Department of Pediatrics

Education

• AB, Summa Cum Laude, University of Missouri-Columbia, 1984
• MD, Washington University School of Medicine, 1988

Training

• Residency in Pediatrics, St. Louis Children's Hospital, 1988 - 1991
• Pediatric Chief Resident, St. Louis Children's Hospital, 1991 - 1992
• Fellowship in Pediatric Emergency Medicine, Washington University in St. Louis School of Medicine, 1992 - 1994

Licensure and Board Certification

• 1989 - PresPediatric Advanced Life Support
• 1989Diplomat, National Board of Medical Examiners
• 1991 - PresAdvanced Trauma Life Support
• 1991 - PresAmerican Board of Pediatrics (General)
• 1991 - PresMO, Medical Licensure
• 1992Sexual Assault Forensic Examination (S.A.F.E.)- Provider
• 1993Advanced Cardiac Life Support
• 1996 - PresAmerican Board of Pediatrics, Subspecialty Pediatric Emergency Medicine
• 1996Basic Life Support
• 2014 - PresAmerican Board of Pediatrics MOC Certification

Honors and Awards

• Curators' Scholar, University of Missouri-Columbia, 1981 - 1984
• Phi Beta Kappa, University of Missouri-Columbia, 1984
• Elisabeth L. Demonchaux Prize in Pediatrics, Washington University School of Medicine, 1988
• Outstanding Teacher, Subspecialty Award, St. Louis Children's Hospital, Washington University School of Medicine, Department of Emergency Medicine, 2002 - 2003
• Pediatric Clinical Educator Award, Washington University in St. Louis School of Medicine, Emergency Medicine Residents, 2008 - 2009
• Triple Crown Winner, Children's Direct St. Louis Children's Hospital, 2012
• Completion of the Academic Medical Leadership Program for Physicians and Scientists, 2017
• Triple Crown Winner, Children's Direct, 2017
• 2019 Alumni Faculty Achievement Award, Washington University Medical Center Alumni Association, 2019
• Best PEM MD Award, Emergency Medicine Residents, 2019
• WUSM Alumni Association Distinguished Alumni Scholarship Honoree, 2020

Recent Publications view all (43)

Publication Co-Authors

Charles Samson, M.D.

Scott Saunders, M.D., Ph.D.

Fahd Ahmad, M.D., M.S.C.I.

Celeste C. Brancato, M.D.

Nikoleta S. Kolovos, M.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Kimberly S. Quayle, M.D.

