Department of Pediatrics

Education

• BA, University of Missouri –Kansas City School of Arts and Sciences , 2004
• MD, University of Missouri - Kansas City School of Medicine, 2005
• MSCI, Washington University in St. Louis, 2014

Training

• Pediatric Residency, St. Louis Children's Hospital, 2005 - 2008
• Neonatal-Perinatal Medicine Fellowship, Washington University School of Medicine, 2008 - 2011
• Effective Research Execution Course, Washington University in St. Louis, 2018 - 2018

Licensure and Board Certification

• 2009Board Certified in Pediatrics, American Board of Pediatrics
• 2012Board Certified in Neonatal-Perinatal Medicine, American Board of Pediatrics
• 2016MO, Registered Medical Practioner, Missouri Board of Healing Arts

Honors and Awards

• Travel Award – American Academy of Pediatrics, 2006
• Travel Award – Pediatric Academic Societies, 2010
• Washington University in St. Louis Department of Pediatrics Loan Repayment Award, 2011
• Partners in Excellence Award, Team Leader, Brigham and Women's Hospital, 2014

Recent Publications view all (25)

Publication Co-Authors

David Van Essen

Matthew Glasser

Jagruti Anadkat, M.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Cynthia M. Ortinau, M.D.

1. Bethlehem RAI, Seidlitz J, White SR, Vogel JW, Anderson KM, Adamson C, Adler S, Alexopoulos GS, Anagnostou E, Areces-Gonzalez A, Astle DE, Auyeung B, Ayub M, Bae J, Ball G, Baron-Cohen S, Beare R, Bedford SA, Benegal V, Beyer F, Blangero J, Blesa Cábez M, Boardman JP, Borzage M, Bosch-Bayard JF, Bourke N, Calhoun VD, Chakravarty MM, Chen C, Chertavian C, Chetelat G, Chong YS, Cole JH, Corvin A, Costantino M, Courchesne E, Crivello F, Cropley VL, Crosbie J, Crossley N, Delarue M, Delorme R, Desrivieres S, Devenyi GA, Di Biase MA, Dolan R, Donald KA, Donohoe G, Dunlop K, Edwards AD, Elison JT, Ellis CT, Elman JA, Eyler L, Fair DA, Feczko E, Fletcher PC, Fonagy P, Franz CE, Galan-Garcia L, Gholipour A, Giedd J, Gilmore JH, Glahn DC, Goodyer IM, Grant PE, Groenewold NA, Gunning FM, Gur RE, Gur RC, Hammill CF, Hansson O, Hedden T, Heinz A, Henson RN, Heuer K, Hoare J, Holla B, Holmes AJ, Holt R, Huang H, Im K, Ipser J, Jack CR Jr, Jackowski AP, Jia T, Johnson KA, Jones PB, Jones DT, Kahn RS, Karlsson H, Karlsson L, Kawashima R, Kelley EA, Kern S, Kim KW, Kitzbichler MG, Kremen WS, Lalonde F, Landeau B, Lee S, Lerch J, Lewis JD, Li J, Liao W, Liston C, Lombardo MV, Lv J, Lynch C, Mallard TT, Marcelis M, Markello RD, Mathias SR, Mazoyer B, McGuire P, Meaney MJ, Mechelli A, Medic N, Misic B, Morgan SE, Mothersill D, Nigg J, Ong MQW, Ortinau C, Ossenkoppele R, Ouyang M, Palaniyappan L, Paly L, Pan PM, Pantelis C, Park MM, Paus T, Pausova Z, Paz-Linares D, Pichet Binette A, Pierce K, Qian X, Qiu J, Qiu A, Raznahan A, Rittman T, Rodrigue A, Rollins CK, Romero-Garcia R, Ronan L, Rosenberg MD, Rowitch DH, Salum GA, Satterthwaite TD, Schaare HL, Schachar RJ, Schultz AP, Schumann G, Schöll M, Sharp D, Shinohara RT, Skoog I, Smyser CD, Sperling RA, Stein DJ, Stolicyn A, Suckling J, Sullivan G, Taki Y, Thyreau B, Toro R, Traut N, Tsvetanov KA, Turk-Browne NB, Tuulari JJ, Tzourio C, Vachon-Presseau É, Valdes-Sosa MJ, Valdes-Sosa PA, Valk SL, van Amelsvoort T, Vandekar SN, Vasung L, Victoria LW, Villeneuve S, Villringer A, Vértes PE, Wagstyl K, Wang YS, Warfield SK, Warrier V, Westman E, Westwater ML, Whalley HC, Witte AV, Yang N, Yeo B, Yun H, Zalesky A, Zar HJ, Zettergren A, Zhou JH, Ziauddeen H, Zugman A, Zuo XN, 3R-BRAIN., AIBL., Alzheimer’s Disease Neuroimaging Initiative., Alzheimer’s Disease Repository Without Borders Investigators., CALM Team., Cam-CAN., CCNP., COBRE., cVEDA., ENIGMA Developmental Brain Age Working Group., Developing Human Connectome Project., FinnBrain., Harvard Aging Brain Study., IMAGEN., KNE96., Mayo Clinic Study of Aging., NSPN., POND., PREVENT-AD Research Group., VETSA., Bullmore ET, Alexander-Bloch AF. Brain charts for the human lifespan. Nature. 2022. PMID:35388223 
