Department of Pediatrics

Education

• BS, cum laude, Furman University, 2002
• MD, University of Virginia, 2006
• MSCI, Washington University in St. Louis, 2016

Training

• Pediatric Residency, Washington University in St. Louis, 2006 - 2008
• Pediatric Neurology Residency, Washington University in St. Louis, 2008 - 2011
• Pediatric Critical Care Fellowship, Washington University in St. Louis, 2011 - 2014

Licensure and Board Certification

• 2011 - PresMO, Missouri Medical License
• 2011 - PresAmerican Board of Psychiatry and Neurology with Child Specialization
• 2012 - PresAmerican Board of Pediatrics: General Pediatrics
• 2013 - PresPALS Instructor
• 2014 - PresAmerican Board of Pediatrics: Pediatric Critical Care Medicine
• 2021 - PresIL, Licensed Physician and Surgeon

Honors and Awards

• Steven M Rothman Award (Outstanding Teaching by Pediatric Neurology Resident), 2010
• Child Neurology Foundation PERF Scientific Award, 2015
• Neurology Clerkship Student Teaching Award Honor Roll, 2020

Recent Publications view all (46)

Publication Co-Authors

Fields, Melanie

Mary E. Hartman, M.D., M.P.H.

Monica Hulbert, M.D.

Allison King, M.D., M.P.H., Ph.D.

Ahmed, Said, M.D., Ph.D.

Stuart Friess, M.D.

Dorothy Katherine Grange, M.D.

John C. Lin, M.D.

Avihu Z. Gazit, M.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Kristin Guilliams, MD MSCI

