Monica Hulbert, M.D.

Assistant Professor of Pediatrics, Hematology and Oncology
Hematology and Oncology

phone: (314) 454-6018

Clinical Interests

As the director of the Sickle Cell Disease Program at St. Louis Children's Hospital, my goal is to ensure that children with sickle cell disease (SCD) receive optimal medical care, including both management of symptoms of SCD as well as treatments that lessen the severity of the disease. The Sickle Cell Disease Team includes physicians, nurses, nurse practitioners, social work, psychology, and other professionals who contribute to the inpatient and outpatient care of children and young adults with SCD.


  • B.S., Indiana University1996
  • M.D., Washington University School of Medicine2000


  • Residency in Pediatrics, St. Louis Children's Hospital2000 - 2003
  • Fellowship in Pediatric Hematology/Oncology, Washington University School of Medicine2003 - 2006

Licensure and Board Certification

  • IN, Medical Licensing Board2006
  • American Board of Pediatrics2006
  • American Board of Pediatrics, Subboard of Pediatric Hematology-Oncology2009
  • MO, Board of Registration for the Healing Arts2011


  • Best Doctors in St. Louis2015
  • Best Doctors in St. Louis2016

Recent Publications view all (15)

Publication Co-Authors

  1. Hall EM, Leonard J, Smith JL, Guilliams KP, Binkley M, Fallon RJ, Hulbert ML. Reduction in Overt and Silent Stroke Recurrence Rate Following Cerebral Revascularization Surgery in Children with Sickle Cell Disease and Severe Cerebral Vasculopathy. Pediatr Blood Cancer. 2016;63(8):1431-7. PMID:27106860  
  2. Brousseau DC, Scott JP, Badaki-Makun O, Darbari DS, Chumpitazi CE, Airewele GE, Ellison AM, Smith-Whitley K, Mahajan P, Sarnaik SA, Casper TC, Cook LJ, Dean JM, Leonard J, Hulbert ML, Powell EC, Liem RI, Hickey R, Krishnamurti L, Hillery CA, Nimmer M, Panepinto JA, Pediatric Emergency Care Applied Research Network (PECARN). A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children. Blood. 2015. doi:10.1182/blood-2015-05-647107  PMID:26232172  
  3. Fields ME, Hulbert ML, Chen L, Berlin AN, Jackups R, Spinella PC. Red blood cell storage duration is not associated with clinical outcomes for acute chest syndrome in children with sickle cell disease. Transfusion. 2015. doi:10.1111/trf.13176  PMID:26033266  
  4. Kothari A, Hulbert ML, Cottrell CE, Nguyen TT. Aggressive congenital juvenile myelomonocytic leukemia associated with somatic KRAS p.G13D mutation and concurrent germline IGF1R duplication. Leuk Lymphoma. 2015;56(4):1175-8. doi:10.3109/10428194.2014.953152  PMID:25110823  
  5. Beverung LM, Strouse JJ, Hulbert ML, Neville K, Liem RI, Inusa B, Fuh B, King A, Meier ER, Casella J, DeBaun MR, Panepinto JA, SIT trial investigators. Health-related quality of life in children with sickle cell anemia: impact of blood transfusion therapy. Am J Hematol. 2015;90(2):139-43. doi:10.1002/ajh.23877  PMCID:PMC4304929  PMID:25345798  
  6. Guilliams KP, Fields ME, Hulbert ML. Higher-than-expected prevalence of silent cerebral infarcts in children with hemoglobin SC disease. Blood. 2015;125(2):416-7. doi:10.1182/blood-2014-10-605964  PMID:25573975  
  7. Fasano RM, Meier ER, Hulbert ML. Cerebral vasculopathy in children with sickle cell anemia. Blood Cells Mol Dis. 2015;54(1):17-25. doi:10.1016/j.bcmd.2014.08.007  PMID:25294561  
  8. Creary S, Heiny M, Croop J, Fallon R, Vik T, Hulbert M, Knoderer H, Kumar M, Sharathkumar A. Clinical course of postthrombotic syndrome in children with history of venous thromboembolism. Blood Coagul Fibrinolysis. 2012;23(1):39-44. doi:10.1097/MBC.0b013e32834bdb1c  PMID:22089938  
  9. Skiles JL, Imel EA, Christenson JC, Bell JE, Hulbert ML. Fluorosis because of prolonged voriconazole therapy in a teenager with acute myelogenous leukemia. J Clin Oncol. 2011;29(32):e779-82. doi:10.1200/JCO.2011.35.9604  PMID:21969513  
  10. Hulbert ML, McKinstry RC, Lacey JL, Moran CJ, Panepinto JA, Thompson AA, Sarnaik SA, Woods GM, Casella JF, Inusa B, Howard J, Kirkham FJ, Anie KA, Mullin JE, Ichord R, Noetzel M, Yan Y, Rodeghier M, Debaun MR. Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Blood. 2011;117(3):772-9. doi:10.1182/blood-2010-01-261123  PMCID:PMC3035071  PMID:20940417  
  11. Rao A, Hulbert M, Wilson DB. Severe hypertriglyceridemia in an infant with red cell pyruvate kinase deficiency. Indian Pediatr. 2007;44(4):303-5. PMID:17468529  
  12. Hulbert ML, Scothorn DJ, Panepinto JA, Scott JP, Buchanan GR, Sarnaik S, Fallon R, Chu JY, Wang W, Casella JF, Resar L, Berman B, Adamkiewicz T, Hsu LL, Smith-Whitley K, Mahoney D, Woods G, Watanabe M, DeBaun MR. Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: a retrospective cohort study of 137 children with sickle cell anemia. J Pediatr. 2006;149(5):710-2. doi:10.1016/j.jpeds.2006.06.037  PMID:17095350  
  13. Strouse JJ, Hulbert ML, DeBaun MR, Jordan LC, Casella JF. Primary hemorrhagic stroke in children with sickle cell disease is associated with recent transfusion and use of corticosteroids. Pediatrics. 2006;118(5):1916-24. doi:10.1542/peds.2006-1241  PMID:17079562  
  14. Ogden MA, White FV, Hulbert ML, Herrmann BW. Pathology quiz case 1. Cervical neuroblastoma (NB). Arch Otolaryngol Head Neck Surg. 2005;131(2):172, 174. doi:10.1001/archotol.131.2.172  PMID:15723954  
  15. Wilson DB, Rao A, Hulbert M, Mychaliska KP, Luchtman-Jones L, Hill DA, Foglia RP. Neutropenic enterocolitis as a presenting complication of acute lymphoblastic leukemia: an unusual case marked by delayed perforation of the descending colon. J Pediatr Surg. 2004;39(7):e18-20. PMID:15213940  
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