Ian T. Lackey, BS  lackey_i@kids.wustl.edu

Staff, General Medical Sciences
Pediatric Computing Facility

phone: (314) 362-9500

Clinical Interests

my bio is updating


  • BA, Brown University1993
  • MD, Brown University1997


  • Residency, Jacobi-Montefiore Medical Center, 1997 - 2001
  • Fellowship, North Shore University Hospital2001 - 2002

Licensure and Board Certification

  • A+ Certification 2000
  • MO, M.D. 2012


  • 100 Top Students Award2012

Recent Publications view all (48)

  1. Damage Control Surgery and the Management of a Cholecystocolic Fistula. Am Surg. 2017;83(4):129-130. PMID:28424117 
  2. Treatment of Leukoencephalopathy With Calcifications and Cysts With Bevacizumab. Pediatr Neurol. 2017. PMID:28424147 
  3. Synthesis, characterization, in vitro SAR and in vivo evaluation of N,N'bisnaphthylmethyl 2-alkyl substituted imidazolium salts against NSCLC. Bioorg Med Chem Lett. 2017;27(4):764-775. PMID:28126518 
  4. ddfg 2017. 
  5. Polymeric nanoparticles in development for treatment of pulmonary infectious diseases. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016;8(6):842-871. PMCID:PMC5035710  PMID:27016134 
  6. Urinary Tract Infection: Pathogenesis and Outlook. Trends Mol Med. 2016;22(11):946-957. PMCID:PMC5159206  PMID:27692880 
  7. Androgens Enhance Male Urinary Tract Infection Severity in a New Model. J Am Soc Nephrol. 2016;27(6):1625-34. PMCID:PMC4884108  PMID:26449605 
  8. Local Generation of Kynurenines Mediates Inhibition of Neutrophil Chemotaxis by Uropathogenic Escherichia coli. Infect Immun. 2016;84(4):1176-83. PMCID:PMC4807489  PMID:26857571 
  9. Klebsiella pneumoniae FimK Promotes Virulence in Murine Pneumonia. J Infect Dis. 2016;213(4):649-58. PMCID:PMC4721909  PMID:26347570 
  10. Subversion of Host Innate Immunity by Uropathogenic Escherichia coli. Pathogens. 2016;5(1). PMCID:PMC4810123  PMID:26742078 
  11. A Murine Model for Escherichia coli Urinary Tract Infection. Methods Mol Biol. 2016;1333:159-75. PMCID:PMC4624421  PMID:26468108 
  12. Imidazolium salts as small-molecule urinary bladder exfoliants in a murine model. Antimicrob Agents Chemother. 2015;59(9):5494-502. PMCID:PMC4538537  PMID:26124168 
  13. Vitamin D sufficiency and Staphylococcus aureus infection in children. Pediatr Infect Dis J. 2015;34(5):544-5. PMCID:PMC4400212  PMID:25860535 
  14. Cathelicidin augments epithelial receptivity and pathogenesis in experimental Escherichia coli cystitis. J Infect Dis. 2015;211(7):1164-73. PMCID:PMC4366604  PMID:25336727 
  15. Preparation and in vitro antimicrobial activity of silver-bearing degradable polymeric nanoparticles of polyphosphoester-block-poly(L-lactide). ACS Nano. 2015;9(2):1995-2008. PMCID:PMC4455953  PMID:25621868 
  16. Bacterial lysis liberates the neutrophil migration suppressor YbcL from the periplasm of uropathogenic Escherichia coli. Infect Immun. 2014;82(12):4921-30. PMCID:PMC4249291  PMID:25183735 
  17. Molecular Epidemiology of Recurrent Cutaneous Methicillin-Resistant Staphylococcus aureus Infections in Children. J Pediatric Infect Dis Soc. 2014;3(3):261-4. PMCID:PMC4381745  PMID:25844165 
  18. Scurvy revealed by difficulty walking: three cases in young children. J Clin Rheumatol. 2014;20(4):224-8. PMID:24847751 
  19. Vancomycin trough concentrations in overweight or obese pediatric patients. Pharmacotherapy. 2013;33(12):1273-7. PMID:23798327 
  20. A Newborn With Hydrops, Hydrocephalus, and Ophthalmologic Abnormalities. J Pediatric Infect Dis Soc. 2013;2(4):391-3. PMID:26619503 
  21. Quantitative assessment of human neutrophil migration across a cultured bladder epithelium. J Vis Exp. 2013;(81):e50919. PMCID:PMC3934319  PMID:24300797 
