Mark C. Johnson, M.D.

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Professor of Pediatrics, Cardiology

phone: (314) 454-6095

Clinical Interests

Congenital heart diseasePediatric echocardiography3D echocardiographyHeart disease with Trisomy 21 syndrome


  • BA, Summa Cum Laude, University of Rochester1978
  • MD, Johns Hopkins University School of Medicine1982


  • Resident, , University of Colorado Health Science Center1982 - 1985
  • Fellow, Washington University School of Medicine, St. Louis Children's Hospital1990 - 1994

Licensure and Board Certification

  • MO, Missouri State Board of Registration for the Healing Arts
  • IL, Licensed Physician
  • 1986 - PresThe American Board of Pediatrics
  • 1996 - PresThe American Board of Pediatrics and its Subboard of Pediatric Cardiology

Honors and Awards

  • St. Louis Best Doctors, St. Louis Magazine2013 - Pres

Recent Publications view all (24)

Publication Co-Authors

  1. 3D Echocardiography Provides Highly Accurate 3D Printed Models in Congenital Heart Disease Pediatric Cardiology. 2021;42(1):131-141. PMID:33083888 
  2. Dichotomous roles of TBX3 in the establishment of atrioventricular conduction pathways in the human heart Heart Rhythm Case Reports. 2019;5:109-111. 
  3. Risk factors and prognostic significance of altered left ventricular geometry in preterm infants. J Perinatol. 2018. PMID:29410539 
  4. Normative Left Ventricular M-Mode Echocardiographic Values in Preterm Infants up to 2 kg. J Am Soc Echocardiogr. 2017. PMID:28599830 
  5. Coronary artery dilation and left ventricular hypertrophy do not predict morbidity in children with sickle cell disease. Pediatr Blood Cancer. 2015;62(1):115-119. doi:10.1002/pbc.25239  PMID:25264310 
  6. Tissue Doppler septal Tei index indicates severity of illness in pediatric patients with congestive heart failure. Pediatr Cardiol. 2014;35(3):411-8. doi:10.1007/s00246-013-0794-1  PMCID:PMC3944049  PMID:24061276 
  7. To-and-fro murmur in the young due to major congenital cardiac defects: is cardiac auscultation obsolete? Cardiol Young. 2010;20(6):707-8. doi:10.1017/S1047951110001393  PMID:20887646 
  8. Left ventricular hypertrophy and diastolic dysfunction in children with sickle cell disease are related to asleep and waking oxygen desaturation. Blood. 2010;116(1):16-21. 
  9. Primary pulmonary vein stenosis. Amer J Card. 2007;(99):568-572. 
  10. Fetal cardiac rhabdomyoma: A sheep or a worlf? Mat-Fet & Neo Med. 2007;20(4):343-348. 
  11. Antibiotic and warfarin interaction in pediatric cardiology patients. Pediatric Cardiology. 2005;(26):1-5. 
  12. Early outcome after glenn shunt and fontan palliation and the impact of operation during viral respiratory season: analysis of a 19 year multi-institutional experience. 2005;(79):613-617. 
  13. Transcatheter occlusion of baffle leaks following atrial switch procedures for transposition of the great vessels (d-tgv). Cath Cardiovasc Interv. 2004;(61):259-263. 
  14. Resolution of right heart enlargement after closure of secundum atrial septal defect by transcatheter technique. J AmColl Cardiol. 2001;(38):1528-1532. 
  15. Echocardiographic prediction of left-to-right shunt with atrial septal defects. J Amer Soc Echo 2000;13:1038-1042. J Amer Soc Echo. 2000;(13):1038-1042. 
  16. Mutations in NKX2.5, a cardiac transcription factor, affect diverse cardiac developmental pathways. J Clin Invest. 1999;(104):1567-1573. 
  17. Diastolic function and tachycardia in hypertensive children. Am J Hypertens. 1999;(12):1009-1014. 
  18. Chromosome abnormalities in congenital heart disease. Am J Med Genet. 1997;(70):292-298. 
  19. Anomalous origin of the right pulmonary artery from the aorta and CATCH 22 syndrome. Ann Thorac Surg. 1995;(60):681-683. 
  20. Deletion within chromosome 22 is common in patients with absent pulmonary valve syndrome. Am J Cardiol. 1995;(76):66-69. 
  21. Comparison of left ventricular mass and function in early versus late repair of coarctation of the aorta. Am J Cardiol. 1994;(73):698-701. 
  22. Repair of coarctation of the aorta in infancy: comparison of surgical and balloon angioplasty. American Heart Journal. 1993;(125):464-468. 
  23. CACP, encoding a secreted proteoglycan is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genetics. 1992;(23):319-322. 
  24. QT prolongation and torsades de pointes after administration of FK506. Transplantation. 1992;(53):929-930. 
Last updated: 08/08/2022
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