1. Roessler HI, van der Heuvel LM, Shields K, Guilliams KP, Knoers NVAM, van Haaften G, Grange DK, van Haelst MM. Behavioral and cognitive functioning in individuals with Cantú syndrome. Am J Med Genet A. 2021;185(8):2434-2444. PMID:34056838 
2. Wang Y, Fellah S, Fields ME, Guilliams KP, Binkley MM, Eldeniz C, Shimony JS, Reis M, Vo KD, Chen Y, Lee JM, An H, Ford AL. Cerebral Oxygen Metabolic Stress, Microstructural Injury, and Infarction in Adults With Sickle Cell Disease. Neurology. 2021. PMID:34172536 
3. Eldeniz C, Binkley MM, Fields M, Guilliams K, Ragan DK, Chen Y, Lee JM, Ford AL, An H. Bulk volume susceptibility difference between deoxyhemoglobin and oxyhemoglobin for HbA and HbS: A comparative study. Magn Reson Med. 2021;85(6):3383-3393. PMCID:PMC7945010  PMID:33475200 
4. Huguenard AL, Guerriero RM, Tomko SR, Limbrick DD, Zipfel GJ, Guilliams KP, Strahle JM. Immediate Postoperative Electroencephalography Monitoring in Pediatric Moyamoya Disease and Syndrome. Pediatr Neurol. 2021;118:40-45. PMID:33773289 
5. Lauzier DC, Galardi MM, Guilliams KP, Goyal MS, Amlie-Lefond C, Hallam DK, Kansagra AP. Pediatric Thrombectomy: Design and Workflow Lessons From Two Experienced Centers. Stroke. 2021;52(4):1511-1519. PMCID:PMC7987698  PMID:33691502 
6. Guerriero RM, Morrissey MJ, Loe M, Reznikov J, Binkley MM, Ganniger A, Griffith JL, Khanmohammadi S, Rudock R, Guilliams KP, Ching S, Tomko SR. Macroperiodic Oscillations Are Associated With Seizures Following Acquired Brain Injury in Young Children. J Clin Neurophysiol. 2021. PMID:33587388 
7. Malaiyandi D, James E, Peglar L, Karim N, Henkel N, Guilliams K. Neurocritical Care of the Pregnant Patient. Curr Treat Options Neurol. 2021;23(7):22. PMCID:PMC8214980  PMID:34177249 
8. Bauer Huang SL, Said AS, Smyser CD, Lin JC, Guilliams KP, Guerriero RM. Seizures Are Associated With Brain Injury in Infants Undergoing Extracorporeal Membrane Oxygenation. J Child Neurol. 2020;883073820966917. PMID:33112194 
9. Fields ME, Mirro AE, Guilliams KP, Binkley MM, Gil Diaz L, Tan J, Fellah S, Eldeniz C, Chen Y, Ford AL, Shimony JS, King AA, An H, Smyser CD, Lee JM. Functional Connectivity Decreases with Metabolic Stress in Sickle Cell Disease. Ann Neurol. 2020. PMID:32869335 
10. Guerriero RM, Guilliams KP. Pediatric Neurocritical Care: From Field to Follow-Up. Pediatr Neurol. 2020;108:1-2. PMCID:PMC7307635  PMID:31902549 
11. Said AS, Guilliams KP, Bembea MM. Neurological Monitoring and Complications of Pediatric Extracorporeal Membrane Oxygenation Support. Pediatr Neurol. 2020;108:31-39. PMID:32299748 
12. Press CA, Kirschen M, LaRovere K, Risen S, Guilliams KP, Chung M, Griffith J, Erklauer J, Peariso K, Ducharme-Crevier L, Shah SS, Hall M, Wainwright MS. Variation in Treatment and Outcomes of Children With Acute Disseminated Encephalomyelitis. Hosp Pediatr. 2020;10(2):159-165. PMID:31996356 
13. Galardi MM, Strahle JM, Skidmore A, Kansagra AP, Guilliams KP. Cerebrovascular Complications of Pediatric Blunt Trauma. Pediatr Neurol. 2020. PMID:32111560 
14. Poppert Cordts KM, Hall TA, Hartman ME, Luther M, Wagner A, Piantino J, Guilliams KP, Guerriero RM, Jara J, Williams CN. Sleep Measure Validation in a Pediatric Neurocritical Care Acquired Brain Injury Population. Neurocrit Care. 2019. PMID:31797275 
15. Mineyko A, Kirton A, Billinghurst L, Tatishvili NN, Wintermark M, deVeber G, Fox C, SIPS Investigators.. Seizures and Outcome One Year After Neonatal and Childhood Cerebral Sinovenous Thrombosis. Pediatr Neurol. 2019. PMID:31882182 
16. Hood AM, King AA, Fields ME, Ford AL, Guilliams KP, Hulbert ML, Lee JM, White DA. Higher executive abilities following a blood transfusion in children and young adults with sickle cell disease. Pediatr Blood Cancer. 2019;66(10):e27899. doi:10.1002/pbc.27899  PMCID:PMC6707832  PMID:31267645 
17. Lehman LL, DeVeber G, Pergami P, Guilliams KP, Chung M, Felling R, Dowling MM, Rivkin MJ. Characteristics and Outcome in Children With Craniectomy Following Acute Ischemic Stroke in the International Pediatric Stroke Study. J Child Neurol. 2019;34(12):765-769. PMID:31282248 
