Dr. Remy is an Associate Professor and NIH funded physician-scientist at Washington University in St. Louis in the Departments of Pediatrics and Internal Medicine, and an international expert in adult and pediatric sepsis. As an adult and pediatric critical care physician, his laboratory is focused on two areas: heme-based trafficking and signaling in immune dysregulation in context of diseases of intravascular hemolysis (COVID, sepsis, malaria, sickle cell disease, thalassemia) and after red blood cell transfusion; and real time immunophenotyping of pro and hypoinflammatory states to identify timing for immunoadjuvant therapies.During the COVID-19 pandemic, Dr. Remy has cared for over fifteen hundred patients in the adult and pediatric ICU while pivoting his laboratory activities to understanding the evolution of the disease in both a hematologic and immune functional approach. Dr. Remy in collaboration with Dr. Richard Hotchkiss were among the first in world to demonstrate a covid-19 immunosuppressive phenotype demonstrating significant T cell exhaustion in patients with critical illness. Dr. Remy's first authored manuscript on care of adults in the pediatric ICU was the featured article in Pediatric Critical Care Medicine. He has been featured on a number of news programs including CNN, CBS Evening News, BBC News, People Magazine, NBC News, Reuters, USA today, and many other local and international news stations on his experiences during this pandemic and speaking on the immunologic consequences of disease, pediatric multisystem inflammatory syndrome (MIS-C), public health measures and schools, and potential therapies for SARS-CoV-2 infection. Dr. Remy sits on a number of national and international task forces in sepsis and COVID including the NIH, BARDA, FDA, CDC, and many others. Dr. Remy has authored over 75 peer reviewed manuscripts, textbook chapters, and invited commentaries. He is the chair of the basic and translational science research section for the society of critical care medicine (SCCM); the largest society for critical care practitioners in the world with over 25,000 members. Additionally, he is the immunology chair for the pediatric acute lung injury and sepsis investigators blood network, and holds key leadership positions in many other organizations including executive committee of the research section of SCCM and member at large for the Internal Medicine section of SCCM. He has been honored as a fellow in the American College of Critical Care Medicine and fellow in the society of Pediatric Research.
Prior to Washington University: Dr. Remy holds a Medical Degree from Jefferson Medical College and Masters’ Degrees from Duke University (Clinical Research) and Washington University in St. Louis (Translational Research; immunology focus). He completed dual residencies in Internal Medicine and Pediatrics at Case Western University/University Hospitals of Cleveland/Rainbow Babies and Children’s Hospital in Cleveland, Ohio, Pediatric Critical Care fellowship at New York Presbyterian Hospital-Columbia University in New York City, and Adult Critical Care Fellowship at the National Institutes of Health in Bethesda, MD. He is quadruple boarded in each of these specialties. Additionally, he is formally trained in Global Health and emergency and disaster preparedness; and has received a certificate of clinical research from the National Institutes of Health. He is also the medical director (ICU captain) for Heart Care International’s Medical Missions and global health chair for the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Dr. Remy’s has clinical interests in both adults and children in bioethics, international health, humor therapy, and palliative care. Previous research has been in calcium activated chloride channels in airway smooth muscle and in therapeutics to bacillus anthracis induced shock. His research interests are in host inflammatory response in sepsis.