2. Sadhwani A, Wypij D, Rofeberg V, Gholipour A, Mittleman M, Rohde J, Velasco-Annis C, Calderon J, Friedman KG, Tworetzky W, Grant PE, Soul JS, Warfield SK, Newburger JW, Ortinau CM, Rollins CK. Fetal Brain Volume Predicts Neurodevelopment in Congenital Heart Disease. Circulation. 2022. PMID:35143287 
3. Hong J, Yun HJ, Park G, Kim S, Ou Y, Vasung L, Rollins CK, Ortinau CM, Takeoka E, Akiyama S, Tarui T, Estroff JA, Grant PE, Lee JM, Im K. Optimal Method for Fetal Brain Age Prediction Using Multiplanar Slices From Structural Magnetic Resonance Imaging. Front Neurosci. 2021;15:714252. PMCID:PMC8542770  PMID:34707474 
4. Machado-Rivas F, Afacan O, Khan S, Marami B, Rollins CK, Ortinau C, Velasco-Annis C, Warfield SK, Gholipour A, Jaimes C. Tractography of the Cerebellar Peduncles in Second- and Third-Trimester Fetuses. AJNR Am J Neuroradiol. 2021;42(1):194-200. PMCID:PMC7814802  PMID:33431505 
5. Dou H, Karimi D, Rollins CK, Ortinau CM, Vasung L, Velasco-Annis C, Ouaalam A, Yang X, Ni D, Gholipour A. A Deep Attentive Convolutional Neural Network for Automatic Cortical Plate Segmentation in Fetal MRI. IEEE Trans Med Imaging. 2020;PP. PMID:33351755 
6. Hong J, Yun HJ, Park G, Kim S, Laurentys CT, Siqueira LC, Tarui T, Rollins CK, Ortinau CM, Grant PE, Lee JM, Im K. Fetal Cortical Plate Segmentation Using Fully Convolutional Networks With Multiple Plane Aggregation. Front Neurosci. 2020;14:591683. PMCID:PMC7738480  PMID:33343286 
7. Rollins CK, Ortinau CM, Stopp C, Friedman KG, Tworetzky W, Gagoski B, Velasco-Annis C, Afacan O, Vasung L, Beaute JI, Rofeberg V, Estroff JA, Grant PE, Soul JS, Yang E, Wypij D, Gholipour A, Warfield SK, Newburger JW. Regional Brain Growth Trajectories in Fetuses with Congenital Heart Disease. Ann Neurol. 2020. PMID:33084086 
8. Jaimes C, Rofeberg V, Stopp C, Ortinau CM, Gholipour A, Friedman KG, Tworetzky W, Estroff J, Newburger JW, Wypij D, Warfield SK, Yang E, Rollins CK. Association of Isolated Congenital Heart Disease with Fetal Brain Maturation. AJNR Am J Neuroradiol. 2020;41(8):1525-1531. PMID:32646947 
9. Jaimes C, Machado-Rivas F, Afacan O, Khan S, Marami B, Ortinau CM, Rollins CK, Velasco-Annis C, Warfield SK, Gholipour A. In vivo characterization of emerging white matter microstructure in the fetal brain in the third trimester. Hum Brain Mapp. 2020. PMID:32374063 
10. Yun HJ, Vasung L, Tarui T, Rollins CK, Ortinau CM, Grant PE, Im K. Temporal Patterns of Emergence and Spatial Distribution of Sulcal Pits During Fetal Life. Cereb Cortex. 2020. PMID:32219376 
11. Yun HJ, Chung AW, Vasung L, Yang E, Tarui T, Rollins CK, Ortinau CM, Grant PE, Im K. Automatic labeling of cortical sulci for the human fetal brain based on spatio-temporal information of gyrification. Neuroimage. 2019;188:473-482. PMID:30553042 
12. Khan S, Vasung L, Marami B, Rollins CK, Afacan O, Ortinau CM, Yang E, Warfield SK, Gholipour A. Fetal brain growth portrayed by a spatiotemporal diffusion tensor MRI atlas computed from in utero images. Neuroimage. 2019;185:593-608. PMCID:PMC6289660  PMID:30172006 
