Items

Advancing treatments for blood diseases through innovative cellular therapy research, our center focuses on immune regulation in hematopoietic stem cell transplantation and the development of novel platforms for cell-based therapies. By uncovering mechanisms of immune tolerance, enhancing regulatory immune cells to prevent graft-versus-host disease and designing safer cancer-targeting strategies, we aim to transform HSCT into a more effective and less toxic cure. Our bench-to-bedside approach drives breakthroughs that offer patients long, healthy lives.

Research profile

Advancing research to transform outcomes for children with cancer, our center unites scientists and clinicians to tackle the leading cause of disease-related death among U.S. children. Despite progress in treatment, cancer still claims young lives and leaves survivors facing lifelong challenges such as hearing loss, learning difficulties, heart damage, infertility and secondary cancers. Through innovative basic and applied research, we strive to develop safer cures while reducing long-term complications.

The McDonnell Pediatric Research Building (MPRB) is an 11-story facility spanning 227,000 square feet. It features six floors of pediatric research laboratories, supporting both new programs and the expansion of existing ones. Common core facilities within the building serve more than 200 physician-scientists and trainees, fostering collaboration and innovation.

As a focal point for cutting-edge research into childhood diseases, the MPRB drives the application of basic science and technological discoveries to improve clinical care for children.

On the first floor, you’ll find the Farmstead Café—a rustic yet modern space offering locally sourced breakfast, coffee, soups, salads and sandwiches.

Shared spaces

Offering a comprehensive and advanced educational experience, this one-year ACGME-accredited subspecialty program is designed for board-certified or board-eligible medical geneticists seeking expertise in managing children and adults with inborn errors of metabolism. It is ideal for those planning academic careers in medical genetics and genomics with a specific focus on metabolic disorders.

Offering advanced training in medical genetics, this two-year ACGME-accredited program is designed for physicians who have completed a prior residency and seek a career in genetics. The program provides comprehensive clinical and academic preparation in partnership with WashU Medicine and St. Louis Children’s Hospital.

Building meaningful connections, our mentorship programs foster professional development and personal growth for trainees and faculty. Through guidance, collaboration and shared experience, we aim to strengthen skills, expand networks and support success across the WashU Medicine community.

Reducing stress and improving focus, Move into Mindfulness offers free programs for WashU employees year-round. From Mind Body Stress Reduction series and drop-in sessions to healing workshops and a curated mindfulness library, these resources provide practical skills for balance and well-being.

Advancing imaging research and innovation, the Molecular Microbiology Imaging Facility provides resources, expertise and collaborative opportunities for scientists and clinicians. From cutting-edge imaging technologies to data analysis tools and training programs, this platform supports multidisciplinary efforts to improve diagnostics, treatment and understanding of complex biological systems.