Department of Pediatrics

Education

• BA, Brown University, 1975
• MD, Yale University School of Medicine, 1980

Training

• Intern/Resident, University of Washington School of Medicine/Children's Orthopedic Hospital and Medical Center, 1980 - 1983
• Senior Fellow, University of Washington School of Medicine, 1983 - 1987
• Fellow, University of Washington School of Medicine and Children's Hospital and Medical Center , 1988 - 1989

Licensure and Board Certification

• 1984 - PresPediatrics - ABP
• 1992 - PresPediatric Gastroenterology - ABP
• 2002 - PresMO
• 2012 - 2012BCS
• 2013The American Board of Pediatrics (ABP) Maintenance of Certification (MOC)
• 2016 - PresAR

Honors and Awards

• American Gastroenterological Association/Blackwell Scientific Research Scholar Award, 1992 - 1995
• Food and Drug Administration Commissioner's Special Citation, 1997 - 1997
• Melvin E. Carnahan Professor of Pediatrics, Endowed Chair, 2004 - Pres

Recent Publications view all (216)

Publication Co-Authors

James Kemp, M.D.

Gregory A. Storch, M.D.

Christopher McPherson

Misty Good, M.D., M.S.

Philip Levy, M.D.

Lori R. Holtz, M.D., M.S.P.H.

Kristine Wylie, Ph.D.

Mark J. Manary, M.D.

Barbara B. Warner, M.D., MSc

Brian DeBosch, M.D., Ph.D.

Thomas Ferkol, M.D.

Anthony R. French, MD, PhD

Aimée Baumann-Dudenhoeffer, M.D.

Charles Samson, M.D.

Rusconi

Avraham Beigelman, M.D.

Todd N. Wylie

Guoyan Zhao

Stephanie A. Fritz, M.D., M.S.C.I.

Paul W. Hruz, M.D., Ph.D.

Samuel Julian, M.D.

Kevin Baszis, M.D.

Washington University has a long tradition of collaboration amongst colleagues.The faculty above have co-authored publications with Phillip I. Tarr, M.D.

