Most people who visit a doctor when they feel unwell seek a diagnosis and a treatment plan. But for some 30 million Americans with rare diseases, their symptoms don’t match well-known disease patterns, sending families on diagnostic odysseys that can last years or even lifetimes.
Category: Research
Today, we’re announcing $2M in funding for a new pediatric brain cancer clinical trial. Dr. Mohamed Abdelbaki’s team is testing a new type of cancer immunotherapy in children with recurrent brain tumors, with funding from a CureSearch Catapult Award. (Links to an external site)
CureSearch for Children’s Cancer announced today that it will award $2 million in funding to support a Phase I clinical trial in 24 children and young adults with recurrent brain tumors, a diagnosis with a devastating prognosis. More than 15,000 children are diagnosed with cancer each year in the U.S. and are in desperate need of […]
Donor-derived cell-free DNA shows potential for early detection kidney transplant rejection
Findings from a study published in Nature Medicine show donor-derived cell-free DNA (dd-cfDNA), also called liquid biopsy, has the potential for early detection of kidney transplant rejection. The international study enrolled a diverse population of nearly 3,000 kidney transplant recipients — both adult and pediatric — from 14 transplantation centers in Europe and the U.S. […]
Gokanapudy Hahn receives Translational Research Award in Pediatric Heart Transplantation from American Heart Association and Enduring Hearts
Lakshmi Gokanapudy Hahn, MD, has received the Translational Research Award in Pediatric Heart Transplantation from the American Heart Association (AHA) and Enduring Hearts for her project titled, “Contemporary Approach to Desensitization: Targeted Therapies for HLA Sensitized Pediatric Heart Transplant Candidates.” Washington University School of Medicine in St. Louis is the primary site out of seven […]
Two pediatricians awarded grants as part of ICTS’s Clinical and Translational Research Funding Program
Washington University Institute of Clinical and Translational Sciences (ICTS) and The Foundation for Barnes-Jewish Hospital have awarded Brian DeBosch, MD, PhD, and Sarah Greene, MD, PhD, grants as part of the 17th annual Clinical and Translational Research Funding Program (CTRFP). This program is the largest internal grant funding program in the ICTS, requiring applicants to […]
Five factors to ensure an infant thrives (Links to an external site)
There are basic resources every baby needs for the best possible chance to develop as a healthy well-functioning human. Start with good nutrition, breast milk if possible. That baby is going to need stimulation, lots of looking, reciprocal interactions, exposure to language and interesting stimuli. If at all possible, you should live in a place […]
WashU Medicine rises to No. 2 in nation in NIH research funding (Links to an external site)
In the realm of biomedical research, securing funding is a testament to an institution’s record of scientific accomplishments and potential for further advances to improve human health. In 2023, Washington University School of Medicine in St. Louis received the second-highest amount of funding from the National Institutes of Health (NIH) of all medical schools nationwide. […]
Discovery of new PI shows value of grants for exploratory research (Links to an external site)
When Dr. Megan Cooper, director of the clinical immunology program and The Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies at St. Louis Children’s Hospital, applied for the Immune Deficiency Foundation’s research grant program in 2018, she didn’t know exactly what she was looking for. She wanted to use the grant to find a genetic explanation […]
Antibiotic treatment in malnourished children improves gut microbiome development (Links to an external site)
Malnutrition threatens the lives of millions of children under age 5, causing about 500,000 deaths per year in low- and middle-income countries. Short courses of antibiotics paired with a therapeutic peanut butter-based food are the standard of care for treating severe acute malnutrition in children — but using antibiotics in this vulnerable population is controversial; […]
$8 million awarded to study root causes of brain cell death in fatal pediatric diseases (Links to an external site)
A large team of researchers at Washington University School of Medicine in St. Louis has received nearly $8 million from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health (NIH) to help determine the root causes of brain cell death in fatal pediatric neurodegenerative diseases.