Matthew I. Goldsmith, M.D.

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Professor of Pediatrics, Critical Care Medicine
Critical Care Medicine

phone: (314) 454-2527

Clinical Interests

Dr. Goldsmith is an Assistant Professor of Pediatrics and Genetics, He is an attending physician in the Division of Critical Care Medicine and a member of the Developmental Biology and Genetics Unit. Dr. Goldsmith received his medical degree from the University of Toronto. He did his residency and fellowship at Washington University School of Medicine and Saint Louis Children's Hospital. Dr. Goldsmith joined the faculty of the Department of Pediatrics at Washington University School of Medicine in 2002. He is board certified in pediatrics and in pediatric critical care medicine. He is a member of the Society for Critical Care Medicine.


  • BSc, University of Toronto1987
  • MSc, University of Toronto1990
  • MD, University of Toronto1995


  • Resident, Pediatrics, St. Louis Children's Hospital1995 - 1998
  • Chief Resident, Pediatrics, St. Louis Children's Hospital1998 - 1999
  • Fellow, Pediatric Critical Care Medicine, Washington University School of Medicine/St. Louis Children's Hospital1999 - 2002
  • Solutions for Patient Safety, St. Louis Children's Hospital2014
  • Program for Leading Innovation in Healthcare and Education, Harvard Macy Institute2015
  • Lean Leader Training, St. Louis Children's Hospital2015
  • Academic Medical Leadership Program for Physicians and Scientists, Washington University School of Medicine/Olin Business School/BJC Healthcare2017
  • Leadership Development for Physicians in Academic Health Centers, Harvard T.H. Chan School of Public Health2017

Licensure and Board Certification

  • 1996 - PresMO
  • 1999 - 2016Pediatrics
  • 2002 - PresPediatric Critical Care
  • 2014 - PresAdvanced Cardiac Life Support
  • 2014 - PresBasic Life Support
  • 2014 - PresPediatric Advanced Life Support
  • 2017 - PresPediatric Advanced Life Support Instructor

Honors and Awards

  • Ann Shepard Memorial Scholarship for Biology1986
  • Daniel Wilson Scholarship for Physiology/Biochemistry1986
  • Margaret J. Santalo Memorial Scholarship for Physiology1987
  • NSERC Summer Research Scholarship1987
  • University of Toronto Open Graduate Fellowship1988 - 1989
  • Ontario Graduate Scholarship1988 - 1990
  • MRC (Canada) Studentship1989 - 1990
  • Dr. R.E. Haist Award in Physiology1991 - 1992
  • Dean's Honor Roll in Medicine1991 - 1995
  • Dr. C.S. Wainwright Memorial Scholarship1992
  • Robert and Annie McDonnell Trust Fund Research Scholarship1992
  • MDS Scholarship in Laboratory Medicine1993
  • MRC (Canada) Summer Research Scholarship1993
  • Alpha Omega Alpha Honor Medical Society1994
  • Dr. Carl Witus Prize in Pediatrics1994
  • Merck Sharp and Dohme Award1994
  • Cody Gold Medal (graduated 1st overall, School of Medicine, class of 1995)1995
  • Ellen Mickle Fellowship1995
  • Pediatric Scientist Development Award2000 - 2003
  • HHMI Young Investigator Award2000 - 2004
  • Mallinckrodt Foundation Award2003 - 2006
  • Clinical Nutrition Research Unit Award2004 - 2005
  • Scholar of the Child Health Research Center of Excellence in Developmental Biology2004 - 2006
  • James Sutherland Award for Outstanding Research by a Young Investigator2006
  • Best Doctors in St. Louis2007 - Pres
  • Best Doctors in America2007 - Pres
  • Elected to Society for Pediatric Research2010
  • Faculty Member, F10002019
  • Doctor Honoris Causa, Riga Stradins University2019

Recent Publications view all (12)

Publication Co-Authors

  1. Kinesin family member 6 (kif6) is necessary for spine development in zebrafish. Dev Dyn. 2014;243(12):1646-57. doi:10.1002/dvdy.24208  PMID:25283277 
  2. Successful use of plasma exchange for profound hemolysis in a child with loxoscelism. Pediatrics. 2014;134(5):e1464-7. doi:10.1542/peds.2013-3338  PMID:25349320 
  3. MYBPC1 mutations impair skeletal muscle function in zebrafish models of arthrogryposis. Hum Mol Genet. 2013;22(24):4967-77. doi:10.1093/hmg/ddt344  PMCID:PMC3836476  PMID:23873045 
  4. A chemical screen to identify novel inhibitors of fin regeneration in zebrafish. Zebrafish. 2010;7(1):53-60. doi:10.1089/zeb.2009.0633  PMCID:PMC2946367  PMID:20384483 
  5. Severe ceftriaxone-induced hemolysis complicated by diffuse cerebral ischemia in a child with sickle cell disease. J Pediatr Hematol Oncol. 2009;31(11):870-2. doi:10.1097/MPH.0b013e3181b7eda2  PMID:19829151 
  6. A gain of function mutation causing skeletal overgrowth in the rapunzel mutant. Dev Biol. 2009;334(1):224-34. doi:10.1016/j.ydbio.2009.07.025  PMCID:PMC2756807  PMID:19632218 
  7. A developmental transition in growth control during zebrafish caudal fin development. Dev Biol. 2006;296(2):450-7. doi:10.1016/j.ydbio.2006.06.010  PMID:16844108 
  8. Saltatory control of isometric growth in the zebrafish caudal fin is disrupted in long fin and rapunzel mutants. Dev Biol. 2003;259(2):303-17. PMID:12871703 
  9. Mechanics of motility: distinct dynein binding domains on alpha- and beta-tubulin. Biochem Cell Biol. 1995;73(9-10):665-71. PMID:8714687 
  10. A unique tubulin antiserum attenuates the rate of poleward chromosome movement in anaphase. Eur J Cell Biol. 1992;58(2):346-55. PMID:1425771 
  11. Conserved beta-tubulin binding domain for the microtubule-associated motors underlying sperm motility and fast axonal transport. Cell Motil Cytoskeleton. 1991;20(3):249-62. doi:10.1002/cm.970200308  PMID:1723030 
  12. Separate non-cholinergic descending projections and cholinergic ascending projections from the nucleus tegmenti pedunculopontinus. Brain Res. 1988;445(2):386-91. PMID:2453253 
Last updated: 08/07/2020
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