1. Schnadower D, Roskind C, VanBuren J, Powell E, Norris J, Tarr PI, Sapien R, O'Connell K, Chun T, Rogers A, Bhatt S, Mahajan P, Gorelick M, Vance C, Dean JM, Freedman SB. Factors Associated with Non-Adherence in an Emergency Department Based Multicenter Randomized Clinical Trial of a Probiotic in Children with Acute Gastroenteritis. Journal of Pediatric Gastroenterology and Nutrition. 2020. doi:10.1097/MPG.0000000000002904  PMID:32804911 
2. Knoop KA, McDonald KG, Coughlin PE, Kulkarni DH, Gustafsson JK, Rusconi B, John V, Ndao IM, Beigelman A, Good M, Warner BB, Elson CO, Hsieh CS, Hogan SP, Tarr PI, Newberry RD. Synchronization of mothers and offspring promotes tolerance and limits allergy. JCI Insight. 2020. doi:10.1172/jci.insight.137943  PMID:32759496 
3. Renganathan A, Warner BB, Tarr PI, Dharnidharka VR. The progression of serum cystatin C concentrations within the first month of life after preterm birth-a worldwide systemati review. Pediatric Nephrology. 2020. doi:10.1007/s00467-020-04543-1  PMID:32757062 
4. Xie J, Pang X, Gillian GAM, Mu Y, Zhuo R, Chui L, Lee BE, Vanderkooi O, Tarr PI, Ali S, MacDonald S, Freedman SB . Influenza Virus Detection in the Stool of Children with Acute Gastroenteritis. Journal of Clinical Virology. 2020. doi:10.1016/j.jcv.2020.104565  PMID:32810839 
5. Tarr GAM, Pang XL, Zhuo R, Lee B, Chui L, Ali S, Vanderkooi O, Michaels-Igbokwe C, Tarr PI, MacDonald S, Currie G, MacDonald J, Kim K, Freedman SB. Attribution of Pediatric Acute Gastroenteritis Episodes and Emergency Department Visits to Norovirus GI and GII. Journal of Infectious Diseases. 2020. doi:10.1093/infdis/jiaa391  PMID:32614406 
6. Knoop K, Coughlin PE, Floyd AN, Ndao IM, Hall-Moore C, Shaikh N, Gasparrini AJ, Rusconi B, Escobedo M, Good M, Warner BB, Tarr PI, Newberry RD. Maternal activation of the EGFR prevents translocation of gut-residing pathogenic Escherichia coli in a model of late-onset neonatal sepsis. Proceedings of the National Academy of Sciences of the United States of America. 2020. doi:10.1073/pnas.1912022117  PMID:32179676  
7. Freedman S, Schnadower D, Tarr PI. The Probiotic Conundrum: Regulatory Confusion, Conflicting Studies, and Safety Concerns. Journal of the American Medical Association. 2020;323(9):823-824. doi:10.1001/jama.2019.22268  PMID:32125410 
8. Ordiz MI, Janssen S, Humphrey G, Ackermann G, Stephenson K, Agapova S, Divala O, Kaimila Y, Maleta K, Zhong C, Knight R, Trehan I, Tarr PI, Rusconi B, Manary MJ. The effect of legume supplementation on the gut microbiota in rural Malawian infants aged 6 to 12 months. American Journal of Clinical Nutrition (E-pub ahead of print). 2020. doi:10.1093/ajcn/nqaa011  PMID:32047925 
9. Tarr GAM, Lin CY, Vandermeer B, Lorenzetti DL, Tarr PI, Chui L, Hartling L, Freedman SB. Diagnostic Test Accuracy of Commercial Tests for Detection of Shiga Toxin-Producing Escherichia coli: A Systematic Review and Meta-Analysis. Clinical Chemistry. 2020;1;66(2):302-315. doi:10.1093/clinchem/hvz006  PMID:32040589 
10. Liu TC, VanBuskirk K, Ali SA, Kelly MP, Holtz LR, Yilmaz OH, Sadiq K, Iqbal N, Amadi B, Syed S, Ahmed T, Moore S, Ndao IM, Isaacs MH, Pfeifer JD, Atlas H, Tarr PI, Denno DM, Moskaluk CA. A novel histological index for evaluation of environmental enteric dysfunction identifies geographic-specific features of enteropathy among children with suboptimal growth. PLOS Neglected Tropical Diseases. 2020. doi:10.1371/journal.pntd.0007975  PMID:31929525 
