Jeffrey Magee, M.D., Ph.D.

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Associate Professor, Division of Hematology-Oncology, Department of Pediatrics
Hematology and Oncology

phone: (314) 454-6018


  • BS, University of Wisconsin1997
  • MD, Washington University, School of Medicine2005
  • PhD, Washington University, School of Medicine2005


  • Residency, University of Michigan Hospitals and Health Centers2005 - 2007
  • Fellowship, University of Michigan Hospitals and Health Centers2007 - 2010

Licensure and Board Certification

  • 2009 - PresGeneral Pediatrics, # 95246
  • 2009 - 2013MI, Michigan Medical Board
  • 2011 - PresPediatric Hematology/Oncology, # 2409
  • 2011 - 2015TX, Texas Medical Board
  • 2013 - PresMO, Missouri Board of Registration for the Healing Arts

Honors and Awards

  • Hilldale Undergraduate/Faculty Research Fellowship, University of Wisconsin-Madison1995
  • Barry M. Goldwater Scholarship, University of Wisconsin-Madison1996
  • Howard Hughes Medical Institute Fellowship, University of Wisconsin-Madison1996
  • I. Jerome Flance Medical Science Traineeship, Washington University School of Medicine1999
  • American College of Physicians Award for Excellence in Physical Diagnosis, Washington University School of Medicine2000
  • Outstanding Teaching Assistant, Washington University School of Medicine2000
  • David M. Kipnis Thesis Award, Washington University School of Medicine2005
  • Spencer T. and Ann W. Olin Medical Science Fellowship, Washington University School of Medicine2005
  • Pediatric Scientist Development Program Fellowship, University of Michigan Medical School2008
  • Laurence Carolin Award, University of Michigan Medical School2010
  • UT-Southwestern Disease Oriented Clinical Scholar Fellowship (declined)2013
  • Children's Discovery Institute Faculty Scholar2014
  • Hyundai Hope Scholar2014
  • St. Baldrick's Scholar Award2014
  • Gabrielle's Angel Medical Research Award2016
  • V Foundation Scholar Award2016
  • Alex's Lemonade Stand Foundation 'A' Award2016
  • American Society of Hematology Junior Faculty Scholar Award2016
  • Hyundai hope Scholar2019
  • Leukemia Lymphoma Society Scholar2021

Recent Publications view all (30)

Publication Co-Authors

  1. Single-cell RNA transcriptome analysis of CNS immune cells reveals CXCL16/CXCR6 as maintenance factors for tissue resident T cells that drive synapse elimination during viral recovery Genome Medicine. 2022;14:108. PMID:36153630 
  2. Macrophage NOX2 NADPH oxidase maintains alveolar homeostasis in mice Blood. 2022;139:2855-2870. PMCID:PMC9101249  PMID:35357446 
  3. A Somatic mutation in Moesin drives progression into acute myeloid leukemia Science Advances. 2022;8:eabm9987. PMCID:PMC9020775  PMID:35442741 
  4. Transcriptional reprogramming in neonatal hematopoietic stem and progenitor cells Experimental Hematology. 2021. doi:10.1016/j.exphem.2021.07.004  PMID:34303776 
  5. Pediatric Hodgkin Lymphoma, Version 3.2021 Journal of the National Comprehensive Cancer Center Network. 2021;19:733-754. doi:10.6004/jnccn.2021.0027   PMID: 34214968 
  6. Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-risk Leukemias: A Report from the LEAP Consortium Cancer Discovery. 2021;11:1424-1439. doi:10.1158/2159-8290.CD-20-0564  PMID:33563661 
  7. Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy Cell Reports. 2021;34:108751. doi:10.1016/j.celrep.2021.108751  PMID:33596429 
  8. Developmental stage-specific changes in protein synthesis differentially sensitize hematopoietic stem cells and erythroid progenitors to impaired ribosome biogenesis Stem Cell Reports. 2021;16:20-28. doi:10.1016/j.stemcr.2020.11.017  PMCID:33440178  
  9. Single-cell analysis of neonatal HSC ontogeny reveals gradual and uncoordinated transcriptional reprogramming that begins before birth Cell Stem Cell. 2020;27:732-747. doi:10.1016/j.stem.2020.08.001   PMID:32822583 
  10. TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS Experimental Hematology. 2020;88:42-55. doi:10.1016/j.exphem.2020.07.001   PMID:32652111 
  11. The efficiency of murine MLL-ENL driven leukemia initiation changes with age and peaks during neonatal development. Blood Advances. 2019;3(15):2388-2399. PMCID:PMC6693010  PMID:31405949 
  12. PRKCH regulates hematopoietic stem cell function and predicts poor prognosis in acute myeloid leukemia. Exp Hematol. 2017. PMID:28596089 
  13. Sleepwalking stem cells. Blood. 2017;129(14):1887-1888. PMCID:PMC5383876  PMID:28385766 
  14. Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations. Elife. 2016;5. PMID:27879203 
  15. Comment on: Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia. Br J Haematol. 2016. PMID:27766614 
  16. Pten cell autonomously modulates the hematopoietic stem cell response to inflammatory cytokines Stem Cell Reports. 2016;6(6):806-814. PMID:27185281 
  17. Protein kinase N3 deficiency impedes PI3-kinase pathway-driven leukemogenesis without affecting normal hematopoiesis. Leukemia. 2015;29(1):255-8. doi:10.1038/leu.2014.278  PMID:25234167 
  18. Haematopoietic stem cells require a highly regulated protein synthesis rate. Nature. 2014;509(7498):49-54. doi:10.1038/nature13035  PMCID:PMC4015626  PMID:24670665 
  19. Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness. Nature. 2013;504(7478):143-7. doi:10.1038/nature12830  PMID:24284627 
  20. Expression of BCR/ABL p210 from a knockin allele enhances bone marrow engraftment without inducing neoplasia. Cell Rep. 2013;5(1):51-60. doi:10.1016/j.celrep.2013.08.037  PMCID:PMC3832111  PMID:24095735 
  21. Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression. Cell Stem Cell. 2012;11(3):415-28. doi:10.1016/j.stem.2012.05.026  PMCID:PMC3447536  PMID:22958933 
  22. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell. 2012;21(3):283-96. doi:10.1016/j.ccr.2012.03.003  PMID:22439924 
  23. A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles. Genome Res. 2006;16(3):405-13. doi:10.1101/gr.4303406  PMCID:PMC1415218  PMID:16449500 
  24. Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element. Endocrinology. 2006;147(1):590-8. doi:10.1210/en.2005-1001  PMID:16210365 
  25. Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation. Cancer Cell. 2003;3(3):273-83. PMID:12676585 
  26. Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia. Mol Cell Biol. 2002;22(5):1495-503. PMCID:PMC134699  PMID:11839815 
  27. Bringing the human genome and the revolution in bioinformatics to the medical school classroom: a case report from Washington University School of Medicine. Acad Med. 2001;76(8):852-5. PMID:11500292 
  28. Expression profiling reveals hepsin overexpression in prostate cancer. Cancer Res. 2001;61(15):5692-6. PMID:11479199 
  29. Intercompartmental signaling and the regulation of vestigial expression at the dorsoventral boundary of the developing Drosophila wing. Cold Spring Harb Symp Quant Biol. 1997;62:283-91. PMID:9598362 
  30. Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature. 1996;382(6587):133-8. doi:10.1038/382133a0  PMID:8700202 
Last updated: 11/06/2022
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