Critical Care Medicine
Bubeck-Wardenburg Lab
Juliane Bubeck-Wardenburg, MD, PhD
Division of Critical Care Medicine
Driving innovative approaches to combat infectious diseases by advancing the understanding of host-pathogen interactions, our lab is dedicated to uncovering how bacteria interact with the host, evade immune defenses and develop antibiotic resistance. Through an interdisciplinary team blending molecular microbiology, immunology and genetic analysis, we aim to identify new therapeutic targets and strategies that address some of the most pressing global health challenges.
Clemens Lab
Regina Clemens, MD, PhD
Division of Critical Care Medicine
Exploring molecular mechanisms of neutrophil activation, our laboratory investigates how these critical immune cells shape host defense and influence health and disease. Focusing on the consequences of neutrophil dysregulation, we study its role in driving severe inflammation and contributing to pathology in conditions such as sepsis, organ transplant, acute lung injury and stroke, with the goal of identifying strategies to restore balance and improve patient outcomes.
Katira Lab
Bhushan Katira, MBBS
Division of Critical Care Medicine
Exploring novel mechanisms of lung injury during mechanical ventilation and critical care, the Katira Lab is dedicated to developing personalized strategies for respiratory support and lung protection in critically ill patients. Leveraging expertise in large animal models and advanced cardio-respiratory tools such as electrical impedance tomography, we translate cutting-edge research into approaches that improve outcomes and redefine standards of care.
Said Lab
Ahmed Sameh Said, MD, PhD
Division of Critical Care Medicine
Enhancing pediatric critical care through predictive models and decision support tools, our team specializes in translational biomedical informatics to transform high-resolution EHR data into actionable insights. By developing machine learning-driven solutions that integrate seamlessly into clinical workflows, we aim to improve decision-making at the bedside and advance personalized care for critically ill children.
Steed Lab
Ashley L. Steed, MD, PhD
Division of Critical Care Medicine
Exploring host antiviral responses to commensal and pathogenic interactions, our research focuses on uncovering the mechanisms that drive innate immune defenses against viral infections. We also investigate how the microbiota influences the establishment and maintenance of antiviral immunity, aiming to reveal insights that inform new strategies for disease prevention and treatment.