11. Zhang Y, Shaikh N, Ferey JL, Wankhade UD, Chintapalli SV, Higgins CB, Crowley JR, Heitmeier MR, Stothard AI, Mihi B, Good MR, Higashiyama T, Swarts BM, Hruz PW, Shankar K, Tarr PI, DeBosch BJ. Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice. Gastroenterology. 2019. doi:10.1053/j.gastro.2019.11.295  PMID:31838076 
12. Maqsood R, Rodgers R, Rodriguez C, Handley SA, Ndao IM, Tarr PI, Warner BB, Lim ES, Holtz LR. Discordant transmission of bacteria and viruses from mothers to babies at birth. Microbiome. 2019. doi:10.1186/s40168-019-0766-7  PMID:31823811 
13. Tarr GAM, Stokowski T, Shringi S, Tarr PI, Freedman SB, Oltean HN, Rabinowitz PM, Chui L. Contribution and Interaction of Shiga Toxin Genes to Escherichia coli O157:H7 Virulence. Toxins. 2019. doi:10.3390/toxins11100607  PMID:31635282 
14. Dorshow RB, Johnson JR, Debreczeny MP, Riley IR, Shieh JJ, Rogers TE, Hall-Moore C, Shaikh N, Rouggly-Nickless LC, Tarr PI. Transdermal fluorescence detection of a dual fluorophore system for noninvasive point-of-care gastrointestinal permeability measurement. Biomed Opt Express. 2019. doi:10.1364/BOE.10.005103  PMID:31646033 
15. Gasparrini AJ, Wang B, Sun X, Kennedy EA, Hernandez-Leyva A, Ndao IM, Tarr PI, Warner BB, Dantas G. Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome. Nat Microbiol. 2019. doi:10.1038/s41564-019-0550-2   PMID:31501537 
16. Schnadower D, Tarr PI, Freedman SB. Letter: Lactobacillus rhamnosus GG offers no benefit over placebo in children with acute gastroenteritis. Aliment Pharmacol Ther. 2019. doi:10.1111/apt.15418  PMID:31414542 
17. Hasso-Agopsowicz M, Ladva CN, Lopman B, Sanderson C, Cohen AL, Tate JE, Riveros X, Henao-Restrepo AM, Clark A, Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators. Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination. Clinical Infectious Diseases. 2019. doi:10.1093/cid/ciz060  PMID:30689799 
18. Tarr GAM, Tarr PI, Freedman SB. Clinical interpretation of enteric molecular diagnostic tests. Clinical Microbiology and Infection. 2019. doi:10.1016/j.cmi.2019.08.018  PMID:31491461 
19. Schnadower D, Tarr PI, Freedman SB. Lactobacillus for Gastroenteritis in Children. Reply. N Engl J Med. 2019;380(19):e36. PMID:31067399 
20. Xie Y, Matsumoto H, Kennedy S, Newberry EP, Moritz W, DeBosch BJ, Moley KH, Rubin DC, Warner BW, Kau AL, Tarr PI, Wylie TN, Wylie KM, Davidson NO. Impaired Chylomicron Assembly Modifies Hepatic Metabolism Through Bile Acid-Dependent and Transmissible Microbial Adaptations. Hepatology. 2019;70(4):1168-1184. doi:10.1002/hep.30669  PMCID:PMC6783349  PMID:31004524 
21. Kellner T, Parsons B, Chui L, Berenger BM, Xie J, Burnham CA, Tarr PI, Lee BE, Nettel-Aguirre A, Szelewicki J, Vanderkooi OG, Pang XL, Zelyas N, Freedman SB, Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE). Comparative Evaluation of Enteric Bacterial Culture and a Molecular Multiplex Syndromic Panel in Children with Acute Gastroenteritis. J Clin Microbiol. 2019. PMID:30971465 
22. Xie J, Tarr GAM, Ali S, Chui L, Pang XL, Lee BE, Vanderkooi OG, Tarr PI, Zhuo R, Parsons B, Berenger B, Kim K, Freedman SB, Alberta Provincial Pediatric EnTeric Infection Team (APPETITE) and Pediatric Emergency Research Canada (PERC). Pigment Visibility on Rectal Swabs Used to Detect Enteropathogens: A Prospective Cohort Study. J Clin Microbiol. 2019. PMID:30944189 
23. Ryan RM, Keller RL, Poindexter BB, D'Angio CT, Shaw PA, Bellamy SL, Moore PE, McPherson C, Greenberg JM, PROP Investigators. Respiratory Medications in Infants <29 Weeks during the First Year Postdischarge: The Prematurity and Respiratory Outcomes Program (PROP) Consortium. J Pediatr. 2019. PMID:30857774 
