Green Lab

Investigating the origins of genome instability in childhood cancers, our lab seeks to understand how DNA damage responses shape tumor development and therapeutic outcomes. Unlike adult malignancies driven by aging or environmental carcinogens, pediatric cancers arise through distinct mechanisms that remain poorly understood. Our long-term goal is to identify predictors of mutagenesis and uncover vulnerabilities within DNA damage response pathways, paving the way for innovative treatments that improve survival and quality of life for children with cancer.