Mark C. Johnson, M.D.

Associate Professor of Pediatrics, Cardiology
Patient Oriented Research UnitCardiology

phone: (314) 454-6095


  • M.D., Johns Hopkins University School of Medicine1982


  • Resident, , University of Colorado Health Science Center1982 - 1985
  • Fellow, Washington University School of Medicine, St. Louis Children's Hospital1990 - 1994

Licensure and Board Certification

  • MO, Missouri State Board of Registration for the Healing Arts
  • IL, Licensed Physician
  • The American Board of Pediatrics1986
  • The American Board of Pediatrics and its Subboard of Pediatric Cardiology1996


  • St. Louis Best Doctors, St. Louis Magazine2013 - Pres

Recent Publications view all (20)

Publication Co-Authors

  1. Johnson MC, Johnikin MJ, Euteneuer JC, DeBaun MR, Hildebolt C. Coronary artery dilation and left ventricular hypertrophy do not predict morbidity in children with sickle cell disease. Pediatr Blood Cancer. 2015;62(1):115-119. doi:10.1002/pbc.25239  PMID:25264310  
  2. Sanchez Mejia AA, Simpson KE, Hildebolt CF, Pahl E, Matthews KL, Rainey CA, Canter CE, Jay PY, Johnson MC. Tissue Doppler septal Tei index indicates severity of illness in pediatric patients with congestive heart failure. Pediatr Cardiol. 2014;35(3):411-8. doi:10.1007/s00246-013-0794-1  PMCID:PMC3944049  PMID:24061276  
  3. Gazit AZ, Singh GK, Johnson MC. To-and-fro murmur in the young due to major congenital cardiac defects: is cardiac auscultation obsolete? Cardiol Young. 2010;20(6):707-8. doi:10.1017/S1047951110001393  PMID:20887646  
  4. Johnson MC, Kirkham FJ Redline S, Rosen CL, Yan Y, Roberts I, Gruenwald J, Marek J, DeBaun MR. Left ventricular hypertrophy and diastolic dysfunction in children with sickle cell disease are related to asleep and waking oxygen desaturation. Blood. 2010;116(1):16-21. 
  5. Holt DB, Moller JH, Larson S, Johnson MC. Primary pulmonary vein stenosis. Amer J Card. 2007;(99):568-572. 
  6. Gazit, AZ, Singh GK, Shumway J, Johnson MC, Ludomirsky A. Fetal cardiac rhabdomyoma: A sheep or a worlf? Mat-Fet & Neo Med. 2007;20(4):343-348. 
  7. Johnson MC, Wood M, Vaughn V, Cowan L, Sharkey AM. Antibiotic and warfarin interaction in pediatric cardiology patients. Pediatric Cardiology. 2005;(26):1-5. 
  8. Nicolas RT, Hills C, Huddleston C, Moller JH, Johnson MC. Early outcome after glenn shunt and fontan palliation and the impact of operation during viral respiratory season: analysis of a 19 year multi-institutional experience. 2005;(79):613-617. 
  9. 12. Balzer DT, Johnson M, Sharkey AM, Kort H. Transcatheter occlusion of baffle leaks following atrial switch procedures for transposition of the great vessels (d-tgv). Cath Cardiovasc Interv 2004:61:259-263. Transcatheter occlusion of baffle leaks following atrial switch procedures for transposition of the great vessels (d-tgv). Cath Cardiovasc Interv. 2004;(61):259-263. 
  10. Kort HW, Balzer DT, Johnson MC. Resolution of right heart enlargement after closure of secundum atrial septal defect by transcatheter technique. J AmColl Cardiol. 2001;(38):1528-1532. 
  11. Johnson MC, Sekarski TJ, Balzer DT. Echocardiographic prediction of left-to-right shunt with atrial septal defects. J Amer Soc Echo 2000;13:1038-1042. J Amer Soc Echo. 2000;(13):1038-1042. 
  12. Benson DW, Silberbach GM, Kavanaugh-McHugh A, Cottrill C, Zhang Y, Riggs S, Smalls O, Johnson MC, Watson M, Seidman JG, Seidman CE, Graham T, Plowden J, Kugler JD. Mutations in NKX2.5, a cardiac transcription factor, affect diverse cardiac developmental pathways. J Clin Invest. 1999;(104):1567-1573. 
  13. Johnson MC, Hing A, Wood MK, Watson MS. Chromosome abnormalities in congenital heart disease. Am J Med Genet. 1997;(70):292-298. 
  14. Johnson MC, Strauss AW, Dowton SB, Spray TL, Huddleston CB, Wood MK, Slaugh RA, Watson MS. Deletion within chromosome 22 is common in patients with absent pulmonary valve syndrome. Am J Cardiol. 1995;(76):66-69. 
  15. Johnson MC, Watson MW, Strauss AW, Spray TL. Anomalous origin of the right pulmonary artery from the aorta and CATCH 22 syndrome. Ann Thorac Surg. 1995;(60):681-683. 
  16. Johnson MC, Gutierrez FR, Sekarski DR, Ong CM, Canter CE. Comparison of left ventricular mass and function in early versus late repair of coarctation of the aorta. Am J Cardiol. 1994;(73):698-701. 
  17. Johnson MC, Canter CE, Strauss AW, Spray TL . Repair of coarctation of the aorta in infancy: comparison of surgical and balloon angioplasty. American Heart Journal. 1993;(125):464-468. 
  18. Marcelino J, Carpten JD, Suwairi WM, Gutierrez OM, Schwartz S, Robbins C, Sood R, Makalowska I, Baxenanis A, Johnstone B, Laxer RM, Zemel L, Kim CA, Herd JK, Ihle JI, Williams C, Johnson M, Raman V, Alonso LG, Brunoni D, Gerstein A, Papadopoulos N,. CACP, encoding a secreted proteoglycan is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genetics. 1992;(23):319-322. 
  19. Johnson MC, Bergersen LJ, Beck A, Dick G, Cole BR. Diastolic function and tachycardia in hypertensive children. Am J Hypertens. 1992;(12):1009-1014. 
  20. Johnson MC, So S, Marsh JW, Murphy AM . QT prolongation and torsades de pointes after administration of FK506. Transplantation. 1992;(53):929-930. 
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Children's Hospital St. Louis
Children's Discovery Institute
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