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Kimberly S. Quayle, M.D.
quayleks@wustl.edu
Division Chief, Pediatric Emergency Medicine
Dana Brown Chair in Pediatric Emergency Medicine
Professor of Pediatrics, Emergency Medicine
Emergency Medicine
phone: (314) 454-2341
Education
AB,
Summa Cum Laude
,
University of Missouri-Columbia
,
1984
MD,
Washington University School of Medicine
,
1988
Training
Residency in Pediatrics, St. Louis Children's Hospital
,
1988
-
1991
Pediatric Chief Resident, St. Louis Children's Hospital
,
1991
-
1992
Fellowship in Pediatric Emergency Medicine, Washington University in St. Louis School of Medicine
,
1992
-
1994
Licensure and Board Certification
1989
-
Pres
Pediatric Advanced Life Support
1989
Diplomat, National Board of Medical Examiners
1991
-
Pres
Advanced Trauma Life Support
1991
-
Pres
American Board of Pediatrics (General)
1991
-
Pres
MO, Medical Licensure
1992
Sexual Assault Forensic Examination (S.A.F.E.)- Provider
1993
Advanced Cardiac Life Support
1996
-
Pres
American Board of Pediatrics, Subspecialty Pediatric Emergency Medicine
1996
Basic Life Support
2014
-
Pres
American Board of Pediatrics MOC Certification
Honors and Awards
Curators' Scholar, University of Missouri-Columbia
,
1981
- 1984
Phi Beta Kappa, University of Missouri-Columbia
,
1984
Elisabeth L. Demonchaux Prize in Pediatrics, Washington University School of Medicine
,
1988
Outstanding Teacher, Subspecialty Award, St. Louis Children's Hospital, Washington University School of Medicine, Department of Emergency Medicine
,
2002
- 2003
Pediatric Clinical Educator Award, Washington University in St. Louis School of Medicine, Emergency Medicine Residents
,
2008
- 2009
Triple Crown Winner, Children's Direct St. Louis Children's Hospital
,
2012
Completion of the Academic Medical Leadership Program for Physicians and Scientists
,
2017
Triple Crown Winner, Children's Direct
,
2017
2019 Alumni Faculty Achievement Award, Washington University Medical Center Alumni Association
,
2019
Best PEM MD Award, Emergency Medicine Residents
,
2019
WUSM Alumni Association Distinguished Alumni Scholarship Honoree
,
2020
Recent Publications
view all (44)
Publication Co-Authors
Charles Samson, M.D.
Scott Saunders, M.D., Ph.D.
Fahd Ahmad, M.D., M.S.C.I.
Celeste C. Brancato, M.D.
Nikoleta S. Kolovos, M.D.
Mo, Michelle; Guilak, Farshid; Elward, Alexis; Quayle, Kimberly; Thompson, Dominic; Brouillet, Kristen; Luhmann, Scott J.
The Use of Biomarkers in the Early Diagnosis of Septic Arthritis and Osteomyelitis - A Pilot Study
Journal of Pediatric Orthopaedics
.
2022;42
(5):
e526-e532.
doi:
10.1097/BPO.00000000000002052
Glaser NS, Stoner M, Garro A, Myers S, Rewers A, Brown K, Trainor J, Quayle K, McManemy J, DePiero A, Nigrovic L, Tzmenatos L, Shunk J, Olsen C, Casper C, Kuppermann N, Baird S, Ghetti S: for the Pediatric Emergency Care Applied Research Network (PECARN) DKA Fluid Study Group.
Serum Sodium Concentration and Mental Status in Diabetic Ketoacidosis
Pediatrics
.
2021;148; 3; e2021050243.
doi:
10.1542/peds.2021-050243
Bram S, Quayle KS, Schmidt T, Lloyd J, Ellsworth S, Srinivasin M.
Use of a sterile collection process to reduce contaminated peripheral blood cultures
HOSPPEDS
.
2021.
Rewers A, Glaser N, Olsen C, Casper C, Ghetti S, Myers S, Trainor J, Nigrovic L, Garro A, Tzimenatos L, Quayle KS, Kwok M, Stoner M, Schunk J, McManemy J, Brown K, Pilkey D, Fanflik P, Kuhn R, Kuppermann N.
Emerging Therapies: Drugs and Regimens - Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children with Diabetic Ketoacidosis
Diabetes Care
.
