Monica Hulbert, M.D.

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Assistant Professor of Pediatrics, Hematology and Oncology
Hematology and Oncology

phone: (314) 454-6018

Clinical Interests

As the director of the Sickle Cell Disease Program at St. Louis Children's Hospital, my goal is to ensure that children with sickle cell disease (SCD) receive optimal medical care, including both management of symptoms of SCD as well as treatments that lessen the severity of the disease. The Sickle Cell Disease Team includes physicians, nurses, nurse practitioners, social work, psychology, and other professionals who contribute to the inpatient and outpatient care of children and young adults with SCD.


  • BS, Indiana University1996
  • MD, Washington University School of Medicine2000


  • Residency in Pediatrics, St. Louis Children's Hospital2000 - 2003
  • Fellowship in Pediatric Hematology/Oncology, Washington University School of Medicine2003 - 2006

Licensure and Board Certification

  • IN, Medical Licensing Board, 2006 - 2013
  • American Board of Pediatrics, 2006 - 2016
  • American Board of Pediatrics, Subboard of Pediatric Hematology-Oncology, 2009 - 2023
  • MO, Board of Registration for the Healing Arts, 2011 - Pres


  • Best Doctors in St. Louis2015 - Pres

Recent Publications view all (22)

  1. Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease. Neurology. 2018;90(13):e1134-e1142. PMCID:PMC5880632  PMID:29500287 
  2. Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia. Blood. 2017;131(9):1012-1021. PMID:29255068 
  3. Determining the longitudinal validity and meaningful differences in HRQL of the PedsQL™ Sickle Cell Disease Module. Health Qual Life Outcomes. 2017;15(1):124. PMCID:PMC5468970  PMID:28606098 
  4. Unrelated Umbilical Cord Blood Transplantation for Sickle Cell Disease Following Reduced Intensity Conditioning: Results of a Phase I Trial. Biol Blood Marrow Transplant. 2017;23(9):1587-1592. PMID:28578010 
  5. Increased complications of chronic erythrocytapheresis compared with manual exchange transfusions in children and adolescents with sickle cell disease. Pediatr Blood Cancer. 2017;64:e26635. PMID:28544309 
  6. Red blood cell transfusions during sickle cell anemia vaso-occlusive crises: a report from the magnesium in crisis (MAGiC) study. Transfusion. 2017;57(8):1891-1897. PMID:28500682 
  7. Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy. Pediatr Neurol. 2017;69:49-57. PMCID:PMC5365370  PMID:28159432 
  8. Reduction in Overt and Silent Stroke Recurrence Rate Following Cerebral Revascularization Surgery in Children with Sickle Cell Disease and Severe Cerebral Vasculopathy. Pediatr Blood Cancer. 2016;63(8):1431-7. PMID:27106860 
  9. A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children. Blood. 2015;126(14):1651-1657. doi:10.1182/blood-2015-05-647107  PMID:26232172 
  10. Red blood cell storage duration is not associated with clinical outcomes for acute chest syndrome in children with sickle cell disease. Transfusion. 2015;55(11):2714-2721. doi:10.1111/trf.13176  PMID:26033266 
  11. Aggressive congenital juvenile myelomonocytic leukemia associated with somatic KRAS p.G13D mutation and concurrent germline IGF1R duplication. Leuk Lymphoma. 2015;56(4):1175-8. doi:10.3109/10428194.2014.953152  PMID:25110823 
  12. Health-related quality of life in children with sickle cell anemia: impact of blood transfusion therapy. Am J Hematol. 2015;90(2):139-43. doi:10.1002/ajh.23877  PMCID:PMC4304929  PMID:25345798 
  13. Higher-than-expected prevalence of silent cerebral infarcts in children with hemoglobin SC disease. Blood. 2015;125(2):416-7. doi:10.1182/blood-2014-10-605964  PMID:25573975 
  14. Cerebral vasculopathy in children with sickle cell anemia. Blood Cells Mol Dis. 2015;54(1):17-25. doi:10.1016/j.bcmd.2014.08.007  PMID:25294561 
  15. Clinical course of postthrombotic syndrome in children with history of venous thromboembolism. Blood Coagul Fibrinolysis. 2012;23(1):39-44. doi:10.1097/MBC.0b013e32834bdb1c  PMID:22089938 
  16. Fluorosis because of prolonged voriconazole therapy in a teenager with acute myelogenous leukemia. J Clin Oncol. 2011;29(32):e779-82. doi:10.1200/JCO.2011.35.9604  PMID:21969513 
  17. Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Blood. 2011;117(3):772-9. doi:10.1182/blood-2010-01-261123  PMCID:PMC3035071  PMID:20940417 
  18. Severe hypertriglyceridemia in an infant with red cell pyruvate kinase deficiency. Indian Pediatr. 2007;44(4):303-5. PMID:17468529 
  19. Primary hemorrhagic stroke in children with sickle cell disease is associated with recent transfusion and use of corticosteroids. Pediatrics. 2006;118(5):1916-24. doi:10.1542/peds.2006-1241  PMID:17079562 
  20. Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: a retrospective cohort study of 137 children with sickle cell anemia. J Pediatr. 2006;149(5):710-2. doi:10.1016/j.jpeds.2006.06.037  PMID:17095350 
  21. Pathology quiz case 1. Cervical neuroblastoma (NB). Arch Otolaryngol Head Neck Surg. 2005;131(2):172, 174. doi:10.1001/archotol.131.2.172  PMID:15723954 
  22. Neutropenic enterocolitis as a presenting complication of acute lymphoblastic leukemia: an unusual case marked by delayed perforation of the descending colon. J Pediatr Surg. 2004;39(7):e18-20. PMID:15213940 
Last updated: 08/30/2018
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