13. Ortinau CM, Rollins CK, Gholipour A, Yun HJ, Marshall M, Gagoski B, Afacan O, Friedman K, Tworetzky W, Warfield SK, Newburger JW, Inder TE, Grant PE, Im K. Early-Emerging Sulcal Patterns Are Atypical in Fetuses with Congenital Heart Disease. Cereb Cortex. 2018. PMCID:PMC6644862  PMID:30272144 
14. Tarui T, Madan N, Farhat N, Kitano R, Ceren Tanritanir A, Graham G, Gagoski B, Craig A, Rollins CK, Ortinau C, Iyer V, Pienaar R, Bianchi DW, Grant PE, Im K. Disorganized Patterns of Sulcal Position in Fetal Brains with Agenesis of Corpus Callosum. Cereb Cortex. 2018;28(9):3192-3203. PMCID:PMC6095213  PMID:30124828 
15. Khan S, Rollins CK, Ortinau CM, Afacan O, Warfield SK, Gholipour A. Tract-Specific Group Analysis in Fetal Cohorts Using in utero Diffusion Tensor Imaging. Med Image Comput Comput Assist Interv. 2018;11072:28-35. PMCID:PMC7456441  PMID:32869014 
16. Garcia KE, Robinson EC, Alexopoulos D, Dierker DL, Glasser MF, Coalson TS, Ortinau CM, Rueckert D, Taber LA, Van Essen DC, Rogers CE, Smyser CD, Bayly PV. Dynamic patterns of cortical expansion during folding of the preterm human brain. Proc Natl Acad Sci U S A. 2018;115(12):3156-3161. PMCID:PMC5866555  PMID:29507201 
17. Ortinau CM, Anadkat JS, Smyser CD, Eghtesady P. Intraventricular Hemorrhage in Moderate to Severe Congenital Heart Disease. Pediatr Crit Care Med. 2018;19(1):56-63. PMCID:PMC5777323  PMID:29210924 
18. Ortinau CM, Mangin-Heimos K, Moen J, Alexopoulos D, Inder TE, Gholipour A, Shimony JS, Eghtesady P, Schlaggar BL, Smyser CD. Prenatal to postnatal trajectory of brain growth in complex congenital heart disease. Neuroimage Clin. 2018;20:913-922. PMCID:PMC6178192  PMID:30308377 
19. Walsh BH, Neil J, Morey J, Yang E, Silvera MV, Inder TE, Ortinau C. The Frequency and Severity of Magnetic Resonance Imaging Abnormalities in Infants with Mild Neonatal Encephalopathy. J Pediatr. 2017;187:26-33.e1. PMCID:PMC5533615  PMID:28479101 
20. Im K, Guimaraes A, Kim Y, Cottrill E, Gagoski B, Rollins C, Ortinau C, Yang E, Grant PE. Quantitative Folding Pattern Analysis of Early Primary Sulci in Human Fetuses with Brain Abnormalities. AJNR Am J Neuroradiol. 2017;38(7):1449-1455. PMCID:PMC5509490  PMID:28522661 
21. Gholipour A, Rollins CK, Velasco-Annis C, Ouaalam A, Akhondi-Asl A, Afacan O, Ortinau CM, Clancy S, Limperopoulos C, Yang E, Estroff JA, Warfield SK. A normative spatiotemporal MRI atlas of the fetal brain for automatic segmentation and analysis of early brain growth. Sci Rep. 2017;7(1):476. PMCID:PMC5428658  PMID:28352082 
22. Estep ME, Smyser CD, Anderson PJ, Ortinau CM, Wallendorf M, Katzman CS, Doyle LW, Thompson DK, Neil JJ, Inder TE, Shimony JS. Diffusion tractography and neuromotor outcome in very preterm children with white matter abnormalities. Pediatr Res. 2014;76(1):86-92. PMCID:PMC4062577  PMID:24713814 
23. Ortinau C, Alexopoulos D, Dierker D, Van Essen D, Beca J, Inder T. Cortical folding is altered before surgery in infants with congenital heart disease. J Pediatr. 2013;163(5):1507-10. PMCID:PMC3905308  PMID:23988135 
24. Ortinau C, Inder T, Lambeth J, Wallendorf M, Finucane K, Beca J. Congenital heart disease affects cerebral size but not brain growth. Pediatr Cardiol. 2012;33(7):1138-46. PMCID:PMC3702162  PMID:22450354 
25. Ortinau, C., Beca, J., Lambeth, J., Ferdman, B., Alexopoulos, D., Shimony, J. S., Wallendorf, M., Neil, J., Inder, T. Regional alterations in cerebral growth exist preoperatively in infants with congenital heart disease. J Thorac Cardiovasc Surg. 2012;143(6):1264-70. doi:10.1016/j.jtcvs.2011.10.039  PMCID:PMC3322305  PMID:22143100