2020.
doi:
DC20-3113.R1
Myers SR, Glaser NS, Trainor JL, Nigrovic LE, Garro A, Tzimenatos L, Quayle KS, Kwok MY, Rewers A, Stoner MJ, Schunk JE, McManemy JK, Brown KM, DePiero AD, Olsen CS, Casper TC, Ghetti S, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group..
Frequency and Risk Factors of Acute Kidney Injury During Diabetic Ketoacidosis in Children and Association With Neurocognitive Outcomes.
JAMA Netw Open
.
2020;3
(12):
e2025481.
PMCID:
PMC7718599
PMID:
33275152
Kupperman N, Ghetti S, Glaser N, Olsen C, Casper C, Myers S, Tzimenatos L, Quayle KS, Kwok M, Rewers A, Stoner M, Depiero A, Trainor J, Nigrovic L, Risgarro A, Schunk J, McManemy J, Brown K, Pilkey D, Kinsman S, Dean M, Zuspan S, Fanflik P, Lerner B .
Pathophysiology/Complications - Cognitive Function following Diabetic Ketoacidosis in Children with New Onset or Previously Diagnosed Type 1
Diabetes Care
.
2020;43
(11):
2768-2775.
doi:
10.2337/DC20-0187
PMID:
32962981
DePiero A, Kuppermann N, Brown K, Schunk J, McManemy J, Rewers A, Stoner M, Tzimenatos L, Garro A, Myers SR, Quayle KS, Trainor JL, Kwok MY, Nigrovic L, Olsen C, Casper TC, Ghetti S, Glaser N, and Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group.
Hypertension During Diabetic Ketoacidosis in Children
J Pediatr
.
2020;223:156-163.e5.
doi:
10.1016/j.jpeds.2020.04.066
PMCID:
PMC7414786
PMID:
32387716
Curfman A, Groenendyk J, Markham C, Quayle KS, Turmelle M, Tieken B, Brancato C, Saunders S.
Implementation of Telemedicine in Pediatric and Neonatal Transport
AIRMEDJ-D-19-00069R1
.
2020.
doi:
10.1016/j.amj.2020.04.008
PMID:
32690303
Chamberlain JM, Kapur J, Shinnar S, Elm J, Holsti M, Babcock L, Rogers A, Barsan W, Cloyd J, Lowenstein D, Bleck TP, Conwit R, Meinzer C, Cock H, Fountain NB, Underwood E, Connor JT, Silbergleit R, Neurological Emergencies Treatment Trials., Pediatric Emergency Care Applied Research Network investigators..
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial.
Lancet
.
2020;395
(10231):
1217-1224.
PMID:
32203691
Kapur J, Elm J, Chamberlain JM, Barsan W, Cloyd J, Lowenstein D, Shinnar S, Conwit R, Meinzer C, Cock H, Fountain N, Connor JT, Silbergleit R, NETT and PECARN Investigators..
Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus.
N Engl J Med
.
2019;381
(22):
2103-2113.
PMCID:
PMC7098487
PMID:
31774955
Puffenbarger MS, Ahmad FA, Argent M, Gu H, Samson C, Quayle KS, Saito JM.
Reduction of Computed Tomography Use for Pediatric Closed Head Injury Evaluation at a Nonpediatric Community Emergency Department.
Acad Emerg Med
.
2019;26
(7):
784-795.
PMID:
30428150
Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, Myers SR, Nigrovic LE, Garro A, Brown KM, Quayle KS, Trainor JL, Tzimenatos L, Bennett JE, DePiero AD, Kwok MY, Perry CS 3rd, Olsen CS, Casper TC, Dean JM, Glaser NS, PECARN DKA FLUID Study Group..
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis.
N Engl J Med
.
2018;378
(24):
2275-2287.
PMCID:
PMC6051773
PMID:
29897851
Lee TS, Luhmann JD, Luhmann SJ, Quayle KS.
Pediatric Lawnmower Injuries
Pediatr Emerg Care
.
2017;33
(12):
784-786.
doi:
10.1097/PEC.0000000000001109
PMID:
28398934
Garro A, Chodobski A, Szmydynger-Chodobska J, Shan R, Bialo SR, Bennett J, Quayle K, Rewers A, Schunk JE, Casper TC, Kuppermann N, Glaser N, Pediatric Emergency Care Applied Research Network (PECARN).
Circulating matrix metalloproteinases in children with diabetic ketoacidosis.
Pediatr Diabetes
.
