Department of Pediatrics

Clinical Interests

Dr. Coverstone is an Assistant Professor of Pediatrics within the Division of Allergy and Pulmonary Medicine. She graduated from Gonzaga University in Spokane, WA in 2004 with a Bachelor’s of Science in Biology. She went on to receive her medical degree from Saint Louis University School of Medicine and completed her internship and residency in pediatrics at the University of North Carolina in Chapel Hill (2009-2012). After residency she returned to Saint Louis, where she completed her fellowship in Pediatric Pulmonology at Washington University in St Louis and earned her certificate in clinical investigation. Dr. Coverstone joined the faculty in 2015 and is a member of the American Thoracic Society and Arnold P Gold Humanism in Medicine Honor Society. Dr. Coverstone’s research focuses on understanding childhood asthma, particularly severe asthma. She is involved with research efforts through the Severe Asthma Research Program and AsthmaNet. In addition, she is a member of the Cystic Fibrosis (CF) Quality Improvement Team at St Louis Children’s Hospital and the CF Therapeutics Development Network.

Education

• BS, Gonzaga University, 2004
• MD, Saint Louis University School of Medicine, 2009
• MSCI, Washington University School of Medicine in St Louis, 2015

Training

• Pediatric Residency, University of North Carolina Hospitals, 2009 - 2012
• Pediatric Pulmonary Fellowship, Washington University in Saint Louis School of Medicine, 2012 - 2015

Licensure and Board Certification

• 2012 - PresMO, Missouri Board of Healing Arts Medical License
• 2012 - PresAmerican Board of Pediatrics
• 2016 - PresAmerican Board of Pediatrics, Pediatric Pulmonology
• 2020 - PresIL, Medical License

Honors and Awards

• Who's Who Among Students in American Universities and Colleges, Gonzaga University, 2004
• Donald W. Bussman Award, St Louis University School of Medicine, 2009
• Paul J McBryan Award, St Louis University School of Medicine, 2009
• Rodney M. Coe Award for MD with Distinction in Community Service, St Louis University School of Medicine, 2009
• St Louis Pediatric Society Award, 2009
• American Thoracic Society Fellows Track Symposium Award, 2014

Recent Publications view all (25)

Publication Co-Authors

James Kemp, M.D.

Gregory A. Storch, M.D.

Mythili Srinivasan, M.D., Ph.D.

Jeffrey Stokes, M.D.

Andrew J. White, M.D.

Thomas Ferkol, M.D.

Mario Castro

Katherine Rivera-Spoljaric, M.D., MSCI

Avraham Beigelman, M.D.

Dorothy Katherine Grange, M.D.

Sarah Bram M.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Andrea Coverstone, M.D.