24. Tarr GAM, Lin CY, Lorenzetti D, Chui L, Tarr PI, Hartling L, Vandermeer B, Freedman SB. Performance of commercial tests for molecular detection of Shiga toxin-producing Escherichia coli (STEC): a systematic review and meta-analysis protocol. BMJ Open. 2019;9(3):e025950. PMID:30850413 
25. Ryan RM, Feng R, Bazacliu C, Ferkol TW, Ren CL, Mariani TJ, Poindexter BB, Wang F, Moore PE, Prematurity and Respiratory Outcome Program (PROP) Investigators. Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia J Pediatr. 2019. PMID:30612812 
26. Tarr GAM, Chui L, Lee BE, Pang XL, Ali S, Nettel-Aguirre A, Vanderkooi OG, Berenger BM, Dickinson J, Tarr PI, Drews S, MacDonald J, Kim K, Freedman SB. Performance of Stool Testing Recommendations for Acute Gastroenteritis when Used to Identify Children with Nine Potential Bacterial Enteropathogens. Clin Infect Dis. 2018. PMID:30517612 
27. Tarr GAM, Oltean HN, Phipps AI, Rabinowitz P, Tarr PI. Case definitions of hemolytic uremic syndrome following Escherichia coli O157:H7 infection vary in validity. Int J Med Microbiol. 2018;308(8):1121-1127. PMID:30466555 
28. Schnadower D, Tarr PI, Casper TC, Gorelick MH, Dean JM, O'Connell KJ, Mahajan P, Levine AC, Bhatt SR, Roskind CG, Powell EC, Rogers AJ, Vance C, Sapien RE, Olsen CS, Metheney M, Dickey VP, Hall-Moore C, Freedman SB. Lactobacillus rhamnosus GG versus Placebo for Acute Gastroenteritis in Children. N Engl J Med. 2018;379(21):2002-2014. PMID:30462938 
29. Baumann-Dudenhoeffer AM, D'Souza AW, Tarr PI, Warner BB, Dantas G. Infant diet and maternal gestational weight gain predict early metabolic maturation of gut microbiomes. Nat Med. 2018. PMID:30374198 
30. Tarr GAM, Oltean HN, Phipps AI, Rabinowitz P, Tarr PI. Strength of the association between antibiotic use and hemolytic uremic syndrome following Escherichia coli O157:H7 infection varies with case definition. Int J Med Microbiol. 2018;308(7):921-926. PMID:30257808 
31. Stang AS, Trudeau M, Vanderkooi OG, Lee BE, Chui L, Pang XL, Allen V, Burnham CD, Goldfarb DM, MacDonald J, Parsons B, Petrich A, Pollari F, Tarr PI, Tipples G, Zhuo R, Freedman SB. Diagnostic Interpretation Guidance for Pediatric Enteric Pathogens: A Modified Delphi Consensus Process. Can J Infect Dis Med Microbiol. 2018;2018:2589826. PMCID:PMC6180965  PMID:30363711 
32. Rusconi B, Jiang X, Sidhu R, Ory DS, Warner BB, Tarr PI. Gut Sphingolipid Composition as a Prelude to Necrotizing Enterocolitis. Sci Rep. 2018;8(1):10984. PMID:30030452 
33. Xie J, Nettel-Aguirre A, Lee BE, Chui L, Pang XL, Zhuo R, Parsons B, Vanderkooi OG, Tarr PI, Ali S, Dickinson JA, Hagen E, Svenson LW, MacDonald SE, Drews SJ, Tellier R, Graham T, Lavoie M, MacDonald J, Freedman SB, Pediatric Emergency Research Canada (PERC) and the Alberta Provincial Pediatric EnTeric Infection Team (APPETITE Team). Relationship between Enteric Pathogen and Acute Gastroenteritis Disease Severity - A Prospective Cohort Study. Clin Microbiol Infect. 2018. PMID:29964235 
34. Tarr GAM, Shringi S, Oltean HN, Mayer J, Rabinowitz P, Wakefield J, Tarr PI, Besser TE, Phipps AI. Importance of case age in the purported association between phylogenetics and hemolytic uremic syndrome in Escherichia coli O157:H7 infections. Epidemiol Infect. 2018;1-6. PMID:29914582 
35. McKee RS, Tarr PI, Dietzen DJ, Chawla R, Schnadower D. Clinical and Laboratory Predictors of Shiga Toxin-Producing Escherichia coli Infection in Children With Bloody Diarrhea. J Pediatric Infect Dis Soc. 2018. PMID:29617871 
