Kristin Guilliams, MD MSCI

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Assistant Professor of Pediatrics, Critical Care Medicine
Assistant Professor, Neurology
Assistant Professor, Radiology
NeurologyCritical Care MedicineRadiology



  • BS, cum laude, Furman University2002
  • MD, University of Virginia2006
  • MSCI, Washington University in St. Louis2016


  • Pediatric Residency, Washington University in St. Louis2006 - 2008
  • Pediatric Neurology Residency, Washington University in St. Louis2008 - 2011
  • Pediatric Critical Care Fellowship, Washington University in St. Louis2011 - 2014

Licensure and Board Certification

  • 2011 - PresMO, Missouri Medical License
  • 2011 - PresAmerican Board of Psychiatry and Neurology with Child Specialization
  • 2012 - PresAmerican Board of Pediatrics: General Pediatrics
  • 2013 - PresPALS Instructor
  • 2014 - PresAmerican Board of Pediatrics: Pediatric Critical Care Medicine
  • 2021 - PresIL, Licensed Physician and Surgeon

Honors and Awards

  • Steven M Rothman Award (Outstanding Teaching by Pediatric Neurology Resident)2010
  • Child Neurology Foundation PERF Scientific Award2015
  • Neurology Clerkship Student Teaching Award Honor Roll2020
  • Jean Holowach Thurston Award2022

Recent Publications view all (66)

