Clinical Interests

My clinical areas of interest include pediatric inflammatory bowel disease and general pediatric gastrointestinal illness.

Education

  • B.S., Highest Distinction and Highest Honors, University of North Carolina at Chapel Hill1998
  • M.D., Thesis Honors, University of Washington2003

Training

  • Pediatric Residency, Univeristy of North Carolina at Chapel Hill/NC Children's Hospital2003 - 2006
  • Pediatric Gastroenterology Fellowship, Cincinnati Children's Hospital Medical Center2006 - 2009
  • Advanced Improvement Methods Workshop, Cincinnati Children's Hospital Medical Center2014 - 2015
  • Pediatric Leadership Development Program, Washington University School of Medicine2016 - 2016

Licensure and Board Certification

  • NC, NC Training License2003
  • OH, Ohio Training Certificate2006
  • American Board of Pediatrics; General Pediatrics2006
  • OH, Ohio Medical License2009
  • American Board of Pediatrics; Pediatric Gastroenterology2009
  • MO, Missouri Medical License2011
  • AR, Arkansas Medical License2016

Honors

  • David L Stern Award; Department of Chemistry; University of North Carolina at Chapel Hill1997
  • Phi Beta Kappa; University of North Carolina at Chapel Hill1997
  • Highest Distinction Graduate; University of North Carolina at Chapel Hill1998
  • Highest Honor's Thesis in Chemistry; University of North Carolina at Chapel Hill1998
  • Venable Medal; Department of Chemistry; University of North Carolina at Chapel Hill1998
  • Medical Thesis Honors; University of Washington School of Medicine2002
  • Fellowship to Facutly Transition Award; Foundation of the American Gastroenterological Association2009
  • Pediatric Loan Repayment Award; National Institutes of Health2009
  • Procter Scholar Award; Cincinnati Children's Hospital Medical Center2009
  • Poster of Distinction, Digestive Disease Week2011

Recent Publications view all (14)


  1. Samson CM, Mager D, Frazee S, Yu F. Remission in Pediatric Inflammatory Bowel Disease Correlates with Prescription Refill Adherence Rates. J Pediatr Gastroenterol Nutr. 2016. PMID:27299424  
  2. Samson CM, Morgan P, Williams E, Beck L, Addie-Carson R, McIntire S, Booth A, Mendez E, Luzader C, Tomer G, Saeed S, Donovan E, Bucuvalas J, Denson LA. Improved outcomes with quality improvement interventions in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2012;55(6):679-88. doi:10.1097/MPG.0b013e318262de16  PMID:22699837  
  3. Otley A, LeLeiko N, Langton C, Lerer T, Mack D, Evans J, Pfefferkorn M, Carvalho R, Rosh J, Griffiths A, Oliva-Hemker M, Kay M, Bousvaros A, Stephens M, Samson C, Grossman A, Keljo D, Markowitz J, Hyams J, Pediatric IBD Collaborative Research Group. Budesonide use in pediatric Crohn disease. J Pediatr Gastroenterol Nutr. 2012;55(2):200-4. doi:10.1097/MPG.0b013e31824a09c2  PMID:22258289  
  4. Crandall WV, Margolis PA, Kappelman MD, King EC, Pratt JM, Boyle BM, Duffy LF, Grunow JE, Kim SC, Leibowitz I, Schoen BT, Colletti RB, ImproveCareNow Collaborative. Improved outcomes in a quality improvement collaborative for pediatric inflammatory bowel disease. Pediatrics. 2012;129(4):e1030-41. doi:10.1542/peds.2011-1700  PMCID:PMC3313634  PMID:22412030  
  5. Samson CM, Jurickova I, Molden E, Schreiner W, Colliver J, Bonkowski E, Han X, Trapnell BC, Denson LA. Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice. Inflamm Bowel Dis. 2011;17(12):2443-55. doi:10.1002/ibd.21672  PMCID:PMC3111853  PMID:21381154  
  6. Hyams JS, Lerer T, Mack D, Bousvaros A, Griffiths A, Rosh J, Otley A, Evans J, Stephens M, Kay M, Keljo D, Pfefferkorn M, Saeed S, Crandall W, Michail S, Kappelman MD, Grossman A, Samson C, Sudel B, Oliva-Hemker M, Leleiko N, Markowitz J, Pediatric Infl ammatory Bowel Disease Collaborative Research Group Registry. Outcome following thiopurine use in children with ulcerative colitis: a prospective multicenter registry study. Am J Gastroenterol. 2011;106(5):981-7. doi:10.1038/ajg.2010.493  PMID:21224840  
  7. Dotson JL, Crandall W, Mousa H, Honegger JR, Denson L, Samson C, Cunningham D, Balint J, Dienhart M, Jaggi P, Carvalho R. Presentation and outcome of histoplasmosis in pediatric inflammatory bowel disease patients treated with antitumor necrosis factor alpha therapy: a case series. Inflamm Bowel Dis. 2011;17(1):56-61. doi:10.1002/ibd.21378  PMID:20645322  
  8. Han X, Gilbert S, Groschwitz K, Hogan S, Jurickova I, Trapnell B, Samson C, Gully J. Loss of GM-CSF signalling in non-haematopoietic cells increases NSAID ileal injury. Gut. 2010;59(8):1066-78. doi:10.1136/gut.2009.203893  PMID:20584783  
  9. Han X, Uchida K, Jurickova I, Koch D, Willson T, Samson C, Bonkowski E, Trauernicht A, Kim MO, Tomer G, Dubinsky M, Plevy S, Kugathsan S, Trapnell BC, Denson LA. Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease. Gastroenterology. 2009;136(4):1261-71, e1-3. doi:10.1053/j.gastro.2008.12.046  PMID:19230854  
  10. Black D, Bird MA, Samson CM, Lyman S, Lange PA, Schrum LW, Qian T, Lemasters JJ, Brenner DA, Rippe RA, Behrns KE. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. J Hepatol. 2004;40(6):942-51. doi:10.1016/j.jhep.2004.02.031  PMID:15158334  
  11. Black D, Bird MA, Hayden M, Schrum LW, Lange P, Samson C, Hatano E, Rippe RA, Brenner DA, Behrns KE. TNF alpha-induced hepatocyte apoptosis is associated with alterations of the cell cycle and decreased stem loop binding protein. Surgery. 2004;135(6):619-28. doi:10.1016/j.surg.2003.11.004  PMID:15179368  
  12. Lange PA, Samson CM, Bird MA, Hayden MA, Behrns KE. Cirrhotic hepatocytes exhibit decreased TGFbeta growth inhibition associated with downregulated Smad protein expression. Biochem Biophys Res Commun. 2004;313(3):546-51. PMID:14697224  
  13. Bird MA, Black D, Lange PA, Samson CM, Hayden M, Behrns KE. NFkappaB inhibition decreases hepatocyte proliferation but does not alter apoptosis in obstructive jaundice. J Surg Res. 2003;114(2):110-7. PMID:14559434  
  14. Samson CM, Schrum LW, Bird MA, Lange PA, Brenner DA, Rippe RA, Behrns KE. Transforming growth factor-beta1 induces hepatocyte apoptosis by a c-Jun independent mechanism. Surgery. 2002;132(3):441-9. PMID:12324757  
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Children's Hospital St. Louis
Children's Discovery Institute
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