Jennifer N. Avari Silva, M.D.

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Professor of Pediatrics, Cardiology
Director, Pediatric Electrophysiology
College of Arts & SciencesSchool of MedicineCardiology

phone: (314) 454-6095


  • BA, Union College1997
  • BA, Wellcome Institute for the History of Medicine, The Netherlands Institute of the Health Sciences in conjunction with Nijmegen University, and Semmelweis University1994
  • MD, St. George's University School of Medicine2002


  • Residency in Pediatrics, Miami Children's Hospital2002 - 2005
  • Fellowship in Pediatric Cardiology, Washington University School of Medicine/St. Louis Children's Hospital2005 - 2008
  • Fellow, Rudy Lab in Biomedical Engineering, Washington University in St Louis2006 - 2008
  • 4th year Advanced Fellowship in Pediatric and Adult Congenital Electrophysiology, Children's Hospital Boston/Harvard Medical School2008 - 2009
  • Leadless Pacemaker Implant, Medtronic, Inc2018 - 2018

Licensure and Board Certification

  • 2002 - PresECFMG
  • 2005 - PresDiplomate, American Board of Pediatrics, General Pediatrics Certification
  • 2009 - PresMO, BNDD
  • 2009 - PresMO, DEA
  • 2009 - PresMO, Missouri Board of Medicine
  • 2009 - PresMissouri Board of Medicine, Controlled Medication License
  • 2009 - PresMO, Missouri State Board of Registration for the Healing Arts
  • 2009 - PresIL, Illinois Department of Financial and Professional Regulation
  • 2009 - PresIL, Illinois Department of Financial and Professional Regulation, Controlled Substance License
  • 2010 - PresIL, Department of Financial and Professional Regulation Divisional of Professional Regulation
  • 2012 - PresDiplomate, American Board of Pediatrics, Pediatric Cardiology Certification
  • 2015 - 2025International Board of Heart Rhythm Examiners, Certified Electrophysiology Specialist--Pediatric Cardiology, certificate #: 192745
  • 2021 - PresKS, Telemedicine Waiver Medical License

Honors and Awards

  • Best Poster, 18th Annual HHS SBIR/STTR Conference2016
  • Fellow, Heart Rhythm Society2016 - Pres
  • Fellow, American Heart Association2018 - Pres
  • Founder Nomination, Tech Startup Readiness Project, Ball State University and Indiana University2019
  • Innovator Award (Skandy Award), Skandalaris Center for Interdisciplinary Innovation and Entrepreneurship2019
  • World Zoroastrian Entrepreneur, World Zarathushti Chamber of Commerce2019
  • Finalist (Deamer Category), LaunchCode’s Moonshot Awards2019
  • Top Doctor, St Louis Magazine2019 - Pres
  • Fellow, American College of Cardiology2020 - Pres
  • IDEA Award for Design Interaction2020
  • Silver Prize, Edison Award 2021 in Surgical Visualization Platforms (Science, Medical and Dental)2021
  • Senior Member, National Academy of Inventors2022 - Pres

Recent Publications view all (80)

