Nephrology, Hypertension & Pheresis | Fellowships


The Division has an active fellowship program in Pediatric Nephrology, Hypertension & Pheresis, designed to train sub-specialist pediatricians for academic careers. Clinical responsibilities are concentrated in the first year of the three years of the fellowship. Fellows will manage a wide variety of patients with renal diseases including acute kidney injury, chronic kidney disease, hypertension, renal transplantation, and glomerular and tubular disorders. The fellow will follow their own cohort of patients in the outpatient clinic. They will be exposed to hemodialysis, peritoneal dialysis, continuous renal replacement therapy and apheresis.

Opportunities for both clinical and basic science research in years two and three are available through divisional research and through the outstanding faculty of Washington University in St. Louis School of Medicine. Efforts are made to carefully place each fellow into a thriving research environment appropriate to his/her background and interests to optimize success. Several of our recent fellows are in or have successfully completed: a) dual Med-Peds nephrology fellowship; or b) fast-track residency program into fellowship; or c) a Masters in Clinical and Translational Science research.

Research Training in the Renal Division focuses on several areas of nephrology: renal development, glomerular diseases, genetics, hypertension, chronic kidney diseases (CKD), dialysis and transplantation and their complications. Translational studies of new therapies for renal diseases have emerged from projects led by fellows.

A recent fellow translational project looked at the association of APOL1 high-risk alleles in primary hypertension or glomerular diseases in African-American children. Bench discoveries in the Hruska lab regarding pathophysiology of CKD have included the demonstration that chronic kidney disease directly diminishes skeletal anabolism by inhibiting the function of the BMP and Wnt proteins. Mechanisms of signal transduction through these pathways are current investigational pursuits under the fellowship training program at the present time. In addition, active research programs related to phosphorus, vascular calcification and their cardiovascular complications are available along with new therapeutic approaches to these disorders.

Clinical and translational research in transplantation looks at the impact of complications such as post-transplant infections, malignancies and mineral disorders in chronic rejection. Ongoing studies by fellows or faculty members are investigating autoantibody development or vascular calcification measures. Other recent studies have assessed aortic stiffness in patients with hypertension, beta-2 microglobulin in diagnosis of acute kidney injury.

In addition, division faculty actively participate in multi-center studies through NAPRTCS, PNRC, SCOPE, GLEAN, CKiD, AWARE, AWAKEN, and IROC.

Conference Schedules:

Monday pediatric nephrology conference
Tuesday nephrology research seminar
Wednesday adult pathophysiology conference
Thursday adult clinical case conference
Friday pediatric nephrology conference

Radiology Urology Nephrology (RUN) conference once every six weeks

Application Process

Applications for fellowship training are accepted through ERAS (Electronic Residence Application Service). Applications will be accepted beginning July 1st. For July 2021 start, prospective fellows will be invited to interview after July 1, 2020. Combined Pediatric Subspecialty Match. Three letters of recommendation are required.

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More information on the fellowship program can be obtained by contacting:
Department of Pediatrics
Division of Nephrology, Hypertension & Pheresis

Kathy Kiefer
Fellowship program coordinator

S. Paul Hmiel, M.D. Ph.D.
Fellowship Program Director

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