Shenoy Lab

Developing safer less toxic hematopoietic stem cell transplantation in children our research focuses on reduced intensity transplantation for hemoglobinopathies such as sickle cell disease and thalassemia using the best available related or alternate donors. Building on multi-center trials like the SCURT trial for severe sickle cell disease and the URTH trial for thalassemia we are now exploring reduced intensity approaches for non-malignant disorders using minimally mismatched marrow or cord blood donors.