Singh A, Potani I, Griswold SP, Suri D, Langlois B, Shen Y, Walton SM, Kwan Ho Chui K, Manary MJ, Webb P, Rogers BL, Rosenberg IH. Host Fecal mRNAs Predicted Environmental Enteric Dysfunction among Children with Moderate Acute Malnutrition in Sierra Leone. Am J Trop Med Hyg. 2021. PMID:34460425 Sorkin JD, Manary M, Smeets PAM, MacFarlane AJ, Astrup A, Prigeon RL, Hogans BB, Odle J, Davis TA, Tucker KL, Duggan CP, Tobias DK. A guide for authors and readers of the American Society for Nutrition Journals on the proper use of P values and strategies that promote transparency and improve research reproducibility. Am J Clin Nutr. 2021. PMID:34258613 Griswold SP, Langlois BK, Shen Y, Cliffer IR, Suri DJ, Walton S, Chui K, Rosenberg IH, Koroma AS, Wegner D, Hassan A, Manary MJ, Vosti SA, Webb P, Rogers BL. Effectiveness and cost-effectiveness of 4 supplementary foods for treating moderate acute malnutrition: results from a cluster-randomized intervention trial in Sierra Leone. Am J Clin Nutr. 2021. PMID:34020452 Lelijveld N, Godbout C, Krietemeyer D, Los A, Wegner D, Hendrixson DT, Bandsma R, Koroma A, Manary M. Treating high-risk moderate acute malnutrition using therapeutic food compared with nutrition counseling (Hi-MAM Study): a cluster-randomized controlled trial. Am J Clin Nutr. 2021. PMID:33963734 Schaefer R, Mayberry A, Briend A, Manary M, Walker P, Stobaugh H, Hanson K, McGrath M, Black R. Relapse and regression to severe wasting in children under 5 years: A theoretical framework. Matern Child Nutr. 2021;17(2):e13107. PMCID:PMC7988852 PMID:33145990 Singh A, Ghosh S, Ward H, Manary MJ, Rogers BL, Rosenberg IH. Biomarkers of environmental enteric dysfunction are differently associated with recovery and growth among children with moderate acute malnutrition in Sierra Leone. Am J Clin Nutr. 2021. PMID:33668048 Bierut T, Duckworth L, Grabowsky M, Ordiz MI, Laury ML, Callaghan-Gillespie M, Maleta K, Manary MJ. The effect of bovine colostrum/egg supplementation compared with corn/soy flour in young Malawian children: a randomized, controlled clinical trial. Am J Clin Nutr. 2021;113(2):420-427. PMID:33330913 Stephenson KB, Agapova SE, Hendrixson DT, Koroma AS, Manary MJ. An Optimized Dose of Therapeutic Feeding Results in Noninferior Growth in Midupper Arm Circumference Compared with a Standard Dose in Children in Sierra Leone Recovering from Acute Malnutrition. Curr Dev Nutr. 2021;5(2):nzab007. PMCID:PMC7904386 PMID:33659773 Chen D, McKune SL, Singh N, Yousuf Hassen J, Gebreyes W, Manary MJ, Bardosh K, Yang Y, Diaz N, Mohammed A, Terefe Y, Roba KT, Ketema M, Ameha N, Assefa N, Rajashekara G, Deblais L, Ghanem M, Yimer G, Havelaar AH. Campylobacter Colonization, Environmental Enteric Dysfunction, Stunting, and Associated Risk Factors Among Young Children in Rural Ethiopia: A Cross-Sectional Study From the Campylobacter Genomics and Environmental Enteric Dysfunction (CAGED) Project. Front Public Health. 2021;8:615793. PMCID:PMC7862945 PMID:33553097 Woeltje M, Evanoff A, Culbertson D, Helmink B, Maleta K, Manary MJ, Trehan I. Community-Based Management of Acute Malnutrition in Infants Under 6 Months of Age Current Developments in Nutrition. 2020;4(Issue Supplement_2):1102. doi:https://doi.org/10.1093/cdn/nzaa054_174 Roediger R, Hendrixson DT, Manary MJ. A roadmap to reduce stunting. Am J Clin Nutr. 2020. PMID:32851394 Gauglitz J, Bittremieux W, Williams CL, Weldon KC, Panitchpakdi M, Di Ottavio F, Aceves CM, Brown E, Sikora NC, Jarmusch AK, Martino C, Tripathi A, Sayyari E, Shaffer JP, Coras R, Vargas F, DeRight Goldasich L, Schwartz T, Bryant M, Humphrey G, Johnson AJ, Spengler K, Belda-Ferre P, Diaz E, McDonald D, Zhu O, Nguyen DS, Elijah EO, Wang M, Marotz C, Sprecher KE, Vargas Robles D, Withrow D, Ackermann G, Herrera L, Bradford BJ, Marques L, Amaral JG, Silva RM, Veras FP, Cunha TM, Oliveira RDR, Louzada-Junior P, Mills RH, Galasko D, Dulai PS, Wittenberg C, Gonzalez DJ, Terkeltaub R, Doty MM, Kim JH, Rhee KE, Beauchamp-Walters J, Wright Jr KP, Dominguez-Bello MG, Manary MJ, Oliveira MF, Boland BS, Lopes NP, Guma M, Swafford AD, Dutton RJ,Knight R,Dorrestein PC. Reference data based insights expand understanding of human metabolomes bioRxiv. 2020. doi:https://doi.org/10.1101/2020.07.08.194159 Woodworth MH. mSphere of Influence: Microbiome-Associated Phenotypes Are Modifiable. mSphere. 2020;5(4). PMCID:PMC7333575 PMID:32611702 Bailey J, Opondo C, Lelijveld N, Marron B, Onyo P, Musyoki EN, Adongo SW, Manary M, Briend A, Kerac M. A simplified, combined protocol versus standard treatment for acute malnutrition in children 6-59 months (ComPAS trial): A cluster-randomized controlled non-inferiority trial in Kenya and South Sudan. PLoS Med. 2020;17(7):e1003192. PMCID:PMC7347103 PMID:32645109 Chase RP, Kerac M, Grant A, Manary M, Briend A, Opondo C, Bailey J. Acute malnutrition recovery energy requirements based on mid-upper arm circumference: Secondary analysis of feeding program data from 5 countries, Combined Protocol for Acute Malnutrition Study (ComPAS) Stage 1. PLoS One. 2020;15(6):e0230452. PMCID:PMC7269364 PMID:32492023 Zuzarte A, Mui M, Ordiz MI, Weber J, Ryan K, Manary MJ. Reducing Oil Separation in Ready-to-Use Therapeutic Food. Foods. 2020;9(6). PMCID:PMC7353625 PMID:32492836 Desai C, Handley SA, Rodgers R, Rodriguez C, Ordiz MI, Manary MJ, Holtz LR. Growth velocity in children with Environmental Enteric Dysfunction is associated with specific bacterial and viral taxa of the gastrointestinal tract in Malawian children. PLoS Negl Trop Dis. 2020;14(6):e0008387. PMCID:PMC7310680 PMID:32574158 Grenov B, Larnkjær A, Lee R, Serena A, Mølgaard C, Michaelsen KF, Manary MJ. Circulating Insulin-Like Growth Factor-1 Is Positively Associated with Growth and Cognition in 6- to 9-Year-Old Schoolchildren from Ghana. J Nutr. 2020;150(6):1405-1412. PMID:32211798 Roediger R, Stein HH, Callaghan-Gillespie M, Blackman JK, Kohlmann K, Maleta K, Manary M. Protein quality in ready-to-use supplementary foods for moderate wasting. Matern Child Nutr. 2020;e13019. PMID:32426949 Terefe Y, Deblais L, Ghanem M, Helmy YA, Mummed B, Chen D, Singh N, Ahyong V, Kalantar K, Yimer G, Yousuf Hassen J, Mohammed A, McKune SL, Manary MJ, Ordiz MI, Gebreyes W, Havelaar AH, Rajashekara G. Co-occurrence of Campylobacter Species in Children From Eastern Ethiopia, and Their Association With Environmental Enteric Dysfunction, Diarrhea, and Host Microbiome. Front Public Health. 2020;8:99. PMCID:PMC7174729 PMID:32351922 Mark Manary, Donna Wegner, D Taylor Hendrixson, Rebecca Roediger, Meghan Callaghan. Concerns that The Lancet double-burden series may undermine moderate wasting treatment Field Exchange. 2020;(62):19.