18. Williams CN, Hartman ME, Guilliams KP, Guerriero RM, Piantino JA, Bosworth CC, Leonard SS, Bradbury K, Wagner A, Hall TA. Postintensive Care Syndrome in Pediatric Critical Care Survivors: Therapeutic Options to Improve Outcomes After Acquired Brain Injury. Curr Treat Options Neurol. 2019;21(10):49. PMID:31559490 
19. Williams CN, Hartman ME, McEvoy CT, Hall TA, Lim MM, Shea SA, Luther M, Guilliams KP, Guerriero RM, Bosworth CC, Piantino JA. Sleep-Wake Disturbances After Acquired Brain Injury in Children Surviving Critical Care. Pediatr Neurol. 2019. PMID:31735567 
20. Chung MG, Guilliams KP, Wilson JL, Beslow LA, Dowling MM, Friedman NR, Hassanein SMA, Ichord R, Jordan LC, Mackay MT, Rafay MF, Rivkin M, Torres M, Zafeiriou D, deVeber G, Fox CK, International Pediatric Stroke Study Investigators.. Arterial Ischemic Stroke Secondary to Cardiac Disease in Neonates and Children. Pediatr Neurol. 2019. PMID:31371125 
21. Christensen JR, Slomine BS, Silverstein FS, Page K, Holubkov R, Dean JM, Moler FW, Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators.. Cardiac Arrest Outcomes in Children With Preexisting Neurobehavioral Impairment. Pediatr Crit Care Med. 2019;20(6):510-517. PMCID:PMC6548585  PMID:30807545 
22. Fields ME^, Guilliams KP^, Ragan D, Binkley MM, Mirro A, Fellah S, Hulbert ML, Blinder M, Eldeniz C, Vo K, Shimony JS, Chen Y, McKinstry RC, An H, Lee JM, Ford AL. Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia. Blood. 2019;133(22):2436-2444. PMCID:PMC6543515  PMID:30858231 
23. Guilliams KP, Kirkham FJ, Holzhauer S, Pavlakis S, Philbrook B, Amlie-Lefond C, Noetzel MJ, Dlamini N, Sharma M, Carpenter JL, Fox CK, Torres M, Ichord RN, Jordan LC, Dowling MM. Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Stroke. 2019;50(5):1089-1094. PMCID:PMC6481313  PMID:31009343 
24. Guilliams KP, Fields ME, Dowling MM. Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease. Stroke. 2019;50(2):266-273. PMCID:PMC6385587  PMID:30661504 
25. Dodd JN, Hall TA, Guilliams K, Guerriero RM, Wagner A, Malone S, Williams CN, Hartman ME, Piantino J. Optimizing Neurocritical Care Follow-Up Through the Integration of Neuropsychology. Pediatr Neurol. 2018;89:58-62. PMID:30442440 
26. Ford AL, Ragan DK, Fellah S, Binkley MM, Fields ME, Guilliams KP, An H, Jordan LC, McKinstry RC, Lee JM, DeBaun MR. Silent infarcts in sickle cell anemia occur in the borderzone region and are associated with low cerebral blood flow. Blood. 2018. PMID:30061156 
27. Ichord R, Silverstein FS, Slomine BS, Telford R, Christensen J, Holubkov R, Dean JM, Moler FW, THAPCA Trial Group.. Neurologic outcomes in pediatric cardiac arrest survivors enrolled in the THAPCA trials. Neurology. 2018;91(2):e123-e131. PMCID:PMC6053110  PMID:29884735 
28. Fields ME^, Guilliams KP^, Ragan DK, Binkley MM, Eldeniz C, Chen Y, Hulbert ML, McKinstry RC, Shimony JS, Vo KD, Doctor A, An H, Ford AL, Lee JM. Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease. Neurology. 2018;90(13):e1134-e1142. PMCID:PMC5880632  PMID:29500287 
29. Guilliams KP^, Fields ME^, Ragan DK, Eldeniz C, Binkley MM, Chen Y, Comiskey LS, Doctor A, Hulbert ML, Shimony JS, Vo KD, McKinstry RC, An H, Lee JM, Ford AL. Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia. Blood. 2018;131(9):1012-1021. PMCID:PMC5833262  PMID:29255068 
30. Dlamini N, Wintermark M, Fullerton H, Strother S, Lee W, Bjornson B, Guilliams KP, Miller S, Kirton A, Filippi CG, Linds A, Askalan R, deVeber G. Harnessing Neuroimaging Capability in Pediatric Stroke: Proceedings of the Stroke Imaging Laboratory for Children Workshop. Pediatr Neurol. 2017;69:3-10. PMID:28259513 
31. Guilliams KP, Fields ME, Ragan DK, Chen Y, Eldeniz C, Hulbert ML, Binkley MM, Rhodes JN, Shimony JS, McKinstry RC, Vo KD, An H, Lee JM, Ford AL. Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy. Pediatr Neurol. 2017;69:49-57. PMCID:PMC5365370  PMID:28159432 
32. Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM, THAPCA Trial Investigators.. Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children. N Engl J Med. 2017;376(4):318-329. PMCID:PMC5310766  PMID:28118559 
