Magee Lab

Critical insights into causes of childhood leukemia and pioneering prevention strategies our lab investigates how leukemias arise from normal blood-forming stem cells, how malignant cells hijack developmental programs and why childhood and adult leukemias differ genetically. Using innovative mouse models we study leukemia evolution during early life and assess how stressors such as chemotherapy contribute to disease. Our goal is to develop new approaches to treat and ultimately prevent childhood leukemia.