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Juliane Bubeck Wardenburg, M.D., Ph.D.
jbubeck@wustl.edu
Division Chief, Critical Care Medicine
Donald B. Strominger Professor
Researcher, Pediatric Research
Critical Care Medicine
Pediatric Research
phone: (314) 454-2527
Education
BA,
Washington University
,
1993
PhD,
Washington University School of Medicine
,
2001
MD,
Washington University School of Medicine
,
2001
Training
Pediatric Residency Training Program, University of Chicago Children's Hospital
,
2001
-
2004
Pediatric Critical Care Fellowship Program, University of Chicago Children's Hospital
,
2004
-
2008
Pediatric Scientist Development Program Fellow, University of Chicago
,
2005
-
2008
Licensure and Board Certification
2004
-
Pres
IL, Licensed Physician
2004
-
2014
American Board of Pediatrics, General Pediatrics
2008
-
Pres
American Board of Pediatrics, Pediatric Critical Care Medicine
2017
-
Pres
MO, Licensed Physician
Honors and Awards
The Marion Smith Spector Award for Undergraduate Research
,
1993
Spencer T. and Ann W. Olin Medical Scientist Fellow
,
1999
Pediatric Intern of the Year
,
2001
- 2002
Summa Cum Laude, Washington University
,
2003
Pediatric Senior Resident of the Year
,
2003
- 2004
Pediatric Scientist Development Program Fellow
,
2005
- 2008
Pediatric Fellow Teaching Award
,
2008
Society for Pediatric Research Young Investigator Award
,
2011
Special Emphasis Panel Reviewer, NIAID Partnerships for Biodefense
,
2011
University of Chicago Distinguished Investigator Award
,
2011
Burroughs Wellcome Investigators in the Pathogenesis of Infectious Disease
,
2012
Elected to the American Society for Clinical Investigation
,
2012
Reviewer, NCCAM/NIH Mechanistic Research on CAM Natural Products
,
2012
Ricketts Symposium Lecturer, University of Chicago
,
2012
Ricketts Symposium Lecturer, University of Chicago
,
2012
Shipley Lecturer, Harvard Medical School
,
2012
Reviewer, NIH Clinical Research and Field Studies
,
2013
- Pres
Richard M. Rothberg Faculty Award for Excellence in Patient Care and Resident Education
,
2013
Frontiers in Science Lecturer, American Medical School Pediatric Department Chairs Meeting
,
2014
Academic Leadership Program Fellow, Committee on Institutional Collaboration, The University of Chicago
,
2014
- 2015
Association of American Medical Colleges Council of Faculty and Academic Societies Representative, The University of Chicago
,
2014
- 2016
Elected Representative, Faculty Advisory Committee on Translational Studies, The University of Chicago
,
2015
- 2016
Alpha Omega Alpha (AOA) Honor Medical Society
,
2018
Elected to the Society for Pediatric Research
,
2019
Vice Chair, Gordon Research Conference on Staphylococcal Diseases
,
2019
Academic Women’s Network Mentor Award, Washington University
,
2019
Association of American Physicians
,
2020
Recent Publications
view all (11)
Lee, B., Olaniyi, R., Kwiecinski, J. and Bubeck Wardenburg, J. .
Staphylococcus aureus
alpha-toxin suppresses antigen-specific T cell responses.
Journal of Clinical Investigation
.
2020.
Hecht AL, Casterline BW, Choi VM, Bubeck Wardenburg J.
A Two-Component System Regulates Bacteroides fragilis Toxin to Maintain Intestinal Homeostasis and Prevent Lethal Disease.
Cell Host Microbe
.
2017.
PMID:
28943327
Casterline BW, Hecht AL, Choi VM, Bubeck Wardenburg J.
The Bacteroides fragilis pathogenicity island links virulence and strain competition.
Gut Microbes
.
2017;8
(4):
374-383.
PMCID:
PMC5570422
PMID:
28632016
Seilie ES, Bubeck Wardenburg J.
Staphylococcus aureus pore-forming toxins: The interface of pathogen and host complexity.
Semin Cell Dev Biol
.
2017.
PMID:
28445785
Doctor A, Zimmerman J, Agus M, Rajasekaran S, Bubeck Wardenburg J, Fortenberry J, Zajicek A, Mairson E, Typpo K.
Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies.
Pediatr Crit Care Med
.
2017;18
(3_suppl Suppl 1):
S67-S82.
PMCID:
PMC5333132
PMID:
28248836
Sampedro GR, Bubeck Wardenburg J.
Staphylococcus aureus in the Intensive Care Unit: Are These Golden Grapes Ripe for a New Approach?
J Infect Dis
.
2017;215
(suppl_1):
S64-S70.
PMID:
28003353
Yu KO, Randolph AG, Agan AA, Yip WK, Truemper EJ, Weiss SL, Ackerman KG, Schwarz AJ, Giuliano JS Jr, Hall MW, Bubeck Wardenburg J, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) PICFlu Study Group., PALISI PICFlu Study Group..
Staphylococcus aureus α-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children.
J Infect Dis
.
2016;214
(11):
1638-1646.
PMCID:
PMC5144732
PMID:
27651418
Hecht AL, Casterline BW, Earley ZM, Goo YA, Goodlett DR, Bubeck Wardenburg J.
Strain competition restricts colonization of an enteric pathogen and prevents colitis.
EMBO Rep
.
2016;17
(9):
1281-91.
PMCID:
PMC5007561
PMID:
27432285
Herrou J, Choi VM, Bubeck Wardenburg J, Crosson S.
Activation Mechanism of the Bacteroides fragilis Cysteine Peptidase, Fragipain.
Biochemistry
.
2016;55
(29):
4077-84.
PMCID:
PMC5053104
PMID:
27379832
Fiaschi L, Di Palo B, Scarselli M, Pozzi C, Tomaszewski K, Galletti B, Nardi-Dei V, Arcidiacono L, Mishra RP, Mori E, Pallaoro M, Falugi F, Torre A, Fontana MR, Soriani M, Bubeck Wardenburg J, Grandi G, Rappuoli R, Ferlenghi I, Bagnoli F.
Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin.
Clin Vaccine Immunol
.
2016;23
(6):
442-50.
PMCID:
PMC4895005
PMID:
27030589
Choi VM, Herrou J, Hecht AL, Teoh WP, Turner JR, Crosson S, Bubeck Wardenburg J.
Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice.
Nat Med
.
2016;22
(5):
563-7.
PMCID:
PMC4860040
PMID:
27089515
Last updated: 11/18/2020
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