Carmen Halabi, M.D., Ph.D.  halabi_c@kids.wustl.edu

Instructor in Pediatrics, Nephrology
Nephrology

phone: (314) 286-1574

Clinical Interests

My clinical interests include diagnosis and management of congenital anomalies of the kidney and urinary tract, chronic kidney disease, hypertension, kidney stones, urinary tract infections, glomerular diseases including nephrotic and nephritic syndromes, and electrolyte disorders. In the acute setting, as part of the dialysis and pheresis team, we provide all modalities of renal replacement therapies and therapeutic plasma exchange.

Education

  • B.S., Honors and High Distinction, The University of Iowa2001
  • M.D., The University of Iowa Carver College of Medicine2009
  • Ph.D., The University of Iowa2009

Training

  • Resident in Pediatrics, Saint Louis Children's Hospital2009 - 2011
  • Fellow in Pediatric Nephrology, Washington University School of Medicine2011 - 2015

Licensure and Board Certification

  • MO, State Board of Registration for the Healing Arts - Physician and Surgeon2012
  • American Board of Pediatrics/General Pediatrics2012
  • IL, Department of Financial and Professional Regulation - Licensed Physician and Surgeon2015
  • The American Board of Pediatrics/Pediatric Nephrology2016

Honors

  • Predoctoral Training Program in Genetics, National Institutes of Health, 5T32GM008629, PI: Jeffrey Murray, M.D.2005 - 2007
  • Caroline tum Suden/Frances A. Hellebrandt Professional Opportunity Award, American Physiological Society2007
  • Research Day Award for Best Graduate Student Basic Science Poster, Department of Internal Medicine, The University of Iowa Carver College of Medicine2007
  • Research Week Poster Award, THe University of Iowa Carver College of Medicine2007
  • Merck New Investigator Award, American Heart Association - Council on High Blood Pressure2007
  • Best Poster Presentation Award, The University of Iowa Genetics Ph.D. Program2007
  • Dean's Distinguished Dissertation Award, The University of Iowa2010
  • Postdoctoral Developmental Cardiology and Pulmonary Training Program, National Institutes of Health, 5T32HL007873, PI: Robert Mecham, Ph.D.2012 - 2014
  • Trainee Research Award in Pediatric Nephrology, American Society of Pediatric Nephrology2014
  • Physician Scientist Training Program, National Institutes of Health, 2T32HD043010, PI: Alan Schwartz, Ph.D., M.D.2014 - 2015
  • Pediatric Physician-Scientist Training Program Fellowship Support, Mallinckrodt Foundation2014 - 2015
  • Travel Award, American Society for Matrix Biology2014
  • "Teresa Vietti Fellow" Award, Department of Pediatrics, Washington University School of Medicine2015
  • Scholar of the Child Health Research Center at Washington University School of Medicine, National Institutes of Health, K12-HD076224, PI: Alan Schwartz, Ph.D., M.D.2015 - Pres

Recent Publications view all (12)


Publication Co-Authors

  1. Lee VS, Halabi CM, Hoffman EP, Carmichael N, Leshchiner I, Lian CG, Bierhals AJ, Vuzman D, Brigham Genomic Medicine, Mecham RP, Frank NY, Stitziel NO. Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans. Proc Natl Acad Sci U S A. 2016;113(31):8759-64. PMID:27432961  
  2. Halabi CM, Broekelmann TJ, Knutsen RH, Ye L, Mecham RP, Kozel BA. Chronic antihypertensive treatment improves pulse pressure but not large artery mechanics in a mouse model of congenital vascular stiffness. Am J Physiol Heart Circ Physiol. 2015;309(5):H1008-16. doi:10.1152/ajpheart.00288.2015  PMID:26232234  
  3. Igoucheva O, Alexeev V, Halabi CM, Adams SM, Stoilov I, Sasaki T, Arita M, Donahue A, Mecham RP, Birk DE, Chu ML. Fibulin-4 E57K Knock-in Mice Recapitulate Cutaneous, Vascular and Skeletal Defects of Recessive Cutis Laxa 1B with both Elastic Fiber and Collagen Fibril Abnormalities. J Biol Chem. 2015;290(35):21443-59. doi:10.1074/jbc.M115.640425  PMID:26178373  
  4. Davis TK, Halabi CM, Siefken P, Karmarkar S, Leonard J. Aggressive blood pressure control for chronic kidney disease unmasks moyamoya! Clin Kidney J. 2013;6(5):495-9. doi:10.1093/ckj/sft090  PMCID:PMC4438405  PMID:26064513  
  5. Keen HL, Halabi CM, Beyer AM, de Lange WJ, Liu X, Maeda N, Faraci FM, Casavant TL, Sigmund CD. Bioinformatic analysis of gene sets regulated by ligand-activated and dominant-negative peroxisome proliferator-activated receptor gamma in mouse aorta. Arterioscler Thromb Vasc Biol. 2010;30(3):518-25. doi:10.1161/ATVBAHA.109.200733  PMCID:PMC2850258  PMID:20018933  
  6. Feng Y, Xia H, Cai Y, Halabi CM, Becker LK, Santos RA, Speth RC, Sigmund CD, Lazartigues E. Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension. Circ Res. 2010;106(2):373-82. doi:10.1161/CIRCRESAHA.109.208645  PMCID:PMC2818798  PMID:19926873  
  7. de Lange WJ, Halabi CM, Beyer AM, Sigmund CD. Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles. Physiol Genomics. 2008;35(1):1-4. doi:10.1152/physiolgenomics.90284.2008  PMCID:PMC2574738  PMID:18612081  
  8. Beyer AM, de Lange WJ, Halabi CM, Modrick ML, Keen HL, Faraci FM, Sigmund CD. Endothelium-specific interference with peroxisome proliferator activated receptor gamma causes cerebral vascular dysfunction in response to a high-fat diet. Circ Res. 2008;103(6):654-61. doi:10.1161/CIRCRESAHA.108.176339  PMCID:PMC2583077  PMID:18676352  
  9. Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, de Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM. Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension. 2008;51(4):867-71. doi:10.1161/HYPERTENSIONAHA.107.103648  PMCID:PMC2408877  PMID:18285614  
  10. Halabi CM, Beyer AM, de Lange WJ, Keen HL, Baumbach GL, Faraci FM, Sigmund CD. Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension. Cell Metab. 2008;7(3):215-26. doi:10.1016/j.cmet.2007.12.008  PMCID:PMC2275166  PMID:18316027  
  11. McCray PB Jr, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S. Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. J Virol. 2007;81(2):813-21. doi:10.1128/JVI.02012-06  PMCID:PMC1797474  PMID:17079315  
  12. Halabi CM, Sigmund CD. Peroxisome proliferator-activated receptor-gamma and its agonists in hypertension and atherosclerosis : mechanisms and clinical implications. Am J Cardiovasc Drugs. 2005;5(6):389-98. PMID:16259527  
Wash U School of Medicine
Children's Hospital St. Louis
Children's Discovery Institute
© 2017 by Washington University in St. Louis
One Brookings Drive, St. Louis, MO 63130