Newborn Medicine
Cardiac Neurosciences Group
Cynthia M. Ortinau, MD, MSCI
Division of Newborn Medicine
Our research team studies brain development, brain injury, and neurodevelopmental outcomes of children with congenital heart disease.
Luke-Pak-Silverman Lab
Clifford J. Luke, PhD
Stephen C. Pak, PhD
Gary A. Silverman, MD, PhD
Division of Newborn Medicine
We are a multi-PI lab with a primary interest in understanding the role of serpins (serine proteinase inhibitors) in normal physiology and disease. Serpins play important roles in maintaining cellular homeostasis by regulating the activity of their target proteases. As such, an imbalance in the protease-serpin equilibrium can lead to cellular dysfunction, tissue damage and death.
Luke research profile
Pak research profile
Silverman research profile
Neonatal Neurology & Physiology Research Lab
Zachary A. Vesoulis, MD, MSCI
Division of Newborn Medicine
Our lab focuses on understanding the physiologic basis for brain injury in neonates, as well as the development of new methodologies for prediction of neurologic injury. The ultimate goal of these efforts is the development of new strategies for neonatal neuroprotection.
Wambach-Cole Lab
Jennifer A. Wambach, MD
F. Sessions Cole, MD
Division of Newborn Medicine
Our lab is interested in understanding the genetic causes of rare diseases and birth defects among infants and children. Our research goals are to use genomic sequencing technologies including whole exome and genome sequencing, RNASeq and gene expression studies to identify the genetic causes of rare diseases and birth defects among infants and children and to use functional studies to determine the disease mechanisms underlying these rare diseases.