1. Kuppermann N, DePiero A, Brown K, Schunk J, McManemy J, Rewers A, Stoner M, Tzimenatos L, Garro A, Myers SR, Quayle KS, Trainor JL, Kwok MY, Nigrovic L, Olsen C, Casey C, Ghetti S. Hypertension During Diabetic Ketoacidosis in Children Journal of Pediatrics. 2021;223:156-163.e5. doi:10.1016/j.jpeds.2020.04.066  PMCID:PMC7414786  PMID:32387716 
2. Bram S, Quayle KS, Schmidt T, Lloyd J, Ellsworth S, Srinivasin M. Use of a sterile collection process to reduce contaminated peripheral blood cultures HOSPPEDS. 2021. 
3. Glaser NS, Stoner M, Risgarro A, Myers S, Rewers A, Brown K, Trainor J, Quayle K, McManemy J, Depiero A, Nigrovic L, Stzmenatos L, Shunk J, Olsen C, Casper, Kuppermann N, JSB. Serum Sodium Concentration and Mental Status in Diabetic Ketoacidosis Pediatrics. 2021. 
4. Rewers A, Glaser N, Olsen C, Casper C, Ghetti S, Myers S, Trainor J, Nigrovic L, Garro A, Tzimenatos L, Quayle KS, Kwok M, Stoner M, Schunk J, McManemy J, Brown K, Pilkey D, Fanflik P, Kuhn R, Kuppermann N. Emerging Therapies: Drugs and Regimens - Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children with Diabetic Ketoacidosis Diabetes Care. 2020. doi:DC20-3113.R1  
5. Sage R. Myers, MD, MSCE; Nicole S. Glaser, MD; Jennifer L. Trainor, MD; Lise E. Nigrovic,MD, MPH; Aris Garro,MD, MPH; Leah Tzimenatos, MD; Kimberly S. Quayle, MD; Maria Y. Kwok, MD, MPH; Arleta Rewers, MD, PhD; Michael J. Stoner, MD; Jeff E. Schunk, MD; Julie K. McManemy, MD, MPH; Kathleen M. Brown, MD;Andrew D. DePiero, MD; Cody S. Olsen, MS; T. Charles Casper, PhD; Simona Ghetti, PhD; Nathan Kuppermann, MD, MPH;for the Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group. Frequency and Risk Factors of Acute Kidney Injury During Diabetic Ketoacidosisin Children and Association With Neurocognitive Outcomes JAMA Network Open 2020;3(12)e2025481. 2020. doi:10:1001/jamanetworkopen 2020.25481  PMCID:PMC7718599  PMID:33275152 
6. Kupperman N, Ghetti S, Glaser N, Olsen C, Casper C, Myers S, Tzimenatos L, Quayle KS, Kwok M, Rewers A, Stoner M, Depiero A, Trainor J, Nigrovic L, Risgarro A, Schunk J, McManemy J, Brown K, Pilkey D, Kinsman S, Dean M, Zuspan S, Fanflik P, Lerner B . Pathophysiology/Complications - Cognitive Function following Diabetic Ketoacidosis in Children with New Onset or Previously Diagnosed Type 1 Diabetes Care. 2020;43(11):2768-2775. doi:10.2337/DC20-0187  PMID:32962981 
7. Curfman A, Groenendyk J, Markham C, Quayle KS, Turmelle M, Tieken B, Brancato C, Saunders S. Implementation of Telemedicine in Pediatric and Neonatal Transport AIRMEDJ-D-19-00069R1. 2020. doi:10.1016/j.amj.2020.04.008  PMID:32690303 
8. Chamberlain JM, Kapur J, Shinnar S, Elm J, Holsti M, Babcock L, Rogers A, Barsan W, Cloyd J, Lowenstein D, Bleck TP, Conwit R, Meinzer C, Cock H, Fountain NB, Underwood E, Connor JT, Silbergleit R, Neurological Emergencies Treatment Trials., Pediatric Emergency Care Applied Research Network investigators.. Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial. Lancet. 2020;395(10231):1217-1224. PMID:32203691 
9. Kapur J, Elm J, Chamberlain JM, Barsan W, Cloyd J, Lowenstein D, Shinnar S, Conwit R, Meinzer C, Cock H, Fountain N, Connor JT, Silbergleit R, NETT and PECARN Investigators.. Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus. N Engl J Med. 2019;381(22):2103-2113. PMCID:PMC7098487  PMID:31774955 
10. Puffenbarger MS, Ahmad FA, Argent M, Gu H, Samson C, Quayle KS, Saito JM. Reduction of Computed Tomography Use for Pediatric Closed Head Injury Evaluation at a Nonpediatric Community Emergency Department. Acad Emerg Med. 2019;26(7):784-795. PMID:30428150 
11. Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, Myers SR, Nigrovic LE, Garro A, Brown KM, Quayle KS, Trainor JL, Tzimenatos L, Bennett JE, DePiero AD, Kwok MY, Perry CS 3rd, Olsen CS, Casper TC, Dean JM, Glaser NS, PECARN DKA FLUID Study Group.. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med. 2018;378(24):2275-2287. PMCID:PMC6051773  PMID:29897851 
12. Lee TS, Luhmann JD, Luhmann SJ, Quayle KS. Pediatric Lawnmower Injuries Pediatr Emerg Care. 2017;33(12):784-786. doi:10.1097/PEC.0000000000001109  PMID:28398934 
13. Garro A, Chodobski A, Szmydynger-Chodobska J, Shan R, Bialo SR, Bennett J, Quayle K, Rewers A, Schunk JE, Casper TC, Kuppermann N, Glaser N, Pediatric Emergency Care Applied Research Network (PECARN). Circulating matrix metalloproteinases in children with diabetic ketoacidosis. Pediatr Diabetes. 2017;18(2):95-102. doi:10.1111/pedi.12359  PMID:26843101 
14. Stanley RM, Johnson MD, Vance C, Bajaj L, Babcock L, Atabaki S, Thomas D, Simon HK, Cohen DM, Rubalcava D, Adelson PD, Bulloch B, Rogers AJ, Mahajan P, Baren J, Lee L, Hoyle J, Quayle K, Casper TC, Dean JM, Kuppermann N. Challenges Enrolling Children Into Traumatic Brain Injury Trials: An Observational Study Acad Emerg Med. 2017;24(1):31-39. doi:10.1111/acem.13085  PMID:27618167 
15. Tunik MG, Powell EC, Mahajan P, Schunk JE, Jacobs E, Miskin M, Zuspan SJ, Wootton-Gores S, Atabaki SM, Hoyle JD Jr, Holmes JF Jr, Dayan PS, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Clinical Presentations and Outcomes of Children With Basilar Skull Fractures After Blunt Head Trauma. Ann Emerg Med. 2016;68(4):431-440.e1. doi:10.1016/j.annemergmed.2016.04.058  PMID:27471139 
16. Borgialli DA, Mahajan P, Hoyle JD Jr, Powell EC, Nadel FM, Tunik MG, Foerster A, Dong L, Miskin M, Dayan PS, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Performance of the Pediatric Glasgow Coma Scale Score in the Evaluation of Children With Blunt Head Trauma. Acad Emerg Med. 2016;23(8):878-884. doi:10.1111/acem.13014  PMID:27197686 
17. Atabaki SM, Hoyle JD Jr, Schunk JE, Monroe DJ, Alpern ER, Quayle KS, Glass TF, Badawy MK, Miskin M, Schalick WO, Dayan PS, Holmes JF, Kuppermann N. Comparison of Prediction Rules and Clinician Suspicion for Identifying Children With Clinically Important Brain Injuries After Blunt Head Trauma. Acad Emerg Med. 2016;23(5):566-575. doi:10.1111/acem.12923  PMID:26825755 
18. Natale JE, Joseph JG, Rogers AJ, Tunik M, Monroe D, Kerrey B, Bonsu BK, Cook LJ, Page K, Adelgais K, Quayle K, Kuppermann N, Holmes JF. Relationship of Physician-identified Patient Race and Ethnicity to Use of Computed Tomography in Pediatric Blunt Torso Trauma. Acad Emerg Med. 2016;23(5):584-590. doi:10.1111/acem.12943  PMID:26914184 
19. Lichenstein R, Monroe D, Quayle KS, Miskin M, Cooper A, Gerardi MJ, Callahan JM, Dayan PS, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Television-Related Head Injuries in Children: A Secondary Analysis of a Large Cohort Study of Head-Injured Children in the Pediatric Emergency Care Applied Research Network. Pediatr Emerg Care. 2015. doi:10.1097/PEC.0000000000000605  PMID:26555312 
20. Ellison AM, Quayle KS, Bonsu B, Garcia M, Blumberg S, Rogers A, Wootton-Gorges SL, Kerrey BT, Cook LJ, Cooper A, Kuppermann N, Holmes JF, Pediatric Emergency Care Applied Research Network (PECARN), Pediatric Emergency Care Applied Research Network PECARN. Use of Oral Contrast for Abdominal Computed Tomography in Children With Blunt Torso Trauma. Ann Emerg Med. 2015;66(2):107-114.e4. doi:10.1016/j.annemergmed.2015.01.014  PMID:25794610 
21. Powell EC, Atabaki SM, Wootton-Gorges S, Wisner D, Mahajan P, Glass T, Miskin M, Stanley RM, Jacobs E, Dayan PS, Holmes JF, Kuppermann N. Isolated Linear Skull Fractures in Children With Blunt Head Trauma Pediatrics. 2015;135(4):e851-e857. 