2017;18
(2):
95-102.
doi:
10.1111/pedi.12359
PMID:
26843101
Stanley RM, Johnson MD, Vance C, Bajaj L, Babcock L, Atabaki S, Thomas D, Simon HK, Cohen DM, Rubalcava D, Adelson PD, Bulloch B, Rogers AJ, Mahajan P, Baren J, Lee L, Hoyle J, Quayle K, Casper TC, Dean JM, Kuppermann N.
Challenges Enrolling Children Into Traumatic Brain Injury Trials: An Observational Study
Acad Emerg Med
.
2017;24
(1):
31-39.
doi:
10.1111/acem.13085
PMID:
27618167
Tunik MG, Powell EC, Mahajan P, Schunk JE, Jacobs E, Miskin M, Zuspan SJ, Wootton-Gores S, Atabaki SM, Hoyle JD Jr, Holmes JF Jr, Dayan PS, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN).
Clinical Presentations and Outcomes of Children With Basilar Skull Fractures After Blunt Head Trauma.
Ann Emerg Med
.
2016;68
(4):
431-440.e1.
doi:
10.1016/j.annemergmed.2016.04.058
PMID:
27471139
Borgialli DA, Mahajan P, Hoyle JD Jr, Powell EC, Nadel FM, Tunik MG, Foerster A, Dong L, Miskin M, Dayan PS, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN).
Performance of the Pediatric Glasgow Coma Scale Score in the Evaluation of Children With Blunt Head Trauma.
Acad Emerg Med
.
2016;23
(8):
878-884.
doi:
10.1111/acem.13014
PMID:
27197686
Atabaki SM, Hoyle JD Jr, Schunk JE, Monroe DJ, Alpern ER, Quayle KS, Glass TF, Badawy MK, Miskin M, Schalick WO, Dayan PS, Holmes JF, Kuppermann N.
Comparison of Prediction Rules and Clinician Suspicion for Identifying Children With Clinically Important Brain Injuries After Blunt Head Trauma.
Acad Emerg Med
.
2016;23
(5):
566-575.
doi:
10.1111/acem.12923
PMID:
26825755
Natale JE, Joseph JG, Rogers AJ, Tunik M, Monroe D, Kerrey B, Bonsu BK, Cook LJ, Page K, Adelgais K, Quayle K, Kuppermann N, Holmes JF.
Relationship of Physician-identified Patient Race and Ethnicity to Use of Computed Tomography in Pediatric Blunt Torso Trauma.
Acad Emerg Med
.
2016;23
(5):
584-590.
doi:
10.1111/acem.12943
PMID:
26914184
Lichenstein R, Monroe D, Quayle KS, Miskin M, Cooper A, Gerardi MJ, Callahan JM, Dayan PS, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN).
Television-Related Head Injuries in Children: A Secondary Analysis of a Large Cohort Study of Head-Injured Children in the Pediatric Emergency Care Applied Research Network.
Pediatr Emerg Care
.
2015.
doi:
10.1097/PEC.0000000000000605
PMID:
26555312
Ellison AM, Quayle KS, Bonsu B, Garcia M, Blumberg S, Rogers A, Wootton-Gorges SL, Kerrey BT, Cook LJ, Cooper A, Kuppermann N, Holmes JF, Pediatric Emergency Care Applied Research Network (PECARN), Pediatric Emergency Care Applied Research Network PECARN.
Use of Oral Contrast for Abdominal Computed Tomography in Children With Blunt Torso Trauma.
Ann Emerg Med
.
2015;66
(2):
107-114.e4.
doi:
10.1016/j.annemergmed.2015.01.014
PMID:
25794610
Powell EC, Atabaki SM, Wootton-Gorges S, Wisner D, Mahajan P, Glass T, Miskin M, Stanley RM, Jacobs E, Dayan PS, Holmes JF, Kuppermann N.
Isolated Linear Skull Fractures in Children With Blunt Head Trauma
Pediatrics
.
2015;135
(4):
e851-e857.
Kwok MY, Yen K, Atabaki S, Adelgais K, Garcia M, Quayle K, Kooistra J, Bonsu BK, Page K, Borgialli D, Kuppermann N, Holmes JF.
Sensitivity of plain pelvis radiography in children with blunt torso trauma.
Ann Emerg Med
.
2015;65
(1):
63-71.e1.
doi:
10.1016/j.annemergmed.2014.06.017
PMID:
25086474
Stanley RM, Hoyle JD Jr, Dayan PS, Atabaki S, Lee L, Lillis K, Gorelick MH, Holubkov R, Miskin M, Holmes JF, Dean JM, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN).