Publication Co-Authors

  1. Prevalence and Risk Factors of Neurologic Manifestations in Hospitalized Children Diagnosed with Acute SARS-CoV-2 or MIS-C. Pediatr Neurol. 2022;128:33-44. PMCID:PMC8713420  PMID:35066369 
  2. Magnetic resonance imaging adds prognostic value to EEG after pediatric cardiac arrest. Resuscitation. 2022;173:91-100. PMID:35227820 
  3. Cerebral oxygen metabolic stress is increased in children with sickle cell anemia compared to anemic controls. Am J Hematol. 2022. PMID:35113471 
  4. Renal Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S66-S73. PMID:34970682 
  5. Hematologic Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S74-S78. PMID:34970675 
  6. Scoring Systems for Organ Dysfunction and Multiple Organ Dysfunction: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S23-S31. PMID:34970683 
  7. Patterns of Organ Dysfunction in Critically Ill Children Based on PODIUM Criteria. Pediatrics. 2022;149(1 Suppl 1):S103-S110. PMID:34970678 
  8. Endocrine Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S84-S90. PMID:34970672 
  9. Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S91-S98. PMID:34970674 
  10. Acute Liver Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S59-S65. PMID:34970684 
  11. Cardiovascular Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S39-S47. PMID:34970677 
  12. Coagulation Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S79-S83. PMID:34970670 
  13. Refining the Pediatric Multiple Organ Dysfunction Syndrome. Pediatrics. 2022;149(1 Suppl 1):S13-S22. PMID:34970671 
  14. Respiratory Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S48-S52. PMID:34970679 
  15. Endothelial Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S97-S102. PMID:34970676 
  16. Acute Neurologic Dysfunction in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022;149(1 Suppl 1):S32-S38. PMID:34970681 
  17. Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Pediatrics. 2022;149(1 Suppl 1):S1-S12. PMID:34970673 
  18. Pediatric hospital proximity to endovascular thrombectomy centers in the United States. Interv Neuroradiol. 2021;15910199211059334. PMID:34913385 
  19. MR Imaging Differences in the Circle of Willis between Healthy Children and Adults. AJNR Am J Neuroradiol. 2021;42(11):2062-2069. PMCID:PMC8583273  PMID:34556478 
  20. Cognitive Dysfunction After Analgesia and Sedation: Out of the Operating Room and Into the Pediatric Intensive Care Unit. Front Behav Neurosci. 2021;15:713668. PMCID:PMC8415404  PMID:34483858 
  21. Behavioral and cognitive functioning in individuals with Cantú syndrome. Am J Med Genet A. 2021;185(8):2434-2444. PMID:34056838 
  22. Cerebral Oxygen Metabolic Stress, Microstructural Injury, and Infarction in Adults With Sickle Cell Disease. Neurology. 2021. PMID:34172536 
  23. Bulk volume susceptibility difference between deoxyhemoglobin and oxyhemoglobin for HbA and HbS: A comparative study. Magn Reson Med. 2021;85(6):3383-3393. PMCID:PMC7945010  PMID:33475200 
  24. Immediate Postoperative Electroencephalography Monitoring in Pediatric Moyamoya Disease and Syndrome. Pediatr Neurol. 2021;118:40-45. PMID:33773289 
  25. Pediatric Thrombectomy: Design and Workflow Lessons From Two Experienced Centers. Stroke. 2021;52(4):1511-1519. PMCID:PMC7987698  PMID:33691502 
  26. Macroperiodic Oscillations Are Associated With Seizures Following Acquired Brain Injury in Young Children. J Clin Neurophysiol. 2021. PMID:33587388 
  27. Neurocritical Care of the Pregnant Patient. Curr Treat Options Neurol. 2021;23(7):22. PMCID:PMC8214980  PMID:34177249 
  28. Seizures Are Associated With Brain Injury in Infants Undergoing Extracorporeal Membrane Oxygenation. J Child Neurol. 2020;883073820966917. PMID:33112194 
  29. Functional Connectivity Decreases with Metabolic Stress in Sickle Cell Disease. Ann Neurol. 2020. PMID:32869335 
  30. Pediatric Neurocritical Care: From Field to Follow-Up. Pediatr Neurol. 2020;108:1-2. PMCID:PMC7307635  PMID:31902549 
  31. Neurological Monitoring and Complications of Pediatric Extracorporeal Membrane Oxygenation Support. Pediatr Neurol. 2020;108:31-39. PMID:32299748 
  32. Variation in Treatment and Outcomes of Children With Acute Disseminated Encephalomyelitis. Hosp Pediatr. 2020;10(2):159-165. PMID:31996356 
  33. Cerebrovascular Complications of Pediatric Blunt Trauma. Pediatr Neurol. 2020. PMID:32111560 
  34. Sleep Measure Validation in a Pediatric Neurocritical Care Acquired Brain Injury Population. Neurocrit Care. 2019. PMID:31797275 
  35. Seizures and Outcome One Year After Neonatal and Childhood Cerebral Sinovenous Thrombosis. Pediatr Neurol. 2019. PMID:31882182 