22. Kwok MY, Yen K, Atabaki S, Adelgais K, Garcia M, Quayle K, Kooistra J, Bonsu BK, Page K, Borgialli D, Kuppermann N, Holmes JF. Sensitivity of plain pelvis radiography in children with blunt torso trauma. Ann Emerg Med. 2015;65(1):63-71.e1. doi:10.1016/j.annemergmed.2014.06.017  PMID:25086474 
23. Stanley RM, Hoyle JD Jr, Dayan PS, Atabaki S, Lee L, Lillis K, Gorelick MH, Holubkov R, Miskin M, Holmes JF, Dean JM, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Emergency department practice variation in computed tomography use for children with minor blunt head trauma. J Pediatr. 2014;165(6):1201-1206.e2. doi:10.1016/j.jpeds.2014.08.008  PMID:25294604 
24. Adelgais KM, Kuppermann N, Kooistra J, Garcia M, Monroe DJ, Mahajan P, Menaker J, Ehrlich P, Atabaki S, Page K, Kwok M, Holmes JF, Intra-Abdominal Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Accuracy of the abdominal examination for identifying children with blunt intra-abdominal injuries. J Pediatr. 2014;165(6):1230-1235.e5. doi:10.1016/j.jpeds.2014.08.014  PMID:25266346 
25. Quayle KS, Powell EC, Mahajan P, Hoyle JD Jr, Nadel FM, Badawy MK, Schunk JE, Stanley RM, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N. Epidemiology of blunt head trauma in children in U.S. emergency departments. N Engl J Med. 2014;371(20):1945-1947. doi:10.1056/NEJMc1407902  PMID:25390756 
26. Lee LK, Monroe D, Bachman MC, Glass TF, Mahajan PV, Cooper A, Stanley RM, Miskin M, Dayan PS, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of Pediatric Emergency Care Applied Research Network (PECARN). Isolated loss of consciousness in children with minor blunt head trauma. JAMA Pediatr. 2014;168(9):837-843. doi:10.1001/jamapediatrics.2014.361  PMID:25003654 
27. Dayan PS, Holmes JF, Schutzman S, Schunk J, Lichenstein R, Foerster LA, Hoyle J Jr, Atabaki S, Miskin M, Wisner D, Zuspan S, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Risk of traumatic brain injuries in children younger than 24 months with isolated scalp hematomas. Ann Emerg Med. 2014;64(2):153-162. doi:10.1016/j.annemergmed.2014.02.003  PMID:24635991 
28. Dayan PS, Holmes JF, Atabaki S, Hoyle J Jr, Tunik MG, Lichenstein R, Alpern E, Miskin M, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Association of traumatic brain injuries with vomiting in children with blunt head trauma. Ann Emerg Med. 2014;63(6):657-665. doi:10.1016/j.annemergmed.2014.01.009  PMID:24559605 
29. Kerrey BT, Rogers AJ, Lee LK, Adelgais K, Tunik M, Blumberg SM, Quayle KS, Sokolove PE, Wisner DH, Miskin ML, Kuppermann N, Holmes JF, Pediatric Emergency Care Applied Research Network. A multicenter study of the risk of intra-abdominal injury in children after normal abdominal computed tomography scan results in the emergency department. Ann Emerg Med. 2013;62(4):319-326. doi:10.1016/j.annemergmed.2013.04.006  PMID:23622949 
30. Glaser NS, Ghetti S, Casper TC, Dean JM, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group. Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial. Pediatr Diabetes. 2013;14(6):435-446. doi:10.1111/pedi.12027  PMCID:PMC3687019  PMID:23490311 
31. Holmes JF, Lillis K, Monroe D, Borgialli D, Kerrey BT, Mahajan P, Adelgais K, Ellison AM, Yen K, Atabaki S, Menaker J, Bonsu B, Quayle KS, Garcia M, Rogers A, Blumberg S, Lee L, Tunik M, Kooistra J, Kwok M, Cook LJ, Dean JM, Sokolove PE, Wisner DH, Ehrlich P, Cooper A, Dayan PS, Wootton-Gorges S, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN). Identifying children at very low risk of clinically important blunt abdominal injuries. Ann Emerg Med. 2013;62(2):107-116.e2. doi:10.1016/j.annemergmed.2012.11.009  PMID:23375510 
