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Dickson Lab

Patricia Dickson, MD
Division of Genetics and Genomic Medicine

The Dickson laboratory studies the mucopolysaccharidosis (MPS) disorders, which are lysosomal enzyme deficiencies affecting the catabolism of glycosaminoglycans. Central nervous system manifestations include progressive intellectual disability, communicating hydrocephalus, dysmyelination, spinal cord compression, and cortical atrophy. Our lab studies cerebrospinal fluid delivery of recombinant enzymes to treat central nervous disease due to MPS, and has demonstrated biodistribution of intrathecally-delivered recombinant enzymes throughout the neuroaxis of MPS models, with correction of lysosomal storage. The laboratory also studies neuroimaging and neuropathology of white matter in MPS brain and the humoral immune responses to therapeutic enzymes. Projects range from bench to bedside including clinical trials.

Research profile

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DIFFS

Diversity and Inclusion Forum for Faculty & Staff

Our mission is to build a strong culture of inclusion and advocate support for an influential community of underrepresented faculty and staff by creating opportunities for networking, mentoring, cultural awareness, and collaboration.

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Diversity & Inclusion at WashU

Washington University's initiatives to support and cultivate a stronger climate of diversity and inclusion.

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Emergency Medicine

The Division of Emergency Medicine provides clinical care to patients seen at two locations: St. Louis Children’s Hospital Emergency Department, an ACS-verified Level 1 pediatric trauma center and Northwest Healthcare in North St. Louis County. The division also includes the Section of Child Abuse Pediatrics, whose members care for children with suspected physical or sexual abuse in inpatient and outpatient settings.

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Emergency Medicine

Division of Emergency Medicine

Program aims to produce physicians who are master clinicians specializing in the care of acutely ill and injured children.  In addition to receiving outstanding clinical training, our program trains fellows to become expert educators and to perform research that will enrich their practice and expand the field of emergency medicine.  The fellowship emphasizes individualized learning plans, flexible elective time and robust mentoring to help fellows develop skills and expertise to pursue fulfilling career paths based on their personal interests.

Emergency Medicine

Emergency Medicine

Our division provides clinical care to patients seen at two locations: St. Louis Children’s Hospital Emergency Department, an ACS-verified Level 1 pediatric trauma center and Northwest Healthcare in North St. Louis County. The division also includes the Section of Child Abuse Pediatrics, whose members care for children with suspected physical or sexual abuse in inpatient and outpatient settings.  Our division offers fellowship training in pediatric emergency medicine and child abuse pediatrics.

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Endocrinology & Diabetes

The Division of Pediatric Endocrinology and Diabetes provides comprehensive specialty care and consultative services children from the greater St. Louis area and the four-state surrounding region each year. We also provide outpatient services at locations throughout the bistate area. We offer the very latest in diagnostic and therapeutic services for the full range of endocrine-metabolic disorders.

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Endocrinology & Diabetes

Endocrinology & Diabetes

Through excellence in patient care, research, advocacy and education, we aim to improve the lives of children and adolescents with diabetes and endocrine disorders.

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Endocrinology Fellowship

Division of Endocrinology & Diabetes

A three-year comprehensive ACGME-accredited program for pediatricians interested in pursuing an academic medical career in pediatric endocrinology. Whether you aim to be a master clinician, an attending in an academic institution, or a basic science or clinical researcher, our faculty will help you to establish yourself as a leader in pediatric endocrinology.