Zachary A. Vesoulis, MD MSCI

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Assistant Professor of Pediatrics, Newborn Medicine
Newborn Medicine

phone: (314) 454-6148


  • BA, Miami University2005
  • MD, The Ohio State University2009
  • MSCI, Washington University2019


  • Internship, St. Louis Children's Hospital2009 - 2010
  • Residency, St. Louis Children's Hospital2010 - 2011
  • Fellowship, Washington University School of Medicine2011 - 2014

Licensure and Board Certification

  • 2009 - 2021Neonatal Resuscitation Program
  • 2009 - 2021Advanced Cardiac Life Support
  • 2009 - 2021Basic Life Support
  • 2009 - 2021Pediatric Advanced Life Support
  • 2013 - 2017Advanced Trauma Life Support
  • 2014 - PresMO, Medical License
  • 2014 - PresAmerican Board of Pediatrics, General Pediatrics
  • 2016 - PresAmerican Board of Pediatrics, Neonatal-Perinatal Medicine
  • 2018 - PresIL, Medical License

Honors and Awards

  • Miami University Scholar-Leader Award2003
  • Alspaugh Award for Professionalism in the Field of Medicine2005 - 2009
  • James P. Keating Outstanding Resident Award2011
  • PAS Young Investigator's Travel Award2014
  • Outstanding Fellow Teaching Award2014
  • Travel Award, Burroughs Wellcome Fund2016
  • Outstanding Citizenship Award, Clinical Research Training Center2016
  • Early Career Investigator Highlight - Pediatric Research2017
  • James Sutherland Junior Faculty Award2019
  • Jerry Elliott Memorial Lectureship2020
  • Travel Award for Early Career Investigators - International Pediatric Research Foundation2020
  • 2020 Pediatric Research Top Reviewer2021
  • 2021 Pediatric Research Top Reviewer2022

Recent Publications view all (70)

