Mark C. Johnson, M.D.

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Professor of Pediatrics, Cardiology

phone: (314) 454-6095

Clinical Interests

Congenital heart diseasePediatric echocardiography3D echocardiographyHeart disease with Trisomy 21 syndrome


  • BA, Summa Cum Laude, University of Rochester1978
  • MD, Johns Hopkins University School of Medicine1982


  • Resident, , University of Colorado Health Science Center1982 - 1985
  • Fellow, Washington University School of Medicine, St. Louis Children's Hospital1990 - 1994

Licensure and Board Certification

  • MO, Missouri State Board of Registration for the Healing Arts
  • IL, Licensed Physician
  • 1986 - PresThe American Board of Pediatrics
  • 1996 - PresThe American Board of Pediatrics and its Subboard of Pediatric Cardiology

Honors and Awards

  • St. Louis Best Doctors, St. Louis Magazine2013 - Pres

Recent Publications view all (24)

Publication Co-Authors

  1. 3D echocardiography provides highly accurate3D printed models in congenital heart disease Pediatric Cardiology. 2020. 
  2. Dichotomous roles of TBX3 in the establishment of atrioventricular conduction pathways in the human heart Heart Rhythm Case Reports. 2019;5:109-111. 
  3. Risk factors and prognostic significance of altered left ventricular geometry in preterm infants. J Perinatol. 2018. PMID:29410539 
  4. Normative Left Ventricular M-Mode Echocardiographic Values in Preterm Infants up to 2 kg. J Am Soc Echocardiogr. 2017. PMID:28599830 
  5. Coronary artery dilation and left ventricular hypertrophy do not predict morbidity in children with sickle cell disease. Pediatr Blood Cancer. 2015;62(1):115-119. doi:10.1002/pbc.25239  PMID:25264310 
  6. Tissue Doppler septal Tei index indicates severity of illness in pediatric patients with congestive heart failure. Pediatr Cardiol. 2014;35(3):411-8. doi:10.1007/s00246-013-0794-1  PMCID:PMC3944049  PMID:24061276 
  7. To-and-fro murmur in the young due to major congenital cardiac defects: is cardiac auscultation obsolete? Cardiol Young. 2010;20(6):707-8. doi:10.1017/S1047951110001393  PMID:20887646 
  8. Left ventricular hypertrophy and diastolic dysfunction in children with sickle cell disease are related to asleep and waking oxygen desaturation. Blood. 2010;116(1):16-21. 
  9. Primary pulmonary vein stenosis. Amer J Card. 2007;(99):568-572. 
  10. Fetal cardiac rhabdomyoma: A sheep or a worlf? Mat-Fet & Neo Med. 2007;20(4):343-348. 
  11. Antibiotic and warfarin interaction in pediatric cardiology patients. Pediatric Cardiology. 2005;(26):1-5. 
  12. Early outcome after glenn shunt and fontan palliation and the impact of operation during viral respiratory season: analysis of a 19 year multi-institutional experience. 2005;(79):613-617. 
  13. Transcatheter occlusion of baffle leaks following atrial switch procedures for transposition of the great vessels (d-tgv). Cath Cardiovasc Interv. 2004;(61):259-263. 
  14. Resolution of right heart enlargement after closure of secundum atrial septal defect by transcatheter technique. J AmColl Cardiol. 2001;(38):1528-1532. 
  15. Echocardiographic prediction of left-to-right shunt with atrial septal defects. J Amer Soc Echo 2000;13:1038-1042. J Amer Soc Echo. 2000;(13):1038-1042. 
  16. Mutations in NKX2.5, a cardiac transcription factor, affect diverse cardiac developmental pathways. J Clin Invest. 1999;(104):1567-1573. 
  17. Diastolic function and tachycardia in hypertensive children. Am J Hypertens. 1999;(12):1009-1014. 
  18. Chromosome abnormalities in congenital heart disease. Am J Med Genet. 1997;(70):292-298. 
  19. Anomalous origin of the right pulmonary artery from the aorta and CATCH 22 syndrome. Ann Thorac Surg. 1995;(60):681-683. 
  20. Deletion within chromosome 22 is common in patients with absent pulmonary valve syndrome. Am J Cardiol. 1995;(76):66-69. 
  21. Comparison of left ventricular mass and function in early versus late repair of coarctation of the aorta. Am J Cardiol. 1994;(73):698-701. 
  22. Repair of coarctation of the aorta in infancy: comparison of surgical and balloon angioplasty. American Heart Journal. 1993;(125):464-468. 
  23. CACP, encoding a secreted proteoglycan is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genetics. 1992;(23):319-322. 
  24. QT prolongation and torsades de pointes after administration of FK506. Transplantation. 1992;(53):929-930. 
Last updated: 09/16/2020
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