36. Blaisdell CJ, Troendle J, Zajicek A, Prematurity and Respiratory Outcomes Program.. Acute Responses to Diuretic Therapy in Extremely Low Gestational Age Newborns: Results from the Prematurity and Respiratory Outcomes Program Cohort Study. J Pediatr. 2018. PMID:29599068 
37. Chandrasekaran S, Burnham CD, Warner BB, Tarr PI, Wylie TN. Carriage of Cronobacter sakazakii in the very preterm infant gut. Clin Infect Dis. 2018. PMID:29394356 
38. Tarr GAM, Shringi S, Phipps AI, Besser TE, Mayer J, Oltean HN, Wakefield J, Tarr PI, Rabinowitz P. Geogenomic Segregation and Temporal Trends of Human Pathogenic Escherichia coli O157:H7, Washington, USA, 2005-2014¹. Emerg Infect Dis. 2018;24(1):32-39. PMCID:PMC5749469  PMID:29260688 
39. Knoop KA, Gustafsson JK, McDonald KG, Kulkarni DH, Coughlin PE, McCrate S, Kim D, Hsieh CS, Hogan SP, Elson CO, Tarr PI, Newberry RD. Microbial antigen encounter during a preweaning interval is critical for tolerance to gut bacteria. Sci Immunol. 2017;2(18). PMCID:PMC5759965  PMID:29246946 
40. Denno DM, Tarr PI, Nataro JP. Environmental Enteric Dysfunction: A Case Definition for Intervention Trials. Am J Trop Med Hyg. 2017;97(6):1643-1646. PMID:29016294 
41. Shane AL, Mody RK, Crump JA, Tarr PI, Steiner TS, Kotloff K, Langley JM, Wanke C, Warren CA, Cheng AC, Cantey J, Pickering LK. 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea. Clin Infect Dis. 2017;65(12):1963-1973. PMID:29194529 
42. Fotis L, Shaikh N, Baszis KW, Samson CM, Lev-Tzion R, French AR, Tarr PI. Serologic Evidence of Gut-driven Systemic Inflammation in Juvenile Idiopathic Arthritis. J Rheumatol. 2017;44(11):1624-1631. PMID:28916545 
43. Rusconi B, Good M, Warner BB. The Microbiome and Biomarkers for Necrotizing Enterocolitis: Are We Any Closer to Prediction? J Pediatr. 2017;189:40-47.e2. PMCID:PMC5614810  PMID:28669607 
44. Schnadower D, Tarr PI, Casper TC, Gorelick MH, Dean MJ, O'Connell KJ, Mahajan P, Chun TH, Bhatt SR, Roskind CG, Powell EC, Rogers AJ, Vance C, Sapien RE, Gao F, Freedman SB. Randomised controlled trial of Lactobacillus rhamnosus (LGG) versus placebo in children presenting to the emergency department with acute gastroenteritis: the PECARN probiotic study protocol. BMJ Open. 2017;7(9):e018115. PMCID:PMC5623493  PMID:28947466 
45. Dorshow RB, Hall-Moore C, Shaikh N, Talcott MR, Faubion WA, Rogers TE, Shieh JJ, Debreczeny MP, Johnson JR, Dyer RB, Singh RJ, Tarr PI. Measurement of gut permeability using fluorescent tracer agent technology. Sci Rep. 2017;7(1):10888. PMCID:PMC5589723  PMID:28883476 
46. Melamed R, Storch GA, Holtz LR, Klein EJ, Herrin B, Tarr PI, Denno DM. Case-Control Assessment of the Roles of Noroviruses, Human Bocaviruses 2, 3, and 4, and Novel Polyomaviruses and Astroviruses in Acute Childhood Diarrhea. J Pediatric Infect Dis Soc. 2017;6(3):e49-e54. PMID:28186546 
47. Stout MJ, Zhou Y, Wylie KM, Tarr PI, Macones GA, Tuuli MG. Early pregnancy vaginal microbiome trends and preterm birth. Am J Obstet Gynecol. 2017;217(3):356.e1-356.e18. PMCID:PMC5581228  PMID:28549981 
48. Freedman SB, Xie J, Nettel-Aguirre A, Lee B, Chui L, Pang XL, Zhuo R, Parsons B, Dickinson JA, Vanderkooi OG, Ali S, Osterreicher L, Lowerison K, Tarr PI, Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE).. Enteropathogen detection in children with diarrhoea, or vomiting, or both, comparing rectal flocked swabs with stool specimens: an outpatient cohort study. Lancet Gastroenterol Hepatol. 2017;2(9):662-669. PMID:28712662 
