Department of Pediatrics

Clinical Interests

Dr. Horner is a member of the Division of Allergy, Immunology and Pulmonary Medicine. She received her undergraduate degree in chemistry from Washington University. She received her medical degree from and completed a residency in Internal Medicine and Pediatrics at St. Louis University. She completed her Allergy/Immunology fellowship at the University of Texas Medical Branch in Galveston, TX. She joined the faculty of Washington University in 2006. She is board certified in Pediatrics, Internal Medicine, and Allergy and Clinical Immunology. Dr. Horner’s research interests include childhood asthma. She has held several leadership positions within the American Academy of Allergy, Asthma, & Immunology (AAAAI) and is a member of the Joint Task Force on Practice Parameters. She currently serves as the fellowship program director for Pediatric Allergy Immunology.

Education

• BA, universali cum honore, Washington University, 1993
• MD, cum laude, St. Louis University School of Medicine, 2000
• MSCI, Washington University School of Medicine, 2011

Training

• Medical Research Technician, Washington University School of Medicine and St. Louis University, 1994 - 1996
• Summer Research Fellow, St. Louis University School of Medicine, 1997 - 1997
• Resident, Internal Medicine & Pediatrics, St. Louis University School of Medicine, 2000 - 2004
• Fellow, Allergy & Immunology, University of Texas Medical Branch, 2004 - 2006

Licensure and Board Certification

• 2004 - PresAmerican Board of Internal Medicine
• 2004 - PresAmerican Board of Pediatrics
• 2006 - PresAmerican Board of Allergy and Immunology
• 2006 - PresMO, Medical License
• 2021 - PresIL Medical License

Honors and Awards

• Medical School Class President, St. Louis University School of Medicine, 1998 - 2000
• Alpha Omega Alpha, St. Louis University School of Medicine, 1999
• Alpha Sigma Nu, National Jesuit honor society, St. Louis University School of Medicine, 1999
• Merck Book Award, awarded for “significant contributions to the welfare of St. Louis University School of Medicine, its students, and its academic program”, 2000
• Academic Fellowship Award, University of Texas Medical Branch, 2005
• Nominee Outstanding Resident/Fellow Award, University of Texas Medical Branch, 2005
• Nominee Outstanding Resident/Fellow Award, University of Texas Medical Branch, 2006
• Clinical Research Training Center Postdoctoral Program Scholar, Washington University School of Medicine, 2008 - 2011
• Gail G Shapiro Clinical Faculty Award, Allergy, Asthma & Immunology Education and Research Trust, American Academy of Allergy, Asthma & Immunology, 2010
• NIH Loan Repayment Program Recipient, 2011 - 2014
• Best Doctors in America® 2019 - 2020 List, 2019
• Best Doctors in America® 2020 - 2021 List, 2020
• Top Doctor, Castle Connolly Top Doctors®, 2021
• Top Doctor, Castle Connolly Top Doctors®, 2022

Recent Publications view all (18)

Publication Co-Authors

Katherine Rivera-Spoljaric, M.D., MSCI

Avraham Beigelman, M.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Caroline C. Horner, M.D.