Publication Co-Authors

  1. Assessment of Apple Watch Series 6 pulse oximetry and electrocardiograms in a pediatric population. PLOS Digital Health. 2022;1(8):e0000051.  
  2. Direct to Consumer Wearables for Children: Who, What, When and How? 2022. 
  3. Early Preclinical Experience of a Mixed Reality Ultrasound System with Active GUIDance for NEedle-Based Interventions: The GUIDE Study Cardiovasc Digit Health J. 2022. doi:10.1016/j.cvdhj.2022.07.072  
  4. Electroconvulsive therapy in an adolescent with major depressive disorder and pre-existing arrhythmogenic right ventricular cardiomyopathy The Journal of ECT. 2022;10.1097:1-2. doi:10.1097/YCT.0000000000000875  
  5. Expanding Telehealth through Technology: Use of Digital Health Technologies during Pediatric Electrophysiology Telehealth Visits Cardiovasc Digit Health J. 2022. doi:  
  6. A Single Center Experience Comparing First versus Second Generation Insertable Cardiac Monitors in Pediatric Patients JICRM. 2022;13(6):1-9. doi:10.19102/icrm.2022.130605  PMCID:PMC9221184  PMID:35765585 
  7. Intravenous Sotalol Use In Pediatric And Congenital Heart Patients: A Multicenter Registry Study JAHA. 2022. doi:  PMID:35491986 
  8. Evaluation Challenges for the Application of Extended Reality Devices in Medicine JDI. 2022. doi:  
  9. Use of aminocaproic acid with bivalirudin for hemostatic management of abdominal surgery for neonate on ECMO ASAIO. 2022. doi:10.1097/MAT.0000000000001736  PMID:35439195 
  10. Implementation and Early Experience of a Pediatric Electrophysiology Telehealth Program Cardiovasc Digit Health J. 2022. doi:10.1016/j.cvdhj.2021.12.004  
  11. Children Really Are Not Little Adults: What We Can Take Away from the 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices Heart Rhythm O2. 2021. doi:  
  12. Incorporation of the CardioMEMS(TM) System during an Exercise Physiology Test in a Pediatric Congenital Heart Disease Patient Contributing to Medical Decision Making Pediatr Cardiol. 2021. doi:  
  13. Virtual and augmented reality in cardiovascular care: State of the art and future perspectives JACC: Cardiovascular Imaging. 2021. doi:  
  14. 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients Cardiol Young. 2021;2:1-104. doi:doi: 10.1017/S1047951121003413  PMID:34338183 
  15. 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients: Executive Summary Heart Rhythm. 2021. doi:  
  16. 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients Heart Rhythm. 2021. doi:  
  17. 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients Indian Pacing Electrophysiol J . 2021;S0972-6292(21):00115-7. doi:doi: 10.1016/j.ipej.2021.07.005  PMID:34333141 
  18. 2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients: Executive Summary Indian Pacing Electrophysiol J . 2021;S0972-6292(21):00116-9. doi:doi: 10.1016/j.ipej.2021.07.006  PMID:34333142 
  19. Design Considerations for Interacting and Navigating with 2 Dimensional and 3 Dimensional Medical Images in Virtual, Augmented and Mixed Reality Medical Applications Virtual, Augmented and Mixed Reality. Industrial and Everyday Life Applications. HCII 2021. Lecture Notes in Computer Science. 2021;LNCS 12770 :1-17. doi:  
  20. Sex and Race Disparities in Presumed Sudden Cardiac Death--One Size Does Not Fit All Circ: A&E. 2021;14(5). doi:DOI: 10.1161/CIRCEP.121.010053  PMID:33993706 
  21. The Future of Electrophysiology: Using Mixed Reality During Cardiac Ablation Procedures EP Lab Digest. 2021;21(5):1-2. 
  22. Impact of Augmented Reality Improvement in Ablation Catheter Navigation as Assessed by Virtual-Heart Simulation of Ventricular Tachycardia Ablation Computers in Biology and Medicine. 2021;133:104366. doi:10.1016/j.compbiomed.2021.104366  PMID:33836448 
