Gary A. Silverman, M.D., Ph.D.

Developmental BiologySchool of MedicineNewborn Medicine

phone: (314) 454-6148


  • BA, Washington and Jefferson College1978
  • PhD, University of Chicago1982
  • MD, University of Chicago, Pritzer School of Medicine1984


  • Internship, The Children’s Hospital1984 - 1985
  • Junior Assistant Resident, The Children’s Hospital1985 - 1986
  • Senior Assistant Resident, The Children’s Hospital1986 - 1987
  • Fellowship, St. Louis Children’s Hospital/Washington University School of Medicine1987 - 1989
  • Postdoctoral Research Fellow, Washington University School of Medicine1988 - 1991

Licensure and Board Certification

  • National Board of Medical Examiners (Diplomate) 1985
  • MO, Medical License 1987
  • American Board of Pediatrics, Pediatrics 1988
  • American Board of Pediatrics, Neonatal/Perinatal Medicine 1989
  • MA, Medical License 1991
  • American Board of Pediatrics, Neonatal/Perinatal Medicine - recertification 1997
  • American Board of Pediatrics, Neonatal/Perinatal Medicine - recertification 2004
  • PA, Medical License 2004
  • American Board of Pediatrics, Neonatal/Perinatal Medicine - recertification 2013
  • MO, Medical License 2016


  • Phi Sigma, Biology Honorary Society1976
  • Phi Beta Kappa, Washington and Jefferson College1978
  • Solon E. Summerfield Scholarship, Phi Kappa Psi Fraternity1978
  • Birch Scholarship Award, Washington and Jefferson College1978
  • National Science Foundation, Student Originated Studies Program1978
  • National Research Service Award: Medical Scientist Training Program University of Chicago1978
  • The Medical Alumni Prize, University of Chicago1982
  • Individual National Research Service Award, NICHHD1988
  • Leukemia Society Special Fellowship1991
  • FIRST Award, National Institute of Child Health and Human Development1991
  • Lucille P. Markey Trust Child Health Fellowship1992
  • William Randolph Hearst Award1992
  • March of Dimes Birth Defects Foundation Award1993
  • Elsa U. Pardee Foundation Award1994
  • Biology Smokeless Tobacco Research Council Award1994
  • The Stewart Trust of Washington D.C., Alexander and Margaret Stewart Trust Grant, in Support of Promising Ideas in Basic and Applied Cancer2001
  • Inaugural Class Hartwell Individual Biomedical Research Award2006
  • Top Doctors, Pittsburgh Magazine2009
  • Twenty-Five Club Endowed Professorship, University of Pittsburgh School of Medicine2009 - 2016
  • Top Doctors, Pittsburgh Magazine2010
  • Cellome Award, Thermo Scientific2011
  • America’s Top Doctors, Castle Connolly2011
  • Top Doctors, Pittsburgh Magazine2011
  • Distinguished Service Award, Washington & Jefferson College2011
  • America’s Top Doctors, Castle Connolly2012
  • 2014 AAP CME/CPD Award (Continuing Medical Education /Continuing Professional Development)2014
  • Top Doctors, Pittsburgh Magazine2015
  • 2015 Marshall W. Webster Physician Leadership Program, University of Pittsburgh School of Medicine2015
  • 2015 Scholars Day Award, University of Pittsburgh School of Medicine2015
  • The Harriet B. Spoehrer Professorship of Pediatrics, Washington University School of Medicine2016

Recent Publications view all (10)

Publication Co-Authors

  1. Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit. J Biol Chem. 2016;291(27):14012-22. PMCID:PMC4933161  PMID:27189943 
  2. High-Throughput, Liquid-Based Genome-Wide RNAi Screening in C. elegans. Methods Mol Biol. 2016;1470:151-62. PMID:27581291 
  3. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12(1):1-222. PMCID:PMC4835977  PMID:26799652 
  4. Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy. J Biol Chem. 2015;290(50):29742-57. PMCID:PMC4705969  PMID:26494620 
  5. SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin. Biochemistry. 2015;54(45):6756-9. PMCID:PMC4900762  PMID:26497600 
  6. Human SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia. J Histochem Cytochem. 2015;63(11):854-65. PMCID:PMC4812677  PMID:26220980 
  7. The aggregation-prone intracellular serpin SRP-2 fails to transit the ER in Caenorhabditis elegans. Genetics. 2015;200(1):207-19. PMCID:PMC4423363  PMID:25786854 
  8. Deficient and Null Variants of SERPINA1 Are Proteotoxic in a Caenorhabditis elegans Model of α1-Antitrypsin Deficiency. PLoS One. 2015;10(10):e0141542. PMCID:PMC4626213  PMID:26512890 
  9. Worming our way to novel drug discovery with the Caenorhabditis elegans proteostasis network, stress response and insulin-signaling pathways. Expert Opin Drug Discov. 2014;9(9):1021-32. PMID:24998976 
  10. Expanding the C. elegans toolbox into a toolshed. Methods. 2014;68(3):379-80. PMID:25064639 
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