Department of Pediatrics

Education

• BS, cum laude, Tulane University, 2003
• MD, University of Texas Medical Branch at Galveston, 2008
• MSCI, Washington University in St. Louis, 2014

Training

• Resident Physician, St. Louis Children's Hospital, 2008 - 2011
• Clinical Fellow, Washington University in St. Louis, 2011 - 2014

Licensure and Board Certification

• 2012 - 2022General Pediatrics Board Certified
• 2013 - PresMO, Missouri Medical License
• 2015 - 2025Pediatric Hematology/Oncology

Honors and Awards

• Institute of Clinical and Translational Science Research Forum for Child Health Supplemental Funding Award (NCATS UL1TR000448), 2015
• American Society of Hematology Clinical Research Training Institute Participant, 2016
• American Society of Hematology Advocacy Leadership Institute, 2017
• Key Opinion Leader for Sickle Cell Disease Poster Walk at the 2020 American Society of Hematology Annual Meeting, 2020
• Mentor, External Mentorship Pilot Program in Non-Malignant Hematology in ASH Medical Education Institute, 2021 - 2022
• NHLBI Hope for Sickle Cell Disease Challenge - First Place, 2021
• Key Opinion Leader for Sickle Cell Disease Poster Walk at the 2021 American Society of Hematology Annual Meeting, 2021

Recent Publications view all (22)

Publication Co-Authors

Ronald Jackups, Jr., M.D., Ph.D.

Monica Hulbert, M.D.

Allison King, M.D., M.P.H., Ph.D.