  23. Comparing Patient and Family Usability of Insertable Cardiac Monitors in a Pediatric Cohort: Patient External Activator Versus Smartphone Transmission Heart Rhythm O2. 2021. doi:  
  24. A unique cardiovascular presentation of pheochromocytoma SAGE Open Medical Case Reports. 2021;9:2050313X21994037. doi:10.1177/2050313X2199403  PMCID:PMC7900786  PMID:33680468 
  25. The Impact of Direct to Consumer Wearables in Pediatric Electrophysiology Telehealth Clinics: A Real-World Case Series Cardiovasc Digit Health J. 2020;1(3):169-171. doi:10.1016/j.cvdhj.2020.09.005  PMCID:PMCID 7538375  PMID:33043315 
  26. Digital Health and the Care of the Arrhythmia Patient; What Every Electrophysiologist Needs to Know Circ Arrhythm Electrophysiol . 2020;12(11):e007953. doi:10.1161/CIRCEP.120.007953  PMID:33021815 
  27. Institutional experience of healthy pediatric patients presenting with atrial fibrillation who had an electrophysiology study J Card Surg. 2020;35(5):1004-1009. doi:10.1111/jocs.14506  PMID:32163635 
  28. Development and Human Factors Considerations for Extended Reality Applications in Medicine: The Enhanced ELectrophysiology Visualization and Interaction System (ĒLVIS) Virtual, Augmented and Mixed Reality. Industrial and Everyday Life Applications. HCII 2020. Lecture Notes in Computer Science. 2020;12191:341-356. doi:  
  29. First-In-Human Use of a Mixed Reality Display During Cardiac Ablation Procedures JACC: Clinical Electrophysiology. 2020;6(8):1023-1025. doi:DOI: 10.1016/j.jacep.2020.04.036  PMCID:PMC7743819  PMID:32819517 
  30. Performance Evaluation of Mixed Reality Display for Guidance during Transcatheter Cardiac Mapping and Ablation. IEEE J Transl Eng Health Med. 2020;(3):1-10. doi:10.1109/JTEHM.2020.3007031  PMCID:PMC7390021  PMID:32742821 
  31. Successful Institutional Development of a Pediatric Exercise Stress Testing Program after the Establishment of a Dedicated Exercise Team Journal of Exercise Physiology Online. 2020;23(3):38+. 
  32. Use of Extended Realities in Cardiology Trends Cardiovasc Med. 2020;30(3):143-148. PMCID:PMC6917970  PMID:31076168 
  33. Catheter Ablation in Pediatric Congenital Heart Disease: A Modern Perspective Circ Arrhythm Electrophysiol . 2019;12(11):e008019. doi:DOI: 10.1161/CIRCEP.119.008019  PMID:31722542 
  34. Extended Reality In Medical Practice Curr Treat Options Cardiovasc Med. 2019;21(4):18. doi:DOI: 10.1007/s11936-019-0722-7  PMCID:PMC6919549  PMID:30929093 
  35. What have we learned in the last 20 years? A Comparison of a Modern Era Pediatric and Congenital Catheter Ablation Registry to Prior Pediatric Ablation Registries Heart Rhythm. 2019;16(1):57-63. doi:DOI: 10.1016/j.hrthm.2018.08.013  PMID:30118886 
  36. Can smartphone wireless ECGs be used to accurately assess ECG intervals in pediatrics? A comparison of mobile health monitoring to standard 12-lead ECG PLoS One . 2018;13(9):e0204403. doi:DOI: 10.1371/journal.pone.0204403  PMCID:PMC6160047  PMID:30260996 
  37. Emerging Applications of Virtual Reality in Cardiovascular Medicine JACC Basic Transl Sci. 2018;3(3):420-430. doi:DOI: 10.1016/j.jacbts.2017.11.009  PMCID:PMC6058998  PMID:30062228 
  38. Coronary sinus morphology in pediatric patients with supraventricular tachycardia J Interv Card Electrophysiol. 2018;51(2):163-168. doi:DOI: 10.1007/s10840-018-0323-5  PMID:29397525 
  39. Atrioventricular Nodal Reentrant Tachycardia in Patients With Congenital Heart Disease Outcome After Catheter Ablation Cric A&E. 2017;10(7):e004896. doi:DOI: 10.1161/CIRCEP.116.004869  PMID:28687669 
  40. Reveal LINQ Versus Reveal XT Implantable Loop Recorders: Intra- and Post-Procedural Comparison. J Pediatr. 2017;187:290-294. doi:DOI: 10.1016/j.jpeds.2017.04.057  PMID:28545873 
  41. Force-Sensing Catheters During Pediatric Radiofrequency Ablation: The FEDERATION Study. JAHA. 2017;6(5):e005772. doi:DOI: 10.1161/JAHA.117.005772  PMCID:PMC5524110  PMID:28515113 