  1. Active normothermia treatment for perioperative temperature management during bedside surgery in the NICU, a case report. J Neonatal Perinatal Med. 2022. PMID:36189609 
  2. A phase-II clinical trial of targeted cerebral near infrared spectroscopy using standardized treatment guidelines to improve brain oxygenation in preterm infants (BOx-II): A study protocol. Contemp Clin Trials. 2022;106886. PMID:35995129 
  3. Improving child health through Big Data and data science. Pediatr Res. 2022. PMCID:PMC9380977  PMID:35974162 
  4. The Impact of Dexmedetomidine Initiation on Cardiovascular Status and Oxygenation in Critically ill Neonates. Pediatr Cardiol. 2022;43(6):1319-1326. PMCID:PMC9296564  PMID:35212773 
  5. Potential risk modifiers for severe intraventricular hemorrhage in very low birthweight infants requiring transport. J Matern Fetal Neonatal Med. 2022;35(15):2988-2991. PMCID:PMC7917146  PMID:32873087 
  6. Trial of Erythropoietin for Hypoxic-Ischemic Encephalopathy in Newborns. N Engl J Med. 2022;387(2):148-159. PMID:35830641 
  7. An Amplitude Integrated EEG Evaluation of Neonatal Opioid Withdrawal Syndrome Am J Perinatol. 2022. doi:10.1055/a-1877-9291  PMID:35709730 
  8. Seizure burden in preterm infants and smaller brain volume at term-equivalent age. Pediatr Res. 2022;91(4):955-961. PMCID:PMC8546006  PMID:33903729 
  9. Low Variability of Blood Pressure Predicts Abnormal Electroencephalogram in Infants with Hypoxic Ischemic Encephalopathy. Am J Perinatol. 2022;39(3):288-297. PMCID:PMC7895863  PMID:32819015 
  10. Proceedings of the 13th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical. J Neonatal Perinatal Med. 2022;15(2):453-465. PMID:35431188 
  11. Proceedings of the 13th International Newborn Brain Conference: Neonatal Neurocritical Care, Seizures, and Continuous EEG monitoring. J Neonatal Perinatal Med. 2022;15(2):467-485. PMID:35431189 
  12. Racial discrepancy in pulse oximeter accuracy in preterm infants. J Perinatol. 2022;42(1):79-85. PMCID:PMC8508473  PMID:34642469 
  13. Antibiotic spectrum index: A new tool comparing antibiotic use in three NICUs. Infect Control Hosp Epidemiol. 2021;1-5. PMCID:PMC9124723  PMID:34812135 
  14. Utilization of the Sharing Antimicrobial Reports for Pediatric Stewardship (SHARPS) Collaborative electronic mailing list (listserv) by healthcare professionals. Infect Control Hosp Epidemiol. 2021;42(9):1118-1120. PMID:33353577 
  15. Early Vital Sign Differences in Very Low Birth Weight Infants with Severe Intraventricular Hemorrhage. Am J Perinatol. 2021. PMID:34450675 
  16. Predicting mortality risk for preterm infants using deep learning models with time-series vital sign data. NPJ Digit Med. 2021;4(1):108. PMCID:PMC8280207  PMID:34262112 
  17. Vital sign metrics of VLBW infants in three NICUs: implications for predictive algorithms. Pediatr Res. 2021;90(1):125-130. PMCID:PMC8376742  PMID:33767372 
  18. Respiratory effects of prolonged prednisolone use in infants with evolving and established Bronchopulmonary dysplasia. Early Hum Dev. 2021;156:105344. PMID:33684601 
  19. Neonatal NIRS monitoring: recommendations for data capture and review of analytics. J Perinatol. 2021;41(4):675-688. PMCID:PMC7883881  PMID:33589724 
  20. Predicting mortality risk for preterm infants using random forest. Sci Rep. 2021;11(1):7308. PMCID:PMC8012581  PMID:33790395 
  21. The hidden consequence of intraventricular hemorrhage: persistent cerebral desaturation after IVH in preterm infants. Pediatr Res. 2021;89(4):869-877. PMCID:PMC8035346  PMID:33038871 
  22. Practical approaches to sedation and analgesia in the newborn. J Perinatol. 2021;41(3):383-395. PMCID:PMC7700106  PMID:33250515 
  23. Clinical and vital sign changes associated with late-onset sepsis in very low birth weight infants at 3 NICUs. J Neonatal Perinatal Med. 2021;14(4):553-561. PMCID:PMC8316489  PMID:33523025 
  24. WU-NEAT: A clinically validated, open-source MATLAB toolbox for limited-channel neonatal EEG analysis. Comput Methods Programs Biomed. 2020;196:105716. PMCID:PMC7606381  PMID:32858282 