Ordiz MI, Janssen S, Humphrey G, Ackermann G, Stephenson K, Agapova S, Divala O, Kaimila Y, Maleta K, Zhong C, Knight R, Trehan I, Tarr PI, Rusconi B, Manary MJ. The effect of legume supplementation on the gut microbiota in rural Malawian infants aged 6 to 12 months. Am J Clin Nutr. 2020;111(4):884-892. PMID:32047925 Hendrixson DT, Godbout C, Los A, Callaghan-Gillespie M, Mui M, Wegner D, Bryant T, Koroma A, Manary MJ. Treatment of severe acute malnutrition with oat or standard ready-to-use therapeutic food: a triple-blind, randomised controlled clinical trial. Gut. 2020. PMID:32179568 Manary M, Callaghan-Gillespie M. Role of Optimized Plant Protein Combinations as a Low-Cost Alternative to Dairy Ingredients in Foods for Prevention and Treatment of Moderate Acute Malnutrition and Severe Acute Malnutrition. Nestle Nutr Inst Workshop Ser. 2020;93:111-120. PMID:31991424 Schulze KV, Swaminathan S, Howell S, Jajoo A, Lie NC, Brown O, Sadat R, Hall N, Zhao L, Marshall K, May T, Reid ME, Taylor-Bryan C, Wang X, Belmont JW, Guan Y, Manary MJ, Trehan I, McKenzie CA, Hanchard NA. Edematous severe acute malnutrition is characterized by hypomethylation of DNA. Nat Commun. 2019;10(1):5791. PMCID:PMC6923441 PMID:31857576 Bailey J, Opondo C, Lelijveld N, Marron B, Onyoo P, Musyoki E, Adongo S, Briend A, Manary MJ, Kerac M. Combined Protocol for Acute Malnutrition Study (ComPAS) dataset London School of Hygiene & Tropical Medicine. 2019. doi:https://doi.org/10.17037/DATA.00001151 Balamurugan R, Pugazhendhi S, Balachander GM, Dharmalingam T, Mortimer EK, Gopalsamy GL, Woodman RJ, Meng R, Alpers DH, Manary M, Binder HJ, Brown IL, Young GP, Ramakrishna BS. Effect of Native and Acetylated Dietary Resistant Starches on Intestinal Fermentative Capacity of Normal and Stunted Children in Southern India. Int J Environ Res Public Health. 2019;16(20). PMCID:PMC6843365 PMID:31618992 Ordiz MI, Semba RD, Moaddel R, Rolle-Kampczyk U, von Bergen M, Herberth G, Khadeer M, Röder S, Manary MJ. Serum Amino Acid Concentrations in Infants from Malawi are Associated with Linear Growth. Curr Dev Nutr. 2019;3(10):nzz100. PMCID:PMC6785685 PMID:31620672 Barnell EK, Kang Y, Wurtzler EM, Griffith M, Chaudhuri AA, Griffith OL, Geneoscopy Scientists.. Noninvasive Detection of High-Risk Adenomas Using Stool-Derived Eukaryotic RNA Sequences as Biomarkers. Gastroenterology. 2019;157(3):884-887.e3. PMCID:PMC6707888 PMID:31154021 Lelijveld N, Hendrixson DT, Godbout C, Los A, Leppänen JM, Koroma A, Manary MJ. Defining and treating “high-risk” moderate acute malnutrition using expanded admission criteria (Hi-MAM Study): A cluster-randomised controlled trial protocol Field Exchange. 2019;(60):64.
Kureishy S, Callaghan-Gillespie M, Khan GN, Habib A, Jenkins M, Ahmed KM, Achakzai B, Pee S, Manary MJ, Garzon C, Soofi S. Comparison of treatment of severe acute malnutrition with ready-to-use therapeutic food and ready-to-use-supplementary food: Research plans in Pakistan Field Exchange. 2019;(60):50-51.
Kohlmann K, Callaghan-Gillespie M, Gauglitz JM, Steiner-Asiedu M, Saalia K, Edwards C, Manary MJ. Alternative Ready-To-Use Therapeutic Food Yields Less Recovery Than the Standard for Treating Acute Malnutrition in Children From Ghana. Glob Health Sci Pract. 2019;7(2):203-214. PMID:31189698 Langlois B, Griswold S, Suri D, Shen Y, Chui K, Walton S, Manary M, Rosenberg I, Webb P, Rogers B. Comparative Effectiveness of Four Specialized Nutritious Food Products for Treatment of Moderate Acute Malnutrition in Sierra Leone (P10-140-19). Curr Dev Nutr. 2019;3(Suppl 1). PMCID:PMC6573923 PMID:31223780 Kaimila Y, Pitman RT, Divala O, Hendrixson DT, Stephenson KB, Agapova S, Trehan I, Maleta K, Manary MJ. Development of Acute Malnutrition Despite Nutritional Supplementation in Malawi. J Pediatr Gastroenterol Nutr. 2019;68(5):734-737. PMID:31022095 Pitman RT, Mui M, Michelson PH, Manary MJ. Ready-to-Use Supplemental Food for Nutritional Supplementation in Cystic Fibrosis. Curr Dev Nutr. 2019;3(5):nzz016. doi:10.1093/cdn/nzz016 PMCID:PMC6468303 PMID:31011716 Stobaugh HC, Mayberry A, McGrath M, Bahwere P, Zagre NM, Manary MJ, Black R, Lelijveld N. Relapse after severe acute malnutrition: A systematic literature review and secondary data analysis. Matern Child Nutr. 2019;15(2):e12702. PMID:30246929 Cheng WD, Wold KJ, Bollinger LB, Ordiz MI, Shulman RJ, Maleta KM, Manary MJ, Trehan I. Supplementation With Lactoferrin and Lysozyme Ameliorates Environmental Enteric Dysfunction: A Double-Blind, Randomized, Placebo-Controlled Trial. Am J Gastroenterol. 2019;114(4):671-678. doi:10.14309/ajg.0000000000000170 PMID:30829679 Kaimila Y, Divala O, Agapova SE, Stephenson KB, Thakwalakwa C, Trehan I, Manary MJ, Maleta KM. Consumption of Animal-Source Protein is Associated with Improved Height-for-Age z Scores in Rural Malawian Children Aged 12-36 Months. Nutrients. 2019;11(2):480. doi:10.3390/nu11020480 PMCID:PMC6413013 PMID:30823563 Maleta KM, Manary MJ. WASH alone cannot prevent childhood linear growth faltering. Lancet Glob Health. 2019;7(1):e16-e17. PMID:30554752 Thaxton GE, Melby PC, Manary MJ, Preidis GA. New Insights into the Pathogenesis and Treatment of Malnutrition. Gastroenterol Clin North Am. 2018;47(4):813-827. PMCID:PMC6484436 PMID:30337034 Bliss J, Lelijveld N, Briend A, Kerac M, Manary M, McGrath M, Weise Prinzo Z, Shepherd S, Marie Zagre N, Woodhead S, Guerrero S, Mayberry A. Use of Mid-Upper Arm Circumference by Novel Community Platforms to Detect, Diagnose, and Treat Severe Acute Malnutrition in Children: A Systematic Review. Glob Health Sci Pract. 2018;6(3):552-564. PMCID:PMC6172115 PMID:30185435 Ordiz MI, Wold K, Kaimila Y, Divala O, Gilstrap M, Lu HZ, Manary MJ. Detection and interpretation of fecal host mRNA in rural Malawian infants aged 6-12 months at risk for environmental enteric dysfunction. Exp Biol Med (Maywood). 2018;243(12):985-989. PMCID:PMC6180405 PMID:30099958 Ngoma TN, Chimimba UK, Mwangwela AM, Thakwalakwa C, Maleta KM, Manary MJ, Trehan I. Effect of cowpea flour processing on the chemical properties and acceptability of a novel cowpea blended maize porridge. PLoS One. 2018;13(7):e0200418. PMCID:PMC6039016 PMID:29990380 Glosz CM, Schaffner AA, Reaves SK, Manary MJ, Papathakis PC. Effect of Nutritional Interventions on Micronutrient Status in Pregnant Malawian Women with Moderate Malnutrition: A Randomized, Controlled Trial. Nutrients. 2018;10(7). PMCID:PMC6073606 PMID:29986492 Lee R, Singh L, van Liefde D, Callaghan-Gillespie M, Steiner-Asiedu M, Saalia K, Edwards C, Serena A, Hershey T, Manary MJ. Milk Powder Added to a School Meal Increases Cognitive Test Scores in Ghanaian Children. J Nutr. 2018;148(7):1177-1184. PMID:29905824 Stobaugh HC, Rogers BL, Rosenberg IH, Webb P, Maleta KM, Manary MJ, Trehan I. Children with Poor Linear Growth Are at Risk for Repeated Relapse to Wasting after Recovery from Moderate Acute Malnutrition J Nutr. 2018;148(6):974-979. doi:10.1093/jn/nxy033 PMID:29726948 May T, Klatt KC, Smith J, Castro E, Manary M, Caudill MA, Jahoor F, Fiorotto ML. Choline Supplementation Prevents a Hallmark Disturbance of Kwashiorkor in Weanling Mice Fed a Maize Vegetable Diet: Hepatic Steatosis of Undernutrition. Nutrients. 