johnson SL, Goldsmith MI. A gain of function mutation causing skeletal overgrowth in the rapunzel mutant. Dev Biol. 2009;334(1):224-34. doi:10.1016/j.ydbio.2009.07.025  PMCID:PMC2756807  PMID:19632218 
7. Goldsmith MI, Iovine MK, O'Reilly-Pol T, Johnson SL. A developmental transition in growth control during zebrafish caudal fin development. Dev Biol. 2006;296(2):450-7. doi:10.1016/j.ydbio.2006.06.010  PMID:16844108 
8. Goldsmith MI, Fisher S, Waterman R, Johnson SL. Saltatory control of isometric growth in the zebrafish caudal fin is disrupted in long fin and rapunzel mutants. Dev Biol. 2003;259(2):303-17. PMID:12871703 
9. Goldsmith M, Yarbrough L, van der Kooy D. Mechanics of motility: distinct dynein binding domains on alpha- and beta-tubulin. Biochem Cell Biol. 1995;73(9-10):665-71. PMID:8714687 
10. Goldsmith M, Leyland S, Connolly JA, van der Kooy D. A unique tubulin antiserum attenuates the rate of poleward chromosome movement in anaphase. Eur J Cell Biol. 1992;58(2):346-55. PMID:1425771 
11. Goldsmith M, Connolly JA, Kumar N, Wu J, Yarbrough LR, van der Kooy D. Conserved beta-tubulin binding domain for the microtubule-associated motors underlying sperm motility and fast axonal transport. Cell Motil Cytoskeleton. 1991;20(3):249-62. doi:10.1002/cm.970200308  PMID:1723030 
12. Goldsmith M, van der Kooy D. Separate non-cholinergic descending projections and cholinergic ascending projections from the nucleus tegmenti pedunculopontinus. Brain Res. 1988;445(2):386-91. PMID:2453253