  25. Decreasing Unplanned Extubation in the Neonatal ICU With a Focus on Endotracheal Tube Tip Position. Respir Care. 2020;65(11):1648-1654. PMID:32265290 
  26. Cerebellar hemorrhage: a 10-year evaluation of risk factors. J Matern Fetal Neonatal Med. 2020;33(21):3680-3688. PMCID:PMC6717683  PMID:30821542 
  27. Blood Pressure Profiles in Infants With Hypoxic Ischemic Encephalopathy (HIE), Response to Dopamine, and Association With Brain Injury. Front Pediatr. 2020;8:512. PMCID:PMC7479124  PMID:32984221 
  28. The Challenge of Risk Stratification of Infants Born Preterm in the Setting of Competing and Disparate Healthcare Outcomes. J Pediatr. 2020;223:194-196. PMCID:PMC7476078  PMID:32711746 
  29. Racial disparities in calculated risk for bronchopulmonary dysplasia: a dataset. Data Brief. 2020;30:105674. PMCID:PMC7248447  PMID:32478148 
  30. Mining reported adverse events induced by potential opioid-drug interactions. JAMIA Open. 2020;3(1):104-112. PMCID:PMC7309259  PMID:32607492 
  31. Poverty and Excess Length of Hospital Stay in Neonatal Opioid Withdrawal Syndrome. J Addict Med. 2020;14(2):113-118. PMCID:PMC6881526  PMID:31149915 
  32. Propranolol for the Treatment of Lymphatic Malformations in a Neonate - A Case Report and Review of Literature. J Pediatr Pharmacol Ther. 2020;25(2):155-162. PMCID:PMC7025746  PMID:32071591 
  33. Blood pressure extremes and severe IVH in preterm infants. Pediatr Res. 2020;87(1):69-73. PMCID:PMC6962547  PMID:31578033 
  34. Neurodevelopmental Outcomes in Neonates with Mild Hypoxic Ischemic Encephalopathy Treated with Therapeutic Hypothermia. Am J Perinatol. 2019;36(13):1337-1343. PMCID:PMC6609494  PMID:30609430 
  35. Progressive anemia of prematurity is associated with a critical increase in cerebral oxygen extraction. Early Hum Dev. 2019;140:104891. PMCID:PMC7180102  PMID:31669878 
  36. Delayed cord clamping is associated with improved dynamic cerebral autoregulation and decreased incidence of intraventricular hemorrhage in preterm infants. J Appl Physiol (1985). 2019;127(1):103-110. PMID:31046516 
  37. Early red cell transfusion is associated with development of severe retinopathy of prematurity. J Perinatol. 2019;39(3):393-400. doi:doi: 10.1038/s41372-018-0274-9. Epub 2018 Nov 20.  PMCID:PMC6391181  PMID:30459388 
  38. Acetaminophen Serum Concentrations in Infants Treated Intravenously for Patent Ductus Arteriosus. J Pediatr Pharmacol Ther. 2019;24(2):134-137. PMCID:PMC6478358  PMID:31019406 
  39. Early hypoxemia burden is strongly associated with severe intracranial hemorrhage in preterm infants. J Perinatol. 2019;39(1):48-53. PMCID:PMC6298838  PMID:30267001 
  40. Late failure of cerebral autoregulation in hypoxic-ischemic encephalopathy is associated with brain injury: a pilot study. Physiol Meas. 2018;39(12):125004. PMCID:PMC6289666  PMID:30270845 
  41. A Web-Based Calculator for the Prediction of Severe Neurodevelopmental Impairment in Preterm Infants Using Clinical and Imaging Characteristics. Children (Basel). 2018;5(11). PMCID:PMC6262423  PMID:30441798 
  42. Anemia of prematurity and cerebral near-infrared spectroscopy: should transfusion thresholds in preterm infants be revised? J Perinatol. 2018;38(8):1022-1029. PMCID:PMC6136959  PMID:29740185 
  43. Long term electroencephalography in preterm neonates: Safety and quality of electrode types. Clin Neurophysiol. 2018;129(7):1366-1371. PMCID:PMC6211181  PMID:29729590 
  44. Re-examining the arterial cord blood gas pH screening criteria in neonatal encephalopathy. Arch Dis Child Fetal Neonatal Ed. 2018;103(4):F377-F382. PMCID:PMC6192544  PMID:28942435 
  45. Delayed cord clamping and inotrope use in preterm infants. J Matern Fetal Neonatal Med. 2018;31(10):1327-1334. PMCID:PMC5650549  PMID:28372510 
  46. Term-equivalent functional brain maturational measures predict neurodevelopmental outcomes in premature infants. Early Hum Dev. 2018;119:68-72. PMCID:PMC6190680  PMID:29579560 