2018;10(5). doi:10.3390/nu10050653 PMCID:PMC5986532 PMID:29786674 Stobaugh HC, Rogers BL, Webb P, Rosenberg IH, Thakwalakwa C, Maleta KM, Trehan I, Manary MJ. Household-level factors associated with relapse following discharge from treatment for moderate acute malnutrition Br J Nutr. 2018;119(9):1039-1046. doi:10.1017/S0007114518000363 PMID:29502542 Ordiz MI, Davitt C, Stephenson K, Agapova S, Divala O, Shaikh N, Manary MJ. EB 2017 Article: Interpretation of the lactulose:mannitol test in rural Malawian children at risk for perturbations in intestinal permeability Exp Biol Med (Maywood). 2018;243(8):677-683. doi:10.1177/1535370218768508 PMID:29597877 Bailey J, Lelijveld N, Marron B, Onyoo P, Ho LS, Manary M, Briend A, Opondo C, Kerac M. Combined Protocol for Acute Malnutrition Study (ComPAS) in rural South Sudan and urban Kenya: study protocol for a randomized controlled trial Trials. 2018;19(1):251. doi:10.1186/s13063-018-2643-2 PMCID:PMC5978994 PMID:29690916 Janssen S, McDonald D, Gonzalez A, Navas-Molina JA, Jiang L, Xu ZZ, Winker K, Kado DM, Orwoll E, Manary M, Mirarab S, Knight R. Phylogenetic Placement of Exact Amplicon Sequences Improves Associations with Clinical Information mSystems. 2018;3(3). doi:10.1128/mSystems.00021-18 PMCID:PMC5904434 PMID:29719869 Hendrixson DT, Koroma AS, Callaghan-Gillespie M, Weber J, Papathakis P, Manary MJ. Use of a novel supplementary food and measures to control inflammation in malnourished pregnant women in Sierra Leone to improve birth outcomes: study protocol for a prospective, randomized, controlled clinical effectiveness trial. BMC Nutr. 2018;4:15. doi:10.1186/s40795-018-0218-y PMCID:PMC7050866 PMID:32153879 Agapova SE, Stephenson KB, Divala O, Kaimila Y, Maleta KM, Thakwalakwa C, Ordiz MI, Trehan I, Manary MJ. Additional Common Bean in the Diet of Malawian Children Does Not Affect Linear Growth, but Reduces Intestinal Permeability J Nutr. 2018;148(2):267-274. doi:10.1093/jn/nxx013 PMID:29490090 Stephenson KB, Agapova SE, Divala O, Kaimila Y, Maleta KM, Thakwalakwa C, Ordiz MI, Trehan I, Manary MJ. Complementary Feeding with Cowpea Reduces Growth Faltering in Rural Malawian Infants: A Blind, Randomized Controlled Clinical Trial Am J Clin Nutr. 2017;106(6):1500-1507. doi:10.3945/ajcn.117.160986 PMID:29092882 Semba RD, Trehan I, Li X, Salem N Jr, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Manary MJ. Low Serum w-3 and w-6 Polyunsaturated Fatty Acids and other metabolites Are Associated With Poor Linear Growth in Young Children from Rural Malawi Am J Clin Nutr. 2017;106(6):1490-1499. doi:10.3945/ajcn.117.164384 PMID:29070563 Cheng WD, Wold KJ, Benzoni NS, Thakwalakwa C, Maleta KM, Manary MJ, Trehan I. Lactoferrin and Lysozyme to Reduce Environmental Enteric Dysfunction and Stunting in Malawian Children: Study Protocol for a Randomized Controlled Trial Trials. 2017;18(1):523. doi:10.1186/s13063-017-2278-8 PMID:29110675 Friebert A, Callaghan-Gillespie M, Papathakis PC, Manary MJ. Adolescent Pregnancy and Nutrition: A subgroup Analysis from the Mamachiponde Study in Malawi Ann N Y Acad Sci. 2017. doi:10.1111/nyas.13465 PMID:29044558 Borresen EC, Zhang L, Trehan I, Nealon NJ, Maleta KM, Manary MJ, Ryan EP. The Nutrient and Metabolite Profile of 3 Complementary Legume Foods with Potential to Improve Gut Health in Rural Malawian Children. Curr Dev Nutr. 2017;1(10):e001610. PMCID:PMC5998778 PMID:29955682 Callaghan-Gillespie M, Schaffner AA, Garcia P, Fry J, Eckert R, Malek S, Trehan I, Thakwalakwa C, Maleta KM, Manary MJ, Papathakis PC. Trial of Ready-To-Use Supplemental Food and Corn-Soy Blend in Pregnant Malawian Women with Moderate Malnutrition: A Randomized Controlled Clinical Trial Am J Clin Nutr. 2017. doi:10.3945/ajcn.117.157198 PMID:28793991 Stobaugh HC, Bollinger LB, Adams SE, Crocker AH, Grise JB, Kennedy JA, Thakwalakwa C, Maleta KM, Dietzen DJ, Manary MJ, Trehan I. Effect of a Package of Health and Nutrition Services on Sustained Recovery in Children After Moderate Acute Malnutrition and Factors Related to Sustaining Recovery: A Cluster-Randomized Trial Am J Clin Nutr. 2017;106(2):657-666. doi:10.3945/ajcn.116.149799 PMID:28615258 Heikens GT, Manary MJ, Trehan I. African Children With Severe Pneumonia Remain at High Risk for Death Even After Discharge Paediatr Perinat Epidemiol. 2017;31(3):243-244. doi:10.1111/ppe.12350 PMID:28387423 Hu J, Klinich KD, Manary MA, Flannagan CAC, Narayanaswamy P, Reed MP, Andreen M, Neal M, Lin CH. Does unbelted safety requirement affect protection for belted occupants? Traffic Inj Prev. 2017;18(sup1):S85-S95. PMID:28296431 Manary MJ, Callaghan M. Do Vulnerable Populations Consume Adequate Amounts of Dietary Protein? J Nutr. 2017;147(5):725-726. doi:10.3925/jn.117.248252 PMID:28404831 Curran J, McLachlan M, Black R, Widdders I, Manary M. Collaboration Among Sectors to Increase Pulse Consumption Ann N Y Acad Sci. 2017;1392(1):3-5. doi:10.1111/nyas.13321 PMID:28253438 Alpers DH, Young GP, Tran CD, Mortimer EK, Gopalsamy GL, Krebs NG, Manary MJ, Ramakrishna BS, Binder HJ, Brown IL, Miller LV. Drug-Development Concepts as Guides for Optimizing Clinical Trials of Supplemental Zinc for Populations at Risk of Deficiency or Diarrhea Nutr Rev. 2017;75(3):147-162. doi:10.1093/nutrit/nuw065 PMID:28399577 Ordiz MI, Stephenson K, Agapova S, Wylie KM, Maleta K, Martin J, Trehan I, Tarr PI, Manary MJ. Environmental Enteric Dysfunction and the Fecal Microbiota in Malawian Children. Am J Trop Med Hyg. 2017;96(2):473-476. doi:10.4269/ajtmh.16-0617 PMID:27956653 Janowski AB, Krishnamurthy SR, Lim ES, Zhao G, Brenchley JM, Barouch DH, Thakwalakwa C, Manary MJ Holtz LR, Wang D. Statoviruses, A Novel Taxon of RNA Viruses Present in the Gastrointestinal Tracts of Diverse Mammals Virology. 2017;504:36-44. PMID:28152382 Ordiz MI, Stephenson K, Agapova S, Wylie KM, Maleta K, Martin J, Trehan I, Tarr PI, Manary MJ. A Combined Intervention of Zinc, Multiple Micronutrients, and Albendazole Does Not Ameliorate Environmental Enteric Dysfunction or Stunting in Rural Malawian Children in a Double-Blind Randomized Controlled Trial. J Nutr. 2017;147(1):97-103. doi:10.3945/jn.116.237735 PMID:27807040 Callaghan M, Oyama M, Manary M. Sufficient Protein Quality of Food Aid Varies with the Physiologic Status of Recipients J Nutr. 2017. doi:10.3945/jn.116.239665 PMID:28100604 Semba RD, Trehan I, Li X, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Shardell M, Ferrucci L, Manary M. Environmental Enteric Dysfunction is Associated with Carnitine Deficiency and Altered Fatty Acid Oxidation EBioMedicine. 2017. doi:10.1016/j.ebiom.2017.01.026 PMID:28122695 Di Giovanni V, Bourdon C, Wang DX, Seshadri S, Senga E, Versloot CJ, Voskuijl W, Semba RD, Trehan I, Moaddel R, Ordiz MI, Zhang L, Parkinson J, Manary MJ, Bandsma RH. Metabolomic Changes in Serum of Children with Different Clinical Diagnoses of Malnutrition. J Nutr. 2016;146(12):2436-2444. PMCID:PMC5118769 PMID:27807038 Owino V, Ahmed T, Freemark M, Kelly P, Loy A, Manary M, Loechl C. Environmental Enteric Dysfunction and Growth Failure/Stunting in Global Child Health. Pediatrics. 2016;138(6). PMID:27940670 Ordiz MI, Shaikh N, Trehan I, Maleta K, Stauber J, Shulman R, Devaraj S, Tarr PI, Manary MJ. Environmental Enteric Dysfunction is Associated With Poor Linear Growth and Can Be Identified by Host Fecal mRNAs. J Pediatr Gastroenterol Nutr. 2016;63(5):453-459. PMID:27347722 Papathakis PC, Singh LN, Manary MJ. How Maternal Malnutrition Affects Linear Growth and Development in the Offspring. Mol Cell Endocrinol. 2016;435:40-47. PMID:26820126 Bailey J, Chase R, Kerac M, Briend A, Manary MJ, Opondo C, Gallagher M, Kim A. Combined protocol for SAM/MAM treatment: The ComPAS study Field Exchange. 2016;(53):44.