  42. Use of intravenous sotalol in newborns with supraventricular tachycardia. HeartRhythm Case Rep. 2017;3(7):332-335. doi:DOI: 10.1016/j.hrcr.2017.03.010  PMCID:PMC5511985  PMID:28748138 
  43. A Clinical Risk Score to Improve the Diagnosis of Tachycardia-Induced Cardiomyopathy in Childhood. Am J Cardiol. 2016;118(7):1074-80. doi:DOI: 10.1016/j.amjcard.2016.07.008  PMID:27515893 
  44. Percutaneous Pulmonary Valve Implantation Alters Electrophysiologic Substrate J Am Heart Assoc. 2016;5(10):e004325. doi:DOI: 10.1161/JAHA.116.004325  PMCID:PMC5121524   PMID:27694326 
  45. Implantable Loop Recorder Monitoring for Refining Management of Children With Inherited Arrhythmia Syndromes. J Am Heart Assoc. 2016;5(6):e003632. doi:DOI: 10.1161/JAHA.116.003632  PMCID:PMC4937287  PMID:27231019 
  46. Use of Smartphone Technology in Cardiology Trends Cardiovasc Med. 2016;26(4):376-86. doi:DOI: 10.1016/j.tcm.2015.11.002  PMID:26686266 
  47. Atrial Tachycardia in an Electrically Dissociated Native Right Atrium after Heart Transplantation. HeartRhythm Case Rep. 2016;2(4):356-359. doi:DOI: 10.1016/j.hrcr.2016.04.004  PMCID:PMC5419896  PMID:28491709 
  48. The incidence of chromosome abnormalities in neonates with structural heart disease Heart. 2016;102(8):634-7. doi:DOI: 10.1136/heartjnl-2015-308650  PMID:26843533 
  49. SPEAR Trial: Smartphone Pediatric ElectrocARdiogram Trial. PLoS One. 2015;10(8):e0136256. doi:DOI: 10.1371/journal.pone.0136256  PMCID:PMC4546652  PMID:26295569 
  50. Corrected QT prolongation and bradycardia during therapeutic hypothermia in an infant: a case report NeoReviews. 2015. 
  51. Cardiac electrophysiological substrate underlying the ECG phenotype and electrogram abnormalities in Brugada syndrome patients. Circulation. 2015;131(22):1950-9. doi:DOI: 10.1161/CIRCULATIONAHA.114.013698  PMCID:PMC4452400  PMID:25810336 
  52. Electrophysiologic substrate in congenital Long QT syndrome: noninvasive mapping with electrocardiographic imaging (ECGI). Circulation. 2014;130(22):1936-1943. doi:DOI: 10.1161/CIRCULATIONAHA.114.011359  PMCID:PMC4245321  PMID:25294783 
  53. Commentary Clin Chem. 2014;60(9):1156. doi:DOI: 10.1373/clinchem.2014.226241  PMID:25170165 
  54. Lead Advancement in Pediatric Patients with SelectSecure 3830 Pacing Leads J Cardiol Curr Res. 2014;1(3):75. doi:DOI: 10.15406/jccr.2014.01.00015  
  55. Predictors of myocardial recovery in pediatric tachycardia-induced cardiomyopathy. Heart Rhythm. 2014;11(7):1163-9. doi:DOI: 10.1016/j.hrthm.2014.04.023  PMID:24751393 
  56. Management of pediatric tachyarrhythmias on mechanical support. Circ Arrhythm Electrophysiol. 2014;7(4):658-663. doi:DOI: 10.1161/CIRCEP.113.000973  PMID:24987047 
  57. Assessment of intrathoracic impedance algorithm in the pediatric and adult congenital population. Pacing Clin Electrophysiol. 2014;37(9):1174-80. doi:DOI: 10.1111/pace.12372  PMID:24646399 
  58. Duplication of 20p12.3 associated with familial Wolff-Parkinson-White syndrome. Am J Med Genet A. 2013;161A(1):137-44. doi:DOI: 10.1002/ajmg.a.35701  PMID:23239491 
  59. Updates on the inherited cardiac ion channelopathies: from cell to clinical. Curr Treat Options Cardiovasc Med. 2012;14(5):473-89. doi:10.1007/s11936-012-0198-1  PMID:22865245 
  60. 3:2 antegrade atrioventricular block with AV nodal reentrant tachycardia: what is the mechanism and where is the block? Pacing Clin Electrophysiol. 2012;35(7):877-9. doi:10.1111/j.1540-8159.2012.03420.x  PMID:22553974 
  61. Unusually high association of hypertrophic cardiomyopathy and complex heart defects in children with fasciculoventricular pathways. Pacing Clin Electrophysiol. 2012;35(3):308-13. doi:10.1111/j.1540-8159.2011.03274.x  PMID:22242628 
  62. Congenital long QT 3 in the pediatric population Am J Cardiol. 2012;109(10):1459-65. doi:DOI: 10.1016/j.amjcard.2012.01.361  PMID:22360817 
