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Research profile

Established in 2014, the Pediatric Global Health Residency Pathway at St. Louis Children’s Hospital offers residents specialized training in global child health. Beginning in the second year, participants complete a two-week course featuring lectures, simulation labs and local experiences and are encouraged to pursue an international elective with financial and logistical support. Past electives have included sites across Africa, the Caribbean and Asia, and opportunities have resumed post-pandemic. Global health education also extends to all residents through integrated lectures and journal clubs.

Supporting successful grant management, this collection of links provides essential resources for post-award needs. From agency policy guidelines and financial management tools to publication requirements and presentation support, these references help investigators navigate compliance, reporting and dissemination of research effectively.

Helping investigators prepare competitive proposals, this collection of links provides essential resources for pre-award grant needs. From PI eligibility and internal funding opportunities to external agency guidelines, searchable databases and writing guides, these tools support researchers in navigating requirements and securing funding for innovative projects.

Investigating the origins of genome instability in childhood cancers, our lab seeks to understand how DNA damage responses shape tumor development and therapeutic outcomes. Unlike adult malignancies driven by aging or environmental carcinogens, pediatric cancers arise through distinct mechanisms that remain poorly understood. Our long-term goal is to identify predictors of mutagenesis and uncover vulnerabilities within DNA damage response pathways, paving the way for innovative treatments that improve survival and quality of life for children with cancer.

Research profile

Investigating cross-generational epigenetic regulation and its impact on health and disease, the Greer Lab explores how non-genetic information shapes complex physiological and pathological traits across generations. By studying molecular determinants of epigenetic memory, we aim to uncover how environmental changes influence health, development and longevity, and how disruptions in these mechanisms contribute to disease. Our research seeks to illuminate the processes behind epigenetic inheritance and identify strategies to improve outcomes for future generations.

Research profile

Helping employees and their households navigate work and personal demands, GuidanceResources offers free, 24/7 access to counseling and resources through the Employee Assistance Program. With confidential consultations, referrals and digital tools, the program ensures you have support whenever you need it.

Exploring mechanisms and differences in artery development in the context of extracellular matrix gene mutations our lab studies how vascular elastic fibers form and how defects in this process lead to diseases such as aneurysms and hypertension. Using models with fibulin-4 mutations we investigate why large arteries show fragmented fibers while small arteries remain intact, aiming to uncover how these differences contribute to aneurysm development.

Research profile

Expanding regional collaboration to strengthen sickle cell care, this network supports coordinated service delivery, bundled prevention and treatment services, professional training and improved continuity of care across eight states. Led by WashU Medicine as the region’s technical assistance center, the program brings together clinicians, families and community partners to advance comprehensive, evidence-based care and improve quality of life for people with sickle cell disease.

Delivering nationally recognized pulmonary care for children our team combines advanced diagnostics, innovative treatments and multidisciplinary expertise to manage a full range of respiratory conditions. With more than 12,000 outpatient consultations annually, we provide comprehensive, family-centered care supported by leading physicians and state-of-the-art technology.

Pediatric Leukemia & Lymphoma Program • Heartland Southwest Sickle Cell Disease Network