49. Amadi B, Besa E, Zyambo K, Kaonga P, Louis-Auguste J, Chandwe K, Tarr PI, Denno DM, Nataro JP, Faubion W, Sailer A, Yeruva S, Brantner T, Murray J, Prendergast AJ, Turner JR, Kelly P. Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia. EBioMedicine. 2017;22:191-199. PMCID:PMC5552244  PMID:28750860 
50. Barron LK, Warner BB, Tarr PI, Shannon WD, Deych E, Warner BW. Independence of gut bacterial content and neonatal necrotizing enterocolitis severity. J Pediatr Surg. 2017;52(6):993-998. PMCID:PMC5473614  PMID:28410788 
51. Pammi M, Cope J, Tarr PI, Warner BB, Morrow AL, Mai V, Gregory KE, Kroll JS, McMurtry V, Ferris MJ, Engstrand L, Lilja HE, Hollister EB, Versalovic J, Neu J. Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis. Microbiome. 2017;5(1):31. PMCID:PMC5343300  PMID:28274256 
52. Ordiz MI, Stephenson K, Agapova S, Wylie KM, Maleta K, Martin J, Trehan I, Tarr PI, Manary MJ. Environmental Enteric Dysfunction and the Fecal Microbiota in Malawian Children. Am J Trop Med Hyg. 2017;96(2):473-476. PMCID:PMC5303055  PMID:27956653 
53. Grisaru S, Xie J, Samuel S, Hartling L, Tarr PI, Schnadower D, Freedman SB, Alberta Provincial Pediatric Enteric Infection Team. Associations Between Hydration Status, Intravenous Fluid Administration, and Outcomes of Patients Infected With Shiga Toxin-Producing Escherichia coli: A Systematic Review and Meta-analysis. JAMA Pediatr. 2017;171(1):68-76. PMID:27893870 
54. Ordiz MI, Shaikh N, Trehan I, Maleta K, Stauber J, Shulman R, Devaraj S, Tarr PI, Manary MJ. Environmental Enteric Dysfunction Is Associated With Poor Linear Growth and Can Be Identified by Host Fecal mRNAs. J Pediatr Gastroenterol Nutr. 2016;63(5):453-459. PMCID:PMC5084633  PMID:27347722 
55. Gasparrini AJ, Crofts TS, Gibson MK, Tarr PI, Warner BB, Dantas G. Antibiotic perturbation of the preterm infant gut microbiome and resistome. Gut Microbes. 2016;7(5):443-9. PMCID:PMC5154371  PMID:27472377 
56. Rusconi B, Sanjar F, Koenig SS, Mammel MK, Tarr PI, Eppinger M. Whole Genome Sequencing for Genomics-Guided Investigations of Escherichia coli O157:H7 Outbreaks. Front Microbiol. 2016;7:985. PMCID:PMC4928038  PMID:27446025 
57. Planer JD, Peng Y, Kau AL, Blanton LV, Ndao IM, Tarr PI, Warner BB, Gordon JI. Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice. Nature. 2016;534(7606):263-6. PMCID:PMC4902178  PMID:27279225 
58. Freedman SB, Xie J, Neufeld MS, Hamilton WL, Hartling L, Tarr PI, Alberta Provincial Pediatric Enteric Infection Team (APPETITE), Nettel-Aguirre A, Chuck A, Lee B, Johnson D, Currie G, Talbot J, Jiang J, Dickinson J, Kellner J, MacDonald J, Svenson L, Chui L, Louie M, Lavoie M, Eltorki M, Vanderkooi O, Tellier R, Ali S, Drews S, Graham T, Pang XL. Shiga Toxin-Producing Escherichia coli Infection, Antibiotics, and Risk of Developing Hemolytic Uremic Syndrome: A Meta-analysis. Clin Infect Dis. 2016;62(10):1251-1258. PMCID:PMC4845788  PMID:26917812 
59. Warner BB, Deych E, Zhou Y, Hall-Moore C, Weinstock GM, Sodergren E, Shaikh N, Hoffmann JA, Linneman LA, Hamvas A, Khanna G, Rouggly-Nickless LC, Ndao IM, Shands BA, Escobedo M, Sullivan JE, Radmacher PG, Shannon WD, Tarr PI. Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study. Lancet. 2016;387(10031):1928-36. PMCID:PMC5553277  PMID:26969089 
60. Stauber J, Shaikh N, Ordiz MI, Tarr PI, Manary MJ. Droplet digital PCR quantifies host inflammatory transcripts in feces reliably and reproducibly. Cell Immunol. 2016;303:43-9. PMCID:PMC4863679  PMID:27063479 
