Caroline C. Horner, M.D.

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Associate Professor of Pediatrics, Allergy and Pulmonary Medicine
Researcher, Patient Oriented Research Unit
Allergy and Pulmonary Medicine

phone: (314) 454-2694

Clinical Interests

Dr. Horner is a member of the Division of Allergy, Immunology and Pulmonary Medicine. She received her undergraduate degree in chemistry from Washington University. She received her medical degree from and completed a residency in Internal Medicine and Pediatrics at St. Louis University. She completed her Allergy/Immunology fellowship at the University of Texas Medical Branch in Galveston, TX. She joined the faculty of Washington University in 2006. She is board certified in Pediatrics, Internal Medicine, and Allergy and Clinical Immunology. Dr. Horner’s research interests include childhood asthma. She has held several leadership positions within the American Academy of Allergy, Asthma, & Immunology (AAAAI) and is a member of the Joint Task Force on Practice Parameters. She currently serves as the fellowship program director for Pediatric Allergy Immunology.


  • BA, universali cum honore, Washington University1993
  • MD, cum laude, St. Louis University School of Medicine2000
  • MSCI, Washington University School of Medicine2011


  • Medical Research Technician, Washington University School of Medicine and St. Louis University1994 - 1996
  • Summer Research Fellow, St. Louis University School of Medicine1997 - 1997
  • Resident, Internal Medicine & Pediatrics, St. Louis University School of Medicine2000 - 2004
  • Fellow, Allergy & Immunology, University of Texas Medical Branch2004 - 2006

Licensure and Board Certification

  • 2004 - PresAmerican Board of Internal Medicine
  • 2004 - PresAmerican Board of Pediatrics
  • 2006 - PresAmerican Board of Allergy and Immunology
  • 2006 - PresMO, Medical License
  • 2021 - PresIL Medical License

Honors and Awards

  • Medical School Class President, St. Louis University School of Medicine1998 - 2000
  • Alpha Omega Alpha, St. Louis University School of Medicine1999
  • Alpha Sigma Nu, National Jesuit honor society, St. Louis University School of Medicine1999
  • Merck Book Award, awarded for “significant contributions to the welfare of St. Louis University School of Medicine, its students, and its academic program”2000
  • Academic Fellowship Award, University of Texas Medical Branch2005
  • Nominee Outstanding Resident/Fellow Award, University of Texas Medical Branch2005
  • Nominee Outstanding Resident/Fellow Award, University of Texas Medical Branch2006
  • Clinical Research Training Center Postdoctoral Program Scholar, Washington University School of Medicine2008 - 2011
  • Gail G Shapiro Clinical Faculty Award, Allergy, Asthma & Immunology Education and Research Trust, American Academy of Allergy, Asthma & Immunology2010
  • NIH Loan Repayment Program Recipient2011 - 2014
  • Best Doctors in America® 2019 - 2020 List2019
  • Best Doctors in America® 2020 - 2021 List2020
  • Top Doctor, Castle Connolly Top Doctors®2021
  • Top Doctor, Castle Connolly Top Doctors®2022

Recent Publications view all (20)

