Di Paola Lab

Discovering genetic and biological determinants of bleeding and thrombosis our lab combines expertise in genomics, bioinformatics and molecular biology to uncover mechanisms underlying disorders such as von Willebrand disease and platelet dysfunction. We develop interactive genomic databases, investigate mutations like NBEAL2 and ETV6 and use CRISPR-modified mice to study hemostasis. Our goal is to translate these insights into novel therapies that improve quality of life for patients with bleeding and thrombotic disorders.