61. Gibson MK, Wang B, Ahmadi S, Burnham CA, Tarr PI, Warner BB, Dantas G. Developmental dynamics of the preterm infant gut microbiota and antibiotic resistome. Nat Microbiol. 2016;1:16024. PMCID:PMC5031140  PMID:27572443 
62. Yu J, Ordiz MI, Stauber J, Shaikh N, Trehan I, Barnell E, Head RD, Maleta K, Tarr PI, Manary MJ. Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair Processes. Cell Mol Gastroenterol Hepatol. 2016;2(2):158-174.e1. PMCID:PMC4769221  PMID:26973864 
63. Gurnee EA, Ndao IM, Johnson JR, Johnston BD, Gonzalez MD, Burnham CA, Hall-Moore CM, McGhee JE, Mellmann A, Warner BB, Tarr PI. Gut Colonization of Healthy Children and Their Mothers With Pathogenic Ciprofloxacin-Resistant Escherichia coli. J Infect Dis. 2015;212(12):1862-8. PMCID:PMC4655851  PMID:25969564 
64. Poindexter BB, Feng R, Schmidt B, Aschner JL, Ballard RA, Hamvas A, Reynolds AM, Shaw PA, Jobe AH, Prematurity and Respiratory Outcomes Program. Comparisons and Limitations of Current Definitions of Bronchopulmonary Dysplasia for the Prematurity and Respiratory Outcomes Program Ann Am Thorac Soc. 2015;12(12):1822-30. PMCID:PMC4722827  PMID:26397992 
65. Julian S, Burnham CA, Sellenriek P, Shannon WD, Hamvas A, Tarr PI, Warner BB. Impact of neonatal intensive care bed configuration on rates of late-onset bacterial sepsis and methicillin-resistant Staphylococcus aureus colonization. Infect Control Hosp Epidemiol. 2015;36(10):1173-82. PMCID:PMC5089903  PMID:26108888 
66. Lim ES, Zhou Y, Zhao G, Bauer IK, Droit L, Ndao IM, Warner BB, Tarr PI, Wang D, Holtz LR. Early life dynamics of the human gut virome and bacterial microbiome in infants. Nat Med. 2015;21(10):1228-34. PMCID:PMC4710368  PMID:26366711 
67. Ordiz MI, May TD, Mihindukulasuriya K, Martin J, Crowley J, Tarr PI, Ryan K, Mortimer E, Gopalsamy G, Maleta K, Mitreva M, Young G, Manary MJ. The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children. Microbiome. 2015;3:37. doi:10.1186/s40168-015-0102-9  PMCID:PMC4558878  PMID:26334878 
68. Freedman SB, Lee BE, Louie M, Pang XL, Ali S, Chuck A, Chui L, Currie GR, Dickinson J, Drews SJ, Eltorki M, Graham T, Jiang X, Johnson DW, Kellner J, Lavoie M, MacDonald J, MacDonald S, Svenson LW, Talbot J, Tarr P, Tellier R, Vanderkooi OG. Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE): epidemiology, emerging organisms, and economics. BMC Pediatr. 2015;15:89. PMCID:PMC4521468  PMID:26226953 
69. Qin X, Klein EJ, Galanakis E, Thomas AA, Stapp JR, Rich S, Buccat AM, Tarr PI. Real-Time PCR Assay for Detection and Differentiation of Shiga Toxin-Producing Escherichia coli from Clinical Samples. J Clin Microbiol. 2015;53(7):2148-53. PMCID:PMC4473226  PMID:25926491 
70. Zhang Y, Rowehl L, Krumsiek JM, Orner EP, Shaikh N, Tarr PI, Sodergren E, Weinstock GM, Boedeker EC, Xiong X, Parkinson J, Frank DN, Li E, Gathungu G. Identification of Candidate Adherent-Invasive E. coli Signature Transcripts by Genomic/Transcriptomic Analysis. PLoS One. 2015;10(6):e0130902. PMCID:PMC4509574  PMID:26125937 
71. VanDussen KL, Marinshaw JM, Shaikh N, Miyoshi H, Moon C, Tarr PI, Ciorba MA, Stappenbeck TS. Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays. Gut. 2015;64(6):911-20. PMCID:PMC4305344  PMID:25007816 
72. Maitre NL, Ballard RA, Ellenberg JH, Davis SD, Greenberg JM, Hamvas A, Pryhuber GS, Prematurity and Respiratory Outcomes Program. Respiratory consequences of prematurity: evolution of a diagnosis and development of a comprehensive approach. J Perinatol. 2015;35(5):313-21. doi:10.1038/jp.2015.19  PMCID:PMC4414744  PMID:25811285 
