Lori R. Holtz, M.D., M.S.P.H.  holtz_l@kids.wustl.edu

Assistant Professor of Pediatrics, Gastroenterology, Hepatology and Nutrition
Researcher, Pathobiology
Gastroenterology, Hepatology and NutritionPathobiology

phone: (314) 454-6173


  • BS, Tulane University1999
  • MD, The Ohio State University College of Medicine2003
  • MSPH, St. Louis University School of Public Health2014


  • Residency, Vanderbilt Children's Hospital2003 - 2006
  • Fellowship, Washington University2006 - 2009

Licensure and Board Certification

  • American Board of Pediatrics 2006
  • MO, 2008
  • American Board of Pediatrics, Sub-board of Pediatric Gastroenterology 2009


  • National Science Scholar1995
  • Tulane University Partial Academic Scholarship1995 - 1999
  • Funding from the National Science Foundation research experience for undergraduates1998
  • Cum Laude, Tulane University1999
  • NASPGHAN travel grant2008
  • Children's Discovery Institute Faculty Scholar2013 - Pres
  • St. Louis Best Doctors2015 - 2018
  • Washington University Institute for Public Health Scholar2016 - Pres
  • March of Dimes Basil O'Connor Award2017 - 2019
  • Doris Duke Clinical Scientist Development Award2017 - 2020

Recent Publications view all (23)

Publication Co-Authors

  1. Propagation of astrovirus VA1, a neurotropic human astrovirus, in cell culture. J Virol. 2017. PMID:28701405 
  2. Case-Control Assessment of the Roles of Noroviruses, Human Bocaviruses 2, 3, and 4, and Novel Polyomaviruses and Astroviruses in Acute Childhood Diarrhea. J Pediatric Infect Dis Soc. 2017. PMID:28186546 
  3. Statoviruses, A novel taxon of RNA viruses present in the gastrointestinal tracts of diverse mammals. Virology. 2017;504:36-44. PMID:28152382 
  4. Risk Factors Associated with Very Low Birth Weight in a Large Urban Area, Stratified by Adequacy of Prenatal Care. Matern Child Health J. 2016;20(3):623-9. doi:10.1007/s10995-015-1861-4  PMID:26537389 
  5. A diverse group of small circular ssDNA viral genomes in human and non-human primate stools. Virus Evol. 2015;1(1):vev017. PMCID:PMC5014484  PMID:27774288 
  6. Early life dynamics of the human gut virome and bacterial microbiome in infants. Nat Med. 2015. doi:10.1038/nm.3950  PMID:26366711 
  7. Prevalence of classic, MLB-clade and VA-clade Astroviruses in Kenya and The Gambia. Virol J. 2015;12:78. doi:10.1186/s12985-015-0299-z  PMCID:PMC4465002  PMID:25975198 
  8. Geographic variation in the eukaryotic virome of human diarrhea. Virology. 2014;468-470:556-64. doi:10.1016/j.virol.2014.09.012  PMCID:PMC4254309  PMID:25262473 
  9. Seroepidemiology of astrovirus MLB1. Clin Vaccine Immunol. 2014;21(6):908-11. doi:10.1128/CVI.00100-14  PMID:24789796 
  10. Discovery of rosavirus 2, a novel variant of a rodent-associated picornavirus, in children from The Gambia. Virology. 2014;454-455:25-33. doi:10.1016/j.virol.2014.01.018  PMID:24725928 
  11. Comparison of novel MLB-clade, VA-clade and classic human astroviruses highlights constrained evolution of the classic human astrovirus nonstructural genes. Virology. 2013;436(1):8-14. doi:10.1016/j.virol.2012.09.040  PMCID:PMC3545029  PMID:23084422 
  12. Human polyomaviruses in children undergoing transplantation, United States, 2008-2010. Emerg Infect Dis. 2012;18(10):1676-9. doi:10.3201/eid1810.120359  PMCID:PMC3471627  PMID:23017293 
  13. Novel astroviruses in children, Egypt. Emerg Infect Dis. 2011;17(12):2391-3. doi:10.3201/eid1712.110909  PMCID:PMC3311207  PMID:22172277 
  14. Astrovirus MLB2 viremia in febrile child. Emerg Infect Dis. 2011;17(11):2050-2. doi:10.3201/eid1711.110496  PMCID:PMC3310569  PMID:22099095 
  15. Astrovirus MLB1 is not associated with diarrhea in a cohort of Indian children. PLoS One. 2011;6(12):e28647. doi:10.1371/journal.pone.0028647  PMCID:PMC3235140  PMID:22174853 
  16. Serological evidence of human klassevirus infection. Clin Vaccine Immunol. 2010;17(10):1584-8. doi:10.1128/CVI.00152-10  PMCID:PMC2952992  PMID:20739504 
  17. Detection of novel sequences related to african Swine Fever virus in human serum and sewage. J Virol. 2009;83(24):13019-25. doi:10.1128/JVI.00638-09  PMCID:PMC2786824  PMID:19812170 
  18. Human stool contains a previously unrecognized diversity of novel astroviruses. Virol J. 2009;6:161. doi:10.1186/1743-422X-6-161  PMCID:PMC2765957  PMID:19814825 
  19. Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread. Virol J. 2009;6:86. doi:10.1186/1743-422X-6-86  PMCID:PMC2706813  PMID:19552824 
  20. Acute bloody diarrhea: a medical emergency for patients of all ages. Gastroenterology. 2009;136(6):1887-98. doi:10.1053/j.gastro.2009.02.059  PMID:19457417 
  21. Detection of newly described astrovirus MLB1 in stool samples from children. Emerg Infect Dis. 2009;15(3):441-4. doi:10.3201/eid1503.081213  PMCID:PMC2666294  PMID:19239759 
  22. Identification of a novel picornavirus related to cosaviruses in a child with acute diarrhea. Virol J. 2008;5:159. doi:10.1186/1743-422X-5-159  PMCID:PMC2615758  PMID:19102772 
  23. GH mRNA levels are elevated by forskolin but not GH releasing hormone in GHRH receptor-expressing MtT/S somatotroph cell line. Mol Cell Endocrinol. 2001;172(1-2):125-34. PMID:11165046 
Last updated: 02/26/2018
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