Slim Fellah

Kristin Guilliams, MD MSCI

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Fields, Melanie

1. Ramos K, Guilliams KP, Fields ME. The Development of Neuroimaging Biomarkers for Cognitive Decline in Sickle Cell Disease Hematology/Oncology Clinics of North America. 2022;36:1167-1186. 
2. Mahdi J, Bach A, Smith AE, Tomko SR, Fields ME, Griffith JL, Morris SM, Guerriero RM, Noetzel MJ, Guilliams KP, Agner SC. Stroke Mimics Are Not Benign in Immunocompromised Children. Stroke. 2022;101161STROKEAHA122039311. PMID:35862209 
3. Wang Y, Guilliams KP, Fields ME, Fellah S, Binkley MM, Reis M, Vo KD, Chen Y, Ying C, Blinder M, King AA, Hulbert ML, An H, Lee JM, Ford AL. Silent Infarcts, White Matter Integrity, and Oxygen Metabolic Stress in Young Adults With and Without Sickle Cell Trait. Stroke. 2022;101161STROKEAHA121036567. PMID:35545940 
4. Ouyang A, Gadiraju M, Gadiraju V, Power L, Gadiraju V, Liu G, Guilliams KP, Binkley MM, Badawy SM, Fields ME. GRAPES: Trivia game increases sickle cell disease knowledge in patients and providers and mitigates healthcare biases. Pediatr Blood Cancer. 2022;e29717. PMID:35441455 
5. Wilson DB, Fields ME. With age comes resilience. Blood. 2022;139(15):2266-2268. PMID:35420686 
6. Fields ME, Mirro AE, Binkley MM, Guilliams KP, Lewis JB, Fellah S, Chen Y, Hulbert ML, An H, Ford AL, Lee JM. Cerebral oxygen metabolic stress is increased in children with sickle cell anemia compared to anemic controls. Am J Hematol. 2022. PMID:35113471 
7. Mayer SL, Fields ME, Hulbert ML. Neurologic and Cognitive Outcomes in Sickle Cell Disease from Infancy through Adolescence. Neoreviews. 2021;22(8):e531-e539. PMID:34341160 
8. Wang Y, Fellah S, Fields ME, Guilliams KP, Binkley MM, Eldeniz C, Shimony JS, Reis M, Vo KD, Chen Y, Lee JM, An H, Ford AL. Cerebral Oxygen Metabolic Stress, Microstructural Injury, and Infarction in Adults With Sickle Cell Disease. Neurology. 2021. PMID:34172536 
9. Eldeniz C, Binkley MM, Fields ME, Guilliams KP, Ragan DK, Comiskey L, Chen Y, Lee J-M, Ford AL, An H.. Bulk Volume Susceptibility Difference Between Deoxyhemoglobin and Oxyhemoglobin for HbA and HbS: A Comparative Study Magnetic Resonance in Medicine. 2021;85(6):3383-3393. PMID:33475200 
10. Fields ME, Mirro AE, Guilliams KP, Binkley MM, Gil Diaz L, Tan J, Fellah S, Eldeniz C, Chen Y, Ford AL, Shimony JS, King AA, An H, Smyser CD, Lee JM. Functional Connectivity Decreases with Metabolic Stress in Sickle Cell Disease. Ann Neurol. 2020;88(5):995-1008. PMCID:PMC7592195  PMID:32869335 
11. Fields ME. Personalizing transfusion in sickle cell disease: where is the canary in the mine? Transfusion. 2019;59(8):2493-2495. PMID:31374145 
12. Hood AM, King AA, Fields ME, Ford AL, Guilliams KP, Hulbert ML, Lee JM, White DA. Higher executive abilities following a blood transfusion in children and young adults with sickle cell disease. Pediatr Blood Cancer. 2019;66(10):e27899. doi:10.1002/pbc.27899  PMCID:PMC6707832  PMID:31267645 
13. Fields ME, Guilliams KP, Ragan D, Binkley MM, Mirro A, Fellah S, Hulbert ML, Blinder M, Eldeniz C, Vo K, Shimony JS, Chen Y, McKinstry RC, An H, Lee JM, Ford AL. Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia. Blood. 2019. PMID:30858231 
14. Guilliams KP, Fields ME, Dowling MM. Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease. Stroke. 2019;50(2):266-273. PMCID:PMC6385587  PMID:30661504 
15. Ford AL, Ragan DK, Fellah S, Binkley MM, Fields ME, Guilliams KP, An H, Jordan LC, McKinstry RC, Lee JM, DeBaun MR. Silent infarcts in sickle cell anemia occur in the borderzone region and are associated with low cerebral blood flow. Blood. 2018. PMID:30061156 
16. Fields ME, Guilliams KP, Ragan DK, Binkley MM, Eldeniz C, Chen Y, Hulbert ML, McKinstry RC, Shimony JS, Vo KD, Doctor A, An H, Ford AL, Lee JM. Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease. Neurology. 2018. PMID:29500287 
17. Guilliams KP, Fields ME, Ragan DK, Eldeniz C, Binkley MM, Chen Y, Comiskey LS, Doctor A, Hulbert ML, Shimony JS, Vo KD, McKinstry RC, An H, Lee JM, Ford AL. Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia. Blood. 2017. PMID:29255068 
18. Guilliams KP, Fields ME, Ragan DK, Chen Y, Eldeniz C, Hulbert ML, Binkley MM, Rhodes JN, Shimony JS, McKinstry RC, Vo KD, An H, Lee JM, Ford AL.. Large-Vessel Vasculopathy in Children with Sickle Cell Disease: Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy Pediatric Neurology. 2016. PMID:28159432 
19. Fields ME, Hoty-Drazen C, Abel R, Rodeghier MJ, Yarboi JM, Compas BE, King AA. A Pilot Study of Parent Education Intervention Improves Early Childhood Development Among Toddlers with Sickle Cell Disease Pediatric Blood & Cancer. 2016;63(12):2131-2138. PMID:27509845 
20. Fields ME, Hulbert ML, Chen L, Berlin AN, Jackups R, Spinella, PC. Red Blood Cell Storage Duration is Not Associated with Clinical Outcomes for Acute Chest Syndrome in Children with Sickle Cell Disease Transfusion. 2015. PMID:26033266 
21. Guilliams KP, Fields ME, Hulbert ML. Higher-than-expected prevalence of silent cerebral infarcts in children with hemoglobin SC disease Blood. 2015;125(2):416. PMID:25573975 
22. ML Hulbert, ME Fields, KP Guilliams, P Bijlani, S Shenoy, S Fellah, AS Towerman, MM Binkley, RC McKinstry, JS Shimony, Y Chen, C Eldeniz, DK Ragan, K Vo, H An, J-M Lee, AL Ford. Normalization of cerebral hemodynamics following hematopoietic stem cell transplant in children with sickle cell disease Blood.