1. Mantravadi V, Bednarski J, Ritter M, Gu H, Kolicheski A, Horner C, Cooper M, Kitcharoensakkul M. Immunological findings and clinical outcomes of infants with positive newborn screening for severe combined immunodeficiency from a tertiary care center in the U.S. Frontiers in Immunology. 2021. doi:doi: 10.3389/fimmu.2021.734096  
2. Greenhawt M, Abrams EM, Shaker M, Chu DK, Kahn D, Akin C, Alqurashi W, Arkwright P, Baldwin JL, Ben-Shoshan M, Bernstein J, Bingeman T, Blumchen K, Byrne A, Bognanni A, Campbell D, Campbell R, Chagla Z, Chan ES, Chan J, Comberiatti P, Dribin T, Ellis AK, Fleischer D, Fox A, Frischmeyer-Guerrerio P, Gagnon R, Grayson MH, Horner CC, Hourihane J, Katelaris C, Kim H, Kelso J, Lang D, Ledford D, Levin M, Lieberman J, Loh R, Mack D, Mazer B, Mosnaim G, Munblit D, Mustafa S, Nanda A, Oppenheimer J, Perrett KP, Ramsey A, Rank M, Robertson K, Shiek J, Spergel JM, Stukus D, Tang M, Tracy JM, Turner PJ, Whalen-Browne A, Wallace D, Wang J, Wasserman S, Witty JK, Worm M, Vander Leek TK, Golden DBK. . The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and RecommendedEvaluation and Management: A Systematic Review, Meta-analysis, GRADE Assessment, and International Consensus Approach. J Allergy Clin Immunol Pract. 2021;Jun 18;S2213-2198(21)00671-1. doi:https://doi.org/10.1016/j.jaip.2021.06.006  PMID:34153517 
3. Greenhawt M, Shaker M, Wang J, Oppenheimer JJ, Sicherer S, Keet C, Swaggart K, Rank M, Portnoy JM, Bernstein J, Chu DK, Dinakar C, Golden D, Horner C, Lang DM, Lang ES, Khan DA, Lieberman J, Stukus D, Wallace D. Peanut Allergy Diagnosis- a 2020 Practice Parameter Update, Systematic Review, and GRADE Analysis J Allergy Clin Immunol. 2020;S0091-6749(20):31137-4. doi:10.1016/j.jaci.2020.07.031  PMID:32810515 
4. Dykewicz MS, Wallace DV, Amrol DJ, Baroody FM, Bernstein JA, Craig TJ, Dinakar C, Ellis AK, Finegold I, Golden DB, Greenhawt MJ, Hagan JB, Horner CC, Khan DA, Lang DM, Larenas-Linnemann DE, Lieberman JA, Meltzer EO, Oppenheimer JJ, Rank MA, Shaker MS, Shaw JL, Steven GC, Stukus DR, Wang J. Rhinitis 2020: A Practice Parameter Update J Allergy Clin Immunol. 2020;S0091-6749(20):31023-X. doi:10.1016/j.jaci.2020.07.007  PMID:32707227 
5. Shaker MS, Oppenheimer J, Wallace DV, Golden DBK, Lang DM; Joint Task Force for Allergy Practice Parameters; Contributors, Lang ES, Bernstein JA, Campbell RL, Chu D, Dinakar C, Ellis AK, Greenhawt M, Horner C, Lieberman JA, Rank MA, Stukus DR, Wang J. . Making the GRADE in anaphylaxis management: Toward recommendations integrating values, preferences, context, and shared decision making. Ann Allergy Asthma Immunol. 2020;124(6):526-535. doi:10.1016/j.anai.2020.03.009  PMID:32199979  
6. Shaker MS, Wallace DV, Golden DBK, Oppenheimer J, Bernstein JA, Campbell RL, Dinakar C, Ellis A, Greenhawt M, Khan DA, Lang DM, Lang ES, Lieberman JA, Portnoy J, Rank MA, Stukus DR, Wang J; Collaborators, Riblet N, Bobrownicki AMP, Bontrager T, Dusin J, Foley J, Frederick B, Fregene E, Hellerstedt S, Hassan F, Hess K, Horner C, Huntington K, Kasireddy P, Keeler D, Kim B, Lieberman P, Lindhorst E, McEnany F, Milbank J, Murphy H, Pando O, Patel AK, Ratliff N, Rhodes R, Robertson K, Scott H, Snell A, Sullivan R, Trivedi V, Wickham A; Chief Editors, Shaker MS, Wallace DV; Workgroup Contributors, Shaker MS, Wallace DV, Bernstein JA, Campbell RL, Dinakar C, Ellis A, Golden DBK, Greenhawt M, Lieberman JA, Rank MA, Stukus DR, Wang J; Joint Task Force on Practice Parameters Reviewers, Shaker MS, Wallace DV, Golden DBK, Bernstein JA, Dinakar C, Ellis A, Greenhawt M, Horner C, Khan DA, Lieberman JA, Oppenheimer J, Rank MA, Shaker MS, Stukus DR, Wang J. Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis. J Allergy Clin Immunol. 2020;145(4):1082-1123. doi:10.1016/j.jaci.2020.01.017  