73. Pryhuber GS, Maitre NL, Ballard RA, Cifelli D, Davis SD, Ellenberg JH, Greenberg JM, Kemp J, Mariani TJ, Panitch H, Ren C, Shaw P, Taussig LM, Hamvas A, Prematurity and Respiratory Outcomes Program Investigators.. Prematurity and respiratory outcomes program (PROP): study protocol of a prospective multicenter study of respiratory outcomes of preterm infants in the United States. BMC Pediatr. 2015;15:37. PMCID:PMC4407843  PMID:25886363 
74. Kuczius T, Zhang W, Merkel V, Mellmann A, Tarr PI, Karch H. Agitation down-regulates immunoglobulin binding protein EibG expression in Shiga toxin-producing Escherichia coli (STEC). PLoS One. 2015;10(3):e0119583. PMCID:PMC4352079  PMID:25746924 
75. Moore AM, Ahmadi S, Patel S, Gibson MK, Wang B, Ndao MI, Deych E, Shannon W, Tarr PI, Warner BB, Dantas G. Gut resistome development in healthy twin pairs in the first year of life. Microbiome. 2015;3:27. doi:10.1186/s40168-015-0090-9  PMCID:PMC4480905  PMID:26113976 
76. Sommovilla J, Zhou Y, Sun RC, Choi PM, Diaz-Miron J, Shaikh N, Sodergren E, Warner BB, Weinstock GM, Tarr PI, Warner BW. Small bowel resection induces long-term changes in the enteric microbiota of mice. J Gastrointest Surg. 2015;19(1):56-64; discussion 64. PMCID:PMC4576885  PMID:25183407 
77. Zhou Y, Burnham CA, Hink T, Chen L, Shaikh N, Wollam A, Sodergren E, Weinstock GM, Tarr PI, Dubberke ER. Phenotypic and genotypic analysis of Clostridium difficile isolates: a single-center study. J Clin Microbiol. 2014;52(12):4260-6. PMCID:PMC4313296  PMID:25275005 
78. Schindler EI, Sellenriek P, Storch GA, Tarr PI, Burnham CA. Shiga toxin-producing Escherichia coli: a single-center, 11-year pediatric experience. J Clin Microbiol. 2014;52(10):3647-53. PMCID:PMC4187762  PMID:25078916 
79. La Rosa PS, Warner BB, Zhou Y, Weinstock GM, Sodergren E, Hall-Moore CM, Stevens HJ, Bennett WE Jr, Shaikh N, Linneman LA, Hoffmann JA, Hamvas A, Deych E, Shands BA, Shannon WD, Tarr PI. Patterned progression of bacterial populations in the premature infant gut. Proc Natl Acad Sci U S A. 2014;111(34):12522-7. PMCID:PMC4151715  PMID:25114261 
80. Carl MA, Ndao IM, Springman AC, Manning SD, Johnson JR, Johnston BD, Burnham CA, Weinstock ES, Weinstock GM, Wylie TN, Mitreva M, Abubucker S, Zhou Y, Stevens HJ, Hall-Moore C, Julian S, Shaikh N, Warner BB, Tarr PI. Sepsis from the gut: the enteric habitat of bacteria that cause late-onset neonatal bloodstream infections. Clin Infect Dis. 2014;58(9):1211-8. PMCID:PMC3982840  PMID:24647013 
81. Bielaszewska M, Schiller R, Lammers L, Bauwens A, Fruth A, Middendorf B, Schmidt MA, Tarr PI, Dobrindt U, Karch H, Mellmann A. Heteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6. EMBO Mol Med. 2014;6(3):347-57. PMCID:PMC3958309  PMID:24413188 
82. Sanjar F, Hazen TH, Shah SM, Koenig SS, Agrawal S, Daugherty S, Sadzewicz L, Tallon LJ, Mammel MK, Feng P, Soderlund R, Tarr PI, Debroy C, Dudley EG, Cebula TA, Ravel J, Fraser CM, Rasko DA, Eppinger M. Genome Sequence of Escherichia coli O157:H7 Strain 2886-75, Associated with the First Reported Case of Human Infection in the United States. Genome Announc. 2014;2(1). PMCID:PMC3886948  PMID:24407635 
83. Gurnee EA, Ndao IM, McGhee JE, Warner BB, Tarr PI, Fritz SA, Burnham CA. Fecal carriage of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus in healthy children. Antimicrob Agents Chemother. 2014;58(2):1261-2. PMCID:PMC3910844