Department of Pediatrics

Education

• BA, Highest Honors and Summa Cum Laude, University of North Carolina at Chapel Hill, 2006
• MD, Virginia Commonwealth University/Medical College of Virginia, 2012

Training

• Pediatric Residency, Northwestern University/Ann & Robert H. Lurie Children's Hospital of Chicago, 2012 - 2015
• Pediatric Hematology/Oncology Fellowship, Northwestern/Ann & Robert H. Lurie Children's Hospital of Chicago, 2015 - 2018

Licensure and Board Certification

• MO, License of Physician and Surgeon
• IL, License of Physician and Surgeon
• 2015Pediatrics
• 2019Pediatric Hematology/Oncology

Honors and Awards

• James M. Johnston Scholarship, UNC-Chapel Hill, 2002 - 2006
• Phi Beta Kappa, UNC-Chapel Hill, 2005
• Patrick F. Earey Chancellor’s Award, UNC-Chapel Hill, 2006
• Pediatric Elizabeth Joanne Harbison Memorial Award, VCU School of Medicine, 2012
• Young Investigator Award, Pediatric Bone Marrow Transplant Consortium, 2014
• Alpha Omega Alpha, Northwestern University Feinberg School of Medicine, 2015
• Exemplary Model of Professionalism, Northwestern University/McGaw Medical Center, 2018
• Red Shoes Award for quality, family-centered care, Riley Hospital for Children, 2019

Recent Publications view all (23)

