Rheumatology & Immunology

Uncovering the viral roots of autoimmune disease to advance understanding and treatment, our lab investigates how infections disrupt immune regulation and trigger chronic conditions. By studying roseolovirus and other thymus-targeting viruses, we aim to reveal mechanisms that lead to loss of immune tolerance, autoreactive cell development and lifelong predisposition to autoimmunity. Using advanced immunologic and molecular virology tools, we strive to identify therapeutic targets and strategies that improve outcomes for millions affected by autoimmune disorders.

Research profile

Investigating the origins of immune-mediated disorders in children, the Cooper lab focuses on uncovering genetic mechanisms that contribute to pediatric immune dysregulation. Using advanced genomic sequencing, we identify genetic causes of disease and employ both in vitro and in vivo models to deepen understanding of these conditions. Our work emphasizes leveraging cutting-edge sequencing technologies to reveal mechanisms underlying undiagnosed immune deficiencies in children.

Research profile