33. Fox CK, Mackay MT, Dowling MM, Pergami P, Titomanlio L, Deveber G, SIPS Investigators.. Prolonged or recurrent acute seizures after pediatric arterial ischemic stroke are associated with increasing epilepsy risk. Dev Med Child Neurol. 2017;59(1):38-44. PMID:27422813 
34. Meert KL, Telford R, Holubkov R, Slomine BS, Christensen JR, Dean JM, Moler FW, Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators.. Pediatric Out-of-Hospital Cardiac Arrest Characteristics and Their Association With Survival and Neurobehavioral Outcome. Pediatr Crit Care Med. 2016;17(12):e543-e550. PMCID:PMC5138073  PMID:27679965 
35. Silverstein FS, Slomine BS, Christensen J, Holubkov R, Page K, Dean JM, Moler FW, Therapeutic Hypothermia to Improve Survival After Cardiac Arrest Trial Group.. Functional Outcome Trajectories After Out-of-Hospital Pediatric Cardiac Arrest. Crit Care Med. 2016;44(12):e1165-e1174. PMCID:PMC5129173  PMID:27509385 
36. Hall EM, Leonard J, Smith JL, Guilliams KP, Binkley M, Fallon RJ, Hulbert ML. Reduction in Overt and Silent Stroke Recurrence Rate Following Cerebral Revascularization Surgery in Children with Sickle Cell Disease and Severe Cerebral Vasculopathy. Pediatr Blood Cancer. 2016;63(8):1431-7. PMCID:PMC5443666  PMID:27106860 
37. Moler FW, Hutchison JS, Nadkarni VM, Silverstein FS, Meert KL, Holubkov R, Page K, Slomine BS, Christensen JR, Dean JM, Therapeutic Hypothermia After Pediatric Cardiac Arrest Out-of-Hospital Trial Investigators.. Targeted Temperature Management After Pediatric Cardiac Arrest Due To Drowning: Outcomes and Complications. Pediatr Crit Care Med. 2016;17(8):712-20. PMCID:PMC5123789  PMID:27362855 
38. Guilliams K, Wainwright MS. Pathophysiology and Management of Moderate and Severe Traumatic Brain Injury in Children. J Child Neurol. 2016;31(1):35-45. PMID:25512361 
39. Gross H, Guilliams KP, Sung G. Emergency Neurological Life Support: Acute Ischemic Stroke. Neurocrit Care. 2015;23 Suppl 2:S94-102. PMID:26438453 
40. Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Clark AE, Browning B, Pemberton VL, Page K, Shankaran S, Hutchison JS, Newth CJ, Bennett KS, Berger JT, Topjian A, Pineda JA, Koch JD, Schleien CL, Dalton HJ, Ofori-Amanfo G, Goodman DM, Fink EL, McQuillen P, Zimmerman JJ, Thomas NJ, van der Jagt EW, Porter MB, Meyer MT, Harrison R, Pham N, Schwarz AJ, Nowak JE, Alten J, Wheeler DS, Bhalala US, Lidsky K, Lloyd E, Mathur M, Shah S, Wu T, Theodorou AA, Sanders RC Jr, Dean JM, THAPCA Trial Investigators.. Therapeutic hypothermia after out-of-hospital cardiac arrest in children. N Engl J Med. 2015;372(20):1898-908. PMCID:PMC4470472  PMID:25913022 
41. Guilliams KP, Fields ME, Hulbert ML. Higher-than-expected prevalence of silent cerebral infarcts in children with hemoglobin SC disease. Blood. 2015;125(2):416-7. PMID:25573975 
42. Sinclair AJ, Fox CK, Ichord RN, Almond CS, Bernard TJ, Beslow LA, Chan AK, Cheung M, deVeber G, Dowling MM, Friedman N, Giglia TM, Guilliams KP, Humpl T, Licht DJ, Mackay MT, Jordan LC. Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium. Pediatr Neurol. 2015;52(1):5-15. PMCID:PMC4936915  PMID:25532775 
43. Guilliams K, Rosen M, Buttram S, Zempel J, Pineda J, Miller B, Shoykhet M. Hypothermia for pediatric refractory status epilepticus. Epilepsia. 2013;54(9):1586-94. PMCID:PMC3975144  PMID:23906244 
44. Sejvar JJ, Kakooza AM, Foltz JL, Makumbi I, Atai-Omoruto AD, Malimbo M, Ndyomugyenyi R, Alexander LN, Abang B, Downing RG, Ehrenberg A, Guilliams K, Helmers S, Melstrom P, Olara D, Perlman S, Ratto J, Trevathan E, Winkler AS, Dowell SF, Lwamafa D. Clinical, neurological, and electrophysiological features of nodding syndrome in Kitgum, Uganda: an observational case series. Lancet Neurol. 2013;12(2):166-74. PMID:23305742 
45. Winchester DE, Guilliams K. A purpuric rash and mononeuritis multiplex. Am Fam Physician. 2008;77(4):501-2. PMID:18326170 
46. Guilliams KP^, Gupta N^, Srinivasan S, Binkley MM, Ying C, Couture L, Gross J, Wallace A, McKinstry RC, Vo K, Lee JM, An H, Goyal MS. Magnetic resonance imaging differences in the circle of Willis between healthy children and adults AJNR.