Emergency department practice variation in computed tomography use for children with minor blunt head trauma.
J Pediatr
.
2014;165
(6):
1201-1206.e2.
doi:
10.1016/j.jpeds.2014.08.008
PMID:
25294604
Adelgais KM, Kuppermann N, Kooistra J, Garcia M, Monroe DJ, Mahajan P, Menaker J, Ehrlich P, Atabaki S, Page K, Kwok M, Holmes JF, Intra-Abdominal Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN).
Accuracy of the abdominal examination for identifying children with blunt intra-abdominal injuries.
J Pediatr
.
2014;165
(6):
1230-1235.e5.
doi:
10.1016/j.jpeds.2014.08.014
PMID:
25266346
Quayle KS, Powell EC, Mahajan P, Hoyle JD Jr, Nadel FM, Badawy MK, Schunk JE, Stanley RM, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N.
Epidemiology of blunt head trauma in children in U.S. emergency departments.
N Engl J Med
.
2014;371
(20):
1945-1947.
doi:
10.1056/NEJMc1407902
PMID:
25390756
Lee LK, Monroe D, Bachman MC, Glass TF, Mahajan PV, Cooper A, Stanley RM, Miskin M, Dayan PS, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of Pediatric Emergency Care Applied Research Network (PECARN).
Isolated loss of consciousness in children with minor blunt head trauma.
JAMA Pediatr
.
2014;168
(9):
837-843.
doi:
10.1001/jamapediatrics.2014.361
PMID:
25003654
Dayan PS, Holmes JF, Schutzman S, Schunk J, Lichenstein R, Foerster LA, Hoyle J Jr, Atabaki S, Miskin M, Wisner D, Zuspan S, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN).
Risk of traumatic brain injuries in children younger than 24 months with isolated scalp hematomas.
Ann Emerg Med
.
2014;64
(2):
153-162.
doi:
10.1016/j.annemergmed.2014.02.003
PMID:
24635991
Dayan PS, Holmes JF, Atabaki S, Hoyle J Jr, Tunik MG, Lichenstein R, Alpern E, Miskin M, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN).
Association of traumatic brain injuries with vomiting in children with blunt head trauma.
Ann Emerg Med
.
2014;63
(6):
657-665.
doi:
10.1016/j.annemergmed.2014.01.009
PMID:
24559605
Kerrey BT, Rogers AJ, Lee LK, Adelgais K, Tunik M, Blumberg SM, Quayle KS, Sokolove PE, Wisner DH, Miskin ML, Kuppermann N, Holmes JF, Pediatric Emergency Care Applied Research Network.
A multicenter study of the risk of intra-abdominal injury in children after normal abdominal computed tomography scan results in the emergency department.
Ann Emerg Med
.
2013;62
(4):
319-326.
doi:
10.1016/j.annemergmed.2013.04.006
PMID:
23622949
Glaser NS, Ghetti S, Casper TC, Dean JM, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group.
Pediatric diabetic ketoacidosis, fluid therapy, and cerebral injury: the design of a factorial randomized controlled trial.
Pediatr Diabetes
.
2013;14
(6):
435-446.
doi:
10.1111/pedi.12027
PMCID:
PMC3687019
PMID:
23490311
Holmes JF, Lillis K, Monroe D, Borgialli D, Kerrey BT, Mahajan P, Adelgais K, Ellison AM, Yen K, Atabaki S, Menaker J, Bonsu B, Quayle KS, Garcia M, Rogers A, Blumberg S, Lee L, Tunik M, Kooistra J, Kwok M, Cook LJ, Dean JM, Sokolove PE, Wisner DH, Ehrlich P, Cooper A, Dayan PS, Wootton-Gorges S, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN).
Identifying children at very low risk of clinically important blunt abdominal injuries.
Ann Emerg Med
.
2013;62
(2):
107-116.e2.
doi:
10.1016/j.annemergmed.2012.11.009
PMID:
23375510
Rogers AJ, Maher CO, Schunk JE, Quayle K, Jacobs E, Lichenstein R, Powell E, Miskin M, Dayan P, Holmes JF, Kuppermann N, Pediatric Emergency Care Applied Research Network.
Incidental findings in children with blunt head trauma evaluated with cranial CT scans.
Pediatrics
.