Briend A, Alvarez J, Avril N, Bahwere P, Bailey J, Berkley JA, Binns P, Blackwell N, Dale N, Deconinck H, Delchevalerie P, Dent N, Gallagher M, Guerrero S, Hanson K, Kerac M, Manary MJ, Mwangome MK, Myatt M, Phelan K, Pietzsch S, Ubach NS, Shepherd S, van der Kam S, Vargas A, Whitney S. Low mid-upper arm circumference identifies children with a high risk of death who should be the priority target for treatment BMC Nutrition. 2016;63. doi:https://doi.org/10.1186/s40795-016-0101-7 Semba RD, Trehan I, Gonzalez-Freire M, Kraemer K, Moaddel R, Ordiz MI, Ferrucci L, Manary MJ. Perspective: The Potential Role of Essential Amino Acids and the Mechanistic Target of Rapamycin Complex 1 (mTORCI) Pathway in the Pathogenesis of Child Stunting Adv Nutr. 2016;7(5):853-865. PMID:27633102 Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ. Antibiotics as part of the management of severe acute malnutrition. Malawi Med J. 2016;28(3):123-130. PMCID:PMC5117002 PMID:27895846 Trehan I, Schechtman KB, Manary MJ. Amoxicillin for Severe Acute Malnutrition in Children. N Engl J Med. 2016;375(2):191. PMID:27410940 Semba RD, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Khadeer M, Ordiz MI, Ferrucci L, Manary MJ. Environmental Enteric Dysfunction is Associated with Altered Bile Acid Metabolism. J Pediatr Gastroenterol Nutr. 2016;104(1):191-197. PMID:27322559 Semba RD, Zhang P, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Ferrucci L, Manary MJ. The Association of Serum Choline With Linear Growth Failure in Young Children From Rural Malawi. Am J Clin Nutr. 2016;104(1):191-197. PMID:27281303 Trehan I, Manary MJ. An Important Chapter in the Infection-Malnutrition Story Lancet Glob Health. 2016;4(7):e430-e431. PMID:27289200 Semba RD, Shardell M, Trehan I, Moaddel R, Maleta KM, Ordiz MI, Kraemer K, Khadeer M, Ferrucci L, Manary MJ. Metabolic Alterations in Children With Environmental Enteric Dysfunction. Sci Rep. 2016;6:28009. PMCID:PMC4904796 PMID:27294788 Stauber J, Shaikh N, Ordiz MI, Tarr PI, Manary MJ. Droplet digital PCR Quantifies Host Inflammatory Transcripts in Feces Reliably and Reproducibly Cell Immunol. 2016;303:43-49. PMID:27063479 Manary M. The Paneth Cell: A Guardian of Gut Health. Cell Mol Gastroenterol Hepatol. 2016;2(3):259. PMCID:PMC5042368 PMID:28174718 Semba RD, Shardell M, Sakr Ashour FA, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Kraemer K, Khadeer MA, Ferrucci L, Manary MJ. Child Stunting is Associated with Low Circulating Essential Amino Acids. EBioMedicine. 2016;6:246-452. PMCID:PMC4856740 PMID:27211567 Rodas-Moya S, Kodish S, Manary M, Grede N, de Pee S. Preferences for food and nutritional supplements among adult people living with HIV in Malawi. Public Health Nutr. 2016;19(4):693-702. PMID:26054934 Stobaugh HC, Ryan KN, Kennedy JA, Grise JB, Crocker AH, Thakwalakwa C, Litkowski PE, Maleta KM, Manary MJ, Trehan I. Including Whey Protein and Whey Permeate in Ready-To-Use Supplementary Food Improves Recovery Rates in Children With Moderate Acute Malnutrition: A Randomized, Double-Blind Clinical Trial. Am J Clin Nutr. 2016;103(3):926-933. doi:10.3945/ajcn.115.124636 PMID:26864368 Trehan I, Kelly P, Shaikh N, Manary MJ. New Insights Into Environmental Enteric Dysfunction. Arch Dis Child. 2016;101(8):741-744. PMID:26933151 Manary M, Callaghan M, Singh L, Briend A. Protein Quality and Growth in Malnourished Children Food Nutr Bull. 2016;37 Suppl 1:S29-S36. PMID:26857118 Blanton LV, Charbonneau MR, Salih T, Barratt MJ, Venkatesh S, Ilkaveya O, Subramanian S, Manary MJ, Trehan I, Jorgensen JM, Fan YM, Henrissat B, Leyn SA, Rodionov DA, Osterman AL, Maleta KM, Newgard CB, Ashorn P, Dewey KG, Gordon JI. Gut Bacteria That Prevent Growth Impairments Transmitted by Microbiota from Malnourished Children. Science. 2016;351(6275). PMCID:PMC4787260 PMID:26912898 Yu J, Ordiz MI, Stauber J, Shaikh N, Trehan I, Barnell E, Head RD, Maleta K, Tarr PI, Manary MJ. Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair Processes. Cell Mol Gastroenterol Hepatol. 2016;2(2):158-174.e1. doi:10.1016/j.jcmgh.2015.12.002 PMCID:PMC4769221 PMID:26973864 Weber JM, Ryan KN, Tandon R, Mathur M, Girma T, Steiner-Asiedu M, Saalia F, Zaidi S, Soofi S, Okos M, Vosti SA, Manary MJ. Acceptability of locally produced ready-to-use therapeutic foods in Ethiopia, Ghana, Pakistan and India. Matern Child Nutr. 2016. doi:10.1111/mcn.12250 PMID:26776270 Moodley-Govender E, Mulol H, Stauber J, Manary M, Coutsoudis A. Increased Exclusivity of Breastfeeding Associated with Reduced Gut Inflammation in Infants. Breastfeed Med. 2015;10:488-492. doi:10.1089/bfm.2015.0110 PMID:26594906 Mangani C, Maleta K, Phuka J, Cheung YB, Thakwalakwa C, Dewey K, Manary M, Puumalainen T, Ashorn P. Effect of complementary feeding with lipid-based nutrient supplements and corn-soy blend on the incidence of stunting and linear growth among 6- to 18-month-old infants and children in rural Malawi. Matern Child Nutr. 2015;11 Suppl 4:132-43. PMID:23795976 Trehan I, Benzoni NS, Wang AZ, Bollinger LB, Ngoma TN, Chimimba UK, Stephenson KB, Agapova SE, Maleta KM, Manary MJ. Common beans and cowpeas as complementary foods to reduce environmental enteric dysfunction and stunting in Malawian children: study protocol for two randomized controlled trials. Trials. 2015;16(1):520. doi:10.1186/s13063-015-1027-0 PMCID:PMC4650393 PMID:26578308 Maust A, Koroma AS, Abla C, Molokwu N, Ryan KN, Singh L, Manary MJ. Severe and Moderate Acute Malnutrition Can Be Successfully Managed with an Integrated Protocol in Sierra Leone. J Nutr. 2015;145(11):2604-2609. doi:10.3945/jn.115.214957 PMID:26423737 Reyes A, Blanton LV, Cao S, Zhao G, Manary M, Trehan I, Smith MI, Wang D, Virgin HW, Rohwer F, Gordon JI. Gut DNA viromes of Malawian twins discordant for severe acute malnutrition. Proc Natl Acad Sci U S A. 2015;112(38):11941-11946. doi:10.1073/pnas.1514285112 PMCID:PMC4586842 PMID:26351661 Ordiz MI, May TD, Mihindukulasuriya K, Martin J, Crowley J, Tarr PI, Ryan K, Mortimer E, Gopalsamy G, Maleta K, Mitreva M, Young G, Manary MJ. The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children. Microbiome. 2015;3:37. doi:10.1186/s40168-015-0102-9 PMCID:PMC4558878 PMID:26334878 Ordiz MI, Ryan KN, Cimo ED, Stoner ME, Loehnig ME, Manary MJ. Effect of emulsifier and viscosity on oil separation in ready-to-use therapeutic food. Int J Food Sci Nutr. 2015;66(6):642-648. doi:10.3109/09637486.2015.1077784 PMID:26299733 Hsieh JC, Liu L, Zeilani M, Ickes S, Trehan I, Maleta K, Craig C, Thakwalakwa C, Singh L, Brenna JT, Manary MJ. High-Oleic Ready-to-Use Therapeutic Food Maintains Docosahexaenoic Acid Status in Severe Malnutrition. J Pediatr Gastroenterol Nutr. 2015;61(1):138-143. doi:10.1097/MPG.0000000000000741 PMCID:PMC4483140 PMID:25633498 Benzoni N, Korpe P, Thakwalakwa C, Maleta K, Stephenson K, Manary M, Manary M. Plasma Endotoxin Core Antibody Concentration and Linear Growth are Unrelated in Rural Malawian Children Aged 2-5 Years. BMC Res Notes. 