Department of Pediatrics

Education

• AB, Summa Cum Laude, University of Missouri-Columbia, 1984
• MD, Washington University School of Medicine, 1988

Training

• Residency in Pediatrics, St. Louis Children's Hospital, 1988 - 1991
• Pediatric Chief Resident, St. Louis Children's Hospital, 1991 - 1992
• Fellowship in Pediatric Emergency Medicine, Washington University in St. Louis School of Medicine, 1992 - 1994

Licensure and Board Certification

• Pediatric Advanced Life Support , 1989
• Diplomat, National Board of Medical Examiners , 1989
• Advanced Trauma Life Support , 1991
• American Board of Pediatrics (General) , 1991
• MO, Medical Licensure , 1991
• Sexual Assault Forensic Examination (S.A.F.E.)- Provider , 1992
• Advanced Cardiac Life Support , 1993
• American Board of Pediatrics, Subspecialty Pediatric Emergency Medicine , 1996
• Basic Life Support , 1996
• American Board of Pediatrics MOC Certification , 2014

Honors

• Curators' Scholar, University of Missouri-Columbia, 1981 - 1984
• Phi Beta Kappa, University of Missouri-Columbia, 1984
• Elisabeth L. Demonchaux Prize in Pediatrics, Washington University School of Medicine, 1988
• Outstanding Teacher, Subspecialty Award, St. Louis Children's Hospital, Washington University School of Medicine, Department of Emergency Medicine, 2002 - 2003
• Pediatric Clinical Educator Award, Washington University in St. Louis School of Medicine, Emergency Medicine Residents, 2008 - 2009
• Triple Crown Winner, Children's Direct St. Louis Children's Hospital, 2012
• Completion of the Academic Medical Leadership Program for Physicians and Scientists, 2017
• Triple Crown Winner, Children's Direct, 2017

Recent Publications view all (33)

1. Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, Myers SR, Nigrovic LE, Garro A, Brown KM, Quayle KS, Trainor JL, Tzimenatos L, Bennett JE, DePiero AD, Kwok MY, Perry CS 3rd, Olsen CS, Casper TC, Dean JM, Glaser NS, PECARN DKA FLUID Study Group.. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med. 2018;378(24):2275-2287. PMCID:PMC6051773  PMID:29897851 
2. Lee TS, Luhmann JD, Luhmann SJ, Quayle KS. Pediatric Lawnmower Injuries Pediatr Emerg Care. 2017;33(12):784-786. doi:10.1097/PEC.0000000000001109  PMID:28398934 
3. Garro A, Chodobski A, Szmydynger-Chodobska J, Shan R, Bialo SR, Bennett J, Quayle K, Rewers A, Schunk JE, Casper TC, Kuppermann N, Glaser N, Pediatric Emergency Care Applied Research Network (PECARN). Circulating matrix metalloproteinases in children with diabetic ketoacidosis. Pediatr Diabetes. 2017;18(2):95-102. doi:10.1111/pedi.12359  PMID:26843101 
4. Stanley RM, Johnson MD, Vance C, Bajaj L, Babcock L, Atabaki S, Thomas D, Simon HK, Cohen DM, Rubalcava D, Adelson PD, Bulloch B, Rogers AJ, Mahajan P, Baren J, Lee L, Hoyle J, Quayle K, Casper TC, Dean JM, Kuppermann N. Challenges Enrolling Children Into Traumatic Brain Injury Trials: An Observational Study Acad Emerg Med. 2017;24(1):31-39. doi:10.1111/acem.13085  PMID:27618167 
5. Tunik MG, Powell EC, Mahajan P, Schunk JE, Jacobs E, Miskin M, Zuspan SJ, Wootton-Gores S, Atabaki SM, Hoyle JD Jr, Holmes JF Jr, Dayan PS, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Clinical Presentations and Outcomes of Children With Basilar Skull Fractures After Blunt Head Trauma. Ann Emerg Med. 2016;68(4):431-440.e1. doi:10.1016/j.annemergmed.2016.04.058  PMID:27471139 
6. Borgialli DA, Mahajan P, Hoyle JD Jr, Powell EC, Nadel FM, Tunik MG, Foerster A, Dong L, Miskin M, Dayan PS, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Performance of the Pediatric Glasgow Coma Scale Score in the Evaluation of Children With Blunt Head Trauma. Acad Emerg Med. 2016;23(8):878-884. doi:10.1111/acem.13014  PMID:27197686 
7. Atabaki SM, Hoyle JD Jr, Schunk JE, Monroe DJ, Alpern ER, Quayle KS, Glass TF, Badawy MK, Miskin M, Schalick WO, Dayan PS, Holmes JF, Kuppermann N. Comparison of Prediction Rules and Clinician Suspicion for Identifying Children With Clinically Important Brain Injuries After Blunt Head Trauma. Acad Emerg Med. 2016;23(5):566-575. doi:10.1111/acem.12923  PMID:26825755 
8. Natale JE, Joseph JG, Rogers AJ, Tunik M, Monroe D, Kerrey B, Bonsu BK, Cook LJ, Page K, Adelgais K, Quayle K, Kuppermann N, Holmes JF. Relationship of Physician-identified Patient Race and Ethnicity to Use of Computed Tomography in Pediatric Blunt Torso Trauma. Acad Emerg Med. 2016;23(5):584-590. doi:10.1111/acem.12943  PMID:26914184 
9. Lichenstein R, Monroe D, Quayle KS, Miskin M, Cooper A, Gerardi MJ, Callahan JM, Dayan PS, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Television-Related Head Injuries in Children: A Secondary Analysis of a Large Cohort Study of Head-Injured Children in the Pediatric Emergency Care Applied Research Network. Pediatr Emerg Care. 2015. doi:10.1097/PEC.0000000000000605  PMID:26555312 
10. Ellison AM, Quayle KS, Bonsu B, Garcia M, Blumberg S, Rogers A, Wootton-Gorges SL, Kerrey BT, Cook LJ, Cooper A, Kuppermann N, Holmes JF, Pediatric Emergency Care Applied Research Network (PECARN), Pediatric Emergency Care Applied Research Network PECARN. Use of Oral Contrast for Abdominal Computed Tomography in Children With Blunt Torso Trauma. Ann Emerg Med. 2015;66(2):107-114.e4. doi:10.1016/j.annemergmed.2015.01.014  PMID:25794610 
11. Powell EC, Atabaki SM, Wootton-Gorges S, Wisner D, Mahajan P, Glass T, Miskin M, Stanley RM, Jacobs E, Dayan PS, Holmes JF, Kuppermann N. Isolated Linear Skull Fractures in Children With Blunt Head Trauma Pediatrics. 2015;135(4):e851-e857. 
12. Kwok MY, Yen K, Atabaki S, Adelgais K, Garcia M, Quayle K, Kooistra J, Bonsu BK, Page K, Borgialli D, Kuppermann N, Holmes JF. Sensitivity of plain pelvis radiography in children with blunt torso trauma. Ann Emerg Med. 2015;65(1):63-71.e1. doi:10.1016/j.annemergmed.2014.06.017  PMID:25086474 
13. Stanley RM, Hoyle JD Jr, Dayan PS, Atabaki S, Lee L, Lillis K, Gorelick MH, Holubkov R, Miskin M, Holmes JF, Dean JM, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Emergency department practice variation in computed tomography use for children with minor blunt head trauma. J Pediatr. 2014;165(6):1201-1206.e2. doi:10.1016/j.jpeds.2014.08.008  PMID:25294604 
14. Adelgais KM, Kuppermann N, Kooistra J, Garcia M, Monroe DJ, Mahajan P, Menaker J, Ehrlich P, Atabaki S, Page K, Kwok M, Holmes JF, Intra-Abdominal Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Accuracy of the abdominal examination for identifying children with blunt intra-abdominal injuries. J Pediatr. 2014;165(6):1230-1235.e5. doi:10.1016/j.jpeds.2014.08.014  PMID:25266346 
15. Quayle KS, Powell EC, Mahajan P, Hoyle JD Jr, Nadel FM, Badawy MK, Schunk JE, Stanley RM, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N. Epidemiology of blunt head trauma in children in U.S. emergency departments. N Engl J Med. 2014;371(20):1945-1947. doi:10.1056/NEJMc1407902  PMID:25390756 
16. Lee LK, Monroe D, Bachman MC, Glass TF, Mahajan PV, Cooper A, Stanley RM, Miskin M, Dayan PS, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of Pediatric Emergency Care Applied Research Network (PECARN). Isolated loss of consciousness in children with minor blunt head trauma. JAMA Pediatr. 2014;168(9):837-843. doi:10.1001/jamapediatrics.2014.361  PMID:25003654 