32. Rogers AJ, Maher CO, Schunk JE, Quayle K, Jacobs E, Lichenstein R, Powell E, Miskin M, Dayan P, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network. Incidental findings in children with blunt head trauma evaluated with cranial CT scans. Pediatrics. 2013;132(2):e356-363. doi:10.1542/peds.2013-0299  PMID:23878053 
33. Linscott LL, Kessler MM, Kitchin DR, Quayle KS, Hildebolt CF, McKinstry RC, Don S. CT for pediatric, acute, minor head trauma: clinician conformity to published guidelines. Am J Neuroradiol. 2013;34(6):1252-1256. doi:10.3174/ajnr.A3366  PMID:23221949 
34. Nigrovic LE, Lillis K, Atabaki SM, Dayan PS, Hoyle J, Tunik MG, Jacobs ES, Monroe D, Wootton-Gorges SW, Miskin M, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of the Pediatric Emergency Care Applied Research Network (PECARN). The prevalence of traumatic brain injuries after minor blunt head trauma in children with ventricular shunts. Ann Emerg Med. 2013;61(4):389-393. doi:10.1016/j.annemergmed.2012.08.030  PMID:23122954 
35. Lichenstein R, Glass TF, Quayle KS, Wootton-Gorges SL, Wisner DH, Miskin M, Muizelaar JP, Badawy M, Atabaki S, Holmes JF, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Presentations and outcomes of children with intraventricular hemorrhages after blunt head trauma. Arch Pediatr Adolesc Med. 2012;166(8):725-731. doi:10.1001/archpediatrics.2011.1919  PMID:22473883 
36. Nigrovic LE, Lee LK, Hoyle J, Stanley RM, Gorelick MH, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of Pediatric Emergency Care Applied Research Network (PECARN). Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms. Arch Pediatr Adolesc Med. 2012;166(4):356-361. doi:10.1001/archpediatrics.2011.1156  PMID:22147762 
37. Holmes JF, Borgialli DA, Nadel FM, Quayle KS, Schambam N, Cooper A, Schunk JE, Miskin ML, Atabaki SM, Hoyle JD, Dayan PS, Kuppermann N, TBI Study Group for the Pediatric Emergency Care Applied Research Network. Do children with blunt head trauma and normal cranial computed tomography scan results require hospitalization for neurologic observation? Ann Emerg Med. 2011;58(4):315-322. doi:10.1016/j.annemergmed.2011.03.060  PMID:21683474 
38. Kuppermann N, Holmes JF, Dayan PS, Hoyle JD Jr, Atabaki SM, Holubkov R, Nadel FM, Monroe D, Stanley RM, Borgialli DA, Badawy MK, Schunk JE, Quayle KS, Mahajan P, Lichenstein R, Lillis KA, Tunik MG, Jacobs ES, Callahan JM, Gorelick MH, Glass TF, Lee LK, Bachman MC, Cooper A, Powell EC, Gerardi MJ, Melville KA, Muizelaar JP, Wisner DH, Zuspan SJ, Dean JM, Wootton-Gorges SL, Pediatric Emergency Care Applied Research Network (PECARN). Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. Lancet. 2009;374(9696):1160-1170. doi:10.1016/S0140-6736(09)61558-0  PMID:19758692 
39. Williams KG, Schootman M, Quayle KS, Struthers J, Jaffe DM. Geographic variation of pediatric burn injuries in a metropolitan area. Acad Emerg Med. 2003;10(7):743-752. PMID:12837649 
40. Marcin JP, Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N, American Academy of Pediatrics, The Pediatric Emergency Medicine Collaborative Research Commitee. Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edema. J Pediatr. 2002;141(6):793-797. PMID:12461495 
41. Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N, Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. N Engl J Med. 2001;344(4):264-269. doi:10.1056/NEJM200101253440404  PMID:11172153 
42. Quayle KS, Wick NA, Gnauck KA, Schootman M, Jaffe DM. Description of Missouri children who suffer burn injuries. Inj Prev. 2000;6(4):255-258. PMCID:PMC1730668  PMID:11144622 
43. Quayle KS, Jaffe DM, Kuppermann N, Kaufman BA, Lee BC, Park TS, McAlister WH. Diagnostic testing for acute head injury in children: when are head computed tomography and skull radiographs indicated? Pediatrics. 1997;99(5):E11. PMID:9113968