2015;8:258. doi:10.1186/s13104-015-1238-1 PMCID:PMC4477295 PMID:26103960 Brenna JT, Akomo P, Bahwere P, Berkley JA, Calder PC, Jones KD, Liu L, Manary M, Trehan I, Briend A. Balancing Omega-6 and Omega-3 Fatty Acids in Ready-To-Use Therapeutic Foods (RUTF). BMC Med. 2015;13:117. doi:10.1186/s12916-015-0352-1 PMCID:PMC4433071 PMID:25980919 Manary M. It's the context! Am J Clin Nutr. 2015;101(4):693-4. PMID:25739928 Iannotti LL, Trehan I, Clitheroe KL, Manary MJ. Diagnosis and treatment of severely malnourished children with diarrhoea. J Paediatr Child Health. 2015;51(4):387-395. doi:10.1111/jpc.12711 PMID:25196813 May T, Westcott C, Thakwalakwa C, Ordiz MI, Maleta K, Westcott J, Ryan K, Hambidge KM, Miller LV, Young G, Mortimer E, Manary MJ, Krebs NF. Resistant starch does not affect zinc homeostasis in rural Malawian children. J Trace Elem Med Biol. 2015;30:43-48. doi:10.1016/j.jtemb.2015.01.005 PMID:25744509 Trehan I, Banerjee S, Murray E, Ryan KN, Thakwalakwa C, Maleta KM, Manary MJ. Extending supplementary feeding for children younger than 5 years with moderate acute malnutrition leads to lower relapse rates. J Pediatr Gastroenterol Nutr. 2015;60(4):544-549. doi:10.1097/MPG.0000000000000639 PMCID:PMC4380557 PMID:25419681 Osendarp S, Rogers B, Ryan K, Manary M, Akomo P, Bahwere P, Belete H, Zeilani M, Islam M, Dibari F, De Pee S. Ready-to-use foods for management of moderate acute malnutrition: considerations for scaling up production and use in programs. Food Nutr Bull. 2015;36(1 Suppl):S59-S64. PMID:25902616 Murray E, Manary M. Possible role of the microbiome in the development of acute malnutrition and implications for food-based strategies to prevent and treat acute malnutrition. Food Nutr Bull. 2015;36(1 Suppl):S72-S75. PMID:25902618 Briend A, Akomo P, Bahwere P, De Pee S, Dibari F, Golden MH, Manary M, Ryan K. Developing food supplements for moderately malnourished children: lessons learned from ready-to-use therapeutic foods. Food Nutr Bull. 2015;36(1 Suppl):S53-S58. PMID:25902615 Kau AL, Planer JD, Liu J, Rao S, Yatsunenko T, Trehan I, Manary MJ, Liu TC, Stappenbeck TS, Maleta KM, Ashorn P, Dewey KG, Houpt ER, Hsieh CS, Gordon JI. Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy. Sci Transl Med. 2015;7(276):276ra24. doi:10.1126/scitranslmed.aaa4877 PMCID:PMC4423598 PMID:25717097 Gopalsamy GL, Alpers DH, Binder HJ, Tran CD, Ramakrishna BS, Brown I, Manary M, Mortimer E, Young GP. The relevance of the colon to zinc nutrition. Nutrients. 2015;7(1):572-83. PMCID:PMC4303854 PMID:25594440 Ryan KN, Adams KP, Vosti SA, Ordiz MI, Cimo ED, Manary MJ. A comprehensive linear programming tool to optimize formulations of ready-to-use therapeutic foods: an application to Ethiopia. Am J Clin Nutr. 2014;100(6):1551-1558. doi:10.3945/ajcn.114.090670 PMID:25411290 Smith HE, Ryan KN, Stephenson KB, Westcott C, Thakwalakwa C, Maleta K, Cheng JY, Brenna JT, Shulman RJ, Trehan I, Manary MJ. Multiple micronutrient supplementation transiently ameliorates environmental enteropathy in Malawian children aged 12-35 months in a randomized controlled clinical trial. J Nutr. 2014;144(12):2059-2065. doi:10.3945/jn.114.201673 PMID:25411039 Mangani C, Ashorn P, Maleta K, Phuka J, Thakwalakwa C, Dewey K, Manary M, Puumalainen T, Cheung YB. Lipid-based nutrient supplements do not affect the risk of malaria or respiratory morbidity in 6- to 18-month-old Malawian children in a randomized controlled trial. J Nutr. 2014;144(11):1835-42. PMID:25332483 Young GP, Mortimer EK, Gopalsamy GL, Alpers DH, Binder HJ, Manary MJ, Ramakrishna BS, Brown IL, Brewer TG. Zinc deficiency in children with environmental enteropathy-development of new strategies: report from an expert workshop. Am J Clin Nutr. 2014;100(4):1198-1207. doi:10.3945/ajcn.113.075036 PMCID:PMC4163797 PMID:25240082 Ryan KN, Stephenson KB, Trehan I, Shulman RJ, Thakwalakwa C, Murray E, Maleta K, Manary MJ. Zinc or albendazole attenuates the progression of environmental enteropathy: a randomized controlled trial. Clin Gastroenterol Hepatol. 2014;12(9):1507-1513.e1. doi:10.1016/j.cgh.2014.01.024 PMID:24462483 Thakwalakwa C, Phiri A, Rollins N, Heikens GT, Barnell EK, Manary M. Growth and HIV-free survival of HIV-exposed infants in Malawi: a randomized trial of two complementary feeding interventions in the context of maternal antiretroviral therapy. J Acquir Immune Defic Syndr. 2014;66(2):181-187. doi:10.1097/QAI.0000000000000150 PMID:24662296 Mangani C, Cheung YB, Maleta K, Phuka J, Thakwalakwa C, Dewey K, Manary M, Puumalainen T, Ashorn P. Providing lipid-based nutrient supplements does not affect developmental milestones among Malawian children. Acta Paediatr. 2014;103(1):e17-26. doi:10.1111/apa.12443 PMID:24118040 Briend A, Collins S, Golden M, Manary M, Myatt M. Maternal and child nutrition. Lancet. 2013;382(9904):1549. PMID:24209819 Iannotti LL, Trehan I, Manary MJ. Review of the safety and efficacy of vitamin A supplementation in the treatment of children with severe acute malnutrition. Nutr J. 2013;12:125-139. doi:10.1186/1475-2891-12-125 PMCID:PMC3850897 PMID:24028603 Trehan I, Maleta KM, Manary MJ. Antibiotics for uncomplicated severe malnutrition. N Engl J Med. 2013;368(25):2436-2437. doi:10.1056/NEJMc1304407 PMID:23782188 Manary M. Inadequate dietary protein intake: when does it occur and what are the consequences? Food Nutr Bull. 2013;34(2):247-8. PMID:23964402 Manary M. Protein source and quality in therapeutic foods affect the immune response and outcome in severe acute malnutrition. Food Nutr Bull. 2013;34(2):256-8. PMID:23964405 Lim ES, Reyes A, Antonio M, Saha D, Ikumapayi UN, Adeyemi M, Stine OC, Skelton R, Brennan DC, Mkakosya RS, Manary MJ, Gordon JI, Wang D. Discovery of STL polyomavirus, a polyomavirus of ancestral recombinant origin that encodes a unique T antigen by alternative splicing. Virology. 2013;436(2):295-303. doi:10.1016/j.virol.2012.12.005 PMCID:PMC3693558 PMID:23276405 Chang CY, Trehan I, Wang RJ, Thakwalakwa C, Maleta K, Deitchler M, Manary MJ. Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery. J Nutr. 2013;143(2):215-220. doi:10.3945/jn.112.168047 PMID:23256140 Smith MI, Yatsunenko T, Manary MJ, Trehan I, Mkakosya R, Cheng J, Kau AL, Rich SS, Concannon P, Mychaleckyj JC, Liu J, Houpt E, Li JV, Holmes E, Nicholson J, Knights D, Ursell LK, Knight R, Gordon JI. Gut microbiomes of Malawian twin pairs discordant for kwashiorkor. Science. 2013;339(6119):548-554. doi:10.1126/science.1229000 PMCID:PMC3667500 PMID:23363771 Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ. Antibiotics as part of the management of severe acute malnutrition. N Engl J Med. 2013;368(5):425-435. doi:10.1056/NEJMoa1202851 PMCID:PMC3654668 PMID:23363496 Wang RJ, Trehan I, LaGrone LN, Weisz AJ, Thakwalakwa CM, Maleta KM, Manary MJ. Investigation of food acceptability and feeding practices for lipid nutrient supplements and blended flours used to treat moderate malnutrition. J Nutr Educ Behav. 2013;45(3):258-263. doi:10.1016/j.jneb.2012.08.001 PMCID:PMC3644177 PMID:23246175 Agapova S, Stephenson K, Manary M, Weisz A, Tarr PI, Mkakosya R, Maleta K, Shulman RJ, Manary M, Shaikh N. Detection of low-concentration host mRNA transcripts in Malawian children at risk for environmental enteropathy. J Pediatr Gastroenterol Nutr. 2013;56(1):66-71. doi:10.1097/MPG.0b013e31826a107a PMID:22832511 Murray E, Manary MJ. Dairy components in therapeutic foods for malnutrition result in improved clinical outcomes Bulletin of the International Dairy Federation. 2013;(463):45-48.