  36. Higher executive abilities following a blood transfusion in children and young adults with sickle cell disease. Pediatr Blood Cancer. 2019;66(10):e27899. doi:10.1002/pbc.27899  PMCID:PMC6707832  PMID:31267645 
  37. Characteristics and Outcome in Children With Craniectomy Following Acute Ischemic Stroke in the International Pediatric Stroke Study. J Child Neurol. 2019;34(12):765-769. PMID:31282248 
  38. Postintensive Care Syndrome in Pediatric Critical Care Survivors: Therapeutic Options to Improve Outcomes After Acquired Brain Injury. Curr Treat Options Neurol. 2019;21(10):49. PMID:31559490 
  39. Sleep-Wake Disturbances After Acquired Brain Injury in Children Surviving Critical Care. Pediatr Neurol. 2019. PMID:31735567 
  40. Arterial Ischemic Stroke Secondary to Cardiac Disease in Neonates and Children. Pediatr Neurol. 2019. PMID:31371125 
  41. Cardiac Arrest Outcomes in Children With Preexisting Neurobehavioral Impairment. Pediatr Crit Care Med. 2019;20(6):510-517. PMCID:PMC6548585  PMID:30807545 
  42. Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia. Blood. 2019;133(22):2436-2444. PMCID:PMC6543515  PMID:30858231 
  43. Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Stroke. 2019;50(5):1089-1094. PMCID:PMC6481313  PMID:31009343 
  44. Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease. Stroke. 2019;50(2):266-273. PMCID:PMC6385587  PMID:30661504 
  45. Optimizing Neurocritical Care Follow-Up Through the Integration of Neuropsychology. Pediatr Neurol. 2018;89:58-62. PMID:30442440 
  46. Silent infarcts in sickle cell anemia occur in the borderzone region and are associated with low cerebral blood flow. Blood. 2018. PMID:30061156 
  47. Neurologic outcomes in pediatric cardiac arrest survivors enrolled in the THAPCA trials. Neurology. 2018;91(2):e123-e131. PMCID:PMC6053110  PMID:29884735 
  48. Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease. Neurology. 2018;90(13):e1134-e1142. PMCID:PMC5880632  PMID:29500287 
  49. Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia. Blood. 2018;131(9):1012-1021. PMCID:PMC5833262  PMID:29255068 
  50. Harnessing Neuroimaging Capability in Pediatric Stroke: Proceedings of the Stroke Imaging Laboratory for Children Workshop. Pediatr Neurol. 2017;69:3-10. PMID:28259513 
  51. Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy. Pediatr Neurol. 2017;69:49-57. PMCID:PMC5365370  PMID:28159432 
  52. Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children. N Engl J Med. 2017;376(4):318-329. PMCID:PMC5310766  PMID:28118559 
  53. Prolonged or recurrent acute seizures after pediatric arterial ischemic stroke are associated with increasing epilepsy risk. Dev Med Child Neurol. 2017;59(1):38-44. PMID:27422813 
  54. Pediatric Out-of-Hospital Cardiac Arrest Characteristics and Their Association With Survival and Neurobehavioral Outcome. Pediatr Crit Care Med. 2016;17(12):e543-e550. PMCID:PMC5138073  PMID:27679965 
  55. Functional Outcome Trajectories After Out-of-Hospital Pediatric Cardiac Arrest. Crit Care Med. 2016;44(12):e1165-e1174. PMCID:PMC5129173  PMID:27509385 
  56. Reduction in Overt and Silent Stroke Recurrence Rate Following Cerebral Revascularization Surgery in Children with Sickle Cell Disease and Severe Cerebral Vasculopathy. Pediatr Blood Cancer. 2016;63(8):1431-7. PMCID:PMC5443666  PMID:27106860 
  57. Targeted Temperature Management After Pediatric Cardiac Arrest Due To Drowning: Outcomes and Complications. Pediatr Crit Care Med. 2016;17(8):712-20. PMCID:PMC5123789  PMID:27362855 
  58. Pathophysiology and Management of Moderate and Severe Traumatic Brain Injury in Children. J Child Neurol. 2016;31(1):35-45. PMID:25512361 
  59. Emergency Neurological Life Support: Acute Ischemic Stroke. Neurocrit Care. 2015;23 Suppl 2:S94-102. PMID:26438453 
  60. Therapeutic hypothermia after out-of-hospital cardiac arrest in children. N Engl J Med. 2015;372(20):1898-908. PMCID:PMC4470472  PMID:25913022 
  61. Higher-than-expected prevalence of silent cerebral infarcts in children with hemoglobin SC disease. Blood. 2015;125(2):416-7. PMID:25573975 
  62. Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium. Pediatr Neurol. 2015;52(1):5-15. PMCID:PMC4936915  PMID:25532775 
  63. Hypothermia for pediatric refractory status epilepticus. Epilepsia. 2013;54(9):1586-94. PMCID:PMC3975144  PMID:23906244 
  64. Clinical, neurological, and electrophysiological features of nodding syndrome in Kitgum, Uganda: an observational case series. Lancet Neurol. 2013;12(2):166-74. PMID:23305742 
  65. A purpuric rash and mononeuritis multiplex. Am Fam Physician. 2008;77(4):501-2. PMID:18326170 
  66. Magnetic resonance imaging differences in the circle of Willis between healthy children and adults AJNR. 
Last updated: 04/16/2022
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