2013;132
(2):
e356-363.
doi:
10.1542/peds.2013-0299
PMID:
23878053
Linscott LL, Kessler MM, Kitchin DR, Quayle KS, Hildebolt CF, McKinstry RC, Don S.
CT for pediatric, acute, minor head trauma: clinician conformity to published guidelines.
Am J Neuroradiol
.
2013;34
(6):
1252-1256.
doi:
10.3174/ajnr.A3366
PMID:
23221949
Nigrovic LE, Lillis K, Atabaki SM, Dayan PS, Hoyle J, Tunik MG, Jacobs ES, Monroe D, Wootton-Gorges SW, Miskin M, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of the Pediatric Emergency Care Applied Research Network (PECARN).
The prevalence of traumatic brain injuries after minor blunt head trauma in children with ventricular shunts.
Ann Emerg Med
.
2013;61
(4):
389-393.
doi:
10.1016/j.annemergmed.2012.08.030
PMID:
23122954
Lichenstein R, Glass TF, Quayle KS, Wootton-Gorges SL, Wisner DH, Miskin M, Muizelaar JP, Badawy M, Atabaki S, Holmes JF, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN).
Presentations and outcomes of children with intraventricular hemorrhages after blunt head trauma.
Arch Pediatr Adolesc Med
.
2012;166
(8):
725-731.
doi:
10.1001/archpediatrics.2011.1919
PMID:
22473883
Nigrovic LE, Lee LK, Hoyle J, Stanley RM, Gorelick MH, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N, Traumatic Brain Injury (TBI) Working Group of Pediatric Emergency Care Applied Research Network (PECARN).
Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms.
Arch Pediatr Adolesc Med
.
2012;166
(4):
356-361.
doi:
10.1001/archpediatrics.2011.1156
PMID:
22147762
Holmes JF, Borgialli DA, Nadel FM, Quayle KS, Schambam N, Cooper A, Schunk JE, Miskin ML, Atabaki SM, Hoyle JD, Dayan PS, Kuppermann N, TBI Study Group for the Pediatric Emergency Care Applied Research Network.
Do children with blunt head trauma and normal cranial computed tomography scan results require hospitalization for neurologic observation?
Ann Emerg Med
.
2011;58
(4):
315-322.
doi:
10.1016/j.annemergmed.2011.03.060
PMID:
21683474
Kuppermann N, Holmes JF, Dayan PS, Hoyle JD Jr, Atabaki SM, Holubkov R, Nadel FM, Monroe D, Stanley RM, Borgialli DA, Badawy MK, Schunk JE, Quayle KS, Mahajan P, Lichenstein R, Lillis KA, Tunik MG, Jacobs ES, Callahan JM, Gorelick MH, Glass TF, Lee LK, Bachman MC, Cooper A, Powell EC, Gerardi MJ, Melville KA, Muizelaar JP, Wisner DH, Zuspan SJ, Dean JM, Wootton-Gorges SL, Pediatric Emergency Care Applied Research Network (PECARN).
Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study.
Lancet
.
2009;374
(9696):
1160-1170.
doi:
10.1016/S0140-6736(09)61558-0
PMID:
19758692
Williams KG, Schootman M, Quayle KS, Struthers J, Jaffe DM.
Geographic variation of pediatric burn injuries in a metropolitan area.
Acad Emerg Med
.
2003;10
(7):
743-752.
PMID:
12837649
Marcin JP, Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N, American Academy of Pediatrics, The Pediatric Emergency Medicine Collaborative Research Commitee.
Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edema.
J Pediatr
.
2002;141
(6):
793-797.
PMID:
12461495
Glaser N, Barnett P, McCaslin I, Nelson D, Trainor J, Louie J, Kaufman F, Quayle K, Roback M, Malley R, Kuppermann N, Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics.
Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics.
N Engl J Med
.
2001;344
(4):
264-269.
doi:
10.1056/NEJM200101253440404
PMID:
11172153
Quayle KS, Wick NA, Gnauck KA, Schootman M, Jaffe DM.
Description of Missouri children who suffer burn injuries.
Inj Prev
.
2000;6
(4):
255-258.
PMCID:
PMC1730668
PMID:
11144622
Quayle KS, Jaffe DM, Kuppermann N, Kaufman BA, Lee BC, Park TS, McAlister WH.
Diagnostic testing for acute head injury in children: when are head computed tomography and skull radiographs indicated?
Pediatrics
.
1997;99
(5):
E11.
PMID:
9113968
Last updated: 04/12/2022
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