Weisz AJ, Manary MJ, Stephenson K, Agapova S, Manary FG, Thakwalakwa C, Shulman RJ, Manary MJ. Abnormal gut integrity is associated with reduced linear growth in rural Malawian children. J Pediatr Gastroenterol Nutr. 2012;55(6):747-750. doi:10.1097/MPG.0b013e3182650a4d PMID:22732897 Siebrasse EA, Reyes A, Lim ES, Zhao G, Mkakosya RS, Manary MJ, Gordon JI, Wang D. Identification of MW polyomavirus, a novel polyomavirus in human stool. J Virol. 2012;86(19):10321-10326. doi:10.1128/JVI.01210-12 PMCID:PMC3457274 PMID:22740408 Pond CD, Mant A, Bridges-Webb C, Purcell C, Eyland EA, Hewitt H, Saunders NA. Recognition of depression in the elderly: a comparison of general practitioner opinions and the Geriatric Depression Scale. J Agricultural Food Chemistry. 2012;60:3861-3866. PMID:2245889 Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Baldassano RN, Anokhin AP, Heath AC, Warner B, Reeder J, Kuczynski J, Caporaso JG, Lozupone CA, Lauber C, Clemente JC, Knights D, Knight R, Gordon JI. Human gut microbiome viewed across age and geography. Nature. 2012;486(7402):222-227. doi:10.1038/nature11053 PMCID:PMC3376388 PMID:22699611 Failla ML, Chitchumroonchokchai C, Siritunga D, De Moura FF, Fregene M, Manary MJ, Sayre RT. Retention during processing and bioaccessibility of β-carotene in high β-carotene transgenic cassava root. J Agric Food Chem. 2012;60(15):3861-6. PMID:22458891 Li X, Yang J, Manary MJ, Hirschi KD. Biotechnologically-modified cassava: Protein absorption relative to casein Bioequivalence and Bioavailability. 2012;4(4):40-43.
Phuka JC, Gladstone M, Maleta K, Thakwalakwa C, Cheung YB, Briend A, Manary MJ, Ashorn P. Developmental outcomes among 18-month-old Malawians after a year of complementary feeding with lipid-based nutrient supplements or corn-soy flour. Matern Child Nutr. 2012;8(2):239-248. doi:10.1111/j.1740-8709.2011.00294.x PMID:21342456 Manary MJ, Trehan I, Willumsen J. Systematic review of the care of HIV-infected children with severe acute malnutrition Geneva: World Health Organization. 2012.
Manary MJ, Trehan I. Systematic review of the role of fluid infusions and blood transfusions in the care of hospitalized children with severe acute malnutrition Geneva: World Health Organization. 2012.
Kerac M, Trehan I, Weisz A, Agapova S, Manary MJ. Admission and discharge criteria for the management of severe acute malnutrition in infants aged under 6 months Geneva: World Health Organization. 2012.
Manary MJ, Trehan I, Weisz A. Systematic review of transition phase feeding of children with severe acute malnutrition as inpatients Geneva: World Health Organization. 2012.
Manary MJ, Iannotti LL, Trehan I. Systematic review of vitamin A supplementation in the treatment of children with severe acute malnutrition Geneva: World Health Organization. 2012.
Kim MH, Cox C, Dave A, Draper HR, Kabue M, Schutze GE, Ahmed S, Kazembe PN, Kline MW, Manary M. Prompt initiation of ART With therapeutic food is associated with improved outcomes in HIV-infected Malawian children with malnutrition. J Acquir Immune Defic Syndr. 2012;59(2):173-176. doi:10.1097/QAI.0b013e3182405f8f PMID:22107819 Manary MJ, Iannotti L, Trehan I, Weisz A. Systematic review of the care of children with diarrhoea in the community-based management of severe acute malnutrition Geneva: World Health Organization. 2012.
LaGrone LN, Trehan I, Meuli GJ, Wang RJ, Thakwalakwa C, Maleta K, Manary MJ. A novel fortified blended flour, corn-soy blend "plus-plus," is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children. Am J Clin Nutr. 2012;95(1):212-219. doi:10.3945/ajcn.111.022525 PMCID:PMC3238461 PMID:22170366 Connor NE, Manary MJ, Maleta K. Monitoring the adequacy of catch-up growth among moderately malnourished children receiving home-based therapy using mid-upper arm circumference in southern Malawi. Matern Child Health J. 2011;15(7):980-4. PMID:20082126 Phuka J, Ashorn U, Ashorn P, Zeilani M, Cheung YB, Dewey KG, Manary M, Maleta K. Acceptability of three novel lipid-based nutrient supplements among Malawian infants and their caregivers. Matern Child Nutr. 2011;7(4):368-377. doi:10.1111/j.1740-8709.2011.00297.x PMID:21518250 Weisz A, Meuli G, Thakwalakwa C, Trehan I, Maleta K, Manary M. The duration of diarrhea and fever is associated with growth faltering in rural Malawian children aged 6-18 months. Nutr J. 2011;10(1):25-29. doi:10.1186/1475-2891-10-25 PMCID:PMC3068082 PMID:21418600 de Pee S, Manary M, Ashorn P. The devil is in the details. Nutr Rev. 2011;69(2):116-7; author reply 118. PMID:21294745 Sayre R, Beeching JR, Cahoon EB, Egesi C, Fauquet C, Fellman J, Fregene M, Gruissem W, Mallowa S, Manary M, Maziya-Dixon B, Mbanaso A, Schachtman DP, Siritunga D, Taylor N, Vanderschuren H, Zhang P. The BioCassava plus program: biofortification of cassava for sub-Saharan Africa. Annu Rev Plant Biol. 2011;62:251-272. doi:10.1146/annurev-arplant-042110-103751 PMID:21526968 Nguema A, Norton G, Fregene M, Sayre R, Manary MJ. Expected economic benefits of meeting nutritional needs through biofortified cassava in Nigeria and Kenya African Journal of Agricultural and Resource Economics. 2011;6. doi:DOI: 10.22004/ag.econ.156956 Schneider LW, Manary MA. Transportation safety for children with special healthcare needs. J Pediatr Rehabil Med. 2011;4(4):239-40. PMID:22430619 Waterland RA, Kellermayer R, Laritsky E, Rayco-Solon P, Harris RA, Travisano M, Zhang W, Torskaya MS, Zhang J, Shen L, Manary MJ, Prentice AM. Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet. 2010;6(12):e1001252. doi:10.1371/journal.pgen.1001252 PMCID:PMC3009670 PMID:21203497 Oakley E, Reinking J, Sandige H, Trehan I, Kennedy G, Maleta K, Manary M. A ready-to-use therapeutic food containing 10% milk is less effective than one with 25% milk in the treatment of severely malnourished children. J Nutr. 2010;140(12):2248-2252. doi:10.3945/jn.110.123828 PMCID:PMC2981006 PMID:20980648 Kennedy G, Hambidge KM, Manary M. A reduced phytate diet does not reduce endogenous fecal zinc in children on a habitual high-phytate diet. J Pediatr Gastroenterol Nutr. 2010;51(5):678-679. doi:10.1097/MPG.0b013e3181e536f7 PMID:20818269 Trehan I, Amthor RE, Maleta K, Manary MJ. Evaluation of the routine use of amoxicillin as part of the home-based treatment of severe acute malnutrition. Trop Med Int Health. 2010;15(9):1022-1028. doi:10.1111/j.1365-3156.2010.02580.x PMCID:PMC2962695 PMID:20545919 Manary MJ, Abrams SA, Griffin IJ, Quimper MM, Shulman RJ, Hamzo MG, Chen Z, Maleta K, Manary MJ. Perturbed zinc homeostasis in rural 3-5-y-old Malawian children is associated with abnormalities in intestinal permeability attributed to tropical enteropathy. Pediatr Res. 2010;67(6):671-675. doi:10.1203/PDR.0b013e3181da44dc PMID:20496476 Manary M, Ndekhat M, van Oosterhout JJ. Supplementary feeding in the care of the wasted HIV infected patient. Malawi Med J. 2010;22(2):46-48. PMCID:PMC3345755 PMID:21614881 van Oosterhout JJ, Ndekha M, Moore E, Kumwenda JJ, Zijlstra EE, Manary M. The benefit of supplementary feeding for wasted Malawian adults initiating ART. AIDS Care. 2010;22(6):737-742. doi:10.1080/09540120903373581 PMID:20467944 Gegios A, Amthor R, Maziya-Dixon B, Egesi C, Mallowa S, Nungo R, Gichuki S, Mbanaso A, Manary MJ. Children consuming cassava as a staple food are at risk for inadequate zinc, iron, and vitamin A intake. Plant Foods Hum Nutr. 2010;65(1):64-70. doi:10.1007/s11130-010-0157-5 PMCID:PMC2840668 PMID:20165984 Stephenson K, Amthor R, Mallowa S, Nungo R, Maziya-Dixon B, Gichuki S, Mbanaso A, Manary M. Consuming cassava as a staple food places children 2-5 years old at risk for inadequate protein intake, an observational study in Kenya and Nigeria. Nutr J. 2010;9:9. doi:10.1186/1475-2891-9-9 PMCID:PMC2837613 PMID:20187960 Lagrone L, Cole S, Schondelmeyer A, Maleta K, Manary MJ. Locally produced ready-to-use supplementary food is an effective treatment of moderate acute malnutrition in an operational setting. Ann Trop Paediatr. 