7. Guilbert TW, Bacharier LB, Mauger DT, Phipatanakul W, Szefler SJ, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana MD, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin JT, Peters SP, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Teague WG, Thyne S, Martinez FD;(Collaborator National Heart, Lung, and Blood Institute's AsthmaNet: Horner C). Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. J Allergy Clin Immunol. 2019;143(5):1934-1937. doi:10.1016/j.jaci.2018.10.071  PMID:30660645 
8. Jackson DJ, Bacharier LB, Mauger DT, Boehmer S, Beigelman A, Chmiel JF, Fitzpatrick AM, Gaffin JM, Morgan WJ, Peters SP, Phipatanakul W, Sheehan WJ, Cabana MD, Holguin F, Martinez FD, Pongracic JA, Baxi SN, Benson M, Blake K, Covar R, Gentile DA, Israel E, Krishnan JA, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Long D, Ly N, Marbin J, Moy JN, Myers RE, Olin JT, Raissy HH, Robison RG, Ross K, Sorkness CA, Lemanske RF Jr; (Collaborator National Heart, Lung, and Blood Institute AsthmaNet: Horner C). Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations. N Engl J Med. 2018;378(10):891-901. doi:10.1056/NEJMoa1710988  PMID:29504498  
9. Greenhawt M, Turner PJ, Kelso JM. (Joint Task Force on Practice Parameter Member: Horner C). Administration of influenza vaccines to egg allergic recipients: A practice parameter update 2017. Ann Allergy Asthma Immunol. 2018;120(1):49-52. doi:10.1016/j.anai.2017.10.020  PMID:29273128 
10. Dykewicz MS, Wallace DV, Baroody F, Bernstein J, Craig T, Finegold I, Huang F, Larenas-Linnemann D, Meltzer E, Steven G, Bernstein DI, Blessing-Moore J, Dinakar C, Greenhawt M, Horner CC, Khan DA, Lang D, Oppenheimer J, Portnoy JM, Randolph CR, Rank MA, Workgroup Chair and Cochair., Dykewicz MS, Wallace DV. Treatment of seasonal allergic rhinitis: An evidence-based focused 2017 guideline update. Ann Allergy Asthma Immunol. 2017;119(6):489-511.e41. PMID:29103802 
11. Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W; (Collaborator NIH/NHLBI AsthmaNet: Horner C). Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016;375(7):619-30. doi:10.1056/NEJMoa1515990  PMID:27532828  
12. Horner CC, Dula C, Bacharier LB, Garbutt JM, Gonzalez C, Deych E, Shannon WD, Strunk RC. Daily global stress is associated with nocturnal asthma awakenings in school-age children. J Allergy Clin Immunol. 2016. PMID:27246525 
13. Horner CC, Mauger D, Strunk RC, Graber NJ, Lemanske RF Jr, Sorkness CA, Szefler SJ, Zeiger RS, Taussig LM, Bacharier LB, Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Most nocturnal asthma symptoms occur outside of exacerbations and associate with morbidity. J Allergy Clin Immunol. 2011;128(5):977-82.e1-2. doi:10.1016/j.jaci.2011.07.018  PMCID:PMC3408598  PMID:21855126 
14. Horner CC, Bacharier LB. Diagnosis and management of asthma in preschool and school-age children: focus on the 2007 NAEPP Guidelines. Curr Opin Pulm Med. 2009;15(1):52-6. doi:10.1097/MCP.0b013e32831da8ea  PMID:19077706 
15. Horner CC, Strunk RC. Age-related changes in the asthmatic phenotype in children. Curr Opin Pediatr. 2007;19(3):295-9. doi:10.1097/MOP.0b013e32809913a2  PMID:17505189 
16. Horner CC, Bacharier LB. Management approaches to intermittent wheezing in young children. Curr Opin Allergy Clin Immunol. 2007;7(2):180-4. doi:10.1097/ACI.0b013e32807fafd2  PMID:17351473 
17. Ford DA, Horner CC, Gross RW. Protein kinase C acylation by palmitoyl coenzyme A facilitates its translocation to membranes. Biochemistry. 1998;37(34):11953-61. doi:10.1021/bi980565w  PMID:9718320 
18. Ford DA, Han X, Horner CC, Gross RW. Accumulation of unsaturated acylcarnitine molecular species during acute myocardial ischemia: metabolic compartmentalization of products of fatty acyl chain elongation in the acylcarnitine pool. Biochemistry. 1996;35(24):7903-9. doi:10.1021/bi960552n  PMID:8672492