  22. A serologic correlate of protective immunity against community-onset Staphylococcus aureus infection. Clin Infect Dis. 2013;56(11):1554-61. PMCID:PMC3641868  PMID:23446627 
  23. YbcL of uropathogenic Escherichia coli suppresses transepithelial neutrophil migration. Infect Immun. 2012;80(12):4123-32. PMCID:PMC3497442  PMID:22966043 
  24. Oseltamivir dosing in premature infants. J Infect Dis. 2012;206(6):847-50. PMCID:PMC3572879  PMID:22807525 
  25. Induction of indoleamine 2,3-dioxygenase by uropathogenic bacteria attenuates innate responses to epithelial infection. J Infect Dis. 2012;205(12):1830-9. PMCID:PMC3415894  PMID:22474038 
  26. Synthetic polymer nanoparticles conjugated with FimH(A) from E. coli pili to emulate the bacterial mode of epithelial internalization. J Am Chem Soc. 2012;134(9):3938-41. PMCID:PMC3325780  PMID:22360307 
  27. UPEC hemolysin: more than just for making holes. Cell Host Microbe. 2012;11(1):4-5. PMCID:PMC3267088  PMID:22264508 
  28. Attenuation of human neutrophil migration and function by uropathogenic bacteria. Microbes Infect. 2011;13(6):555-65. PMCID:PMC3092803  PMID:21315174 
  29. A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. Biochemistry. 2011;50(17):3570-7. PMCID:PMC3082593  PMID:21438569 
  30. Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli. Microbes Infect. 2011;13(5):426-37. PMCID:PMC3071881  PMID:21182979 
  31. The natural history of contemporary Staphylococcus aureus nasal colonization in community children. Pediatr Infect Dis J. 2011;30(4):349-51. PMCID:PMC3077955  PMID:21412205 
  32. Shell crosslinked nanoparticles carrying silver antimicrobials as therapeutics. Chem Commun (Camb). 2010;46(1):121-3. PMCID:PMC2978063  PMID:20024313 
  33. Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli. Annu Rev Microbiol. 2010;64:203-21. PMID:20825346 
  34. OmpA of uropathogenic Escherichia coli promotes postinvasion pathogenesis of cystitis. Infect Immun. 2009;77(12):5245-51. PMCID:PMC2786482  PMID:19797074 
  35. contribution of genetically restricted, methicillin-susceptible strains to the ongoing epidemic of community-acquired Staphylococcus aureus infections. Clin Infect Dis. 2009;49(4):536-42. PMCID:PMC2965061  PMID:19589082 
  36. Virulence gene expression in human community-acquired Staphylococcus aureus infection. J Infect Dis. 2009;199(3):294-301. PMCID:PMC2843142  PMID:19115951 
  37. Components of SurA required for outer membrane biogenesis in uropathogenic Escherichia coli. PLoS One. 2008;3(10):e3359. PMCID:PMC2556385  PMID:18836534 
  38. Morphological plasticity as a bacterial survival strategy. Nat Rev Microbiol. 2008;6(2):162-8. PMID:18157153 
  39. Salmonella ovarian abscess in an adolescent. Pediatr Infect Dis J. 2007;26(6):548-9. PMID:17529879 
  40. Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A. 2006;103(52):19884-9. PMCID:PMC1750882  PMID:17172451 
  41. Maturation of intracellular Escherichia coli communities requires SurA. Infect Immun. 2006;74(8):4793-800. PMCID:PMC1539609  PMID:16861667 
  42. Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol. 2005;187(22):7680-6. PMCID:PMC1280321  PMID:16267292 
  43. Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli. Infect Immun. 2005;73(7):3999-4006. PMCID:PMC1168571  PMID:15972487 
  44. Interaction of uropathogenic Escherichia coli with host uroepithelium. Curr Opin Microbiol. 2005;8(1):54-9. PMID:15694857 
  45. Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein. J Urol. 2004;171(4):1682-5. PMCID:PMC2838480  PMID:15017266 
  46. CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli. Infect Immun. 2003;71(3):1470-80. PMCID:PMC148872  PMID:12595465 
  47. Bacterial meningitis in children. Pediatr Case Rev. 2002;2(4):195-208. PMID:12865668 
  48. test 
Last updated: 11/09/2017
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