2010;30(2):103-108. doi:10.1179/146532810X12703901870651 PMID:20522296 Heikens GT, Manary M. 75 years of Kwashiorkor in Africa. Malawi Med J. 2009;21(3):96-8. PMCID:PMC3717488 PMID:20345016 Heikens GT, Manary M, Sandige H. Child survival in sub Sahara Africa: the role of CAPGAN and regional child health practitioners & scientists. Malawi Med J. 2009;21(3):94-5. PMCID:PMC3717487 PMID:20345015 Ndekha M, van Oosterhout JJ, Saloojee H, Pettifor J, Manary M. Nutritional status of Malawian adults on antiretroviral therapy 1 year after supplementary feeding in the first 3 months of therapy. Trop Med Int Health. 2009;14(9):1059-63. PMID:19552659 Heikens GT, Manary M. Wasting disease in African children: the challenges ahead. Malawi Med J. 2009;21(3):101-5. PMCID:PMC3717489 PMID:20345017 Trehan I, Shulman RJ, Ou CN, Maleta K, Manary MJ. A randomized, double-blind, placebo-controlled trial of rifaximin, a nonabsorbable antibiotic, in the treatment of tropical enteropathy. Am J Gastroenterol. 2009;104(9):2326-2333. doi:10.1038/ajg.2009.270 PMCID:PMC2758482 PMID:19491826 Manary MJ, Heikens GT, Golden M. Kwashiorkor: more hypothesis testing is needed to understand the aetiology of oedema. Malawi Med J. 2009;21(3):106-107. PMCID:PMC3717490 PMID:20345018 Ndekha MJ, van Oosterhout JJ, Zijlstra EE, Manary M, Saloojee H, Manary MJ. Supplementary feeding with either ready-to-use fortified spread or corn-soy blend in wasted adults starting antiretroviral therapy in Malawi: randomised, investigator blinded, controlled trial. BMJ. 2009;338:b1867. PMCID:PMC2685879 PMID:19465470 Phuka J, Thakwalakwa C, Maleta K, Cheung YB, Briend A, Manary M, Ashorn P. Supplementary feeding with fortified spread among moderately underweight 6-18-month-old rural Malawian children. Matern Child Nutr. 2009;5(2):159-70. PMID:19292750 Matilsky DK, Maleta K, Castleman T, Manary MJ. Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children. J Nutr. 2009;139(4):773-778. doi:10.3945/jn.108.104018 PMCID:PMC3151028 PMID:19225128 Amthor RE, Cole SM, Manary MJ. The use of home-based therapy with ready-to-use therapeutic food to treat malnutrition in a rural area during a food crisis. J Am Diet Assoc. 2009;109(3):464-467. doi:10.1016/j.jada.2008.11.028 PMID:19248863 Ashorn P, Phuka JC, Maleta K, Thakwalakwa C, Cheung YB, Briend A, Manary MJ. Undernutrition malnutrition in infants in developing countries. Arch Pediatr Adolesc Med. 2009;163(2):186. PMID:19188655 Phuka JC, Maleta K, Thakwalakwa C, Cheung YB, Briend A, Manary MJ, Ashorn P. Postintervention growth of Malawian children who received 12-mo dietary complementation with a lipid-based nutrient supplement or maize-soy flour. Am J Clin Nutr. 2009;89(1):382-90. doi:10.3945/ajcn.2008.26483 PMID:19056572 Flax VL, Maleta K, Ashorn U, Manary MJ, Briend A, Ashorn P. Intake of lipid-based nutrient supplements during illness and convalescence among moderately-underweight Malawian children. J Health Popul Nutr. 2008;26(4):468-70. PMCID:PMC2740690 PMID:19069627 Manary MJ, Sandige HL. Management of acute moderate and severe childhood malnutrition. BMJ. 2008;337:a2180. PMID:19008271 Colbourn J, Heath N, Manary S, Pacifico D. Effectiveness of splinting for the treatment of trigger finger. J Hand Ther. 2008;21(4):336-43. PMID:19006759 Miller TL, Agostoni C, Duggan C, Guarino A, Manary M, Velasco CA, HIV Working Group.. Gastrointestinal and nutritional complications of human immunodeficiency virus infection. J Pediatr Gastroenterol Nutr. 2008;47(2):247-53. PMCID:PMC4627636 PMID:18664883 Phuka JC, Maleta K, Thakwalakwa C, Cheung YB, Briend A, Manary MJ, Ashorn P. Complementary feeding with fortified spread and incidence of severe stunting in 6- to 18-month-old rural Malawians. Arch Pediatr Adolesc Med. 2008;162(7):619-626. doi:10.1001/archpedi.162.7.619 PMCID:PMC3721756 PMID:18606932 Heikens GT, Bunn J, Amadi B, Manary M, Chhagan M, Berkley JA, Rollins N, Kelly P, Adamczick C, Maitland K, Tomkins A, Blantyre Working Group. Case management of HIV-infected severely malnourished children: challenges in the area of highest prevalence. Lancet. 2008;371(9620):1305-1307. doi:10.1016/S0140-6736(08)60565-6 PMID:18406865 Lin CA, Manary MJ, Maleta K, Briend A, Ashorn P. An energy-dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6-18 months. J Nutr. 2008;138(3):593-8. doi:10.1093/jn/138.3.593 PMID:18287372 Heikens GT, Amadi BC, Manary M, Rollins N, Tomkins A. Nutrition interventions need improved operational capacity. Lancet. 2008;371(9608):181-182. doi:10.1016/S0140-6736(07)61691-2 PMID:18207567 Flax VL, Ashorn U, Phuka J, Maleta K, Manary MJ, Ashorn P. Feeding patterns of underweight children in rural Malawi given supplementary fortified spread at home. Matern Child Nutr. 2008;4(1):65-73. doi:10.1111/j.1740-8709.2007.00098.x PMID:18171408 Galpin L, Thakwalakwa C, Phuka J, Ashorn P, Maleta K, Wong WW, Manary MJ. Breast milk intake is not reduced more by the introduction of energy dense complementary food than by typical infant porridge. J Nutr. 2007;137(7):1828-1833. PMID:17585038 Linneman Z, Matilsky D, Ndekha M, Manary MJ, Maleta K, Manary MJ. A large-scale operational study of home-based therapy with ready-to-use therapeutic food in childhood malnutrition in Malawi. Matern Child Nutr. 2007;3(3):206-215. doi:10.1111/j.1740-8709.2007.00095.x PMID:17539889 Lin CA, Boslaugh S, Ciliberto HM, Maleta K, Ashorn P, Briend A, Manary MJ. A prospective assessment of food and nutrient intake in a population of Malawian children at risk for kwashiorkor. J Pediatr Gastroenterol Nutr. 2007;44(4):487-493. doi:10.1097/MPG.0b013e31802c6e57 PMID:17414147 Kuusipalo H, Maleta K, Briend A, Manary M, Ashorn P. Growth and change in blood haemoglobin concentration among underweight Malawian infants receiving fortified spreads for 12 weeks: a preliminary trial. J Pediatr Gastroenterol Nutr. 2006;43(4):525-532. doi:10.1097/01.mpg.0000235981.26700.d3 PMID:17033530 Manary MJ. Local production and provision of ready-to-use therapeutic food (RUTF) spread for the treatment of severe childhood malnutrition. Food Nutr Bull. 2006;27(3 Suppl):S83-S89. PMID:17076214 Ciliberto MA, Manary MJ, Ndekha MJ, Briend A, Ashorn P. Home-based therapy for oedematous malnutrition with ready-to-use therapeutic food. Acta Paediatr. 2006;95(8):1012-1015. doi:10.1080/08035250600606803 PMID:16882579 Manary MJ, Muglia LJ, Vogt SK, Yarasheski KE. Cortisol and its action on the glucocorticoid receptor in malnutrition and acute infection. Metabolism. 2006;55(4):550-554. doi:10.1016/j.metabol.2005.11.009 PMID:16546487 Sullivan J, Ndekha M, Maker D, Hotz C, Manary MJ. The quality of the diet in Malawian children with kwashiorkor and marasmus. Matern Child Nutr. 2006;2(2):114-122. doi:10.1111/j.1740-8709.2006.00053.x PMID:16881921 Patel MP, Sandige HL, Ndekha MJ, Briend A, Ashorn P, Manary MJ. Supplemental feeding with ready-to-use therapeutic food in Malawian children at risk of malnutrition. J Health Popul Nutr. 2005;23(4):351-357. PMID:16599106 Galpin L, Manary MJ, Fleming K, Ou CN, Ashorn P, Shulman RJ. Effect of Lactobacillus GG on intestinal integrity in Malawian children at risk of tropical enteropathy. Am J Clin Nutr. 2005;82(5):1040-1045. PMID:16280436 Ciliberto H, Ciliberto M, Briend A, Ashorn P, Bier D, Manary M. Antioxidant supplementation for the prevention of kwashiorkor in Malawian children: randomised, double blind, placebo controlled trial. BMJ. 2005;330(7500):1109-1112. doi:10.1136/bmj.38427.404259.8F PMCID:PMC557886 PMID:15851401 Ciliberto MA, Sandige H, Ndekha MJ, Ashorn P, Briend A, Ciliberto HM, Manary MJ. Comparison of home-based therapy with ready-to-use therapeutic food with standard therapy in the treatment of malnourished Malawian children: a controlled, clinical effectiveness trial. Am J Clin Nutr. 2005;81(4):864-870. PMID:15817865 Ndekha MJ, Manary MJ, Ashorn P, Briend A. Home-based therapy with ready-to-use therapeutic food is of benefit to malnourished, HIV-infected Malawian children. Acta Paediatr. 