Department of Pediatrics

Education

• BA, Washington University, 1993
• PhD, Washington University School of Medicine, 2001
• MD, Washington University School of Medicine, 2001

Training

• Pediatric Residency Training Program, University of Chicago Children's Hospital, 2001 - 2004
• Pediatric Critical Care Fellowship Program, University of Chicago Children's Hospital, 2004 - 2008
• Pediatric Scientist Development Program Fellow, University of Chicago, 2005 - 2008

Licensure and Board Certification

• 2004 - PresIL, Licensed Physician
• 2004 - 2014American Board of Pediatrics, General Pediatrics
• 2008 - PresAmerican Board of Pediatrics, Pediatric Critical Care Medicine
• 2017 - PresMO, Licensed Physician

Honors and Awards

• The Marion Smith Spector Award for Undergraduate Research, 1993
• Spencer T. and Ann W. Olin Medical Scientist Fellow, 1999
• Pediatric Intern of the Year, 2001 - 2002
• Summa Cum Laude, Washington University, 2003
• Pediatric Senior Resident of the Year, 2003 - 2004
• Pediatric Scientist Development Program Fellow, 2005 - 2008
• Pediatric Fellow Teaching Award, 2008
• Society for Pediatric Research Young Investigator Award, 2011
• Special Emphasis Panel Reviewer, NIAID Partnerships for Biodefense, 2011
• University of Chicago Distinguished Investigator Award, 2011
• Burroughs Wellcome Investigators in the Pathogenesis of Infectious Disease, 2012
• Elected to the American Society for Clinical Investigation, 2012
• Reviewer, NCCAM/NIH Mechanistic Research on CAM Natural Products, 2012
• Ricketts Symposium Lecturer, University of Chicago, 2012
• Ricketts Symposium Lecturer, University of Chicago, 2012
• Shipley Lecturer, Harvard Medical School, 2012
• Reviewer, NIH Clinical Research and Field Studies, 2013 - Pres
• Richard M. Rothberg Faculty Award for Excellence in Patient Care and Resident Education, 2013
• Frontiers in Science Lecturer, American Medical School Pediatric Department Chairs Meeting, 2014
• Academic Leadership Program Fellow, Committee on Institutional Collaboration, The University of Chicago, 2014 - 2015
• Association of American Medical Colleges Council of Faculty and Academic Societies Representative, The University of Chicago, 2014 - 2016
• Elected Representative, Faculty Advisory Committee on Translational Studies, The University of Chicago, 2015 - 2016
• Alpha Omega Alpha (AOA) Honor Medical Society, 2018
• Elected to the Society for Pediatric Research, 2019
• Vice Chair, Gordon Research Conference on Staphylococcal Diseases, 2019
• Academic Women’s Network Mentor Award, Washington University, 2019

Recent Publications view all (10)

1. Hecht AL, Casterline BW, Choi VM, Bubeck Wardenburg J. A Two-Component System Regulates Bacteroides fragilis Toxin to Maintain Intestinal Homeostasis and Prevent Lethal Disease. Cell Host Microbe. 2017. PMID:28943327 
2. Casterline BW, Hecht AL, Choi VM, Bubeck Wardenburg J. The Bacteroides fragilis pathogenicity island links virulence and strain competition. Gut Microbes. 2017;8(4):374-383. PMCID:PMC5570422  PMID:28632016 
3. Seilie ES, Bubeck Wardenburg J. Staphylococcus aureus pore-forming toxins: The interface of pathogen and host complexity. Semin Cell Dev Biol. 2017. PMID:28445785 
4. Doctor A, Zimmerman J, Agus M, Rajasekaran S, Bubeck Wardenburg J, Fortenberry J, Zajicek A, Mairson E, Typpo K. Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies. Pediatr Crit Care Med. 2017;18(3_suppl Suppl 1):S67-S82. PMCID:PMC5333132  PMID:28248836 
5. Sampedro GR, Bubeck Wardenburg J. Staphylococcus aureus in the Intensive Care Unit: Are These Golden Grapes Ripe for a New Approach? J Infect Dis. 2017;215(suppl_1):S64-S70. PMID:28003353 
6. Yu KO, Randolph AG, Agan AA, Yip WK, Truemper EJ, Weiss SL, Ackerman KG, Schwarz AJ, Giuliano JS Jr, Hall MW, Bubeck Wardenburg J, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) PICFlu Study Group., PALISI PICFlu Study Group.. Staphylococcus aureus α-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children. J Infect Dis. 2016;214(11):1638-1646. PMCID:PMC5144732  PMID:27651418 
7. Hecht AL, Casterline BW, Earley ZM, Goo YA, Goodlett DR, Bubeck Wardenburg J. Strain competition restricts colonization of an enteric pathogen and prevents colitis. EMBO Rep. 2016;17(9):1281-91. PMCID:PMC5007561  PMID:27432285 
8. Herrou J, Choi VM, Bubeck Wardenburg J, Crosson S. Activation Mechanism of the Bacteroides fragilis Cysteine Peptidase, Fragipain. Biochemistry. 2016;55(29):4077-84. PMCID:PMC5053104  PMID:27379832 
9. Fiaschi L, Di Palo B, Scarselli M, Pozzi C, Tomaszewski K, Galletti B, Nardi-Dei V, Arcidiacono L, Mishra RP, Mori E, Pallaoro M, Falugi F, Torre A, Fontana MR, Soriani M, Bubeck Wardenburg J, Grandi G, Rappuoli R, Ferlenghi I, Bagnoli F. Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin. Clin Vaccine Immunol. 2016;23(6):442-50. PMCID:PMC4895005  PMID:27030589 
10. Choi VM, Herrou J, Hecht AL, Teoh WP, Turner JR, Crosson S, Bubeck Wardenburg J. Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice. Nat Med. 2016;22(5):563-7. PMCID:PMC4860040  PMID:27089515