Publication Co-Authors

  1. Topical Corticosteroids for Chronic Rhinosinusitis with Nasal Polyposis: GRADE Systematic Review and Network Meta-Analysis.Bognanni A, Chu DK, Rank MA, Bernstein J, Ellis AK, Golden D, Greenhawt M, Hagan JB, Horner CC, Ledford DK, Lieberman J, Luong AU, Marks LA, Orlandi RR, Samant SA, Shaker M, Soler ZM, Stevens WW, Stukus DR, Wang J, Peters AT. J Allergy Clin Immunol. 2022;S0091-6749(22)01050-8(2022 Aug 12). PMID:PMID: 35970310 
  2. Preventing asthma in high risk kids (PARK) with omalizumab: Design, rationale, methods, lessons learned and adaptation. Contemp Clin Trials. 2022;100:106228(2021 Jan). PMID:PMID: 33242697 
  3. The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and RecommendedEvaluation and Management: A Systematic Review, Meta-analysis, GRADE Assessment, and International Consensus Approach. J Allergy Clin Immunol Pract. 2021;Oct;9(10):3546-3567. doi:10.1016/j.jaip.2021.06.006  PMID:34153517 
  4. Immunological findings and clinical outcomes of infants with positive newborn screening for severe combined immunodeficiency from a tertiary care center in the U.S. Frontiers in Immunology. 2021. doi:doi: 10.3389/fimmu.2021.734096  
  5. Peanut Allergy Diagnosis- a 2020 Practice Parameter Update, Systematic Review, and GRADE Analysis J Allergy Clin Immunol. 2020;S0091-6749(20):31137-4. doi:10.1016/j.jaci.2020.07.031  PMID:32810515 
  6. Rhinitis 2020: A Practice Parameter Update J Allergy Clin Immunol. 2020;S0091-6749(20):31023-X. doi:10.1016/j.jaci.2020.07.007  PMID:32707227 
  7. Making the GRADE in anaphylaxis management: Toward recommendations integrating values, preferences, context, and shared decision making. Ann Allergy Asthma Immunol. 2020;124(6):526-535. doi:10.1016/j.anai.2020.03.009  PMID:32199979  
  8. Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis. J Allergy Clin Immunol. 2020;145(4):1082-1123. doi:10.1016/j.jaci.2020.01.017  
  9. Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. J Allergy Clin Immunol. 2019;143(5):1934-1937. doi:10.1016/j.jaci.2018.10.071  PMID:30660645 
  10. Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations. N Engl J Med. 2018;378(10):891-901. doi:10.1056/NEJMoa1710988  PMID:29504498  
  11. Administration of influenza vaccines to egg allergic recipients: A practice parameter update 2017. Ann Allergy Asthma Immunol. 2018;120(1):49-52. doi:10.1016/j.anai.2017.10.020  PMID:29273128 
  12. Treatment of seasonal allergic rhinitis: An evidence-based focused 2017 guideline update. Ann Allergy Asthma Immunol. 2017;119(6):489-511.e41. PMID:29103802 
  13. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016;375(7):619-30. doi:10.1056/NEJMoa1515990  PMID:27532828  
  14. Daily global stress is associated with nocturnal asthma awakenings in school-age children. J Allergy Clin Immunol. 2016. PMID:27246525 
  15. Most nocturnal asthma symptoms occur outside of exacerbations and associate with morbidity. J Allergy Clin Immunol. 2011;128(5):977-82.e1-2. doi:10.1016/j.jaci.2011.07.018  PMCID:PMC3408598  PMID:21855126 
  16. Diagnosis and management of asthma in preschool and school-age children: focus on the 2007 NAEPP Guidelines. Curr Opin Pulm Med. 2009;15(1):52-6. doi:10.1097/MCP.0b013e32831da8ea  PMID:19077706 
  17. Age-related changes in the asthmatic phenotype in children. Curr Opin Pediatr. 2007;19(3):295-9. doi:10.1097/MOP.0b013e32809913a2  PMID:17505189 
  18. Management approaches to intermittent wheezing in young children. Curr Opin Allergy Clin Immunol. 2007;7(2):180-4. doi:10.1097/ACI.0b013e32807fafd2  PMID:17351473 
  19. Protein kinase C acylation by palmitoyl coenzyme A facilitates its translocation to membranes. Biochemistry. 1998;37(34):11953-61. doi:10.1021/bi980565w  PMID:9718320 
  20. Accumulation of unsaturated acylcarnitine molecular species during acute myocardial ischemia: metabolic compartmentalization of products of fatty acyl chain elongation in the acylcarnitine pool. Biochemistry. 1996;35(24):7903-9. doi:10.1021/bi960552n  PMID:8672492 
Last updated: 09/12/2022
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