2005;94(2):222-225. PMID:15981758 Manary MJ, Yarasheski KE, Smith S, Abrams ET, Hart CA. Protein quantity, not protein quality, accelerates whole-body leucine kinetics and the acute-phase response during acute infection in marasmic Malawian children. Br J Nutr. 2004;92(4):589-95. PMID:15522127 Sandige H, Ndekha MJ, Briend A, Ashorn P, Manary MJ. Home-based treatment of malnourished Malawian children with locally produced or imported ready-to-use food. J Pediatr Gastroenterol Nutr. 2004;39(2):141-146. PMID:15269617 Manary MJ, Ndkeha MJ, Ashorn P, Maleta K, Briend A. Home based therapy for severe malnutrition with ready-to-use food. Arch Dis Child. 2004;89(6):557-561. PMCID:PMC1719944 PMID:15155403 Manary MJ, Yarasheski KE, Berger R, Abrams ET, Hart CA, Broadhead RL. Whole-body leucine kinetics and the acute phase response during acute infection in marasmic Malawian children. Pediatr Res. 2004;55(6):940-946. doi:10.1203/01.pdr.0000127017.44938.6d PMID:15155863 Maleta K, Kuittinen J, Duggan MB, Briend A, Manary M, Wales J, Kulmala T, Ashorn P. Supplementary feeding of underweight, stunted Malawian children with a ready-to-use food. J Pediatr Gastroenterol Nutr. 2004;38(2):152-158. PMID:14734876 Manary MJ, Yarasheski KE, Berger R, Broadhead RL. CO2 production during acute infection in malnourished Malawian children. Eur J Clin Nutr. 2004;58(1):116-120. doi:10.1038/sj.ejcn.1601757 PMID:14679376 Manary MJ, Yarasheski KE, Broadhead RL. Urea production and leucine oxidation in malnourished children with and without acute infection. Metabolism. 2002;51(11):1418-1422. PMID:12404191 Manary MJ, Hotz C, Krebs NF, Gibson RS, Westcott JE, Broadhead RL, Hambidge KM. Zinc homeostasis in Malawian children consuming a high-phytate, maize-based diet. Am J Clin Nutr. 2002;75(6):1057-1061. PMID:12036813 Manary MJ, Krebs NF, Gibson RS, Broadhead RL, Hambidge KM. Community-based dietary phytate reduction and its effect on iron status in Malawian children. Ann Trop Paediatr. 2002;22(2):133-136. doi:10.1179/027249302125000850 PMID:12070948 Manary M. Doctors who go the extra mile. Fighting hunger and death half a world away. Interview by Robert Lowes. Med Econ. 2002;79(3):43. PMID:11859787 Manary MJ, MacPherson GD, Mcardle F, Jackson MJ, Hart CA. Selenium status, kwashiorkor and congestive heart failure. Acta Paediatr. 2001;90(8):950-952. PMID:11529549 Manary MJ. Protein-energy malnutrition: there is still work to do. J Pediatr Gastroenterol Nutr. 2001;32(5):519-20. PMID:11429508 Manary MJ, Hotz C, Krebs NF, Gibson RS, Westcott JE, Arnold T, Broadhead RL, Hambidge KM. Dietary phytate reduction improves zinc absorption in Malawian children recovering from tuberculosis but not in well children. J Nutr. 2000;130(12):2959-2964. PMID:11110854 Manary MJ, Leeuwenburgh C, Heinecke JW. Increased oxidative stress in kwashiorkor. J Pediatr. 2000;137(3):421-424. doi:10.1067/mpd.2000.107512 PMID:10969271 Manary MJ, Brewster DR. Intensive nursing care of kwashiorkor in Malawi. Acta Paediatr. 2000;89(2):203-7. PMID:10709892 Manary MJ, Yarasheski KE, Hart CA, Broadhead RL. Plasma urea appearance rate is lower when children with kwashiorkor and infection are fed egg white-tryptophan rather than milk protein. J Nutr. 2000;130(2):183-188. PMID:10720167 Mulholland EK, Ogunlesi OO, Adegbola RA, Weber M, Sam BE, Palmer A, Manary MJ, Secka O, Aidoo M, Hazlett D, Whittle H, Greenwood BM. Etiology of serious infections in young Gambian infants. Pediatr Infect Dis J. 1999;18(10 Suppl):S35-S41. PMID:10530572 The WHO Young Infants Study Group* (Manary MJ). Clinical prediction of serious bacterial infections in young infants in developing countries. The WHO Young Infants Study Group. Pediatr Infect Dis J. 1999;18:S23-S31. PMID:10530570 The WHO Young Infants Study Group* (Manary MJ). Methodology for a multicenter study of serious infections in young infants in developing countries. The WHO Young Infants Study Group. Pediatr Infect Dis J. 1999;18:S8-S16. PMID:10530568 The WHO Young Infants Study Group* (Manary MJ). Serious infections in young infants in developing countries: rationale for a multicenter study. The WHO Young Infants Study Group. Pediatr Infect Dis J. 1999;18:S4-S7. PMID:10530567 The WHO young Infants Study Group* (Manary MJ). Bacterial etiology of serious infections in young infants in developing countries: results of a multicenter study. The WHO Young Infants Study Group. Pediatr Infect Dis J. 1999;18:S17-S22. PMID:10530569 The WHO Young Infants Study Group* (Manary MJ). Conclusions from the WHO multicenter study of serious infections in young infants. The WHO Young Infants Study Group. Pediatr Infect Dis J. 1999;18:S32-S34. PMID:10530571 Manary MJ, Hart CA, Whyte MP. Severe hypophosphatemia in children with kwashiorkor is associated with increased mortality. J Pediatr. 1998;133(6):789-791. PMID:9842046 Brewster DR, Manary MJ, Graham SM. Case Management of Kwashiorkor: An Intervention Project at 7-Nutrition Rehabilitation Centres n Malawi Malawi Medical Journal. 1998;11:15-20.
Manary MJ, Broadhead RL, Yarasheski KE. Whole-body protein kinetics in marasmus and kwashiorkor during acute infection. Am J Clin Nutr. 1998;67:1205-1209. PMID:9625094 Manary MJ, Brewster DR. Potassium Supplementation in Kwashiorkor Malawi Medical Journal. 1998;11:6-10.
Manary MJ, Brewster DR, Broadhead RL, Graham SM, Hart CA, Crowley JR, Fjeld CR, Yarasheski KE. Whole-body protein kinetics in children with kwashiorkor and infection: a comparison of egg white and milk as dietary sources of protein. Am J Clin Nutr. 1997;66:643-648. PMID:9280187 Manary MJ, Brewster DR. Potassium supplementation in kwashiorkor. J Gastroenterol Nutr. 1997;24:194-201. PMID:9106107 Manary MJ, Brewster DR, Broadhead RL, Crowley JR, Fjeld CR, Yarasheski KE. Protein metabolism in children with edematous malnutrition and acute lower respiratory infection. Am J Clin Nutr. 1997;65(4):1005-1010. PMID:9094886 Brewster DR, Manary MJ, Menzies IS, Henry RL, O'Loughlin EV. Comparison of milk and maize based diets in kwashiorkor. Arch Dis Child. 1997;76(3):242-248. PMCID:PMC1717098 PMID:9135266 Brewster DR, Manary MJ, Menzies IS, O'Loughlin EV, Henry RL. Intestinal permeability in kwashiorkor. Arch Dis Child. 1997;76(3):236-241. PMCID:PMC1717121 PMID:9135265 Brewster DR, Manary MJ, Graham SM. Case management of kwashiorkor: an intervention project at seven nutrition rehabilitation centres in Malawi. Eur J Clin Nutr. 1997;51(3):139-147. PMID:9076403 Manary MJ, Jaffe DM. Cervical spine injuries in children. Pediatr Ann. 1996;25(8):423-8. PMID:8863317 Dyke T, Lewis D, Heegaard W, Manary M, Flew S, Rudeen K. Predicting hypoxia in children with acute lower respiratory infection: a study in the highlands of Papua New Guinea. J Trop Pediatr. 1995;41(4):196-201. PMID:7563269 Brewster D, Manary M. Treatment of severe malnutrition. Lancet. 1995;345(8947):453. PMID:7741871 Manary MJ, Hollifield WC Jr. Childhood sledding injuries in 1990-91. Pediatr Emerg Care. 1993;9(3):155-8. PMID:8346090 Dyke T, Manary M. Chest infections in African children. Clinical signs unreliable. BMJ. 1993;306(6888):1342. PMCID:PMC1677771 PMID:8518589 Manary MJ, Lehmann D, Michael A, Coakley K, Taime J, Montgomery J, Granoff DM. Antigenuria in healthy Papua New Guinean children with nasal Haemophilus influenzae type b carriage. Ann Trop Paediatr. 1993;13(4):385-389. PMID:7506888 Manary MJ, Keating JP, Hirshberg GE. Quadriparesis due to potassium depletion. Crit Care Med. 1986;14(8):750-752. PMID:3720335 Darmaun D, Manary MJ, Matthews DE. A method for measuring both glutamine and glutamate levels and stable isotopic enrichments. Anal Biochem. 1985;147(1):92-102. PMID:4025827