17. Dayan PS, Holmes JF, Schutzman S, Schunk J, Lichenstein R, Foerster LA, Hoyle J Jr, Atabaki S, Miskin M, Wisner D, Zuspan S, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Risk of traumatic brain injuries in children younger than 24 months with isolated scalp hematomas. Ann Emerg Med. 2014;64(2):153-162. doi:10.1016/j.annemergmed.2014.02.003  PMID:24635991 
18. Dayan PS, Holmes JF, Atabaki S, Hoyle J Jr, Tunik MG, Lichenstein R, Alpern E, Miskin M, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Association of traumatic brain injuries with vomiting in children with blunt head trauma. Ann Emerg Med. 2014;63(6):657-665. doi:10.1016/j.annemergmed.2014.01.009  PMID:24559605 
19. Kerrey BT, Rogers AJ, Lee LK, Adelgais K, Tunik M, Blumberg SM, Quayle KS, Sokolove PE, Wisner DH, Miskin ML, Kuppermann N, Holmes JF, Pediatric Emergency Care Applied Research Network. A multicenter study of the risk of intra-abdominal injury in children after normal abdominal computed tomography scan results in the emergency department. Ann Emerg Med. 2013;62(4):319-326. doi:10.1016/j.annemergmed.2013.04.006  PMID:23622949 
20. Glaser NS, Ghetti S, Casper TC, Dean JM, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group. Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial. Pediatr Diabetes. 2013;14(6):435-446. doi:10.1111/pedi.12027  PMCID:PMC3687019  PMID:23490311 
21. Holmes JF, Lillis K, Monroe D, Borgialli D, Kerrey BT, Mahajan P, Adelgais K, Ellison AM, Yen K, Atabaki S, Menaker J, Bonsu B, Quayle KS, Garcia M, Rogers A, Blumberg S, Lee L, Tunik M, Kooistra J, Kwok M, Cook LJ, Dean JM, Sokolove PE, Wisner DH, Ehrlich P, Cooper A, Dayan PS, Wootton-Gorges S, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Identifying children at very low risk of clinically important blunt abdominal injuries. Ann Emerg Med. 2013;62(2):107-116.e2. doi:10.1016/j.annemergmed.2012.11.009  PMID:23375510 
22. Rogers AJ, Maher CO, Schunk JE, Quayle K, Jacobs E, Lichenstein R, Powell E, Miskin M, Dayan P, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network. Incidental findings in children with blunt head trauma evaluated with cranial CT scans. Pediatrics. 2013;132(2):e356-363. doi:10.1542/peds.2013-0299  PMID:23878053 
23. Linscott LL, Kessler MM, Kitchin DR, Quayle KS, Hildebolt CF, McKinstry RC, Don S. CT for pediatric, acute, minor head trauma: clinician conformity to published guidelines. Am J Neuroradiol. 2013;34(6):1252-1256. doi:10.3174/ajnr.A3366  PMID:23221949 
24. Nigrovic LE, Lillis K, Atabaki SM, Dayan PS, Hoyle J, Tunik MG, Jacobs ES, Monroe D, Wootton-Gorges SW, Miskin M, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of the Pediatric Emergency Care Applied Research Network (PECARN). The prevalence of traumatic brain injuries after minor blunt head trauma in children with ventricular shunts. Ann Emerg Med. 2013;61(4):389-393. doi:10.1016/j.annemergmed.2012.08.030  PMID:23122954 
25. Lichenstein R, Glass TF, Quayle KS, Wootton-Gorges SL, Wisner DH, Miskin M, Muizelaar JP, Badawy M, Atabaki S, Holmes JF, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Presentations and outcomes of children with intraventricular hemorrhages after blunt head trauma. Arch Pediatr Adolesc Med. 2012;166(8):725-731. doi:10.1001/archpediatrics.2011.1919  PMID:22473883 
26. Nigrovic LE, Lee LK, Hoyle J, Stanley RM, Gorelick MH, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of Pediatric Emergency Care Applied Research Network (PECARN). Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms. Arch Pediatr Adolesc Med. 2012;166(4):356-361. doi:10.1001/archpediatrics.2011.1156  PMID:22147762 
27. Holmes JF, Borgialli DA, Nadel FM, Quayle KS, Schambam N, Cooper A, Schunk JE, Miskin ML, Atabaki SM, Hoyle JD, Dayan PS, Kuppermann N, TBI Study Group for the Pediatric Emergency Care Applied Research Network. Do children with blunt head trauma and normal cranial computed tomography scan results require hospitalization for neurologic observation? Ann Emerg Med. 2011;58(4):315-322. doi:10.1016/j.annemergmed.2011.03.060  PMID:21683474 
28. Kuppermann N, Holmes JF, Dayan PS, Hoyle JD Jr, Atabaki SM, Holubkov R, Nadel FM, Monroe D, Stanley RM, Borgialli DA, Badawy MK, Schunk JE, Quayle KS, Mahajan P, Lichenstein R, Lillis KA, Tunik MG, Jacobs ES, Callahan JM, Gorelick MH, Glass TF, Lee LK, Bachman MC, Cooper A, Powell EC, Gerardi MJ, Melville KA, Muizelaar JP, Wisner DH, Zuspan SJ, Dean JM, Wootton-Gorges SL, Pediatric Emergency Care Applied Research Network (PECARN). Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. Lancet. 2009;374(9696):1160-1170. doi:10.1016/S0140-6736(09)61558-0  PMID:19758692 
29. Williams KG, Schootman M, Quayle KS, Struthers J, Jaffe DM. Geographic variation of pediatric burn injuries in a metropolitan area. Acad Emerg Med. 2003;10(7):743-752. PMID:12837649 
30. Marcin JP, Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N, American Academy of Pediatrics, The Pediatric Emergency Medicine Collaborative Research Commitee. Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edema. J Pediatr. 2002;141(6):793-797. PMID:12461495 
31. Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N, Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. N Engl J Med. 2001;344(4):264-269. doi:10.1056/NEJM200101253440404  PMID:11172153 
32. Quayle KS, Wick NA, Gnauck KA, Schootman M, Jaffe DM. Description of Missouri children who suffer burn injuries. Inj Prev. 2000;6(4):255-258. PMCID:PMC1730668  PMID:11144622 
33. Quayle KS, Jaffe DM, Kuppermann N, Kaufman BA, Lee BC, Park TS, McAlister WH. Diagnostic testing for acute head injury in children: when are head computed tomography and skull radiographs indicated? Pediatrics. 1997;99(5):E11. PMID:9113968