1. Srinivasan M, Bacharier LB, Goss CW, Zhou Y, Boomer J, Bram S, Burgdorf D, Burnham CA, Casper T, Castro M, Coverstone A, Haslam M, Kanchongkittiphon W, Kuklinski C, Lian Q, Schechtman K, Storch GA, True K, Wallace MA, Yin-DeClue H, Ahrens E, Wang J, Beigelman A. The azithromycin to prevent wheezing following severe RSV bronchiolitis-II clinical trial: Rationale, study design, methods, and characteristics of study population. Contemp Clin Trials Commun. 2021;22:100798. PMCID:PMC8219746  PMID:34189338 
2. Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips BR, Wenzel SE, Fahy JV, Israel E, Bleecker ER. Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program. Am J Respir Crit Care Med. 2021;203(7):882-892. PMCID:PMC8017570  PMID:33545021 
3. Coverstone AM, Boomer JS, Lew D, Bacharier LB, Castro M, Severe Asthma Research Program (SARP) Investigators.. Type 2 inflammation in the sputum of adolescents with asthma. Ann Allergy Asthma Immunol. 2021;126(3):297-299. PMCID:PMC8062219  PMID:33276117 
4. Coverstone AM, Ferkol TW. Early Diagnosis and Intervention in Cystic Fibrosis: Imagining the Unimaginable. Front Pediatr. 2021;8:608821. PMCID:PMC7830672  PMID:33505947 
5. Phipatanakul W, Mauger DT, Guilbert TW, Bacharier LB, Durrani S, Jackson DJ, Martinez FD, Fitzpatrick AM, Cunningham A, Kunselman S, Wheatley LM, Bauer C, Davis CM, Geng B, Kloepfer KM, Lapin C, Liu AH, Pongracic JA, Teach SJ, Chmiel J, Gaffin JM, Greenhawt M, Gupta MR, Lai PS, Lemanske RF, Morgan WJ, Sheehan WJ, Stokes J, Thorne PS, Oettgen HC, Israel E, PARK Study Team.. Preventing asthma in high risk kids (PARK) with omalizumab: Design, rationale, methods, lessons learned and adaptation. Contemp Clin Trials. 2021;100:106228. PMCID:PMC7887056  PMID:33242697 
6. Brennan S, Marmor I, Schafer C, Ko J, Torres Garcia JA, Rosman IS, Coughlin C, Coverstone A, White AJ. Serum sickness-like reaction following initiation of elexacaftor/tezacaftor/ivacaftor therapy. Pediatr Pulmonol. 2020. PMID:32956574 
7. Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips B, Wenzel SE, Fahy JV, Israel E, Bleecker ER, NHLBI SARP 3 Investigators.. Baseline sputum eosinophil + neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) cohort. J Allergy Clin Immunol. 2020. PMID:32032631 
8. Coverstone AM, Seibold MA, Peters MC. Diagnosis and Management of T2-High Asthma. J Allergy Clin Immunol Pract. 2020;8(2):442-450. PMID:32037108 
9. Coverstone AM, Bacharier LB, Wilson BS, Fitzpatrick AM, Teague WG, Phipatanakul W, Wenzel SE, Gaston BM, Bleecker ER, Moore WC, Ramratnam S, Jarjour NN, Ly NP, Fahy JV, Mauger DT, Schechtman KB, Yin-DeClue H, Boomer JS, Castro M. Clinical significance of the bronchodilator response in children with severe asthma. Pediatr Pulmonol. 2019. PMID:31424170 
10. Coverstone AM, Wang L, Sumino K. Beyond Respiratory Syncytial Virus and Rhinovirus in the Pathogenesis and Exacerbation of Asthma: The Role of Metapneumovirus, Bocavirus and Influenza Virus. Immunol Allergy Clin North Am. 2019;39(3):391-401. PMID:31284928 
11. Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Fajt ML, Wenzel SE, Israel E, Levy BD, Fahy JV. Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma. Am J Respir Crit Care Med. 2019;199(9):1076-1085. PMCID:PMC6515873  PMID:30888839 
12. Schaefer N, Li X, Seibold MA, Jarjour NN, Denlinger LC, Castro M, Coverstone AM, Teague WG, Boomer J, Bleecker ER, Meyers DA, Moore WC, Hawkins GA, Fahy J, Phillips BR, Mauger DT, Dakhama A, Gellatly S, Pavelka N, Berman R, Di YP, Wenzel SE, Chu HW. The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium. JCI Insight. 2019;4(8). PMCID:PMC6538329  PMID:30996135 
13. Coverstone AM, Bacharier LB. Airway Inflammatory Patterns in Severe Childhood Asthma-How Might This Change General Practice? J Allergy Clin Immunol Pract. 2019;7(6):1813-1814. PMID:31279464 
14. Coverstone AM, Wilson B, Burgdorf D, Schechtman KB, Storch GA, Holtzman MJ, Castro M, Bacharier LB, Sumino K. Recurrent wheezing in children following human metapneumovirus infection. J Allergy Clin Immunol. 2018;142(1):297-301.e2. PMID:29481834 
15. DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague W.. Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. BMC Pulm Med.. 2018;18(1):58. doi:10.1186/s12890-018-0612-x.  PMID:29631584 
16. MC Peters, S Kerr, EM Dunican, PG Woodruff, ML Fajt, BD Levy, E Israel, BR Phillips, DT Mauger, SA Comhair, SC Erzurum, MW Johansson, NN Jarjour, AM Coverstone, M Castro, AT Hastie, ER Bleecker, SE Wenzel and JV Fahy . Refractory Airway Type-2 Inflammation in a Large Subgroup of Asthmatics treated with Inhaled Corticosteroids JACI. 2018. doi:10.1016/j.jaci.2017.12.1009  PMID:29524537 
17. Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN. Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract. 2018;6(2):545-554.e4. PMCID:PMC5832534  PMID:28866107 
18. Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD, National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators. ALX receptor ligands define a biochemical endotype for severe asthma. JCI Insight. 2017;2(14). doi:10.1172/jci.insight.93534  PMCID:PMC5518567  PMID:28724795 
19. Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD, National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.. Natural killer cell-mediated inflammation resolution is disabled in severe asthma. Sci Immunol. 2017;2(9). PMCID:PMC5561743  PMID:28783702 
20. Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN, National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators. Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med. 2017;195(3):302-313. PMCID:PMC5328178  PMID:27556234 
21. Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, Wenzel SE, Woodruff PG, Bleecker ER, Fahy JV. Plasma IL6 levels, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts Lancet Respir Med 2016. 2016;4(7):574-584. doi:10.1016/S2213-2600(16)30048-0  PMID:27283230 
22. Boyer D, Nevin M, Thomson CC, Sanders DB, Alexiou S, Goldfarb SB, Nicholas JL, Thacker PG, Coverstone AM, Faro A, Cheng G, Majid A, Moore PE. ATS Core Curriculum 2015: Part III. Pediatric Pulmonary Medicine. Ann Am Thorac Soc. 2015;12(11):1688-96. doi:10.1513/AnnalsATS.201506-322CME  PMID:26540419 
23. Coverstone A, Bacharier LB, Fitzpatrick AM. Severe asthma in school-age children: evaluation and phenotypic advances. Curr Allergy Asthma Rep. 2015;15(5):521. doi:10.1007/s11882-015-0521-5  PMID:26134431 
24. Coverstone AM, Bird M, Sicard M, Tao Y, Grange DK, Cleveland C, Molter D, Kemp JS. Overnight pulse oximetry for evaluation of sleep apnea among children with trisomy 21. J Clin Sleep Med. 2014;10(12):1309-15. doi:10.5664/jcsm.4286  PMCID:PMC4237524  PMID:25325597 
25. Joyner BL, Jones SW, Cairns BA, Harris BD, Coverstone AM, Abode KA, Ortiz-Pujols SM, Kocis KC, Noah TL. DNA and inflammatory mediators in bronchoalveolar lavage fluid from children with acute inhalational injuries. J Burn Care Res. 2013;34(3):326-33. doi:10.1097/BCR.0b013e31825d5126  PMCID:PMC3567221  PMID:23128126