  47. Divergent risk factors for cerebellar and intraventricular hemorrhage. J Perinatol. 2018;38(3):278-284. PMCID:PMC5906141  PMID:29242571 
  48. Gestational age-dependent relationship between cerebral oxygen extraction and blood pressure. Pediatr Res. 2017;82(6):934-939. PMCID:PMC5685915  PMID:28902182 
  49. Early career investigator highlight-December. Pediatr Res. 2017;82(6):893. PMID:29068432 
  50. Acetaminophen for Patent Ductus Arteriosus in Extremely Low-Birth-Weight Neonates. J Pediatr Pharmacol Ther. 2017;22(6):461-466. PMCID:PMC5736259  PMID:29290747 
  51. A validated clinical MRI injury scoring system in neonatal hypoxic-ischemic encephalopathy. Pediatr Radiol. 2017;47(11):1491-1499. PMCID:PMC6219383  PMID:28623417 
  52. Delayed Umbilical Cord Clamping at <32 Weeks' Gestation: Implementation and Outcomes. Am J Perinatol. 2017;34(11):1048-1053. PMCID:PMC5578907  PMID:28561189 
  53. Impact of brain injury on functional measures of amplitude-integrated EEG at term equivalent age in premature infants. J Perinatol. 2017;37(8):947-952. PMCID:PMC5578901  PMID:28492522 
  54. Low-frequency blood pressure oscillations and inotrope treatment failure in premature infants. J Appl Physiol (1985). 2017;123(1):55-61. PMCID:PMC6157481  PMID:28428252 
  55. The effect of therapeutic hypothermia on heart rate variability. J Perinatol. 2017;37(6):679-683. PMCID:PMC5446282  PMID:28383534 
  56. Cerebral Autoregulation, Brain Injury, and the Transitioning Premature Infant. Front Pediatr. 2017;5:64. PMCID:PMC5377300  PMID:28421173 
  57. Safety and Short-Term Outcomes of Therapeutic Hypothermia in Preterm Neonates 34-35 Weeks Gestational Age with Hypoxic-Ischemic Encephalopathy. J Pediatr. 2017;183:37-42. PMCID:PMC5367984  PMID:27979578 
  58. The role of post-mortem MRI in the neonatal intensive care unit. J Perinatol. 2017;37(1):98-103. PMCID:PMC5215703  PMID:27654494 
  59. Early hyperoxia burden detected by cerebral near-infrared spectroscopy is superior to pulse oximetry for prediction of severe retinopathy of prematurity. J Perinatol. 2016;36(11):966-971. PMCID:PMC5079836  PMID:27559717 
  60. Early High-Dose Caffeine Increases Seizure Burden in Extremely Preterm Neonates: A Preliminary Study. J Caffeine Res. 2016;6(3):101-107. PMCID:PMC5031091  PMID:27679737 
  61. Response to dopamine in prematurity: a biomarker for brain injury? J Perinatol. 2016;36(6):453-8. PMCID:PMC4882223  PMID:26890555 
  62. Response to dopamine in prematurity: a biomarker for brain injury? J Perinatol. 2016;36(5):410. PMID:27109233 
  63. Empirical estimation of the normative blood pressure in infants <28 weeks gestation using a massive data approach. J Perinatol. 2016;36(4):291-5. doi:10.1038/jp.2015.185  PMCID:PMC4808440  PMID:26633144 
  64. A novel method for assessing cerebral autoregulation in preterm infants using transfer function analysis. Pediatr Res. 2016;79(3):453-9. doi:10.1038/pr.2015.238  PMCID:PMC4821724  PMID:26571222 
  65. Normative amplitude-integrated EEG measures in preterm infants. J Perinatol. 2015;35(6):428-33. doi:10.1038/jp.2014.225  PMCID:PMC4447544  PMID:25521561 
  66. Minoxidil-associated anorexia in an infant with refractory hypertension. Pharmacotherapy. 2014;34(12):e341-4. doi:10.1002/phar.1495  PMID:25280267 
  67. Neuro-Behçets in a Child. Child Neurol Open. 2014;1(1):2329048X14550505. PMCID:PMC5417034  PMID:28503582 
  68. Advances in management of neonatal seizures. Indian J Pediatr. 2014;81(6):592-8. doi:10.1007/s12098-014-1457-9  PMCID:PMC4338003  PMID:24796413 
  69. Early electrographic seizures, brain injury, and neurodevelopmental risk in the very preterm infant. Pediatr Res. 2014;75(4):564-9. doi:10.1038/pr.2013.245  PMCID:PMC3961524  PMID:24366515 
  70. Index of Suspicion in the Nursery Case 2: Late Preterm Infant With a Difficult Intubation Neoreviews. 2014;15(15):e99-e103. doi:10.1542/neo.15-3-e99  
Last updated: 10/14/2022
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