Polineni Lab

Exploring mechanisms of lung disease and identifying non-CFTR modifiers that influence severity, our lab focuses on airway disorders such as cystic fibrosis to uncover biological pathways driving disease progression. Using molecular biology, genetics, biochemistry and bioinformatics, we investigate factors beyond CFTR that shape inflammatory and immune responses in airway epithelia. Through genomics, multi-omics analyses and translational research, we aim to develop innovative therapeutic targets and personalized strategies to improve outcomes for people with CF and related conditions.