  63. Electrophysiologic substrate and intraventricular left ventricular dyssynchrony in nonischemic heart failure patients undergoing cardiac resynchronization therapy. Heart Rhythm. 2011;8(5):692-9. doi:10.1016/j.hrthm.2011.01.017  PMCID:PMC3096066  PMID:21232630 
  64. Outcomes of heart transplantation using donor hearts from infants with sudden infant death syndrome. J Heart Lung Transplant. 2010;29(11):1226-30. doi:10.1016/j.healun.2010.06.004  PMID:20691612 
  65. Use of a wearable automated defibrillator in children compared to young adults. Pacing Clin Electrophysiol. 2010;33(9):1119-24. doi:10.1111/j.1540-8159.2010.02819.x  PMID:20561227 
  66. Cryoablation with an 8-mm tip catheter for pediatric atrioventricular nodal reentrant tachycardia is safe and efficacious with a low incidence of recurrence. Pacing Clin Electrophysiol. 2010;33(6):681-6. doi:10.1111/j.1540-8159.2010.02706.x  PMID:20230479 
  67. Current management of pediatric dilated cardiomyopathy. Curr Opin Cardiol. 2010;25(2):80-7. doi:10.1097/HCO.0b013e328335b220  PMID:20019605 
  68. Management of postoperative pediatric cardiac arrhythmias: current state of the art. Curr Treat Options Cardiovasc Med. 2009;11(5):410-6. doi:DOI: 10.1007/s11936-009-0043-3  PMID:19846040 
  69. Cardiac resynchronization therapy in pediatric congenital heart disease: insights from noninvasive electrocardiographic imaging. Heart Rhythm. 2009;6(8):1178-85. doi:DOI: 10.1016/j.hrthm.2009.04.017  PMCID:PMC2717033  PMID:19632630 
  70. Pediatric non post-operative junctional ectopic tachycardia medical management and interventional therapies. J Am Coll Cardiol. 2009;53(8):690-7. doi:10.1016/j.jacc.2008.11.019  PMID:19232902 
  71. Hypertrophic cardiomyopathy with preexcitation: insights from noninvasive electrocardiographic imaging (ECGI) and catheter mapping. J Cardiovasc Electrophysiol. 2008;19(11):1215-7. doi:10.1111/j.1540-8167.2008.01203.x  PMCID:PMC2631093  PMID:18479334 
  72. Cardiac resynchronization therapy for pediatric heart failure. Heart Rhythm. 2008;5(10):1476-8. doi:10.1016/j.hrthm.2008.05.024  PMID:18672406 
  73. Cardiac memory in patients with Wolff-Parkinson-White syndrome: noninvasive imaging of activation and repolarization before and after catheter ablation. Circulation. 2008;118(9):907-15. doi:10.1161/CIRCULATIONAHA.108.781658  PMCID:PMC2747627  PMID:18697818 
  74. Markers of coronary sinus accessory pathways in pediatrics. Pacing Clin Electrophysiol. 2008;31(8):968-73. doi:10.1111/j.1540-8159.2008.01123.x  PMID:18684252 
  75. Noninvasive electrocardiographic imaging (ECGI) of epicardial activation before and after catheter ablation of the accessory pathway in a patient with Ebstein anomaly. Heart Rhythm. 2008;5(6):857-60. doi:10.1016/j.hrthm.2008.03.011  PMCID:PMC2967218  PMID:18482872 
  76. Noninvasive electrocardiographic imaging (ECGI) of a univentricular heart with Wolff-Parkinson-White syndrome. Heart Rhythm. 2008;5(4):605-8. doi:10.1016/j.hrthm.2007.12.018  PMCID:PMC2329801  PMID:18325851 
  77. Experience and results during transition from radiofrequency ablation to cryoablation for treatment of pediatric atrioventricular nodal reentrant tachycardia. Pacing Clin Electrophysiol. 2008;31(4):454-60. doi:10.1111/j.1540-8159.2008.01033.x  PMID:18373764 
  78. Electrocardiographic diagnosis of myocardial ischemia in children: is a diagnostic electrocardiogram always diagnostic? Pediatrics. 2007;120(2):440-4. doi:10.1542/peds.2007-0170  PMID:17671071 
  79. Diagnosis and Treatment of Fetal Tachyarrhythmias US Cardiology. 2006;35(2):1-5. 
  80. Using Holograms to Guide Intra-Procedural Navigation in the Cardiac Catheterization Lab US Card Review. 
Last updated: 11/10/2022
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