Publication Co-Authors

Nicole Brossier

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Amy Armstrong

1. Dehner CA, Armstrong AE, Yohe M, Shern JF, Hirbe AC. Genetic Characterization, Current Model Systems and Prognostic Stratification in PAX Fusion-Negative vs. PAX Fusion-Positive Rhabdomyosarcoma. Genes (Basel). 2021;12(10). PMCID:PMC8535289  PMID:34680895 
2. Sous D, Armstrong AE, Huang JT, Shah S, Carlberg VM, Coughlin CC. Cutaneous reactions to pediatric cancer treatment: Part I. Conventional chemotherapy. Pediatr Dermatol. 2021;38(1):8-17. PMID:33170534 
3. Fisher MJ, Shih CS, Rhodes SD, Armstrong AE, Wolters PL, Dombi E, Zhang C, Angus SP, Johnson GL, Packer RJ, Allen JC, Ullrich NJ, Goldman S, Gutmann DH, Plotkin SR, Rosser T, Robertson KA, Widemann BC, Smith AE, Bessler WK, He Y, Park SJ, Mund JA, Jiang L, Bijangi-Vishehsaraei K, Robinson CT, Cutter GR, Korf BR, Neurofibromatosis Clinical Trials Consortium., Blakeley JO, Clapp DW. Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial. Nat Med. 2021;27(1):165-173. PMCID:PMC8275010  PMID:33442015 
4. Armstrong AE, Brossier NM, Hirbe AC. Neurofibromatosis type 1-related tumours in paediatrics: an evolving treatment landscape. Lancet Child Adolesc Health. 2020. PMID:32562630 
5. Armstrong AE, Rhodes SD, Smith AE, Chen S, Bessler WK, Ferguson MJ, Jiang L, Li X, Yuan J, Yang X, Yang F-C, Robertson KA, Ingram DA, Clapp DW. Early Administration of Imatinib Mesylate Reduces Plexiform Neurofibroma Tumor Burden with Durable Results after Drug Discontinuation in a Mouse Model of Neurofibromatosis Type 1 Pediatric Blood Cancer. 2020. PMID:32459399 
6. Rhodes SD, He Y, Smith A, Jiang L, Lu Q, Mund J, Li X, Bessler W, Qian S, Dyer W, Sandusky GE, Horvai AE, Armstrong AE, Clapp DW. Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation. Hum Mol Genet. 2019;28(16):2752-2762. PMCID:PMC6687955  PMID:31091306 
7. Rossoff J, Chaudhury S, Soneji M, Patel SJ, Kwon S, Armstrong A, Muller WJ. Noninvasive Diagnosis of Infection Using Plasma Next-Generation Sequencing: A Single-Center Experience Open Forum Infect Dis. 2019. PMID:31375834 
8. Armstrong AE, Rossoff J, Hollemon D, Hong DK, Muller WJ, Chaudhury S. Cell-free DNA next-generation sequencing successfully detects infectious pathogens in pediatric oncology and hematopoietic stem cell transplant patients at risk for invasive fungal disease. Pediatr Blood Cancer. 2019;66(7):e27734. PMID:30941906 
9. Applebaum MA, Barr EK, Karpus J, Nie J, Zhang Z, Armstrong AE, Uppal S, Sukhanova M, Zhang W, Chlenski A, Salwen HR, Wilkinson E, Dobratic M, Grossman R, Godley LA, Stranger BE, He C, Cohn SL. 5-Hydroxymethylcytosine Profiles Are Prognostic of Outcome in Neuroblastoma and Reveal Transcriptional Networks That Correlate With Tumor Phenotype. JCO Precis Oncol. 2019;3. PMCID:PMC6553657  PMID:31179414 
10. Armstrong AE, Walterhouse DO, Leavey PJ, Reichek J, Walz AL. Prolonged response to sorafenib in a patient with refractory metastatic osteosarcoma and a somatic PDGFRA D846V mutation. Pediatr Blood Cancer. 2019;66(1):e27493. PMID:30318721 
11. Armstrong AE, Gadd S, Huff V, Gerhard DS, Dome JS, Perlman EJ. A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study. PLoS One. 2018;13(12):e0208936. PMCID:PMC6292605  PMID:30543698 
12. Dabrowski E, Armstrong AE, Leeth E, Johnson E, Cheng E, Gosiengfiao Y, Finlayson C. Proximal Hypospadias and a Novel WT1 Variant: When Should Genetic Testing Be Considered? Pediatrics. 2018;141(Suppl 5):S491-S495. PMID:29610178 
13. Armstrong AE, Fonstad R, Spellman S, Tullius Z, Chaudhury S. Current Knowledge and Practice of Pediatric Providers in Umbilical Cord Blood Banking. Clin Pediatr (Phila). 2018;57(2):161-167. PMID:28952356 
14. Armstrong AE, Danner-Koptik K, Golden S, Schneiderman J, Kletzel M, Reichek J, Gosiengfiao Y. Late Effects in Pediatric High-risk Neuroblastoma Survivors After Intensive Induction Chemotherapy Followed by Myeloablative Consolidation Chemotherapy and Triple Autologous Stem Cell Transplants. J Pediatr Hematol Oncol. 2018;40(1):31-35. PMID:28538090 
15. Gadd S, Huff V, Walz AL, Ooms AHAG, Armstrong AE, Gerhard DS, Smith MA, Auvil JMG, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Hermida LC, Davidsen T, Gesuwan P, Ma Y, Zong Z, Mungall AJ, Moore RA, Marra MA, Dome JS, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Ross N, Gastier-Foster JM, Arold ST, Perlman EJ. A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor. Nat Genet. 2017;49(10):1487-1494. PMCID:PMC5712232  PMID:28825729 
16. Armstrong AE, Smyth E, Helenowski IB, Tse WT, Duerst RE, Schneiderman J, Kletzel M, Chaudhury S. The Impact of High-resolution HLA-A, HLA-B, HLA-C, and HLA-DRB1 on Transplant-related Outcomes in Single-unit Umbilical Cord Blood Transplantation in Pediatric Patients. J Pediatr Hematol Oncol. 2017;39(1):26-32. PMID:27820121 
17. Armstrong AE, Weese-Mayer DE, Mian A, Maris JM, Batra V, Gosiengfiao Y, Reichek J, Madonna MB, Bush JW, Shore RM, Walterhouse DO. Treatment of neuroblastoma in congenital central hypoventilation syndrome with a PHOX2B polyalanine repeat expansion mutation: New twist on a neurocristopathy syndrome. Pediatr Blood Cancer. 2015;62(11):2007-10. PMID:26011159 
18. Armstrong AE, Dargart J, Reichek J, Walterhouse DO, Matossian D, Cohn RA, Gosiengfiao Y. Irinotecan and temozolomide for treatment of neuroblastoma in a patient with renal failure on hemodialysis. Pediatr Blood Cancer. 2014;61(5):949-50. PMID:24273036 
19. Sharma A, Armstrong AE, Posner MP, Kimball PM, Cotterell AH, King AL, Fisher RA, Godder K. Graft-versus-host disease after solid organ transplantation: a single center experience and review of literature. Ann Transplant. 2012;17(4):133-9. PMID:23274334 
20. Sharma A, Armstrong AE. Giant cell tumor of rib arising anteriorly as a large inframammary mass: a case report and review of the literature. Case Rep Med. 2012;2012:850509. PMCID:PMC3522514  PMID:23251185 
21. Saccoccio FM, Sauer AL, Cui X, Armstrong AE, Habib el-SE, Johnson DC, Ryckman BJ, Klingelhutz AJ, Adler SP, McVoy MA. Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells. Vaccine. 2011;29(15):2705-11. PMCID:PMC3084484  PMID:21310190 
22. Sous D, Armstrong AE, Huang JT, Shah SD, Carlberg VM, Coughlin CC. Cutaneous Reactions to Pediatric Cancer Treatment: Part I: Conventional Chemotherapy Pediatric Dermatology. 
23. Fisher MJ, Shih C-S, Rhodes SD, Armstrong AE, Wolters PL, Dombi E, Zhang C, Angus SP, Johnson GL, Packer RJ, Allen JC, Ullrich NJ, Goldman S, Gutmann DH, Plotkin SR, Rosser T, Robertson KA, Widemann BC, Smith AE, Bessler WK, He Y, Park S-J, Mund JA, Jiang L, Bijangi-Vishehsaraei K, Thomas C, Cutter GR, Korf B, Blakeley JO, Clapp DW. Kinase enrichment proteomics inform mechanism of action and biomarker discovery in a Neurofibromatosis Clinical Trials Consortium phase 2 clinical trial of cabozantinib (XL184) for neurofibromatosis type 1 related plexiform neurofibromas Nature Medicine.